Citation Impact
Citing Papers
Local circadian clock gates cell cycle progression of transient amplifying cells during regenerative hair cycling
2013
Interfollicular Epidermal Stem Cells Self-Renew via Autocrine Wnt Signaling
2013 Science
Defining the Epithelial Stem Cell Niche in Skin
2003 StandoutScience
Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin
2010 Science
NONO couples the circadian clock to the cell cycle
2012
Mitotic and mitogenic Wnt signalling
2012
Canonical notch signaling functions as a commitment switch in the epidermal lineage
2006
Distinct fibroblast lineages determine dermal architecture in skin development and repair
2013 StandoutNature
Cutaneous cancer stem cell maintenance is dependent on β-catenin signalling
2008 Nature
β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin
2001 Standout
Epidermal Notch signalling: differentiation, cancer and adhesion
2008
Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds
2019
DKK1 Antagonizes Wnt Signaling without Promotion of LRP6 Internalization and Degradation
2008
Inference and analysis of cell-cell communication using CellChat
2021 Standout
mTOR Mediates Wnt-Induced Epidermal Stem Cell Exhaustion and Aging
2009
Wnt/β-catenin signaling in dermal condensates is required for hair follicle formation
2013
How Fission Yeast Fission in the Middle
1996 StandoutNobel
Epidermal homeostasis: a balancing act of stem cells in the skin
2009 Standout
A Signaling Pathway Involving TGF-β2 and Snail in Hair Follicle Morphogenesis
2004
Transcripts of one of two Drosophila cyclin genes become localized in pole cells during embryogenesis
1989 Nature
Generation of Human Melanocytes from Induced Pluripotent Stem Cells
2011 StandoutNobel
Circular RNAs are a large class of animal RNAs with regulatory potency
2013 StandoutNature
Epithelial Stem Cells: Turning over New Leaves
2007
Hierarchical patterning modes orchestrate hair follicle morphogenesis
2017
The microenvironment of the embryonic neural stem cell: Lessons from adult niches?
2007
Epigenetic regulation of aging stem cells
2011
Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
2004 Standout
Hair cycle regulation of Hedgehog signal reception
2003
Modulation of BMP Signaling by Noggin is Required for Induction of the Secondary (Nontylotrich) Hair Follicles
2002
miR-203 represses ‘stemness’ by repressing ΔNp63
2008
Mutations in AXIN2 Cause Familial Tooth Agenesis and Predispose to Colorectal Cancer
2004
Melanocytes in Development, Regeneration, and Cancer
2008
Regulatory T Cells
2000 StandoutNobel
Wound repair and regeneration
2008 StandoutNature
NFATc1 Balances Quiescence and Proliferation of Skin Stem Cells
2008
Links between signal transduction, transcription and adhesion in epithelial bud development
2003 Nature
Elite and stochastic models for induced pluripotent stem cell generation
2009 StandoutNatureNobel
Embryonic stem cell–specific microRNAs promote induced pluripotency
2009
Leucine-Rich Repeat-Containing G-Protein-Coupled Receptors as Markers of Adult Stem Cells
2010
Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin
2001
Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication
1990 StandoutNobel
Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells
2001
Lgr5-Expressing Cells Are Sufficient and Necessary for Postnatal Mammary Gland Organogenesis
2013
A biochemical function for attractin in agouti-induced pigmentation and obesity
2001
Wnt Proteins Are Self-Renewal Factors for Mammary Stem Cells and Promote Their Long-Term Expansion in Culture
2010
Fgf20 governs formation of primary and secondary dermal condensations in developing hair follicles
2013
Modulation of murine melanocyte function invitro by agouti signal protein
1997
Staufen protein associates with the 3′UTR of bicoid mRNA to form particles that move in a microtubule-dependent manner
1994 StandoutNobel
The origin of pattern and polarity in the Drosophila embryo
1992 StandoutNobel
Defining the impact of β-catenin/Tcf transactivation on epithelial stem cells
2005
Autoimmune ovarian disease: mechanism of disease induction and prevention
1997
Key Roles for Transforming Growth Factor β in Melanocyte Stem Cell Maintenance
2010
A skin microRNA promotes differentiation by repressing ‘stemness’
2008 Nature
Developmental Stage and Time Dictate the Fate of Wnt/β-Catenin-Responsive Stem Cells in the Mammary Gland
2012
The puff-specific Drosophila protein Bj6, encoded by the gene no-on transient A, shows homology to RNA-binding proteins
1990
Therapeutic implications of cancer stem cells
2003
The Regulatory Basis of Melanogenic Switching
2002
WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis
2009
KLF4, p21 and context-dependent opposing forces in cancer
2005
Dermal Condensate Niche Fate Specification Occurs Prior to Formation and Is Placode Progenitor Dependent
2018
MITF: master regulator of melanocyte development and melanoma oncogene
2006
Long-Term In Vitro Expansion of Salivary Gland Stem Cells Driven by Wnt Signals
2015
Single-Cell Analysis Reveals a Hair Follicle Dermal Niche Molecular Differentiation Trajectory that Begins Prior to Morphogenesis
2018
Wnt/β-Catenin Signaling and Disease
2012 Standout
p21 in cancer: intricate networks and multiple activities
2009 Standout
