Citation Impact
Citing Papers
Biosynthesis of γ-butyrolactone autoregulators that switch on secondary metabolism and morphological development in Streptomyces
2007
An Acylation Cycle Regulates Localization and Activity of Palmitoylated Ras Isoforms
2005 Science
Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei
2004 Standout
Localization and activity of the SNARE Ykt6 determined by its regulatory domain and palmitoylation
2004 StandoutNobel
Rapid and selective detection of fatty acylated proteins using ω-alkynyl-fatty acids and click chemistry
2009 StandoutNobel
Thematic review series: Lipid Posttranslational Modifications. Protein palmitoylation by a family of DHHC protein S-acyltransferases
2006
The palmitoyltransferase ZDHHC20 enhances interferon-induced transmembrane protein 3 (IFITM3) palmitoylation and antiviral activity
2017
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
Thematic review series: Lipid Posttranslational Modifications. Farnesyl transferase inhibitors
2005
Hedgehog signalling in cancer formation and maintenance
2003 Standout
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions
2024 StandoutNobel
Hedgehog: functions and mechanisms
2008 Standout
Imaging beyond the proteome
2012 StandoutNobel
The mechanisms of Hedgehog signalling and its roles in development and disease
2013 Standout
Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras
2017
The SNARE Ykt6 mediates protein palmitoylation during an early stage of homotypic vacuole fusion
2003
Acyl‐CoA dehydrogenases and acyl‐CoA oxidases
2004
Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice
2011 StandoutNobel
Regulation and Functions of the ER-Associated Nrf1 Transcription Factor
2022 StandoutNobel
Ras signaling on the Golgi
2006
Cell Shape, Cytoskeletal Tension, and RhoA Regulate Stem Cell Lineage Commitment
2004 Standout
DHHC palmitoyl transferases: substrate interactions and (patho)physiology
2011
Ras proteins: different signals from different locations
2003
Trafficking and signaling by fatty-acylated and prenylated proteins
2006
Ketosynthase III as a gateway to engineering the biosynthesis of antitumoral benastatin derivatives
2008
Molecular cloning and biochemical characterization of a 3′(2′),5′‐bisphosphate nucleotidase from Debaryomyces hansenii
2005
Complement activation and choriocapillaris loss in early AMD: Implications for pathophysiology and therapy
2014
Subcellular Targeting of Salmonella Virulence Proteins by Host-Mediated S-Palmitoylation
2011
Acyl‐CoA dehydrogenases
2004
Fatty acid transport protein expression in human brain and potential role in fatty acid transport across human brain microvessel endothelial cells
2011
Remodeling of Lipid Droplets during Lipolysis and Growth in Adipocytes
2012
Palmitoylation: policing protein stability and traffic
2006
Global Analysis of Protein Palmitoylation in Yeast
2006
Medulloblastoma Growth Inhibition by Hedgehog Pathway Blockade
2002 StandoutScience
EPRS is a critical mTORC1–S6K1 effector that influences adiposity in mice
2017 Nature
The role of chemokine activation of Rac GTPases in hematopoietic stem cell marrow homing, retention, and peripheral mobilization
2006
mTOR at the nexus of nutrition, growth, ageing and disease
2020 Standout
Type 2 diabetes as an inflammatory disease
2011 Standout
Cellular fatty acid uptake: a pathway under construction
2009
MAP kinase signalling pathways in cancer
2007 Standout
Discovery of protein-palmitoylating enzymes
2008
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
2-Bromopalmitate and 2-(2-hydroxy-5-nitro-benzylidene)-benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitro
2008
The Palmitoylation Machinery Is a Spatially Organizing System for Peripheral Membrane Proteins
2010
Variations on an inhibitory theme: phasic and tonic activation of GABAA receptors
2005 Standout
