Citation Impact
Citing Papers
Linkage Map ofEscherichia coliK-12, Edition 10: The Traditional Map
1998
Radiation-Induced CXCL16 Release by Breast Cancer Cells Attracts Effector T Cells
2008
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Methionine to Glutamine Substitutions in the C-terminal Domain of Calmodulin Impair the Activation of Three Protein Kinases
1996
Differential function of Tie2 at cell–cell contacts and cell–substratum contacts regulated by angiopoietin-1
2008
Dynamic personalities of proteins
2007 StandoutNature
Interaction between Caveolin-1 and the Reductase Domain of Endothelial Nitric-oxide Synthase
1998
Calmodulin activation and inhibition of skeletal muscle Ca2+ release channel (ryanodine receptor)
1995
Oncogenic kinase signalling
2001 StandoutNature
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Pharmacological modulation of nitric oxide synthesis by mechanism-based inactivators and related inhibitors
1999
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF
1999
Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca2+ release channel
2007 StandoutNobel
Contrasting Actions of Selective Inhibitors of Angiopoietin-1 and Angiopoietin-2 on the Normalization of Tumor Blood Vessels
2009
Liver fibrosis – from bench to bedside
2003 Standout
Munc18-1 Promotes Large Dense-Core Vesicle Docking
2001 StandoutNobel
The metabolic syndrome
2010 Standout
Macrophages in the Pathogenesis of Atherosclerosis
2011 Standout
Functional Consequences of Truncating Amino Acid Side Chains Located at a Calmodulin-Peptide Interface
1997
Tryptophan 409 Controls the Activity of Neuronal Nitric-oxide Synthase by Regulating Nitric Oxide Feedback Inhibition
1999
Angiogenesis in cancer and other diseases
2000 StandoutNature
Tumor‐induced tolerance and immune suppression by myeloid derived suppressor cells
2008
In Situ Expression of Angiopoietins in Astrocytomas Identifies Angiopoietin-2 as an Early Marker of Tumor Angiogenesis
1999
The biology of VEGF and its receptors
2003 Standout
Role of Reductase Domain Cluster 1 Acidic Residues in Neuronal Nitric-oxide Synthase
1999
Three-dimensional structure of myosin subfragment-1: a molecular motor
1993 StandoutScience
Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2–Tie2 complex
2006
Structural basis for endothelial nitric oxide synthase binding to calmodulin
2003
Deletion of the Carboxyl Terminus of Tie2 Enhances Kinase Activity, Signaling, and Function
2002
Nitric oxide synthases: structure, function and inhibition
2001 Standout
Nitric Oxide: Physiological Roles, Biosynthesis and Medical Uses
1999
The metabolic syndrome
2005 Standout
Regulation of β-Adrenergic Receptor Signaling by S-Nitrosylation of G-Protein-Coupled Receptor Kinase 2
2007 StandoutNobel
Clostridial neurotoxins: new tools for dissecting exocytosis
1994
Regulation of angiogenesis by hypoxia: role of the HIF system
2003 StandoutNobel
Evolutionarily Conserved Multiple C2 Domain Proteins with Two Transmembrane Regions (MCTPs) and Unusual Ca2+ Binding Properties
2004 StandoutNobel
Catheter-based adenovirus-mediated anti-monocyte chemoattractant gene therapy attenuates in-stent neointima formation in cynomolgus monkeys
2006
A Kinetic Simulation Model That Describes Catalysis and Regulation in Nitric-oxide Synthase
2001
Calmodulin: a prototypical calcium sensor
2000
Calmodulin Suppresses Synaptotagmin-2 Transcription in Cortical Neurons*
2010 StandoutNobel
Hypoxia and Vascular Endothelial Growth Factor Selectively Up-regulate Angiopoietin-2 in Bovine Microvascular Endothelial Cells
1999
Characterization of the Reductase Domain of Rat Neuronal Nitric Oxide Synthase Generated in the Methylotrophic Yeast Pichia pastoris
1996
Vascular-specific growth factors and blood vessel formation
2000 StandoutNature
A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension
2005
Cancer immunotherapy comes of age
2011 StandoutNature
Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold
1995 StandoutNobel
Clinical applications of angiogenic growth factors and their inhibitors
1999
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
Structure of the Tie2 RTK Domain
2000
Structure of the Calmodulin αII-Spectrin Complex Provides Insight into the Regulation of Cell Plasticity
2006 StandoutNobel
Symmetrical Mutant Phenotypes of the Receptor EphB4 and Its Specific Transmembrane Ligand ephrin-B2 in Cardiovascular Development
1999
Calcium Signaling
2007 Standout
The Ferrous-dioxy Complex of Neuronal Nitric Oxide Synthase
1997
Human DNA Damage Checkpoint Protein hRAD9 Is a 3′ to 5′ Exonuclease
2000 StandoutNobel
C‐reactive protein, its role in inflammation, Type 2 diabetes and cardiovascular disease, and the effects of insulin‐sensitizing treatment with thiazolidinediones
2004
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system
2009
Mammalian nitric oxide synthases
1999
Calmodulin and the regulation of smooth muscle contraction
1994
Angiogenesis as a therapeutic target
2005 StandoutNature
Expression of the angiopoietins and their receptor Tie2 in human renal clear cell carcinomas; regulation by the von Hippel‐Lindau gene and hypoxia
2002
Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin
1997 StandoutNatureNobel
Anemia of Chronic Disease
2005 Standout
Targeting the tumour vasculature: insights from physiological angiogenesis
2010
Diagnosis and Management of the Metabolic Syndrome
2005 Standout
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
2001 Standout
Angiopoietin-1 inhibits vascular permeability, angiogenesis, and growth of hepatic colon cancer tumors.
