Standout Papers
Citation Impact
Citing Papers
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist
2004 StandoutNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Inadequate erythropoietin response to anemia: definition and clinical relevance
1994
Hypoxia, a Novel Inducer of Acute Phase Gene Expression in a Human Hepatoma Cell Line
1995
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Multiple signaling pathways are involved in erythropoietin-independent differentiation of erythroid progenitors in polycythemia vera
2004
Functional diversity of helper T lymphocytes
1996 StandoutNature
The role of inflammation in the anaemia of end-stage renal disease
2001
Identification of the renal erythropoietin-producing cells using transgenic mice
1993 StandoutNobel
Erythroid development of the FDCP‐Mix A4 multipotent cell line is governed by the relative concentrations of erythropoietin and interleukin 3
1995
Pathogenesis and treatment of anaemia of chronic disease
2002
Erythropoietin receptor. Subunit structure and activation.
1990
An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice: A cytokine receptor superfamily oncogene
1991
Increased Expression of Erythropoiesis Inhibiting Cytokines (IFN-γ, TNF-α, IL-10, and IL-13) by T Cells in Patients Exhibiting a Poor Response to Erythropoietin Therapy
2003
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
Acute event‐related anaemia
2001
Erythropoietin processing in erythropoietic system and central nervous system
1995
Photoaffinity labeling of the erythropoietin receptor and its identification in a ligand-free form
1991
Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial
2003 Standout
Pathogenesis of polycythaemia vera
1997
Cysteine Promoted C‐Terminal Hydrazinolysis of Native Peptides and Proteins
2013 StandoutNobel
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
1998 StandoutNatureNobel
Analysis of Cis‐acting Sequences Required for Operation of the Erythropoietin 3’Enhancer in Different Cell Linesa
1994 StandoutNobel
STAT3 is constitutively active in some patients with Polycythemia rubra vera
2001
Erythropoietin stimulates proliferation of human renal carcinoma cells
2000
Cellular sites of extrarenal and renal erythropoietin production in anaemic rats
1992
Iron status and the outcome of HIV infection: an overview
2001
Impaired Expression of the Thrombopoietin Receptor by Platelets from Patients with Polycythemia Vera
1998
Hypoxia-induced Transcriptional Activation and Increased mRNA Stability of Vascular Endothelial Growth Factor in C6 Glioma Cells
1995
Spontaneous megakaryocyte colony formation in myeloproliferative disorders is not neutralizable by antibodies against IL3, IL6 and GM‐CSF
1994
Interleukin-10-deficient mice develop chronic enterocolitis
1993 Standout
Interferon‐γ exerts its negative regulatory effect primarily on the earliest stages of murine erythroid progenitor cell development
1995
Functional Significance of Erythropoietin Receptor Expression in Breast Cancer
2002
Characterisation of functional domains within the mouse erythropoietin 3′ enhancer conveying oxygen-regulated responses in different cell lines
1994 StandoutNobel
Erythropoietin regulates tumour growth of human malignancies
2003
Molecular pathogenesis of Philadelphia chromosome negative myeloproliferative disorders
2004
Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins
1994 StandoutScience
Erythropoietin Treatment of Anemia Associated with Multiple Myeloma
1990
Purification and Characterization of Hypoxia-inducible Factor 1
1995 StandoutNobel
A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
1997 StandoutNature
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
2005 Standout
β Phorbol Ester- and Diacylglycerol-Induced Augmentation of Transmitter Release Is Mediated by Munc13s and Not by PKCs
2002 StandoutNobel
Apoptosis of human erythroid colony‐forming cells is decreased by stem cell factor and insulin‐like growth factor I as well as erythropoietin
1993
Erythropoietin as a Retinal Angiogenic Factor in Proliferative Diabetic Retinopathy
2005
Molecular biology of erythropoietin
1993 StandoutNobel
JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin
1993
Production and ligand-binding characteristics of the soluble form of murine erythropoietin receptor
1992
Lineage-Specific Hematopoietic Growth Factors
2006
Effect of iron treatment on circulating cytokine levels in ESRD patients receiving recombinant human erythropoietin
2003
Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor
1995
Iron and immunity: a double‐edged sword
2002
Dimerization, DNA Binding, and Transactivation Properties of Hypoxia-inducible Factor 1
1996 StandoutNobel
HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells
2007 StandoutNobel
Characteristics and clinical relevance of chronic anemia in adult heart transplant recipients
2001
Erythropoietin for the treatment of anemia of malignancy associated with neoplastic bone marrow infiltration.
