Standout Papers
- Relationships between G1 arrest and stability of the p53 and p21Cip1/Waf1 proteins following gamma-irradiation of human lymphoma cells. (1995)
- Inactivation of p53 increases the cytotoxicity of camptothecin in human colon HCT116 and breast MCF-7 cancer cells. (1997)
Citation Impact
Citing Papers
TFEB Links Autophagy to Lysosomal Biogenesis
2011 StandoutScience
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
2009 StandoutScience
Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes
2003 StandoutScience
Breast and Ovarian Cancer Risks Due to Inherited Mutations in BRCA1 and BRCA2
2003 StandoutScience
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
Carbenoxolone Blocks Endotoxin-Induced Protein Kinase R (PKR) Activation and High Mobility Group Box 1 (HMGB1) Release
2013
Gene expression profiling predicts clinical outcome of breast cancer
2002 StandoutNature
The DNA-damage response in human biology and disease
2009 StandoutNature
Requirement of Stat3 signaling for HGF/SF-Met mediated tumorigenesis
2002
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
2005 StandoutNature
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Stromal fibroblasts in cancer initiation and progression
2004 StandoutNature
Estrogen Receptors: How Do They Signal and What Are Their Targets
2007 Standout
Cancer chemoprevention with dietary phytochemicals
2003 Standout
Molecular Cloning and Characterization of PELP1, a Novel Human Coregulator of Estrogen Receptor α
2001
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
2009 StandoutNature
Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 corepressor
2000
Met/HGF receptor modulates bcl-w expression and inhibits apoptosis in human colorectal cancers
2000
Epigallocatechin-3-Gallate (EGCG), a Green Tea Polyphenol, Stimulates Hepatic Autophagy and Lipid Clearance
2014
Cell-cycle checkpoints and cancer
2004 StandoutNature
Role of the SCFSkp2 Ubiquitin Ligase in the Degradation of p21Cip1 in S Phase
2003 StandoutNobel
P53 and radiation responses
2003
Intracellular accumulation and immunological properties of fluorescent gold nanoclusters in human dendritic cells
2014
Basic mechanisms of high‐risk human papillomavirus‐induced carcinogenesis: Roles of E6 and E7 proteins
2007
A microRNA component of the p53 tumour suppressor network
2007 StandoutNature
Scaffold attachment factors SAFB1 and SAFB2: Innocent bystanders or critical players in breast tumorigenesis?
2003
Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology
2015 Standout
MICoA, a Novel Metastasis-associated Protein 1 (MTA1) Interacting Protein Coactivator, Regulates Estrogen Receptor-α Transactivation Functions
2003
An imaging-guided platform for synergistic photodynamic/photothermal/chemo-therapy with pH/temperature-responsive drug release
2015
Regulation of Nuclear Receptor Transcriptional Activity by a Novel DEAD Box RNA Helicase (DP97)
2003
Bio-NCs – the marriage of ultrasmall metal nanoclusters with biomolecules
2014
Modulation of oxidative stress as an anticancer strategy
2013 Standout
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Epigallocatechin-gallate (EGCG) regulates autophagy in human retinal pigment epithelial cells: A potential role for reducing UVB light-induced retinal damage
2013
Lysine acetylation and the bromodomain: a new partnership for signaling
2004
BRCA1-IRIS regulates cyclin D1 expression in breast cancer cells
2006
Cells on chips
2006 StandoutNature
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
2009 StandoutNature
The HIN domain of IFI-200 proteins consists of two OB folds
2004
The hepatocyte growth factor/Met pathway controls proliferation and apoptosis in multiple myeloma
2003
Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity
2015 Standout
Decoding ALS: from genes to mechanism
2016 StandoutNature
The cytoprotective role of the Keap1–Nrf2 pathway
2011
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation
2007
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
2007 StandoutNature
Enhancing Radiotherapy by Lipid Nanocapsule-Mediated Delivery of Amphiphilic Gold Nanoparticles to Intracellular Membranes
2014
Modifiers of risk of hereditary breast and ovarian cancer
2002
Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
2009
Targeting the tumor and its microenvironment by a dual-function decoy Met receptor
2004
Balancing the Rate of Cluster Growth and Etching for Gram‐Scale Synthesis of Thiolate‐Protected Au25 Nanoclusters with Atomic Precision