Epidermal Wnt Controls Hair Follicle Induction by Orchestrating Dynamic Signaling Crosstalk between the Epidermis and Dermis
2012
Choreographing Immunity in the Skin Epithelial Barrier
2019
Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing
2020
Getting under the skin of epidermal morphogenesis
2002
Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle Development
2020
Cyclin is a component of maturation-promoting factor from Xenopus
1990 StandoutNobel
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
2003 Standout
Mutation in WNT10A Is Associated with an Autosomal Recessive Ectodermal Dysplasia: The Odonto-onycho-dermal Dysplasia
2007
Epidermal stem cells: practical perspectives and potential uses
2009
Fate of Melanocytes During Development of the Hair Follicle Pigmentary Unit
2003
Stem cells in the skin: waste not, Wnt not
2003
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression
2007 StandoutNobel
Capturing and profiling adult hair follicle stem cells
2004 Standout
Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration
2008 Nature
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
bottleneck acts as a regulator of the microfilament network governing cellularization of the Drosophila embryo
1993 StandoutNobel
Sox9 Is Essential for Outer Root Sheath Differentiation and the Formation of the Hair Stem Cell Compartment
2005
A dermal niche for multipotent adult skin-derived precursor cells
2004
CDK Inhibitors: Cell Cycle Regulators and Beyond
2008
A Tripartite Protein Complex with the Potential to Couple Synaptic Vesicle Exocytosis to Cell Adhesion in Brain
1998 StandoutNobel
Transient activation of β-catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice
2003
APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex
2010 Nature
GATA-3: an unexpected regulator of cell lineage determination in skin
2003
The Hallmarks of Aging
2013 Standout
CDC5 and CKII Control Adaptation to the Yeast DNA Damage Checkpoint
1997 StandoutNobel
Fas and c-kit are Involved in the Control of Hair Follicle Melanocyte Apoptosis and Migration in Chemotherapy-Induced Hair Loss
2003
Wnt activation in nail epithelium couples nail growth to digit regeneration
2013 Nature
MYC in mammalian epidermis: how can an oncogene stimulate differentiation?
2008
Functions of the Peroxisome Proliferator-Activated Receptor (PPAR) α and β in Skin Homeostasis, Epithelial Repair, and Morphogenesis
2006
Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle
2005
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
2009 StandoutNature
β-Catenin and Hedgehog Signal Strength Can Specify Number and Location of Hair Follicles in Adult Epidermis without Recruitment of Bulge Stem Cells
2005
Canonical Wnt signals are essential for homeostasis of the intestinal epithelium
2003
In search of the “hair cycle clock”: a guided tour
2004
Regulation of Yellow Pigment Formation in Mice: A Historical Perspective
2003
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
γ-Secretase Functions through Notch Signaling to Maintain Skin Appendages but Is Not Required for Their Patterning or Initial Morphogenesis
2004
Cancer stem cells and human malignant melanoma
2008
BMP signaling in dermal papilla cells is required for their hair follicle-inductive properties
2008
Universal control mechanism regulating onset of M-phase
1990 StandoutNatureNobel
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA
2003
Axin2 marks quiescent hair follicle bulge stem cells that are maintained by autocrine Wnt/β-catenin signaling
2016
Tumour stem cells and drug resistance
2005 Standout
KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin
2009
Checkpoints: Controls That Ensure the Order of Cell Cycle Events
1989 StandoutScienceNobel
Functional Elements of the Cytoskeleton in the Early Drosophila Embryo
1993 StandoutNobel
Advances in skin grafting and treatment of cutaneous wounds
2014 StandoutScience
Apical junctions and cell signalling in epithelia
1993
WNT and DKK Determine Hair Follicle Spacing Through a Reaction-Diffusion Mechanism
2006 Science
Lgr5-EGFP Marks Taste Bud Stem/Progenitor Cells in Posterior Tongue
2013
Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals
2005
Epidermal Stem Cells of the Skin
2006
Transient activation of β-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours
2004
The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cells
2004
Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero
1998 StandoutNobel
Specification of osteoblast cell fate by canonical Wnt signaling requires Bmp2
2016
Bone Morphogenetic Protein Signaling Inhibits Hair Follicle Anagen Induction by Restricting Epithelial Stem/Progenitor Cell Activation and Expansion
2006
G Protein-Coupled Receptors: Functional and Mechanistic Insights Through Altered Gene Expression
1998 StandoutNobel
An updated classification of hair follicle morphogenesis
2019
The extracellular matrix geneFrem1is essential for the normal adhesion of the embryonic epidermis
2004 StandoutNobel
Keratinocyte Stem Cells: a Commentary1
2002
Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling
2007
The conserved Schizosaccharomyces pombe kinase plo1, required to form a bipolar spindle, the actin ring, and septum, can drive septum formation in G1 and G2 cells.
