Citation Impact
Citing Papers
Pretreatment Epidermal Growth Factor Receptor ( EGFR ) T790M Mutation Predicts Shorter EGFR Tyrosine Kinase Inhibitor Response Duration in Patients With Non–Small-Cell Lung Cancer
2012
The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP
2008 Standout
Quantitative Detection of EGFR Mutations in Circulating Tumor DNA Derived from Lung Adenocarcinomas
2011
Oncogenic Activity of Epidermal Growth Factor Receptor Kinase Mutant Alleles Is Enhanced by the T790M Drug Resistance Mutation
2007
Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in EGFR-Mutant Lung Cancer: Distinct Natural History of Patients with Tumors Harboring the T790M Mutation
2010
Phase III Study of Afatinib or Cisplatin Plus Pemetrexed in Patients With Metastatic Lung Adenocarcinoma With EGFR Mutations
2013 Standout
Elevated CRAF as a Potential Mechanism of Acquired Resistance to BRAF Inhibition in Melanoma
2008
Genetic and Functional Studies Implicate HIF1 α as a 14q Kidney Cancer Suppressor Gene
2011 StandoutNobel
Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival
2014 StandoutNobel
Co-incidence of RCC-susceptibility polymorphisms with HIF cis-acting sequences supports a pathway tuning model of cancer
2019 StandoutNobel
On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models
2016 StandoutNatureNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
ERBB receptors and cancer: the complexity of targeted inhibitors
2005 Standout
Emergence of Epidermal Growth Factor Receptor T790M Mutation during Chronic Exposure to Gefitinib in a Non–Small Cell Lung Cancer Cell Line
2007
EGFR Antagonists in Cancer Treatment
2008 Standout
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
Involvement of Members of the Cadherin Superfamily in Cancer
2009
IDH1andIDH2Mutations in Gliomas
2009 Standout
EGFR mutation status in tumour-derived DNA from pleural effusion fluid is a practical basis for predicting the response to gefitinib
2006
A view on drug resistance in cancer
2019 StandoutNature
Novel mutant-selective EGFR kinase inhibitors against EGFR T790M
2009 StandoutNature
Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma
2009 Standout
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
The biology and management of non-small cell lung cancer
2018 StandoutNature
Epidermal growth factor receptor mutations in lung cancer
2007 Standout
Lung Cancer
2008 Standout
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
Cancer drug resistance: an evolving paradigm
2013 Standout
Malignant astrocytic glioma: genetics, biology, and paths to treatment
2007 Standout
Protein factors in pre-mRNA 3′-end processing
2007
BAC array CGH distinguishes mutually exclusive alterations that define clinicogenetic subtypes of gliomas
2007
Radiomics: Images Are More than Pictures, They Are Data
2015 Standout
Osimertinib or Platinum–Pemetrexed in EGFR T790M–Positive Lung Cancer
2016 Standout
The biology and function of fibroblasts in cancer
2016 Standout
The mini-driver model of polygenic cancer evolution
2015 StandoutNobel
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer
2013 Standout
How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine
2010
Drug resistance analysis of gefitinib-targeted therapy in non-small cell lung cancer
2016
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
2010 StandoutNature
The molecular biology of head and neck cancer
2010 Standout
Genetic Patterns in Head and Neck Cancers That Contain or Lack Transcriptionally Active Human Papillomavirus
2004
The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
2016 Standout
Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)–mediated induction of the long noncoding RNA NICI
2019 StandoutNobel
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Sequence-specific inhibition of microRNA via CRISPR/CRISPRi system
2014
Population-Based Studies on Incidence, Survival Rates, and Genetic Alterations in Astrocytic and Oligodendroglial Gliomas
2005
Cell-free nucleic acids as biomarkers in cancer patients
2011 Standout
Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer
2013 StandoutNobel
Development of New Mouse Lung Tumor Models Expressing EGFR T790M Mutants Associated with Clinical Resistance to Kinase Inhibitors
2007
The ING gene family in the regulation of cell growth and tumorigenesis
2008
Detection of Mutations in EGFR in Circulating Lung-Cancer Cells
2008
A Translational View of the Molecular Pathogenesis of Lung Cancer
2007
Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia
2014
Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression
2012 StandoutNobel
Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer
2010 Standout
A Platform for Rapid Detection of Multiple Oncogenic Mutations With Relevance to Targeted Therapy in Non–Small-Cell Lung Cancer
2011
Heterogeneous Effects of Direct Hypoxia Pathway Activation in Kidney Cancer
2015 StandoutNobel
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
2014 Standout
A guide to deep learning in healthcare
2018 Standout
Genome-wide DNA copy number alterations in head and neck squamous cell carcinomas with or without oncogene-expressing human papillomavirus
2005
Primary brain tumours in adults
2012 Standout
Intravital Imaging Reveals How BRAF Inhibition Generates Drug-Tolerant Microenvironments with High Integrin β1/FAK Signaling
2015
Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach
2014 Standout
Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex
2009 StandoutNobel
A Noninvasive System for Monitoring Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors with Plasma DNA
2011
Regulatory networks defining EMT during cancer initiation and progression
2013 Standout
The MYST family of histone acetyltransferases and their intimate links to cancer
2007
Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer
2010
FY Is an RNA 3′ End-Processing Factor that Interacts with FCA to Control the Arabidopsis Floral Transition
2003
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA
2012
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Specific EGFR Mutations Predict Treatment Outcome of Stage IIIB/IV Patients With Chemotherapy-Naive Non–Small-Cell Lung Cancer Receiving First-Line Gefitinib Monotherapy
2008
First-Line Gefitinib in Patients With Advanced Non–Small-Cell Lung Cancer Harboring SomaticEGFRMutations
2008
Cancer Genome Landscapes
2013 StandoutScience
Genetic Pathways to Glioblastoma
2004
Liquid Biopsies: Genotyping Circulating Tumor DNA
2014 Standout
Single-Molecule Detection of Epidermal Growth Factor Receptor Mutations in Plasma by Microfluidics Digital PCR in Non–Small Cell Lung Cancer Patients
2009
Genetic Signatures of HPV-related and Unrelated Oropharyngeal Carcinoma and Their Prognostic Implications
2009
Works of Sachio Ito being referenced
Positive correlation between allelic loss at chromosome 14q24-31 and poor prognosis of patients with renal cell carcinoma
2004
Prognostic Value of Loss of Heterozygosity around three Candidate Tumor Suppressor Genes on Chromosome 10q in Astrocytomas
2002
A Novel WD40 Repeat Protein, WDC146, Highly Expressed during Spermatogenesis in a Stage-Specific Manner
2001
Identification of direct targets for the miR‐17‐92 cluster by proteomic analysis
2011
Genome-Wide Analyses on Loss of Heterozygosity in Head and Neck Squamous Cell Carcinomas
2003
Allelic loss and reduced expression of the ING3, a candidate tumor suppressor gene at 7q31, in human head and neck cancers
2002
EGFR mutation status in pleural fluid predicts tumor responsiveness and resistance to gefitinib
2007
Prevalent hyper-methylation of the CDH13 gene promoter in malignant B cell lymphomas
2004
Presence ofEpidermal Growth Factor ReceptorGene T790M Mutation as a Minor Clone in Non–Small Cell Lung Cancer
2006
Loss of heterozygosity on chromosome 10q associated with malignancy and prognosis in astrocytic tumors, and discovery of novel loss regions
2004
Highly frequent allelic loss of chromosome 6q16-23 in osteosarcoma: Involvement of cyclin C in osteosarcoma
2006
Detection ofEGFRGene Mutation in Lung Cancer by Mutant-Enriched Polymerase Chain Reaction Assay
2006