Standout Papers

Conformational Switch of Syntaxin-1 Controls Synaptic Vesicle Fusion 2008 2026 2014 2020 222
  1. Conformational Switch of Syntaxin-1 Controls Synaptic Vesicle Fusion (2008)
    Stefan Gerber, Jong‐Cheol Rah et al. Science

Citation Impact

Citing Papers

β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
2009 StandoutNobel
Ultrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situ
2013 StandoutNobel
In vitro system capable of differentiating fast Ca 2+ -triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release
2011 Nobel
Single Reconstituted Neuronal SNARE Complexes Zipper in Three Distinct Stages
2012 StandoutScienceNobel
α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
2010 StandoutScienceNobel
Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formation
2010
A fast, single-vesicle fusion assay mimics physiological SNARE requirements
2010 StandoutNobel
Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE–Sec1/Munc18 membrane fusion complex
2010
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
The Longin SNARE VAMP7/TI-VAMP Adopts a Closed Conformation
2010
Oligomer Formation of Tau Protein Hyperphosphorylated in Cells
2014
Acetylated Tau Neuropathology in Sporadic and Hereditary Tauopathies
2013
Structural and Mutational Analysis of Functional Differentiation between Synaptotagmins-1 and -7
2010 StandoutNobel
PAINS: Relevance to Tool Compound Discovery and Fragment-Based Screening
2013
Therapeutic strategies for tau mediated neurodegeneration
2012
The effects of current density and amount of discharge on dendrite formation in the lithium powder anode electrode
2008
Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis
2010 StandoutNobel
RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction
2011 StandoutNobel
Cell biology of Ca2+-triggered exocytosis
2010 StandoutNobel
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Synaptotagmin-1 and Synaptotagmin-7 Trigger Synchronous and Asynchronous Phases of Neurotransmitter Release
2013 StandoutNobel
Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance
2013
Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle
2013 StandoutNobel
Sirtuins, Aging, and Medicine
2011
LTP Requires a Unique Postsynaptic SNARE Fusion Machinery
2013 StandoutNobel
ELKS2α/CAST Deletion Selectively Increases Neurotransmitter Release at Inhibitory Synapses
2009 StandoutNobel
The Presynaptic Active Zone
2012 StandoutNobel
Sirtuins, Aging, and Metabolism
2011
Deubiquitination of type 2 iodothyronine deiodinase by von Hippel–Lindau protein–interacting deubiquitinating enzymes regulates thyroid hormone activation
2003
From Sirtuin Biology to Human Diseases: An Update
2012
The Crystal Structure of a Munc13 C-terminal Module Exhibits a Remarkable Similarity to Vesicle Tethering Factors
2011
Tau in physiology and pathology
2015 Standout
Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice
2015
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Binding of the complexin N terminus to the SNARE complex potentiates synaptic-vesicle fusogenicity
2010
Titration of Syntaxin1 in Mammalian Synapses Reveals Multiple Roles in Vesicle Docking, Priming, and Release Probability
2013 StandoutNobel
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Role of Detergents in Conformational Exchange of a G Protein-coupled Receptor
2012 StandoutNobel
Autism-Associated Neuroligin-3 Mutations Commonly Disrupt Tonic Endocannabinoid Signaling
2013 StandoutNobel
Synaptotagmin-1 Docks Secretory Vesicles to Syntaxin-1/SNAP-25 Acceptor Complexes
2009
Lipid-Anchored SNAREs Lacking Transmembrane Regions Fully Support Membrane Fusion during Neurotransmitter Release
2013 StandoutNobel
A molecular machine for neurotransmitter release: synaptotagmin and beyond
2013 StandoutNobel
Syntaxin‐1 N‐peptide and Habc‐domain perform distinct essential functions in synaptic vesicle fusion
2012 StandoutNobel
Postsynaptic Complexin Controls AMPA Receptor Exocytosis during LTP
2012 StandoutNobel
Molecular machines governing exocytosis of synaptic vesicles
2012 Nature
Differential Regulation of Synaptic Vesicle Tethering and Docking by UNC-18 and TOM-1
2010
Calmodulin Suppresses Synaptotagmin-2 Transcription in Cortical Neurons*
2010 StandoutNobel
Complexin Clamps Asynchronous Release by Blocking a Secondary Ca2+ Sensor via Its Accessory α Helix
