Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts
2010 StandoutNobel
Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor
2010
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
2005 StandoutScience
Cancer Regression in Patients After Transfer of Genetically Engineered Lymphocytes
2006 StandoutScience
Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
Treatment of Advanced Leukemia in Mice with mRNA Engineered T Cells
2011
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy
2022 StandoutNobel
Integrating HDAd5/35++ Vectors as a New Platform for HSC Gene Therapy of Hemoglobinopathies
2018
Oncology Meets Immunology: The Cancer-Immunity Cycle
2013 Standout
Cancer nanomedicine: progress, challenges and opportunities
2016 Standout
Increased Diels-Alderase activity through backbone remodeling guided by Foldit players
2012 StandoutNobel
Adoptive T cell therapy for cancer in the clinic
2007
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
Innate and adaptive immune cells in the tumor microenvironment
2013 Standout
Multi-input chemical control of protein dimerization for programming graded cellular responses
2019 StandoutNobel
Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells
2022 StandoutNobel
T-cell-receptor gene therapy
2002
Adoptive T Cell Transfer for Cancer Immunotherapy in the Era of Synthetic Biology
2013
Functional type 1 regulatory T cells develop regardless of FOXP3 mutations in patients with IPEX syndrome
2011
Immunotherapy of Hematologic Malignancy
2003
Reporter gene imaging: potential impact on therapy
2005
Socializing with the Neighbors
2004 Standout
CD1d expression on B-precursor acute lymphoblastic leukemia subsets with poor prognosis
2005
Computational Design of High-Affinity Epitope Scaffolds by Backbone Grafting of a Linear Epitope
2011 StandoutNobel
Targeting tumours with genetically enhanced T lymphocytes
2003
Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia
2011 Standout
CD1d is expressed on B‐chronic lymphocytic leukemia cells and mediates α‐galactosylceramide presentation to natural killer T lymphocytes
2004
Quantitatively different red cell/nucleated cell chimerism in patients with long-term, persistent hematopoietic mixed chimerism after bone marrow transplantation for thalassemia major or sickle cell disease
2010
Human anti-HIV-1 tat sFv intrabodies for gene therapy of advanced HIV-1-infection and AIDS
1999
Optimization of the In-Silico-Designed Kemp Eliminase KE70 by Computational Design and Directed Evolution
2011 StandoutNobel
The full spectrum of human naive T cells
2018
Hotspot-Centric De Novo Design of Protein Binders
2011 StandoutNobel
Hematopoietic Stem-Cell Transplantation
2006 Standout
The effect of substrate binding on the conformation and structural stability of Herpes simplex virus type 1 thymidine kinase
2001
Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy
2011
Improved Modeling of Side-Chain–Base Interactions and Plasticity in Protein–DNA Interface Design
2012 StandoutNobel
Repertoire Enhancement with Adoptively Transferred Female Lymphocytes Controls the Growth of Pre-Implanted Murine Prostate Cancer
2012 StandoutNobel
Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer
2013 Standout
JAK2, complemented by a second signal from c-kit or flt-3, triggers extensive self-renewal of primary multipotential hemopoietic cells
2002
Targeting Immunosupportive Cancer Therapies: Accentuate the Positive, Eliminate the Negative
2007 StandoutNobel
Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia
2004
Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
2014 Standout
Computational design of orthogonal nucleoside kinases
2010 StandoutNobel
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes
2016 StandoutNobel
Improving the safety of cell therapy products by suicide gene transfer
2014
Gene therapy returns to centre stage
2015 Nature
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
2005 StandoutNature
A guide to cancer immunotherapy: from T cell basic science to clinical practice
2020 Standout
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells
2013
Scientific Benchmarks for Guiding Macromolecular Energy Function Improvement
2013 StandoutNobel
Inhibition of Papillomavirus Protein Function in Cervical Cancer Cells by Intrabody Targeting
2005 StandoutNobel
Mining Endonuclease Cleavage Determinants in Genomic Sequence Data
2011 StandoutNobel
Safe and Effective In Vivo Targeting and Gene Editing in Hematopoietic Stem Cells: Strategies for Accelerating Development
2021 StandoutNobel
Regimen-Specific Effects of RNA-Modified Chimeric Antigen Receptor T Cells in Mice with Advanced Leukemia
2013
Self-Assembly of “S-Bilayers”, a Step Toward Expanding the Dimensionality of S-Layer Assemblies
2013 StandoutNobel
Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells
2006
Chimeric NK-receptor–bearing T cells mediate antitumor immunotherapy
2005
SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade
2008 StandoutNobel
Adoptive immunotherapy with genetically modified lymphocytes in allogeneic stem cell transplantation
2013
The development of imatinib as a therapeutic agent for chronic myeloid leukemia
2004
Adoptive cell transfer as personalized immunotherapy for human cancer
2015 StandoutScience
Chemically Controlled Protein Assembly: Techniques and Applications
2010
Advances in Transition Metal (Pd,Ni,Fe)-Catalyzed Cross-Coupling Reactions Using Alkyl-organometallics as Reaction Partners
2011 Standout
Strategies for enzyme/prodrug cancer therapy.
