Citation Impact
Citing Papers
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
Phosphorylation of Argonaute proteins affects mRNA binding and is essential for micro RNA ‐guided gene silencing in vivo
2017
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Regulation of microRNA function in animals
2018 Standout
Involvement of Members of the Cadherin Superfamily in Cancer
2009
HIF-1α, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas
2005 StandoutNobel
STAT proteins: From normal control of cellular events to tumorigenesis
2003
The multiple faces of caveolae
2007
TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis
2006 Standout
Regulation of microRNA biogenesis
2014 Standout
SUMOylation of Argonaute-2 regulates RNA interference activity
2015
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
2012 Standout
Functional analyses of phosphorylation events in human Argonaute 2
2015
EMT and Dissemination Precede Pancreatic Tumor Formation
2012 Standout
Acetylation Is Indispensable for p53 Activation
2008
Cellular senescence in aging and age-related disease: from mechanisms to therapy
2015 Standout
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis
2003
Up-regulation of Caveolin Attenuates Epidermal Growth Factor Signaling in Senescent Cells
2000
Ras Proteins Induce Senescence by Altering the Intracellular Levels of Reactive Oxygen Species
1999
Senescence of human fibroblasts induced by oncogenic Raf
1998 Nobel
Vascular Permeability Factor/Vascular Endothelial Growth Factor and the Significance of Microvascular Hyperpermeability in Angiogenesis
1999
Telomere states and cell fates
2000 StandoutNatureNobel
Regulation of MicroRNA Biogenesis: A miRiad of mechanisms
2009
p21/CDKN1A Mediates Negative Regulation of Transcription by p53
2003
Sumoylation of Human Argonaute 2 at Lysine-402 Regulates Its Stability
2014
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
2000 Standout
Angiogenesis in cancer and other diseases
2000 StandoutNature
The Hallmarks of Cancer
2000 Standout
Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts
2011
ROS and p53: A versatile partnership
2008
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Caveolin-1 Mutations in Human Breast Cancer
2006
Structural Foundations of RNA Silencing by Argonaute
2017
Cellular response to oxidative stress: Signaling for suicide and survival*
2002 Standout
Mitochondria, Oxidants, and Aging
2005 Standout
The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP
2007
DNA Damage-Induced Downregulation of Cdc25C Is Mediated by p53 via Two Independent Mechanisms
2004
Phosphorylation of human Argonaute proteins affects small RNA binding
2010
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Argonaute proteins: functional insights and emerging roles
2013
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
The antioxidant function of the p53 tumor suppressor
2005
The dark side of a tumor suppressor: anti-apoptotic p53
2008
E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer
2009
Quantitative functions of Argonaute proteins in mammalian development
2012
Many roads to maturity: microRNA biogenesis pathways and their regulation
2009 Standout
Cellular processing of platinum anticancer drugs
2005 Standout
The widespread regulation of microRNA biogenesis, function and decay
2010 Standout
Phosphorylation of the Human MicroRNA-Generating Complex Mediates MAPK/Erk Signaling
2009
Identification of specific autoantigens in Sjögren's syndrome by SEREX
2005
Caveolin‐1 modulates the activity of the volume‐regulated chloride channel
1999
Poly(ADP-Ribose) Regulates Stress Responses and MicroRNA Activity in the Cytoplasm
2011
Caveolin-1 in mesangial cells suppresses MAP kinase activation and cell proliferation induced by bFGF and PDGF
2004
A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function
2008 Standout
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Caveolin-1 Deficiency (−/−) Conveys Premalignant Alterations in Mammary Epithelia, with Abnormal Lumen Formation, Growth Factor Independence, and Cell Invasiveness
2006
Mutational Heterogeneity in Human Cancers: Origin and Consequences
2009
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Switching and Signaling at the Telomere
2001 StandoutNobel
Transcriptional Repression of Protein Kinase Cα via Sp1 by Wild Type p53 Is Involved in Inhibition of Multidrug Resistance 1 P-Glycoprotein Phosphorylation
2004
The Mammalian UV Response
2000
Absence of Caveolin-1 Sensitizes Mouse Skin to Carcinogen-Induced Epidermal Hyperplasia and Tumor Formation
2003
Stat1-dependent and -independent pathways in IFN-γ-dependent signaling
2002
Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse
1999 StandoutNobel
Regulating the Regulators: Posttranslational Modifications of RNA Silencing Factors
2009
The p53-regulated Cyclin-dependent Kinase Inhibitor, p21 (cip1, waf1, sdi1), Is Not Required for Global Genomic and Transcription-coupled Nucleotide Excision Repair of UV-induced DNA Photoproducts
2001
Posttranscriptional Regulation of MicroRNA Biogenesis in Animals
2010
Comprehensive Identification of Nuclear and Cytoplasmic TNRC6A-Associating Proteins
2017
How might replicative senescence contribute to human ageing?
