Standout Papers
Citation Impact
Citing Papers
The Hepatitis C Virus NS3 Protein: A Model RNA Helicase and Potential Drug Target
2007
Protein interaction networks revealed by proteome coevolution
2019 StandoutScienceNobel
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
Principles for designing proteins with cavities formed by curved β sheets
2017 StandoutScienceNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Protein structure determination using metagenome sequence data
2017 StandoutScienceNobel
Hallucinating symmetric protein assemblies
2022 StandoutScienceNobel
Structural Roles for Human Translation Factor eIF3 in Initiation of Protein Synthesis
2005 StandoutScienceNobel
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
2020 StandoutScienceNobel
Sculpting conducting nanopore size and shape through de novo protein design
2024 StandoutScienceNobel
The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target.
2007
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism
2009 StandoutNobel
MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability
2013 Standout
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Fast and accurate protein structure search with Foldseek
2023 Standout
The 3D mutational constraint on amino acid sites in the human proteome
2022
The Spring α-Helix Coordinates Multiple Modes of HCV (Hepatitis C Virus) NS3 Helicase Action
2016 StandoutNobel
COFACTOR: an accurate comparative algorithm for structure-based protein function annotation
2012
Structural Basis for Gating and Activation of RyR1
2016 StandoutNobel
The Pfam protein families database: towards a more sustainable future
2015 Standout
Structural basis for DNA duplex separation by a superfamily-2 helicase
2007
PcrA Helicase Dismantles RecA Filaments by Reeling in DNA in Uniform Steps
2010
MicroRNAs
2004 Standout
Common determinants in DNA melting and helicase-catalysed DNA unwinding by papillomavirus replication protein E1
2006
RepeatsDB: a database of tandem repeat protein structures
2013
RecA-like motor ATPases—lessons from structures
2004
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome
2013 StandoutNatureNobel
UvrD Helicase Unwinds DNA One Base Pair at a Time by a Two-Part Power Stroke
2006
Bacterial DNA repair: recent insights into the mechanism of RecBCD, AddAB and AdnAB
2012
Two Novel Conserved Motifs in the Hepatitis C Virus NS3 Protein Critical for Helicase Action
2003
X-Ray Structures of the Sulfolobus solfataricus SWI2/SNF2 ATPase Core and Its Complex with DNA
2005
Pfam: the protein families database
2013 Standout
The TOPCONS web server for consensus prediction of membrane protein topology and signal peptides
2015
Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity
2014 StandoutNobel
Crystal structure refinement withSHELXL
2014 Standout
RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP
2006 Nature
A Brownian motor mechanism of translocation and strand separation by hepatitis C virus helicase
2005
What recent ribosome structures have revealed about the mechanism of translation
2009 StandoutNatureNobel
Asymmetry in the Assembly of the RNAi Enzyme Complex
2003 Standout
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
2017 StandoutNatureNobel
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
Mechanistic Basis of 5′-3′ Translocation in SF1B Helicases
2009
Integrating sequence and structural biology with DAS
2007
Structural and Biological Identification of Residues on the Surface of NS3 Helicase Required for Optimal Replication of the Hepatitis C Virus
2005
The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
2016 StandoutNatureNobel
High-resolution structure prediction and the crystallographic phase problem
2007 StandoutNatureNobel
The Universal Protein Resource (UniProt)
2004 Standout
A crystallographic perspective on sharing data and knowledge
2014
Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein
2008
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
Clue to damage recognition by UvrB: residues in the beta-hairpin structure prevent binding to non-damaged DNA
2001
RNA helicases — one fold for many functions
2007
Crystal Structure of the Helicase Domain from the Replicative Helicase-Primase of Bacteriophage T7
1999
Mutation effects predicted from sequence co-variation
2017
MobiDB 2.0: an improved database of intrinsically disordered and mobile proteins
