Citation Impact
Citing Papers
Tryptophan 7-Halogenase (PrnA) Structure Suggests a Mechanism for Regioselective Chlorination
2005 Science
An exosome-based secretion pathway is responsible for protein export from Leishmania and communication with macrophages
2010
Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR)
2010 StandoutNobel
Cancer Exosomes Trigger Fibroblast to Myofibroblast Differentiation
2010
Broad role for YBX1 in defining the small noncoding RNA composition of exosomes
2017 Nobel
Extracellular vesicles and viruses: Are they close relatives?
2016
Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes
2018 StandoutScience
Tumor-Associated MICA Is Shed by ADAM Proteases
2008
Src family kinases engage differential pathways for encapsulation into extracellular vesicles
2023
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Potential role of HER2‐overexpressing exosomes in countering trastuzumab‐based therapy
2011
Detection of phosphatidylserine-positive exosomes for the diagnosis of early-stage malignancies
2017
Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4
2015 StandoutNobel
Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters
2015
Stability of person-specific blood-based infrared molecular fingerprints opens up prospects for health monitoring
2021 StandoutNobel
Exosome-delivered EGFR regulates liver microenvironment to promote gastric cancer liver metastasis
2017
Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C–H activation
2016
Two Distinct Populations of Exosomes Are Released from LIM1863 Colon Carcinoma Cell-derived Organoids
2012
Essential role of Notch signaling in apoptosis of human pancreatic tumoral cells mediated by exosomal nanoparticles
2009
Mutant Copper-Zinc Superoxide Dismutase (SOD1) Induces Protein Secretion Pathway Alterations and Exosome Release in Astrocytes
2013
A cell-free platform for the prenylation of natural products and application to cannabinoid production
2019 StandoutNobel
Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions
2024 StandoutNobel
Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity
2013
New Insights into the Mechanism of Enzymatic Chlorination of Tryptophan
2008
An Update on in Vivo Imaging of Extracellular Vesicles as Drug Delivery Vehicles
2018
Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment
2015
Flavoprotein monooxygenases, a diverse class of oxidative biocatalysts
2006
Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer
2009
Enantioselective Intramolecular CH Amination Catalyzed by Engineered Cytochrome P450 Enzymes In Vitro and In Vivo
2013 StandoutNobel
Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells
2012
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
HIV-1 and microvesicles from T cells share a common glycome, arguing for a common origin
2009
Exosomes: immune properties and potential clinical implementations
2010
Exosomes/microvesicles: mediators of cancer-associated immunosuppressive microenvironments
2011
Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis
2016
Exosomes and Autophagy: Coordinated Mechanisms for the Maintenance of Cellular Fitness
2014
High‐Throughput Screening for Terpene‐Synthase‐Cyclization Activity and Directed Evolution of a Terpene Synthase
2013 StandoutNobel
Phase I Clinical Trial of Autologous Ascites-derived Exosomes Combined With GM-CSF for Colorectal Cancer
2008
Exosomes in the Diseased Brain: First Insights from In vivo Studies
2017
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
2015 StandoutNature
Oligodendrocytes secrete exosomes containing major myelin and stress‐protective proteins: Trophic support for axons?
