Citation Impact
Citing Papers
An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins
2020 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Functional diversity of helper T lymphocytes
1996 StandoutNature
Elevated levels of protein-bound p-hydroxyphenylacetaldehyde, an amino-acid-derived aldehyde generated by myeloperoxidase, are present in human fatty streaks, intermediate lesions and advanced atherosclerotic lesions
2000
Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
2000 StandoutNature
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Inflammation and cancer
2002 StandoutNature
Molecular Chlorine Generated by the Myeloperoxidase-Hydrogen Peroxide-Chloride System of Phagocytes Converts Low Density Lipoprotein Cholesterol into a Family of Chlorinated Sterols
1996
Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro
1999
Superoxide and hydrogen peroxide in relation to mammalian cell proliferation
1995
Complement Receptors CD21/35 Link Innate and Protective Immunity during Streptococcus pneumoniae Infection by Regulating IgG3 Antibody Responses
2002
Carcinogen-mediated oxidant formation and oxidative DNA damage
1992
Proteolytic inactivation of alpha-1-proteinase inhibitor by a neutrophil metalloproteinase.
1988
Estrogen receptor α is a major mediator of 17β-estradiol’s atheroprotective effects on lesion size in Apoe–/– mice
2001 StandoutNobel
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
1994 Standout
Plasma hydrogen peroxide production in hypertensives and normotensive subjects at genetic risk of hypertension
1998
Tissue Destruction by Neutrophils
1989 Standout
Class B Scavenger Receptors CD36 and SR-BI Are Receptors for Hypochlorite-modified Low Density Lipoprotein
2003
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
IRP1 Activation by Extracellular Oxidative Stress in the Perfused Rat Liver
2001
3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.
1997 Standout
The Immunobiology of Eosinophils
1991
Hypochlorous Acid Oxygenates the Cysteine Switch Domain of Pro-matrilysin (MMP-7)
2001
Synthetic mimics of mammalian cell surface receptors: prosthetic molecules that augment living cells
2005
The eosinophil and bronchial asthma: Current understanding
1990
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
The Serpin α1-Proteinase Inhibitor Is a Critical Substrate for Gelatinase B/MMP-9 In Vivo
2000
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
Pulmonary immune cells in health and disease: the eosinophil leucocyte (Part I)
1994
Sunburn and p53 in the onset of skin cancer
1994 StandoutNature
Neutrophils and Host Defense
1988
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Hypochlorite-induced oxidation of amino acids, peptides and proteins
2003
Macrophage-induced angiogenesis is mediated by tumour necrosis factor-α
1987 StandoutNature
DNA Damage and Oxygen Radical Toxicity
1988 StandoutScience
Lysine Residues Direct the Chlorination of Tyrosines in YXXK Motifs of Apolipoprotein A-I When Hypochlorous Acid Oxidizes High Density Lipoprotein
2004
Matrix metalloproteinases as modulators of inflammation and innate immunity
2004 Standout
Myeloperoxidase-generated oxidants and atherosclerosis
2000
Sickle-cell disease
2010 Standout
Increased atherosclerosis in myeloperoxidase-deficient mice
2001
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability.
1996
Pulmonary Strategies of Antioxidant Defense
1989
MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation
2002 StandoutNatureNobel
Role of controlled cardiac reoxygenation in reducing nitric oxide production and cardiac oxidant damage in cyanotic infantile hearts.
