Citation Impact
Citing Papers
Preferential induction of apoptosis for primary human leukemic stem cells
2002
PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors
2003 StandoutScience
A Novel Germline Variant in CSF3R Reduces N-Glycosylation and Exerts Potent Oncogenic Effects in Leukemia
2018 StandoutNobel
Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet
2009 Standout
Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a cancer and leukemia group B study.
2001
β-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation
2009 StandoutNobel
A new and recurrent activating length mutation in exon 20 of the FLT3 gene in acute myeloid leukemia
2002
Mislocalized Activation of Oncogenic RTKs Switches Downstream Signaling Outcomes
2009
Cyclin D1 suppresses retinoblastoma protein-mediated inhibition of TAFII250 kinase activity
2000 StandoutNobel
Ordering S phase and M phase in the cell cycle
1994 StandoutNobel
The role of FLT3 in haematopoietic malignancies
2003
A view on drug resistance in cancer
2019 StandoutNature
IL-13 Receptor α2 Promotes Epithelial Cell Regeneration From Radiation–Induced Small Intestinal Injury in Mice
2006
Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs
2004
The Structural Basis for Autoinhibition of FLT3 by the Juxtamembrane Domain
2004
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Activation of tyrosine kinases by mutation of the gatekeeper threonine
2008
N6-methyladenosine Modulates Messenger RNA Translation Efficiency
2015 Standout
Interleukin-4 and lnterleukin-13: Their Similarities and Discrepancies
1998
A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?
2011 Standout
Sunitinib versus Interferon Alfa in Metastatic Renal-Cell Carcinoma
2007 Standout
p65cdc18 Plays a major role controlling the initiation of DNA replication in fission yeast
1995 StandoutNobel
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
AU-rich elements and associated factors: are there unifying principles?
2005
Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial
2006 Standout
Role of the retinoblastoma protein in the pathogenesis of human cancer.
1997 StandoutNobel
miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades
2011 Standout
Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway
1998
Cancer genes and the pathways they control
2004 Standout
Single Cell Profiling of Potentiated Phospho-Protein Networks in Cancer Cells
2004
Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
2007 Standout
The widespread regulation of microRNA biogenesis, function and decay
2010 Standout
Immunity, Inflammation, and Cancer
2010 Standout
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
2005 Standout
Potent Prostaglandin A1 Analogs That Suppress Tumor Cell Growth through Induction of p21 and Reduction of Cyclin E
1998 StandoutNobel
U1 snRNP regulates cancer cell migration and invasion in vitro
2020 Standout
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Alternative Activation of Macrophages: Mechanism and Functions
2010 Standout
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
2013 Standout
Macrophage plasticity and polarization: in vivo veritas
2012 Standout
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
2014 Standout
Inhibitors of mammalian G1 cyclin-dependent kinases.
1995 Standout
TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth
2006 Standout
Cyclins and cancer II: Cyclin D and CDK inhibitors come of age
1994 Standout
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
2010 StandoutNature
Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells
2009
Wnt signalling in stem cells and cancer
2005 StandoutNature
Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA
2015 StandoutNobel
Genetic Alterations of Cyclins, Cyclin-Dependent Kinases, and Cdk Inhibitors in Human Cancer
1996
IL-33, an Interleukin-1-like Cytokine that Signals via the IL-1 Receptor-Related Protein ST2 and Induces T Helper Type 2-Associated Cytokines
2005 Standout
Functional Characterization of FLT3 Receptor Signaling Deregulation in Acute Myeloid Leukemia by Single Cell Network Profiling (SCNP)
2010
Defects in the Ubiquitin Pathway Induce Caspase-independent Apoptosis Blocked by Bcl-2
1998 StandoutNobel
Revised Recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia
2003 Standout
β-Arrestin2 mediates the initiation and progression of myeloid leukemia
2012 StandoutNobel
Prognostic relevance of FLT3-TKD mutations in AML: the combination matters—an analysis of 3082 patients
2007
Identification of a Cyclin-cdk2 Recognition Motif Present in Substrates and p21-Like Cyclin-Dependent Kinase Inhibitors
1996 StandoutNobel
Anti-cancer-prostaglandin-induced cell-cycle arrest and its modulation by an inhibitor of the ATP-dependent glutathione S-conjugate export pump (GS-X pump)
1998 StandoutNobel
Phenotypic characterization of human colorectal cancer stem cells
2007 Standout
Identification of a novel type of ITD mutations located in nonjuxtamembrane domains of the FLT3 tyrosine kinase receptor
2008
Activation of Wnt signalling in acute myeloid leukemia by induction of Frizzled-4
1992
Translocation Products in Acute Myeloid Leukemia Activate the Wnt Signaling Pathway in Hematopoietic Cells
2004
Single-agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia
2004
Cancer Cell Cycles
1996 StandoutScience
The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
2009 Standout
Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia
2012
After chronic myelogenous leukemia: tyrosine kinase inhibitors in other hematologic malignancies
2004
The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia
2007
Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis
2002
Retinoblastoma Protein Contains a C-terminal Motif That Targets It for Phosphorylation by Cyclin-cdk Complexes
1999 StandoutNobel
Insertion of FLT3 internal tandem duplication in the tyrosine kinase domain-1 is associated with resistance to chemotherapy and inferior outcome
2009
A FLT3-targeted tyrosine kinase inhibitor is cytotoxic to leukemia cells in vitro and in vivo
2002
A phase 1 study of SU11248 in the treatment of patients with refractory or resistant acute myeloid leukemia (AML) or not amenable to conventional therapy for the disease
2005
Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum
2011 StandoutScience
Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: a study of the AML Study Group Ulm
2002
Breast cancer instructs dendritic cells to prime interleukin 13–secreting CD4+ T cells that facilitate tumor development
2007
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
2003
The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway
1999 Standout
Heterogeneous Patterns of FLT3 Asp835 Mutations in Relapsed de Novo Acute Myeloid Leukemia
2004
FLT3 expressing leukemias are selectively sensitive to inhibitors of the molecular chaperone heat shock protein 90 through destabilization of signal transduction-associated kinases.
2003
Inhibition of G1 Cyclin-Dependent Kinase Activity during Growth Arrest of Human Breast Carcinoma Cells by Prostaglandin A2
1996
A maize cDNA encoding a member of the retinoblastoma protein family: involvement in endoreduplication.
1996 StandoutNobel
GENETICS OF MYELOID LEUKEMIAS
2002
Regulation of mRNA Translation and Stability by microRNAs
2010 Standout
IL-13 Effector Functions
2003
The FLT3 Internal Tandem Duplication Mutation Prevents Apoptosis in Interleukin-3-Deprived BaF3 Cells Due to Protein Kinase A and Ribosomal S6 Kinase 1–Mediated BAD Phosphorylation at Serine 112
2005
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
2006 StandoutScience
Infection of primary cells by adeno-associated virus type 2 results in a modulation of cell cycle-regulating proteins
1997 StandoutNobel
Works of S Serve being referenced
Inhibition of proliferation and clonal growth of human breast cancer cells by interleukin 13.
1996
A truncated cyclin D1 gene encodes a stable mRNA in a human breast cancer cell line.
1994
Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways
2000
Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways
2000