Citation Impact
Citing Papers
Systemic Delivery of Microencapsulated 3-Bromopyruvate for the Therapy of Pancreatic Cancer
2014 StandoutNobel
Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins
2016
Crystal Structure and Mechanism of Activation of TANK-Binding Kinase 1
2013
Plasma Hsp90 levels in patients with systemic sclerosis and relation to lung and skin involvement: a cross-sectional and longitudinal study
2021 Standout
Interstitial lung disease in connective tissue diseases: evolving concepts of pathogenesis and management
2010
Transition from inflammation to proliferation: a critical step during wound healing
2016 Standout
Scoring functions for protein–protein interactions
2013 StandoutNobel
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
Fibrosis in Systemic Sclerosis
2008
NF-κB signaling in inflammation
2017 Standout
Cellular and molecular mechanisms of fibrosis
2007 Standout
Effects of Flavonoids and other Polyphenols on Inflammation
2011 Standout
Development of TGF-β signalling inhibitors for cancer therapy
2004
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
2010 Standout
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
2012 Standout
An official European Respiratory Society/American Thoracic Society research statement: interstitial pneumonia with autoimmune features
2015 Standout
Computer-aided drug discovery and development (CADDD): In silico-chemico-biological approach
2006
Smad3‐dependent signaling underlies the TGF‐β1‐mediated enhancement in astrocytic iNOS expression
2010
NF-κB, the first quarter-century: remarkable progress and outstanding questions
2012 Standout
Crystal structure of inhibitor of κB kinase β
2011 Nature
Cell-Based Assays for High-Throughput Screening
2010
Generation of Receptor Structural Ensembles for Virtual Screening Using Binding Site Shape Analysis and Clustering
2012
Transforming growth factor-β in cancer and metastasis
2006
Inhibition of transforming growth factor-β via the activin receptor-like kinase-5 inhibitor attenuates pulmonary fibrosis
2015
Fibrosis in systemic sclerosis: Emerging concepts and implications for targeted therapy
2010
Computational Methods in Drug Discovery
2014
Scleroderma
2009 Standout
Essential Roles for Early Growth Response Transcription Factor Egr-1 in Tissue Fibrosis and Wound Healing
2009
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
The complexity of NF-κB signaling in inflammation and cancer
2013 Standout
Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments
2013 Standout
Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology
2006 Standout
Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises
2011 Standout
Extracellular matrix structure
2015 Standout
Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
2007 Standout
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Breaking the chains: structure and function of the deubiquitinases
2009 Standout
NEMO specifically recognizes K63‐linked poly‐ubiquitin chains through a new bipartite ubiquitin‐binding domain
2009
The IKK Complex, a Central Regulator of NF- B Activation
2009
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Crystal structure of the NEMO ubiquitin‐binding domain in complex with Lys 63‐linked di‐ubiquitin
2009
IKK Regulation and Human Genetics
2010
Identification of a unique TGF-β–dependent molecular and functional signature in microglia
2013 Standout
Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach
2018 Standout
Remodelling the extracellular matrix in development and disease
2014 Standout
Molecular requirements for epithelial–mesenchymal transition during tumor progression
2005 Standout
SwissParam: A fast force field generation tool for small organic molecules
2011 Standout
Systemic sclerosis: a prototypic multisystem fibrotic disorder
2007 Standout
Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN
2009 Standout
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
2008 Standout
Extracellular Matrix Molecules: Potential Targets in Pharmacotherapy
2009
Pancreatic Cancer
2010 Standout
A Nuclear Poly(ADP-Ribose)-Dependent Signalosome Confers DNA Damage-Induced IκB Kinase Activation
2009
Applications of machine learning in drug discovery and development
2019 Standout
Comprehensive analysis of kinase inhibitor selectivity
2011 Standout
Endoglin and Alk5 regulate epithelial–mesenchymal transformation during cardiac valve formation
2006
A semiempirical free energy force field with charge‐based desolvation
2007 Standout
Enhancements of screening collections to address areas of unmet medical need: an industry perspective
2010
TGF-β-induced epithelial to mesenchymal transition
2009 Standout
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
High-throughput docking as a source of novel drug leads
2004
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation
2009
Impact of high-throughput screening in biomedical research
2011 Standout
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Trends in Kinase Selectivity: Insights for Target Class-Focused Library Screening
2010
Cell-Permeable Bicyclic Peptidyl Inhibitors against NEMO-IκB Kinase Interaction Directly from a Combinatorial Library
2018
Structural Interaction Fingerprint (SIFt): A Novel Method for Analyzing Three-Dimensional Protein−Ligand Binding Interactions
2003
NEMO oligomerization and its ubiquitin-binding properties
2009
Recent applications of deep learning and machine intelligence on in silico drug discovery: methods, tools and databases
2018
Molecular Docking and Structure-Based Drug Design Strategies
2015 Standout
Docking and scoring in virtual screening for drug discovery: methods and applications
2004 Standout
The extracellular matrix at a glance
2010 Standout
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
Molecular Docking: Shifting Paradigms in Drug Discovery
2019 Standout
Relationship between Hot Spot Residues and Ligand Binding Hot Spots in Protein–Protein Interfaces
2012
On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1
2012 Standout
Stromal regulation of vessel stability by MMP14 and TGFβ
2010
A Novel Small-Molecule Inhibitor of Transforming Growth Factor β Type I Receptor Kinase (SM16) Inhibits Murine Mesothelioma Tumor Growth In vivo and Prevents Tumor Recurrence after Surgical Resection
2007
Linear polyubiquitination: a new regulator of NF‐κB activation
2009
A possible link between resveratrol and TGF‐β: Resveratrol induction of TGF‐β expression and signaling
2008
The Ubiquitin Code
2012 Standout
Molecular Basis of NF-κB Signaling
2013
Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010
2012 Standout
Tumor-stroma interactions in pancreatic ductal adenocarcinoma
2007
Works of Scott Bowes being referenced
Quality Assessment and Analysis of Biogen Idec Compound Library
2006
Successful shape-Based virtual screening: The discovery of a potent inhibitor of the type I TGFβ receptor kinase (TβRI)
2003
Adopting a Practical Statistical Approach for Evaluating Assay Agreement in Drug Discovery
2005
Structure of a NEMO/IKK-Associating Domain Reveals Architecture of the Interaction Site
2008
Intracellular TGF-β Receptor Blockade Abrogates Smad-Dependent Fibroblast Activation In Vitro and In Vivo
2006
A Kinase‐focused Compound Collection: Compilation and Screening Strategy
2006