1994 StandoutNobel
Atherosclerosis — An Inflammatory Disease
1999 Standout
Inflammation in atherosclerosis
2002 StandoutNature
Nitrogen dioxide radical generated by the myeloperoxidase‐hydrogen peroxide‐nitrite system promotes lipid peroxidation of low density lipoprotein
1999
Formation of Nitrating and Chlorinating Species by Reaction of Nitrite with Hypochlorous Acid
1996
Ascorbate: The Most Effective Antioxidant in Human Blood Plasma
1990
Formation of Reactive Nitrogen Species during Peroxidase-catalyzed Oxidation of Nitrite
1997
AKT/PKB Signaling: Navigating the Network
2017 Standout
Chlorination of Tyrosyl Residues in Peptides by Myeloperoxidase and Human Neutrophils
1995
A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q
2006 StandoutNobel
Hypochlorite-modified low-density lipoprotein stimulates human polymorphonuclear leukocytes for enhanced production of reactive oxygen metabolites, enzyme secretion, and adhesion to endothelial cells
1998
The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells
2008 StandoutNobel
Points of control in inflammation
2002 StandoutNature
A matrix metalloproteinase expressed on the surface of invasive tumour cells
1994 StandoutNature
Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils
1998 Nature
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Hypochlorous Acid Generated by Myeloperoxidase Modifies Adjacent Tryptophan and Glycine Residues in the Catalytic Domain of Matrix Metalloproteinase-7 (Matrilysin)
2003
Immunogenicity of protein therapeutics
2007
Eosinophils: Biology and Role in Disease
1995
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Reactions of Hypochlorous Acid with Tyrosine and Peptidyl-tyrosyl Residues Give Dichlorinated and Aldehydic Products in Addition to 3-Chlorotyrosine
2000
Cancer vaccines and carbohydrate epitopes
2011
Atherosclerosis
2001 Standout
Oxidative cross-linking of immune complexes by human polymorphonuclear leukocytes.
1988
Oxidants and antioxidants in the pathogenesis of atherosclerosis: implications for the oxidized low density lipoprotein hypothesis
1998
Neutrophils convert tyrosyl residues in albumin to chlorotyrosine
1996
The myeloperoxidase system of human phagocytes generates Nε-(carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation
1999
Metal ions and oxygen radical reactions in human inflammatory joint disease
1985
Resistance of human tumor cells in vitro to oxidative cytolysis.
1985
Complement Activation Contributes to Hypoxic-Ischemic Brain Injury in Neonatal Rats
2003
Vitamin C protects against and reverses specific hypochlorous acid- and chloramine-dependent modifications of low-density lipoprotein
2000
Expression of Neutrophil Collagenase (Matrix Metalloproteinase-8) in Human Atheroma
2001
An activity in rat tissues that modifies nitrotyrosine-containing proteins
1998 StandoutNobel
Hypochlorite-induced oxidation of proteins in plasma: formation of chloramines and nitrogen-centred radicals and their role in protein fragmentation
1999
Mass spectrometric quantification of amino acid oxidation products in proteins: insights into pathways that promote LDL oxidation in the human artery wall
1999
The dual function of the splenic marginal zone: essential for initiation of anti-TI-2 responses but also vital in the general first-line defense against blood-borne antigens
2002
Studies of controlled reperfusion after ischemia
1990
The importance of free radicals and catalytic metal ions in human diseases
1985
The C-type lectin SIGN-R1 mediates uptake of the capsular polysaccharide ofStreptococcus pneumoniaein the marginal zone of mouse spleen
2003 StandoutNobel
Free Radicals as Mediators of Tissue Injury
1991
Detection of HOCl-mediated protein oxidation products in the extracellular matrix of human atherosclerotic plaques
2003
Prooxidant States and Tumor Promotion
1985 StandoutScience
Oxidation of low-density lipoprotein with hypochlorite causes transformation of the lipoprotein into a high-uptake form for macrophages
1993
Dityrosine, a specific marker of oxidation, is synthesized by the myeloperoxidase-hydrogen peroxide system of human neutrophils and macrophages.
1993
Fragmentation of extracellular matrix by hypochlorous acid
2003
[1] Role of free radicals and catalytic metal ions in human disease: An overview
1990 Standout
Oxidative Stress, Caloric Restriction, and Aging
1996 StandoutScience
Stomatin, flotillin-1, and flotillin-2 are major integral proteins of erythrocyte lipid rafts
2001
Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response.
