Citation Impact
Citing Papers
Complement and microglia mediate early synapse loss in Alzheimer mouse models
2016 StandoutScience
Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
2011 Standout
Impaired Toll-like receptor 8–mediated IL-6 and TNF-α production in antigen-presenting cells from patients with X-linked agammaglobulinemia
2006
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
Group A Streptococcus Activates Type I Interferon Production and MyD88-dependent Signaling without Involvement of TLR2, TLR4, and TLR9
2008 StandoutNobel
MyD88 Adapter-like (Mal)/TIRAP Interaction with TRAF6 Is Critical for TLR2- and TLR4-mediated NF-κB Proinflammatory Responses
2009
IRAK1 and IRAK4 Promote Phosphorylation, Ubiquitination, and Degradation of MyD88 Adaptor-like (Mal)
2010
Dissecting negative regulation of Toll-like receptor signaling
2012
A view on drug resistance in cancer
2019 StandoutNature
Necroptosis and its role in inflammation
2015 StandoutNature
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
2010 Standout
Nonredundant roles of TIRAP and MyD88 in airway response to endotoxin, independent of TRIF, IL-1 and IL-18 pathways
2006 StandoutNobel
SOCS proteins, cytokine signalling and immune regulation
2007 Standout
When Signaling Pathways Collide: Positive and Negative Regulation of Toll-like Receptor Signal Transduction
2008
What the Myddosome structure tells us about the initiation of innate immunity
2011
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
UNC93B1 Is Essential for TLR11 Activation and IL-12-dependent Host Resistance to Toxoplasma gondii
2010
Shared Principles in NF-κB Signaling
2008 Standout
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity
2011 Standout
Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b
2010
Pattern Recognition Receptors and Inflammation
2010 Standout
Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1
2008
Severe Sepsis and Septic Shock
2013 Standout
Increased CD40 Expression Enhances Early STING-Mediated Type I Interferon Response and Host Survival in a Rodent Malaria Model
2016
TAM Receptors Are Pleiotropic Inhibitors of the Innate Immune Response
2007
Intracellular Toll-like Receptors
2010 StandoutNobel
C1q-induced LRP1B and GPR6 Proteins Expressed Early in Alzheimer Disease Mouse Models, Are Essential for the C1q-mediated Protection against Amyloid-β Neurotoxicity
2012
Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases
2008
The molecular basis of the host response to lipopolysaccharide
2009
NF-κB and the immune response
2006
MyD88-mediated stabilization of interferon-γ-induced cytokine and chemokine mRNA
2006
Toll-like receptor signalling
2004 Standout
Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer
2017 StandoutNobel
Regulatory molecules required for nucleotide‐sensing Toll‐like receptors
2008
Signal transduction by the lipopolysaccharide receptor, Toll‐like receptor‐4
2004
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
2005 StandoutNature
Mechanisms of Age-Related Macular Degeneration
2012
Immunity, Inflammation, and Cancer
2010 Standout
Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21
2009
A cell biological view of Toll-like receptor function: regulation through compartmentalization
2009
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
2015 StandoutNature
Host innate immune responses to sepsis
2013
TLR signaling
2007
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
2016 StandoutNature
Non-canonical inflammasome activation targets caspase-11
2011 StandoutNature
Development of B-lineage Predominant Lentiviral Vectors for Use in Genetic Therapies for B Cell Disorders
2010
Origin and physiological roles of inflammation
2008 StandoutNature
Mechanisms and Functions of Inflammasomes
2014 Standout
Innate immunity of the newborn: basic mechanisms and clinical correlates
2007 Standout
Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk
2011
Recognition of Hyaluronan Released in Sterile Injury Involves a Unique Receptor Complex Dependent on Toll-like Receptor 4, CD44, and MD-2
2007 StandoutNobel
Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases
2012 StandoutNobel
A Dimer of the Toll-Like Receptor 4 Cytoplasmic Domain Provides a Specific Scaffold for the Recruitment of Signalling Adaptor Proteins
2007
TIR-containing adaptors in Toll-like receptor signalling
2009
Phosphoinositide-Mediated Adaptor Recruitment Controls Toll-like Receptor Signaling
2006
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
2007 Standout
Bruton's tyrosine kinase together with PI 3-kinase are part of Toll-like receptor 2 multiprotein complex and mediate LTA induced Toll-like receptor 2 responses in macrophages
2006
Toll-Like Receptor Signaling Pathways
2014 Standout
Pathogen Recognition and Innate Immunity
2006 Standout
Mapping spatial heterogeneity in the tumor microenvironment: a new era for digital pathology
2015
Immunostimulatory Characteristics Induced by Linear Polyethyleneimine–Plasmid DNA Complexes in Cultured Macrophages
2009
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
2010 StandoutNobel
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
2016 Standout
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
Structure and Function of Toll Receptors and Their Ligands
2007
Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response
2012
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
2008 StandoutNature
Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
2005 StandoutNobel
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
2011 StandoutNobel
MicroRNA-98 and let-7 Confer Cholangiocyte Expression of Cytokine-Inducible Src Homology 2-Containing Protein in Response to Microbial Challenge
2009
Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA
2011 StandoutNobel
IFNγ-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice
2006
Intracellular Delivery of a Cell-Penetrating SOCS1 that Targets IFN-γ Signaling
2009
Modulation of three key innate immune pathways for the most common retinal degenerative diseases
2018
Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus
2014 StandoutNobel
NF-κB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1
2007
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering
2013 StandoutNobel
Regulation of Adaptive Immunity by the Innate Immune System
2010 StandoutScience
Plant and Animal Sensors of Conserved Microbial Signatures
2010 StandoutScienceNobel
Lysosome-associated small Rab GTPase Rab7b negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4
2007
Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress
2015 StandoutNobel
Signaling Pathways Downstream of Pattern-Recognition Receptors and Their Cross Talk
2007
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of Sarah Doyle being referenced
Bruton's Tyrosine Kinase Is Involved in p65-mediated Transactivation and Phosphorylation of p65 on Serine 536 during NFκB Activation by Lipopolysaccharide
2005
The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation
2012
Toll-like receptors: From the discovery of NFκB to new insights into transcriptional regulations in innate immunity
2006
Signaling by Toll-like Receptors 8 and 9 Requires Bruton's Tyrosine Kinase
2007
TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88–independent TLR4 pathway
2009
Targeting the NLRP3 inflammasome in chronic inflammatory diseases: current perspectives
2015
NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components
2012
Bruton's Tyrosine Kinase Is a Toll/Interleukin-1 Receptor Domain-binding Protein That Participates in Nuclear Factor κB Activation by Toll-like Receptor 4
2003
Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation
2006
Quantitative Image Analysis of Cellular Heterogeneity in Breast Tumors Complements Genomic Profiling
2012
TRAM Is Required for TLR2 Endosomal Signaling to Type I IFN Induction
2014
Therapeutic Targeting of Toll-Like Receptors for Infectious and Inflammatory Diseases and Cancer
2009