2014
limma powers differential expression analyses for RNA-sequencing and microarray studies
2015 Standout
Histone deacetylase inhibitors: molecular mechanisms of action
2007
Met, metastasis, motility and more
2003 Standout
Epigallocatechin Gallate (EGCG) Stimulates Autophagy in Vascular Endothelial Cells
2013
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Microfluidic chips for clinical and forensic analysis
2002
The Hallmarks of Aging
2013 Standout
Tumor suppressor genes and ROS: complex networks of interactions
2011
Cancer Susceptibility and the Functions of BRCA1 and BRCA2
2002
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Principles of Tumor Suppression
2004
Topoisomerase I inhibitors: camptothecins and beyond
2006 Standout
Metal Nanoclusters: Applications in Environmental Monitoring and Cancer Therapy
2015
BRCA1 down‐regulates cellular levels of reactive oxygen species
2009
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
2003
Repair of Topoisomerase I‐Mediated DNA Damage
2006
Core–Shell MnSe@Bi2Se3 Fabricated via a Cation Exchange Method as Novel Nanotheranostics for Multimodal Imaging and Synergistic Thermoradiotherapy
2015
How Can We Understand Au8 Cores and Entangled Ligands of Selenolate- and Thiolate-Protected Gold Nanoclusters Au24(ER)20 and Au20(ER)16 (E = Se, S; R = Ph, Me)? A Theoretical Study
2015
Ubiquitination of p53 and p21 Is Differentially Affected by Ionizing and UV Radiation
1997
Atomically Precise Colloidal Metal Nanoclusters and Nanoparticles: Fundamentals and Opportunities
2016 Standout
Regulation of p53 Function
2001
Recent advances in the synthesis, characterization, and biomedical applications of ultrasmall thiolated silver nanoclusters
2014
In vivo targeting of SF/HGF and c‐met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis
2001
Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation
2011 StandoutNobel
Optical Properties of 2-Methacryloyloxyethyl Phosphorylcholine-Protected Au4 Nanoclusters and Their Fluorescence Sensing of C-Reactive Protein
2015
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Membrane proteomics of phagosomes suggests a connection to autophagy
2008 StandoutNobel
HET/SAF-B overexpression causes growth arrest and multinuclearity and is associated with aneuploidy in human breast cancer.
2000
Presentation matters: Identity of gold nanocluster capping agent governs intracellular uptake and cell metabolism
2014
Generation of Singlet Oxygen by Photoexcited Au25(SR)18 Clusters
2014
Growth of Highly Fluorescent Polyethylene Glycol- and Zwitterion-Functionalized Gold Nanoclusters
2013
Exploring Interfacial Events in Gold-Nanocluster-Sensitized Solar Cells: Insights into the Effects of the Cluster Size and Electrolyte on Solar Cell Performance
2015
Organizing Principles of Mammalian Nonsense-Mediated mRNA Decay
2013
Optical properties of nanoalloys
2015
Au25cluster functionalized metal–organic nanostructures for magnetically targeted photodynamic/photothermal therapy triggered by single wavelength 808 nm near-infrared light
2015
AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination
2009 StandoutNobel
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Perfluorocarbon‐Loaded Hollow Bi2Se3 Nanoparticles for Timely Supply of Oxygen under Near‐Infrared Light to Enhance the Radiotherapy of Cancer
2016
Mechanisms of Estrogen Action
2001 Standout
In Vivo Analysis of Biodegradable Liposome Gold Nanoparticles as Efficient Agents for Photothermal Therapy of Cancer
2015
BRCA1 mediates ligand-independent transcriptional repression of the estrogen receptor
2001
Gold Nanomaterials at Work in Biomedicine
2015
Reversible Size Control of Silver Nanoclusters via Ligand-Exchange
2015
Coregulator Function: A Key to Understanding Tissue Specificity of Selective Receptor Modulators
2004
Ultrasmall Biocompatible WO3−x Nanodots for Multi‐Modality Imaging and Combined Therapy of Cancers
2016
The Nucleation and Growth Mechanism of Thiolate-Protected Au Nanoclusters
2015
Precise synthesis, functionalization and application of thiolate-protected gold clusters
2016
Gold–Thiolate Ring as a Protecting Motif in the Au20(SR)16 Nanocluster and Implications
2014
Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal models
2001
Antisense Bcl-xl down-regulation switches the response to topoisomerase I inhibition from senescence to apoptosis in colorectal cancer cells, enhancing global cytotoxicity.
