Citation Impact
Citing Papers
Signal integration in the endoplasmic reticulum unfolded protein response
2007 Standout
Steroid receptor folding by heat-shock proteins and composition of the receptor heterocomplex
1992
How stress influences the immune response
2003
Multiple cycles of global unfolding of GroEL-bound cyclophilin A evidenced by NMR
1997 StandoutNobel
The Concept of Synthetic Lethality in the Context of Anticancer Therapy
2005 StandoutNobel
The glucocorticoid receptor inhibits NFκB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain
2000
The Highly Cooperative Folding of Small Naturally Occurring Proteins Is Likely the Result of Natural Selection
2007 StandoutNobel
Destabilization of the complete protein secondary structure on binding to the chaperone GroEL
1994 StandoutNatureNobel
Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA
1991 StandoutNature
Nucleocytoplasmic Shuttling of Steroid Receptors
1995
The steroid binding domain influences intracellular solubility of the baculovirus overexpressed glucocorticoid and mineralocorticoid receptors
1993
Functional dissection of the yeast Cyc8–Tupl transcriptional co-repressor complex
1994 Nature
Hsp90 as a capacitor for morphological evolution
1998 StandoutNature
Cushing's syndrome
2015 Standout
The Engagement of Sec61p in the ER Dislocation Process
1999 StandoutNobel
Definition of a Minimal Domain of the Dioxin Receptor That Is Associated with Hsp90 and Maintains Wild Type Ligand Binding Affinity and Specificity
1995
A signature motif in transcriptional co-activators mediates binding to nuclear receptors
1997 StandoutNature
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Reduced levels of hsp90 compromise steroid receptor action in vivo
1990 Nature
The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor
1992
Evidence that the hormone binding domain of steroid receptors confers hormonal control on chimeric proteins by determining their hormone-regulated binding to heat-shock protein 90
1993
Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone
1990 Standout
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
1990 StandoutNature
Steroid Hormone Receptors: Interaction with Deoxyribonucleic Acid and Transcription Factors*
1993
Control of steroid receptor function and cytoplasmic‐nuclear transport by heat shock proteins
1992
Modulator: the missing link
1990
Uncoupled Packaging of Targeting and Cargo Molecules during Transport Vesicle Budding from the Endoplasmic Reticulum
1995 StandoutNobel
Association of heat shock protein 90 with the 16 kDa steroid binding core fragment of rat glucocorticoid receptors
1991
Protein folding in the cell
1992 StandoutNature
Foundations for engineering biology
2005 StandoutNature
A transcriptional co-repressor that interacts with nuclear hormone receptors
1995 StandoutNature
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
1999 StandoutNature
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid receptor superfamily
1990 StandoutNobel
Ubiquitin-dependent Degradation of Certain Protein Substrates in Vitro Requires the Molecular Chaperone Hsc70
1997 StandoutNobel
Hindlimb Suspension and SPE-Like Radiation Impairs Clearance of Bacterial Infections
2014 StandoutNobel
Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors
1991 Standout
Molecular chaperones in cellular protein folding
1996 StandoutNature
Calumenin, a Ca2+-binding Protein Retained in the Endoplasmic Reticulum with a Novel Carboxyl-terminal Sequence, HDEF
1997 StandoutNobel
Steroid hormone receptors: Many Actors in search of a plot
1995 Standout
Gcn4p and Novel Upstream Activating Sequences Regulate Targets of the Unfolded Protein Response
2004
Gene regulation by steroid hormones
1989 Standout
Heat shock protein 70 is associated in substoichiometric amounts with the rat hepatic glucocorticoid receptor
1993
Function/Activity of Specific Amino Acids in Glucocorticoid Receptors
1994
Differential roles of heat shock protein 70 in the in vitro nuclear import of glucocorticoid receptor and simian virus 40 large tumor antigen.
1994
Reconstitution of protein translocation from solubilized yeast membranes reveals topologically distinct roles for BiP and cytosolic Hsc70.
1993 StandoutNobel
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90.
1996
Metal oxyanion stabilization of the rat glucocorticoid receptor is independent of thiols.
1994
Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway
1998 Standout
Steroid Receptor Interactions with Heat Shock Protein and Immunophilin Chaperones*
1997 Standout
The Lumenal Domain of Sec63p Stimulates the ATPase Activity of BiP and Mediates BiP Recruitment to the Translocon in Saccharomyces cerevisiae
1997 StandoutNobel
Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis
1995 StandoutScience
Isolation of Hsp90 mutants by screening for decreased steroid receptor function.
1993
Analysis of native forms and isoform compositions of the mouse 90-kDa heat shock protein, HSP90
1991
Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale
1997 StandoutScience
Antibody fragments from a ‘single pot’ phage display library as immunochemical reagents.
1994 StandoutNobel
Proof that hsp70 is required for assembly of the glucocorticoid receptor into a heterocomplex with hsp90.
1994
Monovalent cation selectivity for ATP-dependent association of the glucocorticoid receptor with hsp70 and hsp90.
1992
Amino acid permeases require COPII components and the ER resident membrane protein Shr3p for packaging into transport vesicles in vitro.
1996 StandoutNobel
BiP and Sec63p are required for both co- and posttranslational protein translocation into the yeast endoplasmic reticulum.
1995 StandoutNobel
Long-term sensitization training in Aplysia leads to an increase in the expression of BiP, the major protein chaperon of the ER.
1992 StandoutNobel
Molecular Chaperones in the Cytosol: from Nascent Chain to Folded Protein
2002 StandoutScience
The Steroid Hormone Antagonist RU486: Mechanism at the Cellular Level and Clinical Applications
1991
Localization of the 90-kDa heat shock protein-binding site within the hormone-binding domain of the glucocorticoid receptor by peptide competition
1991
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Bidirectional transport of glucocorticoid receptors across the nuclear envelope.
1993
Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins
1989 StandoutScience
Alpha-crystallin can function as a molecular chaperone.
1992 Standout
Heat shock protein 90 as a critical factor in maintaining glucocorticosteroid receptor in a nonfunctional state.
1991
G 1 Events and Regulation of Cell Proliferation
1989 StandoutScience
Characterization of progesterone receptor binding to the 90- and 70-kDa heat shock proteins.
1991
Roles of SWI1, SWI2, and SWI3 Proteins for Transcriptional Enhancement by Steroid Receptors
1992 Science
Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily
1995 StandoutScience
A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome.
1993 StandoutNobel
NMR structure determination of the Escherichia coli DnaJ molecular chaperone: secondary structure and backbone fold of the N-terminal region (residues 2-108) containing the highly conserved J domain.
1994 StandoutNobel
Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase
1995 StandoutScience
Interaction between BiP and Sec63p is required for the completion of protein translocation into the ER of Saccharomyces cerevisiae.
1995 StandoutNobel
A multisubunit complex containing the SWI1/ADR6,SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated fromyeast.
1994 StandoutNobel
Works of Sandra Holley being referenced
A role for Hsp90 in retinoid receptor signal transduction.
1995
Mapping the HSP90 binding region of the glucocorticoid receptor.
1990