2010 StandoutNobel
Munc13 mediates the transition from the closed syntaxin–Munc18 complex to the SNARE complex
2011
Synaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleation
2011
The Hallmarks of Aging
2013 Standout
Synaptic Vesicle Exocytosis
2011
RIM Proteins Activate Vesicle Priming by Reversing Autoinhibitory Homodimerization of Munc13
2011 StandoutNobel
Activity-Dependent IGF-1 Exocytosis Is Controlled by the Ca2+-Sensor Synaptotagmin-10
2011 StandoutNobel
Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration
2012
The microtubule-associated tau protein has intrinsic acetyltransferase activity
2013
The epigenetics of aging and neurodegeneration
2015
Mechanisms and Function of Dendritic Exocytosis
2011
Solution NMR of SNAREs, complexin and α-synuclein in association with membrane-mimetics
2018
Membrane Bridging and Hemifusion by Denaturated Munc18
2011
At the junction of SNARE and SM protein function
2010
Comparative studies of Munc18c and Munc18-1 reveal conserved and divergent mechanisms of Sec1/Munc18 proteins
2013
Lecanemab in Early Alzheimer’s Disease
2022 Standout
Ultrastructural organization of presynaptic terminals
2011
Differential but convergent functions of Ca 2+ binding to synaptotagmin-1 C 2 domains mediate neurotransmitter release
2009 StandoutNobel
SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion
2010 StandoutNobel
Binding of UNC-18 to the N-terminus of syntaxin is essential for neurotransmission in Caenorhabditis elegans
2008
Deubiquitination of type 2 iodothyronine deiodinase by von Hippel–Lindau protein–interacting deubiquitinating enzymes regulates thyroid hormone activation
2003
Toward Safe Lithium Metal Anode in Rechargeable Batteries: A Review
2017 Standout
RIM-Binding Protein, a Central Part of the Active Zone, Is Essential for Neurotransmitter Release
2011 StandoutScienceNobel
Calcium-sensing beyond neurotransmitters: functions of synaptotagmins in neuroendocrine and endocrine secretion
2009
Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming
2009 StandoutNobel
Degradation of tau protein by autophagy and proteasomal pathways
2012
Syntaxin clusters assemble reversibly at sites of secretory granules in live cells
2010
Synaptobrevin N-terminally bound to syntaxin–SNAP-25 defines the primed vesicle state in regulated exocytosis
2010
Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation
2017
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
RIM genes differentially contribute to organizing presynaptic release sites
2012 StandoutNobel
Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome
2003
Two distinct secretory vesicle–priming steps in adrenal chromaffin cells
2010
Binding of Munc18-1 to Synaptobrevin and to the SNARE Four-Helix Bundle
2010
Principles of Allosteric Interactions in Cell Signaling
2014
Conflicting Views on the Membrane Fusion Machinery and the Fusion Pore
2009
Lysine methylation is an endogenous post-translational modification of tau protein in human brain and a modulator of aggregation propensity
2014
Membrane Fusion: Grappling with SNARE and SM Proteins
2009 StandoutScienceNobel
Protein structure prediction for the male-specific region of the human Y chromosome
2004 StandoutNobel
Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis
2010 StandoutNobel
Chemistry: Chemical con artists foil drug discovery
2014 StandoutNature
Quantitative analysis of the native presynaptic cytomatrix by cryoelectron tomography
2010
The Membrane Fusion Enigma: SNAREs, Sec1/Munc18 Proteins, and Their Accomplices—Guilty as Charged?
2012 StandoutNobel
Deconstructing complexin function in activating and clamping Ca 2+ -triggered exocytosis by comparing knockout and knockdown phenotypes
2013 StandoutNobel
Dual roles of Munc18-1 rely on distinct binding modes of the central cavity with Stx1A and SNARE complex
2011

Works of Sang-Won Min being referenced

Conformational Switch of Syntaxin-1 Controls Synaptic Vesicle Fusion
2008 StandoutScienceNobel
Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy
2010
Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury
2012
Antagonistic regulation of myogenesis by two deubiquitinating enzymes, UBP45 and UBP69
2002
Electrolyte loss and dimensional change of the negative electrode in Li powder secondary cell
2006
Rankless by CCL
2026