Standout Papers
- Limiting the available T cell receptor repertoire modifies acute lymphocytic choriomeningitis virus-induced immunopathology (1994)
- Host response to Sendai virus in mice lacking class II major histocompatibility complex glycoproteins (1995)
- Protection against lethal lymphocytic choriomeningitis virus (LCMV) infection by immunization of mice with an influenza virus containing an LCMV epitope recognized by cytotoxic T lymphocytes (1994)
- Virus-specific CD8+ T-cell responses in mice transgenic for a T-cell receptor beta chain selected at random (1994)
- Lymphocytic choriomeningitis virus induces a chronic wasting disease in mice lacking class I major histocompatibility complex glycoproteins (1993)
- CD8+ T-cell memory to viruses (1994)
- Delayed clearance of Sendai virus in mice lacking class I MHC-restricted CD8+ T cells (1992)
- Divergence between cytotoxic effector function and tumor necrosis factor alpha production for inflammatory CD4+ T cells from mice with Sendai virus pneumonia (1993)
- Temporal loss of the activated L-selectin-low phenotype for virus-specific CD8+ memory T cells. (1995)
- Mice Lacking CD8+ T Cells Develop Greater Numbers of IgA-Producing Cells in Response to a Respiratory Virus Infection (1994)
- Partitioning of responder CD8+ T cells in lymph node and lung of mice with Sendai virus pneumonia by LECAM-1 and CD45RB phenotype (1993)
- Extent of γδ T cell involvement in the pneumonia caused by sendai virus (1992)
- Subverting lymph node trafficking by treatment with the Mel-14 monoclonal antibody to L-selectin does not prevent an effective host response to Sendai virus (1995)
- Virus-specific CD8+ T-cell memory determined by clonal burst size (1994)
- Recruitment and proliferation of CD8+ T cells in respiratory virus infections. (1995)
- Clearance of Sendai virus by CD8+ T cells requires direct targeting to virus‐infected epithelium (1995)
Citation Impact
Citing Papers
HCV Persistence and Immune Evasion in the Absence of Memory T Cell Help
2003 StandoutScienceNobel
Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection
2005
Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program
2007 StandoutNobel
Bacterial CpG-DNA activates dendritic cellsin vivo: T helper cell-independent cytotoxic T cell responses to soluble proteins
2000
Nucleotide Oligomerization Binding Domain-Like Receptor Signaling Enhances Dendritic Cell-Mediated Cross-Priming In Vivo
2009 StandoutNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
IRF-7 is the master regulator of type-I interferon-dependent immune responses
2005 StandoutNature
Efficient T Cell Activation via a Toll-Interleukin 1 Receptor-Independent Pathway
2006 StandoutNobel
Long–term restoration of immunity against Epstein–Barr virus infection by adoptive transfer of gene–modified virus–specific T lymphocytes
1996
Immunosuppressive networks in the tumour environment and their therapeutic relevance
2005 Standout
Regulation of the type I IFN induction: a current view
2005
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
CD8 lethargy in the absence of CD4 help
2002
Type I Interferons in Host Defense
2006
Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function
2005
Toll-like receptor control of the adaptive immune responses
2004 Standout
Superantigen Shock In Mice With An Inapparent Viral Infection
1994 StandoutNobel
Evasion of Host Immune Responses by Tumours and Viruses
2007 Nobel
Cytotoxic T Cell Effector and Memory Function in Viral Immunity
1996 StandoutNobel
Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer
2023
T and B memory cells
1994
Virus infections in mice with targeted gene disruptions
1993 StandoutNobel
Modulating vaccine responses with dendritic cells and Toll‐like receptors
2004
Translating Innate Immunity into Immunological Memory: Implications for Vaccine Development
2006
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Characterization of Liver T–Cell Receptor γδ+ T Cells Obtained From Individuals Chronically Infected With Hepatitis C Virus (Hcv): Evidence for These T Cells Playing A Role in the Liver Pathology Associated With Hcv Infections
2001 StandoutNobel
Dendritic cells: a journey from laboratory to clinic
2003
Toll-like receptor 3 promotes cross-priming to virus-infected cells
2005 Nature
Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory
2001
Stimulation of naive and memory T cells by cytokines
1999
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Vaccines against intracellular infections requiring cellular immunity
2000 Nature
Interferon signalling network in innate defence
2006
Helping the CD8+ T-cell response
2004
Cell-mediated cytotoxicity
1993 StandoutNobel
Restoring function in exhausted CD8 T cells during chronic viral infection
2005 StandoutNatureNobel
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Cross‐presentation, dendritic cell subsets, and the generation of immunity to cellular antigens
2004
Poly(I:C) is an effective adjuvant for antibody and multi-functional CD4+ T cell responses to Plasmodium falciparum circumsporozoite protein (CSP) and αDEC-CSP in non human primates
2010 StandoutNobel
Cancer Immunotherapy by Dendritic Cells
2008
TLR3 in antiviral immunity: key player or bystander?