2003
Calmodulin as an Ion Channel Subunit
2002
Magnetic Iron Oxide Nanoparticles: Synthesis, Stabilization, Vectorization, Physicochemical Characterizations, and Biological Applications
2008 Standout
Mouse 4T1 Breast Tumor Model
2000
Activation of calcineurin and smooth muscle myosin light chain kinase by Met-to-Leu mutants of calmodulin
1998 StandoutNobel
PKD2 , a Gene for Polycystic Kidney Disease That Encodes an Integral Membrane Protein
1996 StandoutScience
Synapsins regulate use-dependent synaptic plasticity in the calyx of Held by a Ca 2+ /calmodulin-dependent pathway
2006 StandoutNobel
Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery
2013
F‐domain valency determines outcome of signaling through the angiopoietin pathway
2021 StandoutNobel
Membrane Fusion and Exocytosis
1999 StandoutNobel
Drug Delivery Systems: Entering the Mainstream
2004 StandoutScience
Activation of four enzymes by two series of calmodulin mutants with point mutations in individual Ca2+ binding sites.
1993
Angiopoietin-1/Tie2 receptor signaling in vascular quiescence and angiogenesis.
2010
Structures and metal-ion-binding properties of the Ca2+-binding helix–loop–helix EF-hand motifs
2007
Peptide blockade of HIFα degradation modulates cellular metabolism and angiogenesis
2002 StandoutNobel
Functional delineation of the Ca(2+)-deficient EF-hand in cardiac muscle, with genetically engineered cardiac-skeletal chimeric troponin C.
1992
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
Metal–Organic Frameworks in Biomedicine
2011 Standout
Target Enzyme Recognition by Calmodulin: 2.4 Å Structure of a Calmodulin-Peptide Complex
1992 Science
Endothelial dysfunction and inflammation—is there a link?
2001
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
2014 StandoutNobel
A Solid-Phase Approach to Mouse Melanocortin Receptor Agonists Derived from a Novel Thioether Cyclized Peptidomimetic Scaffold
2002 StandoutNobel
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4
2013 StandoutNobel
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
The effect of Met–>Leu mutations on calmodulin's ability to activate cyclic nucleotide phosphodiesterase.
1994
Dynamic and quantitative Ca 2+ measurements using improved cameleons
1999 StandoutNobel
Works of Samuel E. George being referenced
Effects of Arginase Isoforms on NO Production by nNOS
2002
Gene transfer of the neuronal NO synthase isoform to cirrhotic rat liver ameliorates portal hypertension
2000
The Calmodulin-Nitric Oxide Synthase Interaction
1995
Neuronal Nitric-oxide Synthase Interaction with Calmodulin-Troponin C Chimeras
1998
Calmodulin is intrinsically LESS effective than troponin C in activating skeletal muscle contraction
1994
Role of domain 3 of calmodulin in activation of calmodulin-stimulated phosphodiesterase and smooth muscle myosin light chain kinase
1994
Calmodulin-cardiac troponin C chimeras. Effects of domain exchange on calcium binding and enzyme activation.
1993
Nitric Oxide Synthase in Atherosclerosis and Vascular Injury
2000
Cloning and molecular characterization of csm mutations allowing expression of catabolite-repressible operons in the absence of exogenous cyclic AMP
1986
Acute Host-Mediated Endothelial Injury After Adenoviral Gene Transfer in Normal Rabbit Arteries
1998
The Fourth EF-Hand of Calmodulin and Its Helix−Loop−Helix Components: Impact on Calcium Binding and Enzyme Activation
1996
Chimeric calmodulin-cardiac troponin C proteins differentially activate calmodulin target enzymes.
1990
Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2
1998
Structural Determinants of Ca2+ Exchange and Affinity in the C Terminal of Cardiac Troponin C
1998
Calmodulin activation of target enzymes. Consequences of deletions in the central helix.
1990