1990
Prediction of response to iron sucrose in inflammatory bowel disease-associated anemia
2001
Erythropoietin and Erythropoietin Receptor
1999
Convergent Chemical Synthesis of [Lysine24, 38, 83] Human Erythropoietin
2011
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Erythropoietin increases hemoglobin in cancer patients during radiation therapy
1993
Insulin-like growth factors and insulin stimulate erythropoietin production in primary cultured astrocytes
1997
Proinflammatory Cytokines Lowering Erythropoietin Production
1998
Erythropoietin Inhibits Calcium-Induced Neurotransmitter Release from Clonal Neuronal Cells
2000
A Gain-of-Function Mutation of JAK2 in Myeloproliferative Disorders
2005 Standout
The molecular mechanism of erythropoietin action
1992
Anemia of Chronic Disease
2005 Standout
Function of caspases in regulating apoptosis caused by erythropoietin deprivation in erythroid progenitors
1999
Digoxin inhibits development of hypoxic pulmonary hypertension in mice
2012 StandoutNobel
Hypoxic Induction of the Human Erythropoietin Gene: Cooperation between the Promoter and Enhancer, Each of Which Contains Steroid Receptor Response Elements
1992
Erythropoietin, iron, and erythropoiesis
2000
Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy
2015 StandoutNobel
Hypersensitivity of circulating progenitor cells to megakaryocyte growth and development factor (PEG-rHu MGDF) in essential thrombocythemia
2000
Erythropoietin and erythropoietin receptors in the peripheral nervous system: changes after nerve injury
2001
Hypersensitivity of circulating progenitor cells to megakaryocyte growth and development factor (PEG-rHu MGDF) in essential thrombocythemia
2000
In Vitro Development of Primitive and Definitive Erythrocytes from Different Precursors
1996 StandoutScienceNobel
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.
1993 StandoutNobel
New Approaches to Olefin Cross-Metathesis
1999 StandoutNobel
Activation of the mitogen-activated protein kinase pathway by the erythropoietin receptor.
1994
Functional Mimicry of a Protein Hormone by a Peptide Agonist: The EPO Receptor Complex at 2.8 Å
1996 Science
Hypoxia-inducible factor 1α protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations
2000 StandoutNobel
Physiology meets biophysics: Visualizing the interaction of hypoxia-inducible factor 1α with p300 and CBP
2002 StandoutNobel
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
1995 StandoutNobel
Developmental gene expression and tissue distribution of the CHIP28 water-channel protein.
1993 StandoutNobel
Intravenous Iron Optimizes the Response to Recombinant Human Erythropoietin in Cancer Patients With Chemotherapy-Related Anemia: A Multicenter, Open-Label, Randomized Trial
2004
Apoptosis in the Pathogenesis and Treatment of Disease
1995 StandoutScience
Erythropoietin enhancer stimulates production of a recombinant protein by Chinese hamster ovary (CHO) cells under hypoxic condition
1997
Proliferation of multipotent hematopoietic cells controlled by a truncated erythropoietin receptor transgene.
1996 StandoutNobel
Erythropoietin receptors on murine erythroid colony-forming units: natural history
1989
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
The extended box 2 subdomain of erythropoietin receptor is nonessential for Jak2 activation yet critical for efficient mitogenesis in FDC-ER cells
1994
Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family.
1991 StandoutNobel
Embryonal Carcinoma P19 Cells Produce Erythropoietin Constitutively But Express Lactate Dehydrogenase in an Oxygen-Dependent Manner
1998 StandoutNobel
Regulation of Erythropoietin Production: New Insights Into Molecular Mechanisms of Oxygen Homeostasis
1994 StandoutNobel
The gene for the human erythropoietin receptor: analysis of the coding sequence and assignment to chromosome 19p
1990
Anaemia and resistance to malaria in transgenic mice expressing human tumour necrosis factor.
1994
Hypoxia. 5. Hypoxia and hematopoiesis
2011
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
2009 StandoutNobel
Cytokine-mediated regulation of iron transport in human monocytic cells
2003
Induction of Tyrosine Phosphorylation by the Erythropoietin Receptor Correlates with Mitogenesis
1991
The Prolactin Receptor Rescues EpoR−/− Erythroid Progenitors and Replaces EpoR in a Synergistic Interaction With c-kit
1998
Prediction of response to erythropoietin treatment in chronic anemia of cancer [see comments]
1994
Erythropoietin induces the tyrosine phosphorylation of its own receptor in human erythropoietin-responsive cells.
