Citation Impact
Citing Papers
Improvement of comparative model accuracy by free-energy optimization along principal components of natural structural variation
2004 StandoutNobel
Navigating the protein fitness landscape with Gaussian processes
2012 StandoutNobel
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes
2012 StandoutScienceNobel
A small-molecule switch for Golgi sulfotransferases
2004 StandoutNobel
Physically realistic homology models built with rosetta can be more accurate than their templates
2006 StandoutNobel
Protein stability promotes evolvability
2006 StandoutNobel
Evolutionary History of a Specialized P450 Propane Monooxygenase
2008 StandoutNobel
Regio- and stereoselectivity of P450-catalysed hydroxylation of steroids controlled by laboratory evolution
2011
High throughput assay for cytochrome P450 BM3 for screening libraries of substrates and combinatorial mutants
2002
Improved molecular replacement by density- and energy-guided protein structure optimization
2011 StandoutNatureNobel
Tyrosine sulfation: a modulator of extracellular protein–protein interactions
2000 StandoutNobel
Quantitative structure–pharmacokinetic/pharmacodynamic relationships
2006
Metal-Substituted Protein MRI Contrast Agents Engineered for Enhanced Relaxivity and Ligand Sensitivity
2010 StandoutNobel
Small-Molecule Inhibition of c-MYC:MAX Leucine Zipper Formation Is Revealed by Ion Mobility Mass Spectrometry
2012 StandoutNobel
Crystal structure‐based studies of cytosolic sulfotransferase
2001
Directed Evolution of the Fatty-Acid Hydroxylase P450 BM-3 into an Indole-Hydroxylating Catalyst
2000
The Active Site of the Thermophilic CYP119 from Sulfolobus solfataricus
2000
A Continuous Spectrophotometric Assay for P450 BM-3, a Fatty Acid Hydroxylating Enzyme, and Its Mutant F87A
1999
Structure-Guided Directed Evolution of Highly Selective P450-Based Magnetic Resonance Imaging Sensors for Dopamine and Serotonin
2012 StandoutNobel
Redox Control of Aryl Sulfotransferase Specificity
2000
Sulfotransferases: Structure, Mechanism, Biological Activity, Inhibition, and Synthetic Utility
2004
Crystal Structure of the Human Estrogen Sulfotransferase-PAPS Complex
2002
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Hydroxylation activity of P450 BM-3 mutant F87V towards aromatic compounds and its application to the synthesis of hydroquinone derivatives from phenolic compounds
2004
Crystal structure of SULT2A3, human hydroxysteroid sulfotransferase
2000
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
P450BM3(CYP102A1): connecting the dots
2011
Directed evolution of a magnetic resonance imaging contrast agent for noninvasive imaging of dopamine
2010 StandoutNobel
P450 BM3: the very model of a modern flavocytochrome
2002
Ellipticine, uleine, apparicine, and related alkaloids
2001
Kinetic measurements and mechanism determination of Stf0 sulfotransferase using mass spectrometry
2005 StandoutNobel
Scanning chimeragenesis: the approach used to change the substrate selectivity of fatty acid monooxygenase CYP102A1 to that of terpene ω-hydroxylase CYP4C7
2009
The structure of the cytochrome p450BM-3 haem domain complexed with the fatty acid substrate, palmitoleic acid
1997
Study of the Structural Dynamics of the E. coli 70S Ribosome Using Real-Space Refinement
2003 StandoutNobel
Laboratory evolution of a soluble, self-sufficient, highly active alkane hydroxylase
2002 StandoutNobel
Rational evolution of a medium chain-specific cytochrome P -450 BM-3 variant
2001
Conformational Plasticity and Structure/Function Relationships in Cytochromes P450
2010
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity
2022 StandoutNobel
Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains
2013 StandoutNobel
Quantitative exploration of the molecular origin of the activation of GTPase
2013 StandoutNobel
P450 Fingerprinting Method for Rapid Discovery of Terpene Hydroxylating P450 Catalysts with Diversified Regioselectivity
2011
A Large Scale Process for the Preparation of Thymitaq
2008
Positive Allosteric Systems Designed on Dynamic Supramolecular Scaffolds: Toward Switching and Amplification of Guest Affinity and Selectivity
2001
Synthesis of 2-Substituted-1H-pyrrolo[2,3-b]pyridines: Preparation of 7-azaolivacine analogue and 7-azaindolopyridopyrimidine derivatives
1997
Synthesis of ellipticine and olivacine by the thermal electrocyclic reaction via pyridine 3,4‐quinodimethane intermediates
1990
The Synthesis of a 5HT2C Receptor Agonist
2007
Organic Solvent Nanofiltration and Adsorbents; A Hybrid Approach to Achieve Ultra Low Palladium Contamination of Post Coupling Reaction Products
2008
Enantioselective α-Hydroxylation of 2-Arylacetic Acid Derivatives and Buspirone Catalyzed by Engineered Cytochrome P450 BM-3
2006 StandoutNobel
Targeted and Equally Distributed Delivery of mRNA to Organs with Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers
2023 StandoutNobel
Measurement of Deoxyribose3JHHScalar Couplings Reveals Protein Binding-Induced Changes in the Sugar Puckers of the DNA
1998 StandoutNobel
Reaction of indole-2,3-dicarboxylic anhydride with (3-bromo-4-pyridyl)triisopropoxytitanium: Synthesis of ellipticine
1996
Ring D modifications of ellipticine. Part 2. Chlorination of ellipticine via its N-oxide and synthesis and selective acetylation of 5,6,11-trimethyl-5H-benzo[b]carbazole.