2014
mRNA Helicase Activity of the Ribosome
2005
Visualizing ATP-Dependent RNA Translocation by the NS3 Helicase from HCV
2010
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
Revealing the world of RNA interference
2004 StandoutNatureNobel
Mechanism of folding chamber closure in a group II chaperonin
2010 StandoutNatureNobel
Conserved XPB Core Structure and Motifs for DNA Unwinding: Implications for Pathway Selection of Transcription or Excision Repair
2006
Repetitive shuttling of a motor protein on DNA
2005 Nature
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
Exploiting structure similarity in refinement: automated NCS and target-structure restraints inBUSTER
2012
Exploring the repeat protein universe through computational protein design
2015 StandoutNatureNobel
Crystal Structure of T7 Gene 4 Ring Helicase Indicates a Mechanism for Sequential Hydrolysis of Nucleotides
2000
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Cryo-EM structure of a type IV secretion system
2022 StandoutNatureNobel
The worldwide Protein Data Bank (wwPDB): ensuring a single, uniform archive of PDB data
2006
Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System
2015 StandoutNobel
The HDOCK server for integrated protein–protein docking
2020
Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29
2013 StandoutNobel
Hepatitis C Virus NS3 and Simian Virus 40 T Antigen Helicases Displace Streptavidin from 5‘-Biotinylated Oligonucleotides but Not from 3‘-Biotinylated Oligonucleotides: Evidence for Directional Bias in Translocation on Single-Stranded DNA
2002
RecBCD Enzyme and the Repair of Double-Stranded DNA Breaks
2008
The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures
2019
MolProbity: More and better reference data for improved all‐atom structure validation
2017 Standout
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
PDBsum: Structural summaries of PDB entries
2017
The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling
2005 Standout
The EMBL-EBI search and sequence analysis tools APIs in 2019
2019 Standout
MOLEonline: a web-based tool for analyzing channels, tunnels and pores (2018 update)
2018
Single–Base Pair Unwinding and Asynchronous RNA Release by the Hepatitis C Virus NS3 Helicase
2011 Science
Structure and Mechanism of Helicases and Nucleic Acid Translocases
2007
ComplexContact: a web server for inter-protein contact prediction using deep learning
2018
Assignment of protein sequences to existing domain and family classification systems: Pfam and the PDB
2012
The arginine finger of bacteriophage T7 gene 4 helicase: Role in energy coupling
2004
The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update
2018 Standout
Structure of Hexameric DnaB Helicase and Its Complex with a Domain of DnaG Primase
2007 StandoutScienceNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase
2001
CASTp 3.0: computed atlas of surface topography of proteins
2018 Standout
Jalview Version 2—a multiple sequence alignment editor and analysis workbench
2009 Standout
Works of Sameer Velankar being referenced
Modeling protein–protein and protein–peptide complexes: CAPRI 6th edition
2016
AlphaFold2 reveals commonalities and novelties in protein structure space for 21 model organisms
2023
E-MSD: an integrated data resource for bioinformatics
2004
SIFTS: Structure Integration with Function, Taxonomy and Sequences resource
2012
SOAP-based services provided by the European Bioinformatics Institute
2005
DNA binding mediates conformational changes and metal ion coordination in the active site of PcrA helicase 1 1Edited by A. R. Fersht
1999
Implementing an X-ray validation pipeline for the Protein Data Bank
2012
The Protein Data Bank in Europe (PDBe): bringing structure to biology
2011
Protein Data Bank (PDB): The Single Global Macromolecular Structure Archive
2017
Crystal Structures of Complexes of PcrA DNA Helicase with a DNA Substrate Indicate an Inchworm Mechanism
1999
SIFTS: updated Structure Integration with Function, Taxonomy and Sequences resource allows 40-fold increase in coverage of structure-based annotations for proteins
2018
The challenge of modeling protein assemblies: the CASP12‐CAPRI experiment
2017
BioJS: an open source JavaScript framework for biological data visualization
2013
Modeling protein‐protein, protein‐peptide, and protein‐oligosaccharide complexes: CAPRI 7th edition
2019