Citation Impact
Citing Papers
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes
2020 StandoutNobel
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
2015 StandoutNobel
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
2016 StandoutScienceNobel
CRISPR–Cas9 Structures and Mechanisms
2017 StandoutNobel
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
RNA-Guided Human Genome Engineering via Cas9
2013 StandoutScience
The iCRISPR Platform for Rapid Genome Editing in Human Pluripotent Stem Cells
2014
CRISPR-Cas orthologues and variants: optimizing the repertoire, specificity and delivery of genome engineering tools
2017
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
The CRISPR tool kit for genome editing and beyond
2018
Precision cancer mouse models through genome editing with CRISPR-Cas9
2015
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
CRISPR-based technologies: prokaryotic defense weapons repurposed
2014
CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair
2018
High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
2016 StandoutNature
CRISPR-Cas3 induces broad and unidirectional genome editing in human cells
2019
Editing the epigenome: technologies for programmable transcription and epigenetic modulation
2016
Targeted Gene Correction of Laminopathy-Associated LMNA Mutations in Patient-Specific iPSCs
2011
Comparison of non-canonical PAMs for CRISPR/Cas9-mediated DNA cleavage in human cells
2014
Efficient and Allele-Specific Genome Editing of Disease Loci in Human iPSCs
2014
Expanding the Biologist’s Toolkit with CRISPR-Cas9
2015 StandoutNobel
Induced Pluripotent Stem Cells Meet Genome Editing
2016
Orthogonal Cas9–Cas9 chimeras provide a versatile platform for genome editing
2018
Development of an intein-mediated split–Cas9 system for gene therapy
2015
Genome-Editing Technologies: Principles and Applications
2016
Expanding the CRISPR imaging toolset withStaphylococcus aureusCas9 for simultaneous imaging of multiple genomic loci
2016
Programmable RNA Tracking in Live Cells with CRISPR/Cas9
2016 StandoutNobel
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
NmeCas9 is an intrinsically high-fidelity genome-editing platform
2018
Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy
2015
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients
2013
Defining and improving the genome-wide specificities of CRISPR–Cas9 nucleases
2016
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
2017 StandoutNatureNobel
Inhibition of CRISPR-Cas systems by mobile genetic elements
2017
The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
2016 StandoutNatureNobel
Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome
2015
The structural biology of CRISPR-Cas systems
2015 StandoutNobel
Single-Stranded DNA Cleavage by Divergent CRISPR-Cas9 Enzymes
2015 StandoutNobel
A Broad-Spectrum Inhibitor of CRISPR-Cas9
2017 StandoutNobel
Programmable RNA recognition and cleavage by CRISPR/Cas9
2014 StandoutNatureNobel
CRISPR/Cas9-Based Engineering of the Epigenome
2017
Beyond editing: repurposing CRISPR–Cas9 for precision genome regulation and interrogation
2015
Targeted activation of diverse CRISPR-Cas systems for mammalian genome editing via proximal CRISPR targeting
2017
In vivo genome editing using Staphylococcus aureus Cas9
2015 StandoutNature
Adeno-Associated Virus–Mediated Delivery of CRISPR–Cas Systems for Genome Engineering in Mammalian Cells
2016
CRISPR-Cas systems for editing, regulating and targeting genomes
2014 Standout
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
Development and Applications of CRISPR-Cas9 for Genome Engineering
2014 Standout
Conformational control of DNA target cleavage by CRISPR–Cas9
2015 StandoutNatureNobel
Increasing the specificity of CRISPR systems with engineered RNA secondary structures
2019
A thermostable Cas9 with increased lifetime in human plasma
2017 StandoutNobel
The next generation of CRISPR–Cas technologies and applications
2019
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation
2020 StandoutNobel
Genome Editing in Human Stem Cells
2014
The Hallmarks of Aging
2013 Standout
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Increasing Cytosine Base Editing Scope and Efficiency With Engineered Cas9-PmCDA1 Fusions and the Modified sgRNA in Rice
2019
Protein Engineering of Cas9 for Enhanced Function
2014
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Partial DNA-guided Cas9 enables genome editing with reduced off-target activity
2018
A Compact, High-Accuracy Cas9 with a Dinucleotide PAM for In Vivo Genome Editing
2018
DNase H Activity of Neisseria meningitidis Cas9
2015
Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System
2015 StandoutNobel
Low Incidence of Off-Target Mutations in Individual CRISPR-Cas9 and TALEN Targeted Human Stem Cell Clones Detected by Whole-Genome Sequencing
2014
RNA-dependent DNA endonuclease Cas9 of the CRISPR system: Holy Grail of genome editing?
2013
Progress and prospects in plant genome editing
2017
Continuous evolution of SpCas9 variants compatible with non-G PAMs
2020
High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells
2020
Genome-editing revolution: My whirlwind year with CRISPR
2015 StandoutNatureNobel
Delivery and Specificity of CRISPR/Cas9 Genome Editing Technologies for Human Gene Therapy
2015
The Bacterial Origins of the CRISPR Genome-Editing Revolution
2015
Genome Engineering with Targetable Nucleases
2014
A prudent path forward for genomic engineering and germline gene modification
2015 StandoutScienceNobel
A Cas9–guide RNA complex preorganized for target DNA recognition
2015 StandoutScienceNobel
Dynamics of CRISPR-Cas9 genome interrogation in living cells
2015 StandoutScienceNobel
Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins
2018
Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases
2014 Standout
CRISPR-Cas: New Tools for Genetic Manipulations from Bacterial Immunity Systems
2015
CRISPR Correction of Duchenne Muscular Dystrophy
2018
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference
2014 StandoutNobel
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
Rational design of a split-Cas9 enzyme complex
2015 StandoutNobel
Inactivation of the Human Papillomavirus E6 or E7 Gene in Cervical Carcinoma Cells by Using a Bacterial CRISPR/Cas RNA-Guided Endonuclease
2014
Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease
2011
Evaluating and Enhancing Target Specificity of Gene-Editing Nucleases and Deaminases
2019
Programmable RNA Cleavage and Recognition by a Natural CRISPR-Cas9 System from Neisseria meningitidis
2018
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Exploiting CRISPR /C as systems for biotechnology
2013
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
Cas9-mediated targeting of viral RNA in eukaryotic cells
2015
Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems
2013 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair
2018
Works of Sara E. Howden being referenced
Simultaneous Reprogramming and Gene Correction of Patient Fibroblasts
2015
A Cas9 Variant for Efficient Generation of Indel-Free Knockin or Gene-Corrected Human Pluripotent Stem Cells
2016
Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas
2019
Chemically defined conditions for human iPSC derivation and culture
2011
Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy
2011
Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis
2013