1994
In the light of directed evolution: Pathways of adaptive protein evolution
2009 StandoutNobel
Development of a Scalable Process for CI-1034, an Endothelin Antagonist
2004
Large-Scale Negishi Coupling as Applied to the Synthesis of PDE472, an Inhibitor of Phosphodiesterase Type 4D
2003
Removal of Heavy Metals from Organic Reaction Mixtures: Preparation and Application of Functionalized Resins
2009
Syntheses of 4,5-Disubstituted Oxazoles via Regioselective C-4 Bromination
2007
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
2011 Standout
Membrane growth can generate a transmembrane pH gradient in fatty acid vesicles
2004 StandoutNobel
Tuning P450 Enzymes as Oxidation Catalysts
2012
Concepts in photobiology : photosynthesis and photomorphogenesis
1999
Characterization and Mutagenesis of Gal/GlcNAc-6-O-sulfotransferases
2002 StandoutNobel
Determination of enzyme/substrate specificity constants using a multiple substrate ESI-MS assay
2004
Dendron-Mediated Self-Assembly, Disassembly, and Self-Organization of Complex Systems
2009
Structural Aspects of Ligand Binding to and Electron Transfer in Bacterial and Fungal P450s
2004
Simulation of 2D NMR spectra for determination of solution conformations of nucleic acids
1992
The Art of Meeting Palladium Specifications in Active Pharmaceutical Ingredients Produced by Pd‐Catalyzed Reactions
2004
Stereoselective Enzymatic Synthesis of Heteroatom-Substituted Cyclopropanes
2018 StandoutNobel
Precise Modulation of CO2 Sorption in Ti8Ce2–Oxo Clusters: Elucidating Lewis Acidity of the Ce Metal Sites and Structural Flexibility
2024 StandoutNobel
Carbohydrate Sulfotransferases of the GalNAc/Gal/GlcNAc6ST Family
2002 StandoutNobel
Hydrocarbon Hydroxylation by Cytochrome P450 Enzymes
2009
Development of an Efficient Synthesis of the Pyrrolquinolone PHA-529311
2006
Single-molecule height measurements on microsomal cytochrome P450 in nanometer-scale phospholipid bilayer disks
2002
A sulfated metabolite produced bystf3negatively regulates the virulence ofMycobacteriumtuberculosis
2006 StandoutNobel
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag
2009 StandoutNobel
Accurate protein structure modeling using sparse NMR data and homologous structure information
2012 StandoutNobel
An Efficient Method for Removal of Residual Palladium from Organic Solution of Faropenem Sodium in the Pd(II)-Catalyzed Cleavage of Allyl Faropenem
2010
A Redox-Switchable α-Cyclodextrin-Based [2]Rotaxane
2008 StandoutNobel
Isomeric ellipticines. Part 1. Synthesis of two linear isomers of the antitumour alkaloid ellipticine
1992
Enzymatic Mechanisms of Phosphate and Sulfate Transfer
2006
Comparative Protein Structure Modeling of Genes and Genomes
2000 Standout
A Novel Methodology for Efficient Removal of Residual Palladium from a Product of the Suzuki−Miyaura Coupling with Polymer-Supported Ethylenediamine Derivatives
2003
Comparative Protein Structure Modeling Using MODELLER
2007 Standout
Protein Structure Prediction and Structural Genomics
2001 StandoutScienceNobel
Identification of Mechanism-Based Inactivation in P450-Catalyzed Cyclopropanation Facilitates Engineering of Improved Enzymes
2016 StandoutNobel
Iminophosphorane-mediated synthesis of fused carbazoles. A facile one-pot preparation of 7H-pyrido [4,3-c]carbazole and 10H-pyrido[3,4-b]carbazole derivatives.