2005
An indispensable role of type-1 IFNs for inducing CTL-mediated complete eradication of established tumor tissue by CpG-liposome co-encapsulated with model tumor antigen
2006
A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell
1998 StandoutNature
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
1996 StandoutNatureNobel
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Inhibition of ubiquitin/proteasome-dependent protein degradation by the Gly-Ala repeat domain of the Epstein–Barr virus nuclear antigen 1
1997 StandoutNobel
Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function
1998 Standout
Selection of a single amino acid substitution in the hemagglutinin molecule by chicken eggs can render influenza A virus (H3) candidate vaccine ineffective
1995
Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant
2009 StandoutNobel
Induction of cytokines in mice with parainfluenza pneumonia
1995 StandoutNobel
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates
2011 StandoutNobel
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice
1994
Direct Stimulation of T Cells by Type I IFN Enhances the CD8+ T Cell Response during Cross-Priming
2006
Plasmacytoid DCs help lymph node DCs to induce anti-HSV CTLs
2005
Effector and Memory CTL Differentiation
2006
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8 + T cells in a spectrum of human MHC I haplotypes
2007 StandoutNobel
HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+T cell responses in nonhuman primates
2005
Phenotypic Analysis of Antigen-Specific T Lymphocytes
1996 StandoutScience
Immune CD4+ T cells promote the clearance of influenza virus from major histocompatibility complex class II -/- respiratory epithelium
1996 StandoutNobel
Plasmacytoid predendritic cells initiate psoriasis through interferon-α production
2005
Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN-α/β on antigen cross-presentation
2006 StandoutNobel
Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A
2011 StandoutNobel
Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant.
1995 StandoutNobel
Activation of cytokine genes in T cells during primary and secondary murine influenza pneumonia.
1993 StandoutNobel
TYPE I INTERFERONS (α/β) IN IMMUNITY AND AUTOIMMUNITY
2004 StandoutNobel
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
Epitope focusing in the primary cytotoxic T cell response to Epstein-Barr virus and its relationship to T cell memory.
1996
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
IPC: Professional Type 1 Interferon-Producing Cells and Plasmacytoid Dendritic Cell Precursors
2004
Patients with chronic hepatitis C have circulating cytotoxic T cells which recognize hepatitis C virus-encoded peptides binding to HLA-A2.1 molecules
1995 StandoutNobel
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
Cytotoxic T lymphocyte response to a wild type hepatitis B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope.
1994
Immunization with HIV-1 Gag Protein Conjugated to a TLR7/8 Agonist Results in the Generation of HIV-1 Gag-Specific Th1 and CD8+ T Cell Responses
2005
Anergy and exhaustion are independent mechanisms of peripheral T cell tolerance.