2003
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Multifunctional Au nanoclusters for targeted bioimaging and enhanced photodynamic inactivation of Staphylococcus aureus
2015
Significance analysis of microarrays applied to the ionizing radiation response
2001 Standout
Topoisomerase I inhibitors: selectivity and cellular resistance
1999
Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways
2000
Neoantigens in cancer immunotherapy
2015 StandoutScience
Clearance Pathways and Tumor Targeting of Imaging Nanoparticles
2015
Au@MnS@ZnS Core/Shell/Shell Nanoparticles for Magnetic Resonance Imaging and Enhanced Cancer Radiation Therapy
2016
Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G 1 /S checkpoint activation in response to DNA damage
2001
A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling
2005 StandoutScience
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
Rhenium‐188 Labeled Tungsten Disulfide Nanoflakes for Self‐Sensitized, Near‐Infrared Enhanced Radioisotope Therapy
2016
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Cancer immunotherapy using checkpoint blockade
2018 StandoutScience
Gold Nanoclusters Doped with64Cu for CXCR4 Positron Emission Tomography Imaging of Breast Cancer and Metastasis
2016
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Ultrasmall Biocompatible Bi2Se3 Nanodots for Multimodal Imaging-Guided Synergistic Radiophotothermal Therapy against Cancer
2016
Catalase‐Loaded TaOx Nanoshells as Bio‐Nanoreactors Combining High‐Z Element and Enzyme Delivery for Enhancing Radiotherapy
2016
p53-Mediated DNA Repair Responses to UV Radiation: Studies of Mouse Cells Lacking p53, p21, and/orgadd45 Genes
2000
Atomically Precise Clusters of Noble Metals: Emerging Link between Atoms and Nanoparticles
2017 Standout
Autophagy in Health and Disease: A Double-Edged Sword
2004 StandoutScience
Works of Saijun Fan being referenced
BRCA1 Induces Antioxidant Gene Expression and Resistance to Oxidative Stress
2004
BRCA1 and BRCA2 as molecular targets for phytochemicals indole-3-carbinol and genistein in breast and prostate cancer cells
2006
p53-Independent Down-Regulation of Mdm2 in Human Cancer Cells Treated with Adriamycin
2000
Role of direct interaction in BRCA1 inhibition of estrogen receptor activity
2001
Scatter factor protects epithelial and carcinoma cells against apoptosis induced by DNA-damaging agents
1998
Structural determinants of the BRCA1 : estrogen receptor interaction
2005
Tanshinone IIA sodium sulfonate facilitates endocytic HMGB1 uptake
2012
The cytokine hepatocyte growth factor/scatter factor inhibits apoptosis and enhances DNA repair by a common mechanism involving signaling through phosphatidyl inositol 3′ kinase
2000
EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages
2011
Abrogation of p53 Function Affects gadd Gene Responses to DNA Base-Damaging Agents and Starvation
1996
BRCA1 regulation of transcription
2005
BRCA1 gene in breast cancer
2003
Passing through the renal clearance barrier: toward ultrasmall sizes with stable ligands for potential clinical applications
2014
In vivo renal clearance, biodistribution, toxicity of gold nanoclusters
2012
BRCA1 Interaction with Human Papillomavirus Oncoproteins
2005
Enhanced Tumor Accumulation of Sub‐2 nm Gold Nanoclusters for Cancer Radiation Therapy
2013
Disruption of BRCA1 LXCXE motif alters BRCA1 functional activity and regulation of RB family but not RB protein binding
2001
Suppression of breast cancer invasion and migration by indole-3-carbinol: associated with up-regulation of BRCA1 and E-cadherin/catenin complexes
2000
Capillary and Microchip Electrophoresis for Rapid Detection of Known Mutations by Combining Allele-specific DNA Amplification with Heteroduplex Analysis
2001
The Breast Cancer Susceptibility Gene BRCA1 Regulates Progesterone Receptor Signaling in Mammary Epithelial Cells
2005
Relationships between G1 arrest and stability of the p53 and p21Cip1/Waf1 proteins following gamma-irradiation of human lymphoma cells.
1995 StandoutNobel
BRCA1 Inhibition of Estrogen Receptor Signaling in Transfected Cells
1999 Science
Inactivation of p53 increases the cytotoxicity of camptothecin in human colon HCT116 and breast MCF-7 cancer cells.
1997 StandoutNobel
Ultrasmall Au10−12(SG)10−12 Nanomolecules for High Tumor Specificity and Cancer Radiotherapy
2014
The Multisubstrate Adapter Gab1 Regulates Hepatocyte Growth Factor (Scatter Factor)–c-Met Signaling for Cell Survival and DNA Repair
2001
p300 Modulates the BRCA1 inhibition of estrogen receptor activity.
2002
Storage of Gold Nanoclusters in Muscle Leads to their Biphasic in Vivo Clearance
2014
Acetylation of Androgen Receptor Enhances Coactivator Binding and Promotes Prostate Cancer Cell Growth
2003