1991
Intrinsic Disorder and Protein Function
2002
Controlled Oxidation of Remote sp3 C–H Bonds in Artemisinin via P450 Catalysts with Fine-Tuned Regio- and Stereoselectivity
2012
Engineering Cytochrome P450 BM3 for Terminal Alkane Hydroxylation
2006 StandoutNobel
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
Palladium-Catalyzed Regioselective Arylation of Imidazo[1,2-b][1,2,4]triazine: Synthesis of an α2/3-Selective GABA Agonist
2005
Practical Asymmetric Synthesis of a Potent Cathepsin K Inhibitor. Efficient Palladium Removal Following Suzuki Coupling
2003
Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers
2021 StandoutNobel
Process Development and Scale Up of a Glycine Antagonist
2009
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Industrial R&D on Catalytic CC and CN Coupling Reactions: A Personal Account on Goals, Approaches and Results
2004
Roles of key active-site residues in flavocytochrome P450 BM3
1999
Efficient synthesis of 5-demethyl-6-methylisoellipticine and utilization of the methodology to prepare angular and linear pyridocarbazoles
1991
Recent Applications of Palladium‐Catalyzed Coupling Reactions in the Pharmaceutical, Agrochemical, and Fine Chemical Industries
2009
Regio- and Enantioselective Alkane Hydroxylation with Engineered Cytochromes P450 BM-3
2003 StandoutNobel
Allosteric Modulation of Substrate Binding within a Tetracationic Molecular Receptor
2015 StandoutNobel
Alternate Heme Ligation Steers Activity and Selectivity in Engineered Cytochrome P450-Catalyzed Carbene-Transfer Reactions
2018 StandoutNobel
Applications of Fluorine in Medicinal Chemistry
2015 Standout
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
Fatty Acid-Induced Alteration of the Porphyrin Macrocycle of Cytochrome P450 BM3
1998
Selection and Development of the Manufacturing Route for EP1 Antagonist GSK269984B
2010
Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site
2023 StandoutNobel
Isolation and Synthesis of Biologically Active Carbazole Alkaloids
2002 Standout
Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach
2002 StandoutNobel
Discovery of Potent Parthenolide-Based Antileukemic Agents Enabled by Late-Stage P450-Mediated C—H Functionalization
2013
Enzyme-Controlled Nitrogen-Atom Transfer Enables Regiodivergent C–H Amination
2014 StandoutNobel
Optimization and Scale-Up of a Suzuki−Miyaura Coupling Reaction: Development of an Efficient Palladium Removal Technique
2008
Comparative Protein Structure Modeling Using Modeller
2006 Standout
Pivotal Role of Water in the Mechanism of P450BM-3
2001
Enantioselective Total Synthesis of Nigelladine A via Late-Stage C–H Oxidation Enabled by an Engineered P450 Enzyme
2017 StandoutNobel
Structural Adaptability Facilitates Histidine Heme Ligation in a Cytochrome P450
2015 StandoutNobel
Works of Sandeep Modi being referenced
Crystal structure of the FMN‐binding domain of human cytochrome P450 reductase at 1.93 Å resolution
1999
Structure–activity relationship for human cytochrome P450 substrates and inhibitors
2002
NMR Studies of Substrate Binding to Cytochrome P450 BM3: Comparisons to Cytochrome P450 cam
1995
Quantification of DNA structure from NMR data: conformation of d-ACATCGATGT
1989
X-ray Crystal Structure of Human Dopamine Sulfotransferase, SULT1A3
1999
Crystal Structure of Human Cytochrome P450 2D6
2005
Steady‐State and Picosecond‐Time‐Resolved Fluorenscence Studies on the Recombinant Heme Domain of Bacillus megaterium Cytochrome P‐450
1997
ADMET rules of thumb II: A comparison of the effects of common substituents on a range of ADMET parameters
2009
An efficient synthesis of C-11 substituted 6H-pyrido[4,3-b]carbazoles
1991
Engineering the substrate specificity of Bacillus megaterium cytochrome P-450 BM3: hydroxylation of alkyl trimethylammonium compounds
1997
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine as a Substrate of Cytochrome P450 2D6: Allosteric Effects of NADPH−Cytochrome P450 Reductase
1997
Reaction of 4-methylpyrano[3,4-b]indol-3-one with (dimethyltriazen-1-yl)pyridinecarboxylic acids, precursors of 3,4-pyridynes
1989
Effect of replacement of ferriprotoporphyrin IX in the haem domain of cytochrome P-450 BM-3 on substrate binding and catalytic activity
1995
Synthesis of 6h-pyrido[4,3-b]carbazoles
1990
Removal of Palladium from Organic Reaction Mixtures by Trimercaptotriazine
1997
Synthesis of 5-methyl-6h-pyrido[4,3-b]carbazole-11-methanol
1990
Determinants of the substrate specificity of human cytochrome P-450 CYP2D6: design and construction of a mutant with testosterone hydroxylase activity
1998
A Model for Human Cytochrome P450 2D6 Based on Homology Modeling and NMR Studies of Substrate Binding
1996
The role of surface-exposed Tyr-83 of plastocyanin in electron transfer from cytochrome c
1992
A Single Mutation in Cytochrome P450 BM3 Changes Substrate Orientation in a Catalytic Intermediate and the Regiospecificity of Hydroxylation
1997
Synthesis of 6-substituted 7H-pyrido[4,3-c]carbazoles
1989
The surface-exposed tyrosine residue Tyr83 of pea plastocyanin is involved in both binding and electron transfer reactions with cytochrome f.
1991