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi
2008 StandoutNature
SNAREs — engines for membrane fusion
2006 Standout
Dynamics and functions of lipid droplets
2018 Standout
Swf1‐dependent palmitoylation of the SNARE Tlg1 prevents its ubiquitination and degradation
2005
Type I polyketide biosynthesis in bacteria (Part B) (1995 to mid-2000)
2001
Unraveling the therapeutic potential of the Hedgehog pathway in cancer
2013 Standout
Illumination of growth, division and secretion by metabolic labeling of the bacterial cell surface
2015 StandoutNobel
The γ2 Subunit of GABAAReceptors Is a Substrate for Palmitoylation by GODZ
2004
Age-related macular degeneration
2018 Standout
Palmitoylated proteins: purification and identification
2007
Regulating the regulator: post-translational modification of RAS
2011
Biosynthesis and attachment of novel bacterial polyketide synthase starter units
2001
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
2007 Standout
Regulation of GABAA receptor trafficking, channel activity, and functional plasticity of inhibitory synapses
2004
Platform biochemicals for a biorenewable chemical industry
2008
The on–off story of protein palmitoylation
2002
The Metabolic Phenotype in Obesity: Fat Mass, Body Fat Distribution, and Adipose Tissue Function
2017 Standout
Role of hypoxia in obesity-induced disorders of glucose and lipid metabolism in adipose tissue
2008
Pharmacological Inhibition of Protein Lipidation
2015
Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase
2004
Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork
2006
Membrane Targeting of Lipid Modified Signal Transduction Proteins
2004
Cellular palmitoylation and trafficking of lipidated peptides
2007
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Adipose tissue remodeling and obesity
2011
Drugging the undruggable RAS: Mission Possible?
2014
Purification and characterization of recombinant protein acyltransferases
2006
Quantitative Super-Resolution Microscopy of the Mammalian Glycocalyx
2019 StandoutNobel
Analysis of Two Additional Signaling Molecules in Streptomyces coelicolor and the Development of a Butyrolactone-Specific Reporter System
2009
Mutations in SUFU predispose to medulloblastoma
2002 Standout
The Crystal Structure of Yeast Fatty Acid Synthase, a Cellular Machine with Eight Active Sites Working Together
2007 StandoutNobel
IFITM3 directly engages and shuttles incoming virus particles to lysosomes
2018 StandoutNobel
The Biosynthetic Logic of Polyketide Diversity
2009 Standout
Identification of PSD-95 Palmitoylating Enzymes
2004
Cell signalling diversity of the Gqα family of heterotrimeric G proteins
2005
A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic Protein 1 in lymphopoiesis and innate immunity
2008 StandoutNobel
Avenolide, a Streptomyces hormone controlling antibiotic production in Streptomyces avermitilis
2011 StandoutNobel
Discovery and characterization of inhibitors of human palmitoyl acyltransferases
2006
Magnesium in Man: Implications for Health and Disease
2014 Standout
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Palmitoylation of oncogenic NRAS is essential for leukemogenesis
2010
Rv2131c fromMycobacterium tuberculosisIs a CysQ 3′-Phosphoadenosine-5′-phosphatase
2008 StandoutNobel
2-Bromopalmitate Analogues as Activity-Based Probes To Explore Palmitoyl Acyltransferases
2013
Myocardial Fatty Acid Metabolism in Health and Disease
2010 Standout
Model organisms lead the way to protein palmitoyltransferases
2004
Palmitoylation of Ligands, Receptors, and Intracellular Signaling Molecules
2006
Importance of Assessing Cardiorespiratory Fitness in Clinical Practice: A Case for Fitness as a Clinical Vital Sign: A Scientific Statement From the American Heart Association
2016 Standout
Adipose Tissue Free Fatty Acid Storage In Vivo: Effects of Insulin Versus Niacin as a Control for Suppression of Lipolysis