2007
Exosomes: proteomic insights and diagnostic potential
2009
Exosomes in the gut
2014
Microparticles of Human Atherosclerotic Plaques Enhance the Shedding of the Tumor Necrosis Factor-α Converting Enzyme/ADAM17 Substrates, Tumor Necrosis Factor and Tumor Necrosis Factor Receptor-1
2007
Survey of the year 2004 commercial optical biosensor literature
2005
Active Wnt proteins are secreted on exosomes
2012
Loading of Vesicles into Soft Amphiphilic Nanotubes using Osmosis
2015 StandoutNobel
Exosomes as new diagnostic tools in CNS diseases
2015
Exosomes Derived from M. Bovis BCG Infected Macrophages Activate Antigen-Specific CD4+ and CD8+ T Cells In Vitro and In Vivo
2008
Expanding the Enzyme Universe: Accessing Non‐Natural Reactions by Mechanism‐Guided Directed Evolution
2015 StandoutNobel
Current and future perspectives of liquid biopsies in genomics-driven oncology
2018 Standout
Crystal structure of a eukaryotic phosphate transporter
2013 Nature
Stimulating the Release of Exosomes Increases the Intercellular Transfer of Prions
2016
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Interpretation of BMP signaling in early Xenopus development
2007 StandoutNobel
Optimizing exosomal RNA isolation for RNA-Seq analyses of archival sera specimens
2018
Secreted Glioblastoma Nanovesicles Contain Intracellular Signaling Proteins and Active Ras Incorporated in a Farnesylation-dependent Manner
2016
Late Endosomal Cholesterol Accumulation Leads to Impaired Intra-Endosomal Trafficking
2007
Shedding light on the cell biology of extracellular vesicles
2018 Standout
Cellular Internalization of Exosomes Occurs Through Phagocytosis
2010
Microparticles in Cancer
2010
Ebola virus entry requires the cholesterol transporter Niemann–Pick C1
2011 StandoutNature
Terpenoid synthase structures: a so far incomplete view of complex catalysis
2012
Exosomes are an effective vaccine against congenital toxoplasmosis in mice
2009
Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury
2010 Standout
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Exosomes as intercellular signalosomes and pharmacological effectors
2011
Amphiregulin Exosomes Increase Cancer Cell Invasion
2011
Increased exosome production from tumour cell cultures using the Integra CELLine Culture System
2008
Circulating miRNAs as Biomarker in Cancer
2019
Extracellular vesicles in blood, milk and body fluids of the female and male urogenital tract and with special regard to reproduction
2016
An Integrated Phosphoproteomics Work Flow Reveals Extensive Network Regulation in Early Lysophosphatidic Acid Signaling
2010
Introduction to Extracellular Vesicles: Biogenesis, RNA Cargo Selection, Content, Release, and Uptake
2016
A comprehensive overview of exosomes as drug delivery vehicles — Endogenous nanocarriers for targeted cancer therapy
2014
Vesicle-MaNiA: extracellular vesicles in liquid biopsy and cancer
2016
Exosomes in tumor microenvironment influence cancer progression and metastasis
2013
Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions
2012
Exosomes in human semen restrict HIV-1 transmission by vaginal cells and block intravaginal replication of LP-BM5 murine AIDS virus complex
2015
Protein Targeting to Exosomes/Microvesicles by Plasma Membrane Anchors
2011
Amyloid precursor protein products concentrate in a subset of exosomes specifically endocytosed by neurons
2017
A Regioselective Tryptophan 5-Halogenase Is Involved in Pyrroindomycin Biosynthesis in Streptomyces rugosporus LL-42D005
2005
TGFβ in Cancer
2008 Standout
Enzymatic functionalization of carbon–hydrogen bonds
2010 StandoutNobel
The Origin and Functions of Exosomes in Cancer
2018
Extracellular vesicles – Their role in the packaging and spread of misfolded proteins associated with neurodegenerative diseases
2015
Communication by Extracellular Vesicles: Where We Are and Where We Need to Go
2016 Standout
Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells
2011
Survey of the year 2003 commercial optical biosensor literature
2004
Nucleic acid amphiphiles: synthesis and self-assembled nanostructures
2011
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
The IL-6 feed-forward loop: A driver of tumorigenesis
2014
Secretion of active membrane type 1 matrix metalloproteinase (MMP‐14) into extracellular space in microvesicular exosomes