1981 StandoutNobel
Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils
1997 StandoutNobel
The intriguing role of polymorphonuclear neutrophils in antitumor reactions
2001
Granules of the Human Neutrophilic Polymorphonuclear Leukocyte
1997 Standout
Neutrophils degrade subendothelial matrices in the presence of alpha-1-proteinase inhibitor. Cooperative use of lysosomal proteinases and oxygen metabolites.
1984
Science and technology for water purification in the coming decades
2008 StandoutNature
Central Role for G Protein-Coupled Phosphoinositide 3-Kinase γ in Inflammation
2000 Science
[40] Preparation and characterization of chloramines
1986
Collagenolytic metalloenzymes of the human neutrophil
1986
Neutrophil Extracellular Traps Kill Bacteria
2004 StandoutScience
Degradation of human glomerular basement membrane by stimulated neutrophils. Activation of a metalloproteinase(s) by reactive oxygen metabolites.
1987
The antioxidant action of human extracellular fluids. Effect of human serum and its protein components on the inactivation of α1-antiproteinase by hypochlorous acid and by hydrogen peroxide
1987
Interleukin-13: Central Mediator of Allergic Asthma
1998 StandoutScience
Chlorination of endogenous amines by isolated neutrophils. Ammonia-dependent bactericidal, cytotoxic, and cytolytic activities of the chloramines.
1984
Bilirubin Is an Antioxidant of Possible Physiological Importance
1987 StandoutScience
Pericellular proteolysis by neutrophils in the presence of proteinase inhibitors: effects of substrate opsonization.
1988
New mechanism for glomerular injury. Myeloperoxidase-hydrogen peroxide-halide system.
1987
The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family.
1990
Activation of the endogenous metalloproteinase, gelatinase, by triggered human neutrophils.
1986
Secretory products of macrophages.
1987 Standout
Endothelial cells in physiology and in the pathophysiology of vascular disorders.
1998 Standout
Matrix Metalloproteinases: A Review
1993 Standout
The antioxidant action of taurine, hypotaurine and their metabolic precursors
1988
Enhancement of Antibodies to the Human Immunodeficiency Virus Type 1 Envelope by Using the Molecular Adjuvant C3d
2003
Noncovalent Cell Surface Engineering: Incorporation of Bioactive Synthetic Glycopolymers into Cellular Membranes
2008 StandoutNobel
Singlet oxygen production by human eosinophils.
1988
Lipopolysaccharide modulates the expression of alpha 1 proteinase inhibitor and other serine proteinase inhibitors in human monocytes and macrophages.
1987
Oxygen-derived Free Radicals in the Pathogenesis of Parasitic Disease
1986
Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes
2014 StandoutNobel
Works of Samuel T. Test being referenced
Activation of the alternative pathway of complement by calcium-loaded erythrocytes resulting from loss of membrane phospholipid asymmetry
1997
In Vitro Incorporation of GPI-Anchored Proteins Into Human Erythrocytes and Their Fate in the Membrane
1998
Decrease of Very Late Activation Antigen-4 and CD36 on Reticulocytes in Sickle Cell Patients Treated With Hydroxyurea
1997
Quantitative and temporal characterization of the extracellular H2O2 pool generated by human neutrophils.
1984
Long-Lived Oxidants Generated by Human Neutrophils: Characterization and Bioactivity
1983 Science
Generation of nitrogen-chlorine oxidants by human phagocytes.
1984
Effect of Tumor Necrosis Factor on the Generation of Chlorinated Oxidants by Adherent Human Neutrophils
1991
Oxidative regulation of neutrophil elastase-alpha-1-proteinase inhibitor interactions.
1986
Oxidative Autoactivation of Latent Collagenase by Human Neutrophils
1985 Science
Increased Immunogenicity and Induction of Class Switching by Conjugation of Complement C3d to Pneumococcal Serotype 14 Capsular Polysaccharide
2001
Brominating Oxidants Generated by Human Eosinophils
1986 Science
[23] Assay of the extracellular hydrogen peroxide pool generated by phagocytes
1986