2015
Novel Lipid Modifications of Secreted Protein Signals
2004
Depalmitoylated Ras traffics to and from the Golgi complex via a nonvesicular pathway
2005
Exploring Protein Lipidation with Chemical Biology
2011
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Analysis of substrate specificity of human DHHC protein acyltransferases using a yeast expression system
2012
Adipocyte Pseudohypoxia Suppresses Lipolysis and Facilitates Benign Adipose Tissue Expansion
2014 StandoutNobel
Technology development for the production of biobased products from biorefinery carbohydrates—the US Department of Energy’s “Top 10” revisited
2010 Standout
Ras plasma membrane signalling platforms
2005
THE STRUCTURAL BIOLOGY OF TYPE II FATTY ACID BIOSYNTHESIS
2005
Genomic predictors of the maximal O2 uptake response to standardized exercise training programs
2010
Type III Polyketide Synthase β-Ketoacyl-ACP Starter Unit and Ethylmalonyl-CoA Extender Unit Selectivity Discovered by Streptomyces coelicolor Genome Mining
2006
Click-Chemistry Based High Throughput Screening Platform for Modulators of Ras Palmitoylation
2017 StandoutNobel
Palmitoylation of Intracellular Signaling Proteins: Regulation and Function
2004
Identification of palmitoylated mitochondrial proteins using a bio‐orthogonal azido‐palmitate analogue
2007 StandoutNobel
Engineered Biosynthesis of Regioselectively Modified Aromatic Polyketides Using Bimodular Polyketide Synthases
2004
Ethyl-substituted erythromycin derivatives produced by directed metabolic engineering
1998
Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies
2018
Critical nodes in signalling pathways: insights into insulin action
2006 Standout
Labeling and quantifying sites of protein palmitoylation
2004
The intracellular dynamic of protein palmitoylation
2010
K-Ras4A splice variant is widely expressed in cancer and uses a hybrid membrane-targeting motif
2015
Profiling Targets of the Irreversible Palmitoylation Inhibitor 2-Bromopalmitate
2013
New Insights into the Mechanisms of Protein Palmitoylation
2003
Rapid detection, discovery, and identification of post‐translationally myristoylated proteins during apoptosis using a bio‐orthogonal azidomyristate analog
2007 StandoutNobel
Targeting RAS Membrane Association: Back to the Future for Anti-RAS Drug Discovery?
2015
COMPARTMENTALIZED RAS/MAPK SIGNALING
2006
Works of Sandra Lobo being referenced
Erf4p and Erf2p Form an Endoplasmic Reticulum-associated Complex Involved in the Plasma Membrane Localization of Yeast Ras Proteins
2002
Interstitial deletion of 10q: Clinical features and literature review
1992
DHHC9 and GCP16 Constitute a Human Protein Fatty Acyltransferase with Specificity for H- and N-Ras
2005
Functional Analysis of Long-chain Acyl-CoA Synthetase 1 in 3T3-L1 Adipocytes
2009
Fatty acid metabolism in adipocytes: functional analysis of fatty acid transport proteins 1 and 4
2006
Identification of a Ras Palmitoyltransferase inSaccharomyces cerevisiae
2002
Fatty acid flux in adipocytes: The in's and out's of fat cell lipid trafficking
2009
Palmitoylation and Plasma Membrane Localization of Ras2p by a Nonclassical Trafficking Pathway in Saccharomyces cerevisiae
2003
Characterization of β-Ketoacyl-Acyl Carrier Protein Synthase III from Streptomyces glaucescens and Its Role in Initiation of Fatty Acid Biosynthesis
1998
Genes encoding acyl-CoA dehydrogenase (AcdH) homologues from Streptomyces coelicolor and Streptomyces avermitilis provide insights into the metabolism of small branched-chain fatty acids and macrolide antibiotic production The GenBank accession numbers for the sequences described in this paper are AF142581 (Streptomyces coelicolor) and AF143210 (Streptomyces avermitilis).
1999
In vivo and in vitro effects of thiolactomycin on fatty acid biosynthesis in Streptomyces collinus
1997