Citation Impact
Citing Papers
CUL7 Is a Novel Antiapoptotic Oncogene
2007
MYC Can Induce DNA Breaks In vivo and In vitro Independent of Reactive Oxygen Species
2006
Genomic and Proteomic Analysis Reveals a Threshold Level of MYC Required for Tumor Maintenance
2008
The c-Myc Oncogene Directly Induces the H19 Noncoding RNA by Allele-Specific Binding to Potentiate Tumorigenesis
2006
Genome-Wide Mapping of in Vivo Protein-DNA Interactions
2007 StandoutScience
PI3K-targeted therapy can be evaded by gene amplification along the MYC-eukaryotic translation initiation factor 4E (eIF4E) axis
2011
Drosophila dMyc is required for ovary cell growth and endoreplication
2004
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
2010 StandoutNobel
TOR Signaling in Growth and Metabolism
2006 Standout
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
2017 Standout
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
2019 Standout
Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
2010 StandoutNobel
Large‐scale survey and database of high affinity ligands for peptide recognition modules
2020
The interplay between MYC and HIF in cancer
2007
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
2009 StandoutNobel
The role of c-myc in regulation of translation initiation
2004
Ubiquitylation of the amino terminus of Myc by SCFβ-TrCP antagonizes SCFFbw7-mediated turnover
2010
Direct observation of individual endogenous protein complexes in situ by proximity ligation
2006 Standout
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
2020 Standout
MYC on the Path to Cancer
2012 Standout
A view on drug resistance in cancer
2019 StandoutNature
Pathogenic missense protein variants affect different functional pathways and proteomic features than healthy population variants
2021
Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts
2011
Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1
2011 StandoutNatureNobel
Activated eIF4E-binding Protein Slows G1 Progression and Blocks Transformation by c-myc without Inhibiting Cell Growth
2004
The Mad Side of the Max Network: Antagonizing the Function of Myc and More
2006
Small-Molecule Inhibition of c-MYC:MAX Leucine Zipper Formation Is Revealed by Ion Mobility Mass Spectrometry
2012 StandoutNobel
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
2011 StandoutNature
N and C-terminal Sub-regions in the c-Myc Transactivation Region and their Joint Role in Creating Versatility in Folding and Binding
2004
Mechanism of transcriptional activation by the Myc oncoproteins
2006
Transcription-independent functions of MYC: regulation of translation and DNA replication
2008
The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth
2007
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
A role for c-Myc in the regulation of ribosomal RNA processing
2003
The ubiquitin-specific protease USP28 is required for MYC stability
2007
A Core MYC Gene Expression Signature Is Prominent in Basal-Like Breast Cancer but Only Partially Overlaps the Core Serum Response
2009
c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression
2002
Analysis of Myc Bound Loci Identified by CpG Island Arrays Shows that Max Is Essential for Myc-Dependent Repression
2003
c-Myc-regulated microRNAs modulate E2F1 expression
2005 StandoutNature
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
The interaction between Myc and Miz1 is required to antagonize TGFβ-dependent autocrine signaling during lymphoma formation and maintenance
2010
c-Myc, Genome Instability, and Tumorigenesis: The Devil Is in the Details
2006
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
2007 StandoutNobel
Developmental Context Determines Latency of MYC-Induced Tumorigenesis
2004
A ribosomal protein L23-nucleophosmin circuit coordinates Miz1 function with cell growth
2008
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
2007 StandoutNobel
Reconstructing MYC: Figure 1.
2003
The ground state of embryonic stem cell self-renewal
2008 StandoutNature
A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells
2006 Standout
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
2006 StandoutNobel
c-Myc as a therapeutic target in cancer
2004
Functional and physical communication between oncoproteins and tumor suppressors
2005
HIF-1 Inhibits Mitochondrial Biogenesis and Cellular Respiration in VHL-Deficient Renal Cell Carcinoma by Repression of C-MYC Activity
2007 StandoutNobel
Mapping and analysis of chromatin state dynamics in nine human cell types
2011 StandoutNature
c-MYC: more than just a matter of life and death
2002
Myc Target Transcriptomes
2006
Lessons Learned from Myc/Max/Mad Knockout Mice
2006
Proteolytic Control of the Oncoprotein Transcription Factor Myc
2011
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network
2003
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
Conditional transgenic models define how MYC initiates and maintains tumorigenesis
2006
p19ARF directly and differentially controls the functions of c-Myc independently of p53
2004 Nature
The c-Myc target gene network
2006
Genomic targets of the human c-Myc protein
2003
Could MYC Induction of Mitochondrial Biogenesis be linked to ROS Production and Genomic Instability?