1992
Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin.
1994
Defective iron supply for erythropoiesis and adequate endogenous erythropoietin production in the anemia associated with systemic-onset juvenile chronic arthritis
1996
Survival or death of individual proerythroblasts results from differing erythropoietin sensitivities: a mechanism for controlled rates of erythrocyte production
1993
Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein.
1996 StandoutNobel
Role of IL-10 for Induction of Anemia During Inflammation
2002
Inhibition of in vitro erythropoiesis by soluble mediators in Plasmodium chabaudi AS malaria: lack of a major role for interleukin 1, tumor necrosis factor alpha, and gamma interferon
1994
Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer.
1994 StandoutNobel
Iron and the anemia of chronic disease.
2002
Human erythropoietin receptor: cloning, expression, and biologic characterization
1990
Erythropoietin, iron, and erythropoiesis.
2000
Chimeric tumor necrosis factor receptors with constitutive signaling activity.
1995 StandoutNobel
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
1997 StandoutNobel
Structure of the murine erythropoietin receptor complex. Characterization of the erythropoietin cross-linked proteins.
1991
Solution-phase combinatorial synthesis: Convergent multiplication of diversity via the olefin metathesis reaction
1998
Erythropoietin, iron, and erythropoiesis
2000
Ligand binding properties of the human erythropoietin receptor extracellular domain expressed in Escherichia coli.
1992
Retroviral transfer of the recombinant human erythropoietin receptor gene into single hematopoietic stem/progenitor cells from human cord blood increases the number of erythropoietin-dependent erythroid colonies
1996
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization
2003
Activation of Vascular Endothelial Growth Factor Gene Transcription by Hypoxia-Inducible Factor 1
1996 StandoutNobel
A novel site of erythropoietin production. Oxygen-dependent production in cultured rat astrocytes.
1994
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Convergent Chemical Synthesis of [Lysine24, 38, 83] Human Erythropoietin
2011
Interferon γ Downregulates Stem Cell Factor and Erythropoietin Receptors But Not Insulin-Like Growth Factor-I Receptors in Human Erythroid Colony-Forming Cells
1997
Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia.
1993 StandoutNobel
The Gene for Erythropoietin Receptor Is Expressed in Multipotential Hematopoietic and Embryonal Stem Cells: Evidence for Differentiation Stage-Specific Regulation
1992
Expression of Bcl-x in Erythroid Precursors from Patients with Polycythemia Vera
1998
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
Activation and Inhibition of Erythropoietin Receptor Function: Role of Receptor Dimerization
1994
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
Works of SB Krantz being referenced
Progress in understanding the pathogenesis of the anemia of chronic disease [see comments]
1992
Differentiation and erythropoietin receptor gene expression in human erythroid progenitor cells [see comments]
1992
Effects of recombinant erythropoietin on the concentration and cycling status of human marrow hematopoietic progenitor cells in vivo
1988
Receptors for erythropoietin in mouse and human erythroid cells and placenta
1989
Receptors for erythropoietin in mouse and human erythroid cells and placenta
1989
Inhibition of human erythroid colony-forming units by gamma interferon can be corrected by recombinant human erythropoietin [see comments]
1991
Differentiation and erythropoietin receptor gene expression in human erythroid progenitor cells [see comments]
1992
Abundance and stability of erythropoietin receptor mRNA in mouse erythroid progenitor cells
1991
Inhibition of human erythroid colony-forming units by gamma interferon can be corrected by recombinant human erythropoietin [see comments]
1991
Isolation of erythropoietin-sensitive cells from Friend virus-infected marrow cultures: characteristics of the erythropoietin response
1983
Erythropoietin
1991 Standout
Progress in understanding the pathogenesis of the anemia of chronic disease [see comments]
1992
Pharmacologic doses of recombinant human erythropoietin in the treatment of myelodysplastic syndromes [see comments]
1991
Stem cell factor retards differentiation of normal human erythroid progenitor cells while stimulating proliferation
1995
Polycythemia vera. II. Hypersensitivity of bone marrow erythroid, granulocyte-macrophage, and megakaryocyte progenitor cells to interleukin-3 and granulocyte-macrophage colony-stimulating factor
1992
Human burst-forming units-erythroid need direct interaction with stem cell factor for further development
1991
Abundance and stability of erythropoietin receptor mRNA in mouse erythroid progenitor cells
1991
Pharmacologic doses of recombinant human erythropoietin in the treatment of myelodysplastic syndromes [see comments]
1991