2008
NovQ is a prenyltransferase capable of catalyzing the addition of a dimethylallyl group to both phenylpropanoids and flavonoids
2009
Classification, Functions, and Clinical Relevance of Extracellular Vesicles
2012 Standout
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Cooperative Assembly of TGF-β Superfamily Signaling Complexes Is Mediated by Two Disparate Mechanisms and Distinct Modes of Receptor Binding
2008
Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor
2014
Exosomal Secretion of Cytoplasmic Prostate Cancer Xenograft-derived Proteins
2009
Monooxygenases as biocatalysts: Classification, mechanistic aspects and biotechnological applications
2010
Exosomes as Diagnostic Biomarkers in Cardiovascular Diseases
2017
Autophagy regulates exosomal release of prions in neuronal cells
2018
Enrichment of prion protein in exosomes derived from ovine cerebral spinal fluid
2008
Differential miRNA expression profile and proteome in plasma exosomes from patients with paroxysmal nocturnal hemoglobinuria
2019
Reassessment of Exosome Composition
2019 Standout
Engineered Exosomes as Vehicles for Biologically Active Proteins
2017
RNA delivery by extracellular vesicles in mammalian cells and its applications
2020
Quantitative and qualitative flow cytometric analysis of nanosized cell-derived membrane vesicles
2011
Chemokines, cytokines and exosomes help tumors to shape inflammatory microenvironment
2016
Halogenation Strategies In Natural Product Biosynthesis
2008
Cell-Produced α-Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival
2010
Genetically Engineered Microvesicles Carrying Suicide mRNA/Protein Inhibit Schwannoma Tumor Growth
2012
RhoA triggers a specific signaling pathway that generates transforming microvesicles in cancer cells
2012
Stem cell-derived polarized hepatocytes
2020 StandoutNobel
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Fluorescent labeling of nano-sized vesicles released by cells and subsequent quantitative and qualitative analysis by high-resolution flow cytometry
2012
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
Proteolipidic Composition of Exosomes Changes during Reticulocyte Maturation
2011
Exosomes, an Unmasked Culprit in Neurodegenerative Diseases
2017
Exosomes in Cancer Liquid Biopsy: A Focus on Breast Cancer
2017
The molecular architecture of protein–protein binding sites
2007
Exosome Biogenesis and Biological Function in Response to Viral Infections
2018
Biogenesis and function of extracellular vesicles in cancer
2018
Vancomycin Assembly: Nature's Way
2003
The tetraspanins CD151 and Tspan8 are essential exosome components for the crosstalk between cancer initiating cells and their surrounding
2014
New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes
2010
Extracellular vesicles: Exosomes, microvesicles, and friends
2013 Standout
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
2010 StandoutNobel
Dynamic Biodistribution of Extracellular Vesicles in Vivo Using a Multimodal Imaging Reporter
2014
Encapsulating Cas9 into extracellular vesicles by protein myristoylation
2022
Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
2016 Standout
Flavin-dependent halogenases involved in secondary metabolism in bacteria
2006
Identification of an inhibitory budding signal that blocks the release of HIV particles and exosome/microvesicle proteins
2011
Regiospecific Chlorination of (S)-β-Tyrosyl-S-Carrier Protein Catalyzed by SgcC3 in the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027
2007
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Microvesicles: mediators of extracellular communication during cancer progression
2010
Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
2015
SyrB2 in syringomycin E biosynthesis is a nonheme Fe II α-ketoglutarate- and O 2 -dependent halogenase
2005
The cis-acting signals that target proteins to exosomes and microvesicles
2013
Routes and mechanisms of extracellular vesicle uptake
2014 Standout
Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer
2011
Focus on Extracellular Vesicles: Introducing the Next Small Big Thing
2016
Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting
2015
Extracellular vesicles including exosomes are mediators of signal transduction: Are they protective or pathogenic?