1995
Induction of Bystander T Cell Proliferation by Viruses and Type I Interferon in Vivo
1996 Science
Concurrent production of interleukin-2, interleukin-10, and gamma interferon in the regional lymph nodes of mice with influenza pneumonia
1994 StandoutNobel
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
2006 StandoutNobel
Variegation of the Immune Response with Dendritic Cells and Pathogen Recognition Receptors
2005
Differential antigen burden modulates the gamma interferon but not the immunoglobulin response in mice that vary in susceptibility to Sendai virus pneumonia
1995 StandoutNobel
Dendritic cells cross-present HIV antigens from live as well as apoptotic infected CD4 + T lymphocytes
2004
Respiratory virus infection of mice provokes a permanent humoral immune response
1994
Cutting Edge: Type I IFNs Provide a Third Signal to CD8 T Cells to Stimulate Clonal Expansion and Differentiation
2005
Type I Interferons Keep Activated T Cells Alive
1999
Progressive loss of CD8+ T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells.
1996 StandoutNobel
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
The B-cell response in lymphoid tissue of mice immunized with various antigenic forms of the influenza virus hemagglutinin
1995 StandoutNobel
Altered peptidase and viral-specific T cell response in LMP2 mutant mice
1994 StandoutNobel
Selective response of gamma delta T-cell hybridomas to orthomyxovirus-infected cells
1996 StandoutNobel
Immunological Memory and Protective Immunity: Understanding Their Relation
1996 StandoutScience
Adjuvant-Enhanced Antibody Responses in the Absence of Toll-Like Receptor Signaling
2006 StandoutScienceNobel
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Nonproliferating Bystander CD4+ T Cells Lacking Activation Markers Support HIV Replication During Immune Activation
2001 StandoutNobel
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
Analysis of the primary T-cell response to Sendai virus infection in C57BL/6 mice: CD4+ T-cell recognition is directed predominantly to the hemagglutinin-neuraminidase glycoprotein
1994
Works of Sam Hou being referenced
Extent of γδ T cell involvement in the pneumonia caused by sendai virus
1992 StandoutNobel
Mice Lacking CD8+ T Cells Develop Greater Numbers of IgA-Producing Cells in Response to a Respiratory Virus Infection
1994 StandoutNobel
Limiting the available T cell receptor repertoire modifies acute lymphocytic choriomeningitis virus-induced immunopathology
1994 StandoutNobel
Clearance of Sendai virus by CD8+ T cells requires direct targeting to virus‐infected epithelium
1995 StandoutNobel
Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon
2003
Lymphocytic choriomeningitis virus induces a chronic wasting disease in mice lacking class I major histocompatibility complex glycoproteins
1993 StandoutNobel
CD8+ T-cell memory to viruses
1994 StandoutNobel
Virus-specific CD8+ T-cell memory determined by clonal burst size
1994 StandoutNatureNobel
Divergence between cytotoxic effector function and tumor necrosis factor alpha production for inflammatory CD4+ T cells from mice with Sendai virus pneumonia
1993 StandoutNobel
Temporal loss of the activated L-selectin-low phenotype for virus-specific CD8+ memory T cells.
1995 StandoutNobel
Recruitment and proliferation of CD8+ T cells in respiratory virus infections.
1995 StandoutNobel
Host response to Sendai virus in mice lacking class II major histocompatibility complex glycoproteins
1995 StandoutNobel
Delayed clearance of Sendai virus in mice lacking class I MHC-restricted CD8+ T cells
1992 StandoutNobel
Partitioning of responder CD8+ T cells in lymph node and lung of mice with Sendai virus pneumonia by LECAM-1 and CD45RB phenotype
1993 StandoutNobel
Protection against lethal lymphocytic choriomeningitis virus (LCMV) infection by immunization of mice with an influenza virus containing an LCMV epitope recognized by cytotoxic T lymphocytes
1994 StandoutNobel
Virus-specific CD8+ T-cell responses in mice transgenic for a T-cell receptor beta chain selected at random
1994 StandoutNobel