Standout Papers
Citation Impact
Citing Papers
Anti-Markovnikov alkene oxidation by metal-oxo–mediated enzyme catalysis
2017 StandoutScienceNobel
TFEB Links Autophagy to Lysosomal Biogenesis
2011 StandoutScience
Copper Chelation Enhances Antitumor Efficacy and Systemic Delivery of Oncolytic HSV
2012
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
Impairment of starvation-induced and constitutive autophagy in Atg7 -deficient mice
2005 StandoutNobel
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
2013 StandoutScience
Human high-altitude adaptation: forward genetics meets the HIF pathway
2014
High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
2011 StandoutNobel
Increased Prolyl 4-Hydroxylase Domain Proteins Compensate for Decreased Oxygen Levels
2006
Activation of autophagy induces retinal ganglion cell death in a chronic hypertensive glaucoma model
2012
The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
2017 StandoutNobel
Regulated oxygen sensing by protein hydroxylation in renal erythropoietin-producing cells
2010
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
2009 StandoutNobel
TLR2 and RIP2 Pathways Mediate Autophagy of Listeria monocytogenes via Extracellular Signal-regulated Kinase (ERK) Activation
2011
Regulation of Type II Transmembrane Serine Proteinase TMPRSS6 by Hypoxia-inducible Factors
2010 StandoutNobel
Autophagy in cancers including brain tumors: role of MicroRNAs
2020
Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases
2016 StandoutNobel
Gene-Targeting of Phd2 Improves Tumor Response to Chemotherapy and Prevents Side-Toxicity
2012
Striking Oxygen Sensitivity of the Peptidylglycine α-Amidating Monooxygenase (PAM) in Neuroendocrine Cells
2015 StandoutNobel
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
2016 StandoutNobel
Inflammatory Cytokines Protect Retinal Pigment Epithelial Cells from Oxidative Stress-Induced Death
2013
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice
2011 StandoutNobel
Tuning the autophagy-inducing activity of lanthanide-based nanocrystals through specific surface-coating peptides
2012
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy
2012
Inhibition of 2-oxoglutarate dependent oxygenases
2011
Hypoxia and Inflammation
2011 Standout
The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity
2012 StandoutNobel
Antimicrobial Autophagy: A Conserved Innate Immune Response in Drosophila
2013 Standout
HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma
2013
A novel role for 12/15-lipoxygenase in regulating autophagy
2014 StandoutNobel
Autophagy: Renovation of Cells and Tissues
2011 Standout
New Generation of Biocatalysts for Organic Synthesis
2014
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors
2011 StandoutNobel
Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration
2013
Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer
2013 StandoutNobel
The Autoimmunity-Associated Gene CLEC16A Modulates Thymic Epithelial Cell Autophagy and Alters T Cell Selection
2015
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages
2010
The Impact of the Gut Microbiota on Human Health: An Integrative View
2012 Standout
Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome
2017
HIF–prolyl hydroxylases and cardiovascular diseases
2012
A Simple Enantioconvergent and Chemoenzymatic Synthesis of Optically Active α‐Substituted Amides
2011 StandoutNobel
Studies on the Reaction of Nitric Oxide with the Hypoxia-Inducible Factor Prolyl Hydroxylase Domain 2 (EGLN1)
2011
Anti-Vascular Endothelial Growth Factors Protect Retinal Pigment Epithelium Cells Against Oxidation by Modulating Nitric Oxide Release and Autophagy
2017 Standout
Retention of prolyl hydroxylase PHD2 in the cytoplasm prevents PHD2-induced anchorage-independent carcinoma cell growth
2010
Autophagy as a target for anticancer therapy
2011
Dynamic Combinatorial Chemistry Employing Boronic Acids/Boronate Esters Leads to Potent Oxygenase Inhibitors
2012 StandoutNobel
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Prolyl-hydroxylase PHD3 interacts with pyruvate dehydrogenase (PDH)-E1β and regulates the cellular PDH activity
2014
Emerging novel functions of the oxygen-sensing prolyl hydroxylase domain enzymes
2012
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Molecular engineering of epoxide hydrolase and its application to asymmetric and enantioconvergent hydrolysis
2007
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
Regulation of Autophagy by High Glucose in Human Retinal Pigment Epithelium
2014
Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease
2009
Autophagy in immunity and inflammation
2011 StandoutNature
Exosomal secretion of α-synuclein as protective mechanism after upstream blockage of macroautophagy
2018
Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells
2018
Chaperone-mediated Autophagy Targets Hypoxia-inducible Factor-1α (HIF-1α) for Lysosomal Degradation
2013 StandoutNobel
Mitophagy Selectively Degrades Individual Damaged Mitochondria After Photoirradiation
2010
Upconversion Nanoparticles: Design, Nanochemistry, and Applications in Theranostics
2014 Standout
Integration of Oxygen Signaling at the Consensus HRE
2005
Clinical iron deficiency disturbs normal human responses to hypoxia
2016 StandoutNobel
Mitochondrial Fission, Fusion, and Stress
2012 StandoutScience
A role for autophagy in long‐term spatial memory formation in male rodents
2017
Unlocking Reactivity of TrpB: A General Biocatalytic Platform for Synthesis of Tryptophan Analogues
2017 StandoutNobel
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
The protein kinase Akt/PKB regulates both prelamin A degradation and Lmna gene expression
2013
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Oxygen-dependent ATF-4 stability is mediated by the PHD3 oxygen sensor
2007
Bioanalysis of Eukaryotic Organelles
2013
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Superoxide Ion: Generation and Chemical Implications
2016 Standout
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
A Heck–Matsuda Process for the Synthesis of β‐Arylethenesulfonyl Fluorides: Selectively Addressable Bis‐electrophiles for SuFEx Click Chemistry
2016 StandoutNobel
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Vitamin C is dispensable for oxygen sensing in vivo
2011
Comprehensive bioinformatics analysis of cell‐free protein synthesis: identification of multiple protein properties that correlate with successful expression
2009
Tetrathiomolybdate promotes tumor necrosis and prevents distant metastases by suppressing angiogenesis in head and neck cancer
2007
Copper-related diseases: From chemistry to molecular pathology
2009
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Chelators at the Cancer Coalface: Desferrioxamine to Triapine and Beyond
2006
Enantioselective Total Synthesis of Nigelladine A via Late-Stage C–H Oxidation Enabled by an Engineered P450 Enzyme
2017 StandoutNobel
Altered copper homeostasis underlies sensitivity of hepatocellular carcinoma to copper chelation
2020
Works of Sandra Barth being referenced
Determination and Modulation of Prolyl‐4‐Hydroxylase Domain Oxygen Sensor Activity
2007
How to find soluble proteins: a comprehensive analysis of alpha/beta hydrolases for recombinant expression in E. coli
2005
Hypoxia-inducible Factor Prolyl-4-hydroxylase PHD2 Protein Abundance Depends on Integral Membrane Anchoring of FKBP38
2009
Autophagy: assays and artifacts
2010
Follow-Up Study of the First Genome-Wide Association Scan in Alopecia Areata: IL13 and KIAA0350 as Susceptibility Loci Supported with Genome-Wide Significance
2012
Autophagy: cellular and molecular mechanisms
2010 Standout
The database of epoxide hydrolases and haloalkane dehalogenases: one structure, many functions
2004
The Peptidyl Prolyl cis/trans Isomerase FKBP38 Determines Hypoxia-Inducible Transcription Factor Prolyl-4-Hydroxylase PHD2 Protein Stability
2007
Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation
2005