2014
Biohalogenation: Nature’s Way to Synthesize Halogenated Metabolites
2009
Exosomes as new players in metabolic organ cross‐talk
2017
Sampling the Antibiotic Resistome
2006 StandoutScience
Identification and characterization of EGF receptor in individual exosomes by fluorescence‐activated vesicle sorting
2016
Human tumor virus utilizes exosomes for intercellular communication
2010
Proteomic Analysis of Two Types of Exosomes in Human Whole Saliva
2011
Extracellular Vesicles Isolated from the Leaf Apoplast Carry Stress-Response Proteins
2016
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
Unlocking Reactivity of TrpB: A General Biocatalytic Platform for Synthesis of Tryptophan Analogues
2017 StandoutNobel
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
The biology and function of exosomes in cancer
2016
Emerging applications of exosomes in cancer therapeutics and diagnostics
2017
Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and exosomes
2013
The Chemistry and Biochemistry of Vanadium and the Biological Activities Exerted by Vanadium Compounds
2004 Standout
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
The role of extracellular vesicles in neurodegenerative diseases
2016
Distinct Entry Mechanisms for Nonenveloped and Quasi-Enveloped Hepatitis E Viruses
2016
Ultrafast Dynamics of Flavins in Five Redox States
2008 StandoutNobel
The ADAMs: signalling scissors in the tumour microenvironment
2008
SPECIFICITY AND VERSATILITY IN TGF-β SIGNALING THROUGH SMADS
2005 Standout
A Panel of TrpB Biocatalysts Derived from Tryptophan Synthase through the Transfer of Mutations that Mimic Allosteric Activation
2016 StandoutNobel
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
Disulfonimide-Catalyzed Asymmetric Synthesis of β3-Amino Esters Directly from N-Boc-Amino Sulfones
2013 StandoutNobel
Membrane Vesicle Release in Bacteria, Eukaryotes, and Archaea: a Conserved yet Underappreciated Aspect of Microbial Life
2012
Nature's Inventory of Halogenation Catalysts: Oxidative Strategies Predominate
2006
An Unusual Flavin-Dependent Halogenase from the Metagenome of the Marine Sponge Theonella swinhoei WA
2017
Exosomal miRNAs as cancer biomarkers and therapeutic targets
2016
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms
2014
Characterization of exosome‐like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense
2009
Exosomal miRNAs as novel cancer biomarkers: Challenges and opportunities
2018
Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue
2015
Comparative analysis of discrete exosome fractions obtained by differential centrifugation
2014
Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics
2018 StandoutNobel
Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse
2017
Microvesicles and Viral Infection
2011
Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides
2020 StandoutNobel
Works of Sascha Keller being referenced
Body Fluid Exosomes Promote Secretion of Inflammatory Cytokines in Monocytic Cells via Toll-like Receptor Signaling
2013
Interaction and uptake of exosomes by ovarian cancer cells
2011
Functional role of N-glycosylation from ADAM10 in processing, localization and activity of the enzyme
2008
Crystallization and preliminary X-ray analysis of the aromatic prenyltransferase CloQ from the clorobiocin biosynthetic cluster ofStreptomyces roseochromogenes
2006
Body fluid derived exosomes as a novel template for clinical diagnostics
2011
Molecular replacement in the `twilight zone': structure determination of the non-haem iron oxygenase NovR fromStreptomyces spheroidesthrough repeated density modification of a poor molecular-replacement solution
2006
Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage
2011
Exosomes: From biogenesis and secretion to biological function
2006
Enzymatic Halogenation Catalyzed via a Catalytic Triad and by Oxidoreductases
2000
Malignant ascites-derived exosomes of ovarian carcinoma patients contain CD24 and EpCAM
2007
Evidence for secretion of Cu,Zn superoxide dismutase via exosomes from a cell model of amyotrophic lateral sclerosis
2007
Structure and Mechanism of the Magnesium-Independent Aromatic Prenyltransferase CloQ from the Clorobiocin Biosynthetic Pathway
2010
Extracellular Vesicle-Mediated Transfer of Genetic Information between the Hematopoietic System and the Brain in Response to Inflammation
2014
Generation of novel, secreted epidermal growth factor receptor (EGFR/ErbB1) isoforms via metalloprotease‐dependent ectodomain shedding and exosome secretion
2007
Molecular recognition of BMP-2 and BMP receptor IA
2004
Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes
2009
DNA Polymerase-Catalyzed DNA Network Growth
2008
A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44
2006
Purification and Partial Characterization of Tryptophan 7-Halogenase (PrnA) fromPseudomonas fluorescens
2000
Reinigung und teilweise Charakterisierung der Tryptophan-7-Halogenase (PrnA) ausPseudomonas fluorescens
2000