1999
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
2007 Standout
Cancer-related inflammation
2008 StandoutNature
Characterization of genome-wide p53-binding sites upon stress response
2008
Post-translational modification of p53 in tumorigenesis
2004
A new p38 MAP kinase‐regulated transcriptional coactivator that stimulates p53‐dependent apoptosis
2007
LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength
2016 StandoutNobel
Human Endothelial Cell Life Extension by Telomerase Expression
1999
AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching
2001 StandoutNatureNobel
Telomeres, replicative senescence and human ageing
2001
The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene
1999
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening
1999 StandoutNobel
Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2–mediated heparin-binding EGF signaling in endothelial cells
2011
Oncogenic ras and p53 Cooperate To Induce Cellular Senescence
2002
Telomere length is paternally inherited and is associated with parental lifespan
2007 StandoutNobel
von Hippel-Lindau Disease
2006 StandoutNobel
Caveolin-1 Maintains Activated Akt in Prostate CancerCells through Scaffolding Domain Binding Site Interactions with andInhibition of Serine/Threonine Protein Phosphatases PP1 andPP2A
2003
Caveolin-1 Null (−/−) Mice Show Dramatic Reductions in Life Span
2003
Response of VEGF expression to amino acid deprivation and inducers of endoplasmic reticulum stress.
2002
ATG Systems from the Protein Structural Point of View
2009 StandoutNobel
Rb-Mediated Heterochromatin Formation and Silencing of E2F Target Genes during Cellular Senescence
2003 Standout
Loss of Caveolin-1 Gene Expression Accelerates the Development of Dysplastic Mammary Lesions in Tumor-Prone Transgenic Mice
2003
Making the cut: Protease-mediated regulation of angiogenesis
2006
Matrix Metalloproteinases As Novel Biomarker s and Potential Therapeutic Targets in Human Cancer
2009
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
A bacterial Argonaute with noncanonical guide RNA specificity
2016 StandoutNobel
T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire
2013
Kinase requirements in human cells: III. Altered kinase requirements inVHL−/− cancer cells detected in a pilot synthetic lethal screen
2008 StandoutNobel
Transcriptional control of human p53-regulated genes
2008 Standout
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
2009 StandoutNobel
cis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects
2008 StandoutNobel
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
The Absence of Ser389 Phosphorylation in p53 Affects the Basal Gene Expression Level of Many p53-Dependent Genes and Alters the Biphasic Response to UV Exposure in Mouse Embryonic Fibroblasts
2008
Multistage nanoparticle delivery system for deep penetration into tumor tissue
2011 StandoutNobel
Invasion activating caveolin-1 mutation in human scirrhous breast cancers.
2001
A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation
2001 StandoutNobel
Strategies for the Diversity-Oriented Synthesis of Macrocycles
2019
Combinatorial Peptide Libraries: Mining for Cell-Binding Peptides
2013
The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting
2003
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
2014 StandoutNobel
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1
2004 StandoutNobel
Regulation of mRNA Translation and Stability by microRNAs
2010 Standout
Mechanisms of Endocytosis
2009 Standout
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
p53-mediated apoptosis requires inositol hexakisphosphate kinase-2
2010
Hypoxia Potentiates MicroRNA-Mediated Gene Silencing through Posttranslational Modification of Argonaute2
2011
Generation of Anti-trypanosomal Agents through Concise Synthesis and Structural Diversification of Sesquiterpene Analogues
2011 StandoutNobel
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of Sam W. Lee being referenced
Clonal Selection in Malignant Transformation of Human Fibroblasts Transduced with Defined Cellular Oncogenes
2008
Prolyl 4-hydroxylation regulates Argonaute 2 stability
2008 Nature
Modulation of p53 and p73 levels by cyclin G: implication of a negative feedback regulation
2003
Tumor cell growth inhibition by caveolin re-expression in human breast cancer cells
1998
IFI16 as a Negative Regulator in the Regulation of p53 and p21Waf1
2003
p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53
1999
Role of Pin1 in the Regulation of p53 Stability and p21 Transactivation, and Cell Cycle Checkpoints in Response to DNA Damage
2002
A small molecule that binds Hedgehog and blocks its signaling in human cells
2009
ASC is a Bax adaptor and regulates the p53–Bax mitochondrial apoptosis pathway
2004
Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) delays and induces escape from senescence in human dermal microvascular endothelial cells
1997
H–cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancer
1996
Altered Regulation of Cyclin G in Human Breast Cancer and Its Specific Localization at Replication Foci in Response to DNA Damage in p53+/+ Cells
1999
The negative role of cyclin G in ATM-dependent p53 activation
2004
Hzf Determines Cell Survival upon Genotoxic Stress by Modulating p53 Transactivation
2007
Deep sequencing analysis of phage libraries using Illumina platform
2012
Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-γ target genes
2000
Sustained activation of Ras/Raf/mitogen-activated protein kinase cascade by the tumor suppressor p53
2000
Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53
1997
HB-EGF Is a Potent Inducer of Tumor Growth and Angiogenesis
2004
Tumor Suppressor p53 Is Required To Modulate BRCA1 Expression
2000
Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence
2010
Discoidin Domain Receptor 1 Receptor Tyrosine Kinase Induces Cyclooxygenase-2 and Promotes Chemoresistance through Nuclear Factor-κB Pathway Activation
2006
Identification of a Human VPF/VEGF 3′ Untranslated Region Mediating Hypoxia-induced mRNA Stability
1998
Influence of Induced Reactive Oxygen Species in p53-Mediated Cell Fate Decisions
2003
Membrane-Bound Heparin-Binding Epidermal Growth Factor–Like Growth Factor Regulates E-Cadherin Expression in Pancreatic Carcinoma Cells
2007