Standout Papers
Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
An enumerative algorithm for de novo design of proteins with diverse pocket structures
2020 StandoutNobel
Principles for designing proteins with cavities formed by curved β sheets
2017 StandoutScienceNobel
Protein homology model refinement by large-scale energy optimization
2018 StandoutNobel
Exploiting conformational dynamics to modulate the function of designed proteins
2023 StandoutNobel
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
2020 StandoutNobel
Computational Stabilization of a Non‐Heme Iron Enzyme Enables Efficient Evolution of New Function
2024 StandoutNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
Capture‐C reveals preformed chromatin interactions between HIF ‐binding sites and distant promoters
2016 StandoutNobel
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Changes in the intestine microbial, digestion and immunity of Litopenaeus vannamei in response to dietary resistant starch
2019 Standout
Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells
2020 StandoutNobel
De novo design of immunoglobulin-like domains
2022 StandoutNobel
Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau
2018
Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes
2020 Standout
The molecular hallmarks of epigenetic control
2016 Standout
Local unfolding of the HSP27 monomer regulates chaperone activity
2019
Maintaining a Healthy Proteome during Oxidative Stress
2018
Isotopically-coded short-range hetero-bifunctional photo-reactive crosslinkers for studying protein structure
2014
Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): role of PKC, MAPKs, and NF-κB
2008
Hallmarks of aging: An expanding universe
2023 Standout
Chemical shift-based methods in NMR structure determination
2018
Opportunities and challenges in design and optimization of protein function
2024
NMR spectroscopy captures the essential role of dynamics in regulating biomolecular function
2021
Quality Control of Membraneless Organelles
2018
Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases
2015 Standout
In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus
2018 Standout
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
2019 Standout
Discovery of curcumin, a component of golden spice, and its miraculous biological activities
2011 Standout
Engineering enhanced protein disaggregases for neurodegenerative disease
2015
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Protein sequence optimization with a pairwise decomposable penalty for buried unsatisfied hydrogen bonds
2021 StandoutNobel
Cellular and Molecular Basis of Pulmonary Arterial Hypertension
2009
Characterization and function analysis of Hsp60 and Hsp10 under different acute stresses in black tiger shrimp, Penaeus monodon
2015
Intrinsically disordered proteins in cellular signalling and regulation
2014 Standout
H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs
2012
Design of multi-scale protein complexes by hierarchical building block fusion
2021 StandoutNobel
Structural and Functional Analysis of JMJD2D Reveals Molecular Basis for Site-Specific Demethylation among JMJD2 Demethylases
2012
Frozen in Time: The History of Proteins
2017
De novo design of a non-local β-sheet protein with high stability and accuracy
2018 StandoutNobel
<p>Reactive Oxygen Species: Drivers of Physiological and Pathological Processes</p>
2020 Standout
Repurposing Hsp104 to Antagonize Seminal Amyloid and Counter HIV Infection
2015 StandoutNobel
Chromatin as an oxygen sensor and active player in the hypoxia response
2011
Histone 3 Lysine 9 Trimethylation Is Differentially Associated With Isocitrate Dehydrogenase Mutations in Oligodendrogliomas and High-Grade Astrocytomas
2013
The proteostasis network and its decline in ageing
2019
O-GlcNAc modification of small heat shock proteins enhances their anti-amyloid chaperone activity
2021 StandoutNobel
Deep learning and protein structure modeling
2022 StandoutNobel
Simple yet functional phosphate-loop proteins
2018 StandoutNobel
Digoxin inhibits development of hypoxic pulmonary hypertension in mice
2012 StandoutNobel
Accurate design of megadalton-scale two-component icosahedral protein complexes
2016 StandoutScienceNobel
Rapid Sampling of Hydrogen Bond Networks for Computational Protein Design
2018 StandoutNobel
Torsional and Electronic Factors Control the C−H⋅⋅⋅O Interaction
2016
Development of IsoTaG, a Chemical Glycoproteomics Technique for Profiling Intact N- and O-Glycopeptides from Whole Cell Proteomes
2017 StandoutNobel
Defining efficient enzyme–cofactor pairs for bioorthogonal profiling of protein methylation
2013
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
The Distinct Conformational Landscapes of 4S‐Substituted Prolines That Promote an endo Ring Pucker
2019
Physicochemical Properties of Cells and Their Effects on Intrinsically Disordered Proteins (IDPs)
2014
2015 StandoutNobel
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
2016 StandoutScienceNobel
The Origin of Chalcogen-Bonding Interactions
2017 Standout
Catalytic Asymmetric Hydroalkoxylation of C–C Multiple Bonds
2021 StandoutNobel
Protein structure prediction using multiple deep neural networks in the 13th Critical Assessment of Protein Structure Prediction (CASP13)
2019 StandoutNobel
Simultaneous Optimization of Biomolecular Energy Functions on Features from Small Molecules and Macromolecules
2016 StandoutNobel
Natural and Designed Proteins Inspired by Extremotolerant Organisms Can Form Condensates and Attenuate Apoptosis in Human Cells
2022 StandoutNobel
The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design
2017 StandoutNobel
Microglial M1/M2 polarization and metabolic states
2015 Standout
Essentials of de novo protein design: Methods and applications
2018
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
Chalcogen Bonding: An Overview
2018 Standout
Computational Design of Stable and Soluble Biocatalysts
2018
Combined Covalent-Electrostatic Model of Hydrogen Bonding Improves Structure Prediction with Rosetta
2015 StandoutNobel
Inhibition of the Cysteine Protease Human Cathepsin L by Triazine Nitriles: Amide⋅⋅⋅Heteroarene π‐Stacking Interactions and Chalcogen Bonding in the S3 Pocket
2016
Works of Scott Horowitz being referenced
Carbon-Oxygen Hydrogen Bonding in Biological Structure and Function
2012
Protein unfolding as a switch from self-recognition to high-affinity client binding
2016
Forces Driving Chaperone Action
2016
Do nucleic acids moonlight as molecular chaperones?
2016
Computational Redesign of Thioredoxin Is Hypersensitive toward Minor Conformational Changes in the Backbone Template
2016
Structure and Function of Histone H3 Lysine 9 Methyltransferases and Demethylases
2011
Direct Evidence for Methyl Group Coordination by Carbon-Oxygen Hydrogen Bonds in the Lysine Methyltransferase SET7/9
2011
Increased arginase activity and endothelial dysfunction in human inflammatory bowel disease
2007
Visualizing chaperone-assisted protein folding
2016
Human esophageal microvascular endothelial cells respond to acidic pH stress by PI3K/AKT and p38 MAPK-regulated induction of Hsp70 and Hsp27
2006
Capturing a Dynamic Chaperone–Substrate Interaction Using NMR-Informed Molecular Modeling
2016
Super Spy variants implicate flexibility in chaperone action
2014
Sulfur–Oxygen Chalcogen Bonding Mediates AdoMet Recognition in the Lysine Methyltransferase SET7/9
2015
Utility of 1H NMR Chemical Shifts in Determining RNA Structure and Dynamics
2013