2001
Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia
2015
Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma
2008 StandoutNobel
Lack of specific γ-retroviral vector long terminal repeat promoter silencing in patients receiving genetically engineered lymphocytes and activation upon lymphocyte restimulation
2009
Graft-versus-leukemia effects of transplantation and donor lymphocytes
2008
Cytokine Storm
2020 Standout
CRISPR-enhanced engineering of therapy-sensitive cancer cells for self-targeting of primary and metastatic tumors
2018
BCR-ABL mRNA levels at and after the time of a complete cytogenetic response (CCR) predict the duration of CCR in imatinib mesylate–treated patients with CML
2006
Chimeric Antigen Receptor Therapy
2018 Standout
Going viral: chimeric antigen receptor T‐cell therapy for hematological malignancies
2014
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
Regulatory roles of IL-10–producing human follicular T cells
2019 StandoutNobel
Antigen-Specific Cytotoxicity by Invariant NKT Cells In Vivo Is CD95/CD178-Dependent and Is Correlated with Antigenic Potency
2010 StandoutNobel
CAR T cell immunotherapy for human cancer
2018 StandoutScience
CD28 costimulation and immunoaffinity-based selection efficiently generate primary gene-modified T cells for adoptive immunotherapy
2002
Systemic Activation of NRF2 Alleviates Lethal Autoimmune Inflammation in Scurfy Mice
2017 StandoutNobel
RosettaRemodel: A Generalized Framework for Flexible Backbone Protein Design
2011 StandoutNobel
Computational design of a red fluorophore ligase for site-specific protein labeling in living cells
2014 StandoutNobel
Construction and Validation of Improved Triple Fusion Reporter Gene Vectors for Molecular Imaging of Living Subjects
2007 StandoutNobel
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of Sarah Marktel being referenced
Hematopoietic stem cell function in β-thalassemia is impaired and is rescued by targeting the bone marrow niche
2020
Survival of patients with chronic-phase chronic myeloid leukaemia on imatinib after failure on interferon alfa
2003
Type 1 regulatory T cells are associated with persistent split erythroid/lymphoid chimerism after allogeneic hematopoietic stem cell transplantation for thalassemia
2009
Bone marrow stromal cells from β-thalassemia patients have impaired hematopoietic supportive capacity
2019
Management of chronic myeloid leukaemia in relapse following donor lymphocyte infusion induced remission: a retrospective study of the clinical trials committee of the British Society of Blood & Marrow Transplantation (BSBMT)
2005
Prognostic factors for patients with chronic myeloid leukaemia in chronic phase treated with imatinib mesylate after failure of interferon alfa
2003
Herpes Simplex Virus Thymidine Kinase Gene Transfer for Controlled Graft-versus-Host Disease and Graft-versus-Leukemia: Clinical Follow-up and Improved New Vectors
1998
Improving the safety of cell therapy with the TK-suicide gene
2015
Immunologic potential of donor lymphocytes expressing a suicide gene for early immune reconstitution after hematopoietic T-cell–depleted stem cell transplantation
2003
The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies
2007
Generation of human memory stem T cells after haploidentical T-replete hematopoietic stem cell transplantation
2015
Correction of β‐thalassemia major by gene transfer in haematopoietic progenitors of pediatric patients
2010
A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease
2001
Imatinib mesylate (STI571) in the treatment of relapse of chronic myeloid leukemia after allogeneic stem cell transplantation
2002
Chronic myeloid leukemia in chronic phase responding to imatinib: the occurrence of additional cytogenetic abnormalities predicts disease progression.
2003
Antitumor effects of HSV-TK–engineered donor lymphocytes after allogeneic stem-cell transplantation
2007