1995
Binding of Neuroligins to PSD-95
1997 StandoutScienceNobel
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation
1999 Standout
Dermal β-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation
2012
Maternal effect mutations of the sponge locus affect actin cytoskeletal rearrangements in Drosophila melanogaster embryos.
1992 StandoutNobel
R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis
2008
Controls of Hair Follicle Cycling
2001 Standout
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Circadian Clock, Cancer, and Chemotherapy
2014 StandoutNobel
Single Lgr5- or Lgr6-expressing taste stem/progenitor cells generate taste bud cells ex vivo
2014
Cyclins A and B associate with chromatin and the polar regions of spindles, respectively, and do not undergo complete degradation at anaphase in syncytial Drosophila embryos.
1992
Lhx2 Maintains Stem Cell Character in Hair Follicles
2006 Science
Persistence of Physiological Self Antigen Is Required for the Regulation of Self Tolerance
2000
Mechanisms Regulating Epithelial Stratification
2007
The Mating of a Fly
1994 StandoutScienceNobel
Nuclear and cytoplasmic mitotic cycles continue in Drosophila embryos in which DNA synthesis is inhibited with aphidicolin.
1988
Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal
2012 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
The nullo protein is a component of the actin-myosin network that mediates cellularization in Drosophila melanogaster embryos
1994 StandoutNobel
Pleiotropic effects of the mouse lethal yellow (A y) mutation explained by deletion of a maternally expressed gene and the simultaneous production of agouti fusion RNAs
1994
The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells
2006
Mitosis
1989 Science
Tracking adult stem cells
2011
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation
2018
microRNA Functions
2007 Standout
Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome
2011
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
Immunopurification of Ago1 miRNPs selects for a distinct class of microRNA targets
2009 StandoutNobel
Plakoglobin Suppresses Epithelial Proliferation and Hair Growth in Vivo
2000 StandoutNobel
A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning
2003
Works of Sarah E. Millar being referenced
Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis
2012
Wnt/β-Catenin Signaling Regulates Postnatal Development and Regeneration of the Salivary Gland
2010
Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing
2018
p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation
2005
Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/β-catenin signaling
2008
The Mammary Bud as a Skin Appendage: Unique and Shared Aspects of Development
2006
Pax3 functions at a nodal point in melanocyte stem cell differentiation
2005 Nature
Reciprocal Requirements for EDA/EDAR/NF-κB and Wnt/β-Catenin Signaling Pathways in Hair Follicle Induction
2009
Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis
2001
Molecular Mechanisms Regulating Hair Follicle Development
2002
WNT Signals Are Required for the Initiation of Hair Follicle Development
2002 Standout
Requirement of Rac1 distinguishes follicular from interfollicular epithelial stem cells
2007
Towards a molecular understanding of hair loss and its treatment
2001
Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding
2007 Nature
Distinct Functions for Wnt/β-Catenin in Hair Follicle Stem Cell Proliferation and Survival and Interfollicular Epidermal Homeostasis
2013
WNT Signaling in the Control of Hair Growth and Structure
1999
The miRNA-Processing Enzyme Dicer Is Essential for the Morphogenesis and Maintenance of Hair Follicles
2006
Autoimmune disease of the ovary induced by a ZP3 peptide from the mouse zona pellucida.
1992
Expression of Frizzled Genes in Developing and Postnatal Hair Follicles
2004
A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases
2008
The WNT7b Promoter Is Regulated by TTF-1, GATA6, and Foxa2 in Lung Epithelium
2002
Wnt-β-catenin signaling initiates taste papilla development
2006
Wnt/β-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal–distal patterning in the lung
2005
Fgf9 from dermal γδ T cells induces hair follicle neogenesis after wounding
2013
Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis
2004
Self-Organizing and Stochastic Behaviors During the Regeneration of Hair Stem Cells
2011 Science
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation
2009
Lipid defect underlies selective skin barrier impairment of an epidermal-specific deletion of Gata-3
2006
Cloning of a gene encoding an antigen associated with the centrosome in Drosophila
1988
Activation of β-catenin signaling programs embryonic epidermis to hair follicle fate
2008
Expression and transgenic studies of the mouse agouti gene provide insight into the mechanisms by which mammalian coat color patterns are generated
1995
EpithelialBmpr1aregulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development
2004
Impaired Notch Signaling Promotes De novo Squamous Cell Carcinoma Formation
2006
The distribution of a ‘mitosis-specific’ antigen during Drosophila development
1987
LHX2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth
2016
Differences in dorsal and ventral pigmentation result from regional expression of the mouse agouti gene.
1994