2005
Polycomb mediates Myc autorepression and its transcriptional control of many loci in Drosophila
2005 Nobel
The c‐myc Promoter: Still MysterY and Challenge
2007
Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice
2010
MYC as a regulator of ribosome biogenesis and protein synthesis
2010
Unbiased Mapping of Transcription Factor Binding Sites along Human Chromosomes 21 and 22 Points to Widespread Regulation of Noncoding RNAs
2004
Generation of germline-competent induced pluripotent stem cells
2007 StandoutNatureNobel
Myc/Max/Mad in Invertebrates: The Evolution of the Max Network
2006
The computational prediction of protein assemblies
2017
Cancer therapeutics: Targeting the dark side of Myc
2005
Biophysical prediction of protein–peptide interactions and signaling networks using machine learning
2020
Reflecting on 25 years with MYC
2008 Standout
Function of the c-Myc oncoprotein in chromatin remodeling and transcription
2001
WebGestalt 2017: a more comprehensive, powerful, flexible and interactive gene set enrichment analysis toolkit
2017
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Translocations involving c-myc and c-myc function
2001
Modelling Myc inhibition as a cancer therapy
2008 Nature
Genomic Binding and Transcriptional Regulation by the Drosophila Myc and Mnt Transcription Factors
2005
Analysis of genomic targets reveals complex functions of MYC
2004
Regulation of reactive oxygen species, DNA damage and c-Myc function by peroxiredoxin 1
2005
Transcriptional regulation and transformation by Myc proteins
2005
The Myc oncoprotein as a therapeutic target for human cancer
2006
Evolution and Functions of Long Noncoding RNAs
2009 Standout
The Ins and Outs of MYC Regulation by Posttranslational Mechanisms
2006
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Myc Recruits P-TEFb to Mediate the Final Step in the Transcriptional Activation of the cad Promoter
2002
Mechanisms of Transcriptional Repression by Myc
2006
FunCoup 4: new species, data, and visualization
2017
Phosphorylation by Glycogen Synthase Kinase-3 Controls c-Myc Proteolysis and Subnuclear Localization
2003
Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice
2007 StandoutNobel
Dissection of transcriptional programmes in response to serum and c-Myc in a human B-cell line
2004
c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription
2005
Identification of stem cells in small intestine and colon by marker gene Lgr5
2007 StandoutNature
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
2009 StandoutNature
The Oscar-worthy role of Myc in apoptosis
2006
Quantitative proteomic analysis of Myc oncoprotein function
2002
Combined Analysis of Murine and Human Microarrays and ChIP Analysis Reveals Genes Associated with the Ability of MYC To Maintain Tumorigenesis
2008
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
2020 Standout
Stimulation of c‐MYC transcriptional activity and acetylation by recruitment of the cofactor CBP
2003
Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment
2003
Nucleophosmin interacts directly with c-Myc and controls c-Myc-induced hyperproliferation and transformation
2008
Mapping of Protein-Protein Interactions: Web-Based Resources for Revealing Interactomes
2018
Life with Oxygen
2007 StandoutScienceNobel
Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation
2007
Myc Stimulates Nuclearly Encoded Mitochondrial Genes and Mitochondrial Biogenesis
2005
Activation of Transferrin Receptor 1 by c-Myc Enhances Cellular Proliferation and Tumorigenesis
2006
Defective double-strand DNA break repair and chromosomal translocations by MYC overexpression
2003
The world according to MYC
2007
TRRAP-Dependent and TRRAP-Independent Transcriptional Activation by Myc Family Oncoproteins
2002
Targeting MYC-Regulated miRNAs to Combat Cancer
2010
Evaluation of Myc E-Box Phylogenetic Footprints in Glycolytic Genes by Chromatin Immunoprecipitation Assays
2004
SWISS-MODEL: homology modelling of protein structures and complexes
2018 Standout
Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16 INK4a
2006
dMyc is required for larval growth and endoreplication in Drosophila
2004
Identification of Internal Ribosome Entry Segment (IRES)-trans-Acting Factors for the Myc Family of IRESs
2007
Mass spectrometry-based proteomics
2003 StandoutNature
Peptide-binding specificity prediction using fine-tuned protein structure prediction networks
2023 StandoutNobel
Mnt Takes Control as Key Regulator of the Myc/Max/Mxd Network
2007
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Global mapping of c-Myc binding sites and target gene networks in human B cells
2006
STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
2018 Standout
Network Medicine Framework for Identifying Drug Repurposing Opportunities for COVID-19
2020
c-Myc regulates cell size and ploidy but is not essential for postnatal proliferation in liver
2005
Molecular features of adult mouse small intestinal epithelial progenitors
2003
Promoter-binding and repression of PDGFRB by c-Myc are separable activities
2004
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism
2005
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet
2011 StandoutNobel
A Conserved Myc Protein Domain, MBIV, Regulates DNA Binding, Apoptosis, Transformation, and G2 Arrest
2006
The Transcriptional Repressor dMnt Is a Regulator of Growth in Drosophila melanogaster
2005
The Life Cycle of C-Myc: From Synthesis to Degradation
2004
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Myc Potentiates Apoptosis by Stimulating Bax Activity at the Mitochondria
2001
The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop
2011
Works of Sara Oster being referenced
The myc Oncogene: arvelouslomplex
2002
The BioGRID interaction database: 2017 update
2016
Identifying Genes Regulated in a Myc-dependent Manner
2002
Functional analysis of the N-terminal domain of the Myc oncoprotein
2003
Promotion of growth and apoptosis in c-myc nullizygous fibroblasts by other members of the myc oncoprotein family
2000
Myc Is an Essential Negative Regulator of Platelet-Derived Growth Factor Beta Receptor Expression
2000