Citation Impact
Citing Papers
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist
2004 StandoutNobel
A "Silent" Polymorphism in the MDR 1 Gene Changes Substrate Specificity
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Cutting Edge: Contact-Mediated Suppression by CD4+CD25+ Regulatory Cells Involves a Granzyme B-Dependent, Perforin-Independent Mechanism
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Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: Developmental culling and cancer
2005 StandoutNobel
Interaction of Hydroxylated Collagen IV with the von Hippel-Lindau Tumor Suppressor
2007 StandoutNobel
Treatment of kidney cancer
2009 StandoutNobel
Contrasting Properties of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-Associated Renal Cell Carcinoma
2005 StandoutNobel
The Hypoxia-Inducible Factor 2α N-Terminal and C-Terminal Transactivation Domains Cooperate To Promote Renal Tumorigenesis In Vivo
2007 StandoutNobel
Hypoxia-Inducible Factor Linked to Differential Kidney Cancer Risk Seen with Type 2A and Type 2B VHL Mutations
2007 StandoutNobel
P-glycoprotein: from genomics to mechanism
2003
pVHL Acts as an Adaptor to Promote the Inhibitory Phosphorylation of the NF-κB Agonist Card9 by CK2
2007 StandoutNobel
The Tuberous Sclerosis Complex
2006 Standout
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
2009 StandoutNature
Two critical genes (HLA-DRB1 and ABCF1)in the HLA region are associated with the susceptibility to autoimmune pancreatitis
2006
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
2004 StandoutNobel
Molecular basis of the VHL hereditary cancer syndrome
2002 StandoutNobel
The phosphatidylinositol 3-Kinase–AKT pathway in human cancer
2002 Standout
Characterization of RNASET2, the first human member of the Rh/T2/S family of glycoproteins
2006
Renal-Cell Carcinoma
1996 Standout
Host Genetic Factors and Antiviral Immune Responses to Hepatitis C Virus
2008
APC mutations occur early during colorectal tumorigenesis
1992 StandoutNature
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
1998 StandoutNobel
IgG4-Related Disease
2012 Standout
HLA DRB1*0405-DQB1*0401 haplotype is associated with autoimmune pancreatitis in the Japanese population
2002
Sarcoidosis
2013 Standout
Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease
2001 StandoutNobel
A more efficient method to generate integration-free human iPS cells
2011 StandoutNobel
Activation-Induced Cytidine Deaminase Links Between Inflammation and the Development of Colitis-Associated Colorectal Cancers
2008 StandoutNobel
von Hippel-Lindau disease
2003 Standout
TSC2 regulates VEGF through mTOR-dependent and -independent pathways
2003 StandoutNobel
Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor
2004 StandoutNobel
MDR1 haplotypes significantly minimize intracellular uptake and transcellular P‐gp substrate transport in recombinant LLC‐PK1 cells
2006
Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN
1998 StandoutNobel
Regulation of angiogenesis by hypoxia: role of the HIF system
2003 StandoutNobel
p53 Point mutations in dysplastic and cancerous ulcerative colitis lesions
1993
Failure to prolyl hydroxylate hypoxia‐inducible factor α phenocopies VHL inactivation in vivo
2006 StandoutNobel
Cytogenetic analysis of epithelial renal‐cell tumors: Relationship with a new histopathological classification
1993
Malignant Gliomas in Adults
2008 Standout
The Tumor Suppressor, PTEN/MMAC1, Dephosphorylates the Lipid Second Messenger, Phosphatidylinositol 3,4,5-Trisphosphate
1998 Standout
Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)
1996 Standout
Sarcoidosis HLA class II genotyping distinguishes differences of clinical phenotype across ethnic groups
2010
Analysis of the frequencies of HLA-A, B, and C alleles and haplotypes in the five major ethnic groups of the United States reveals high levels of diversity in these loci and contrasting distribution patterns in these populations
2001
PTEN Deletion and Concomitant c-Myc Activation Do Not Lead to Tumor Formation in Pancreatic β Cells
2008 StandoutNobel
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
2005 StandoutNature
The C. elegans PTEN Homolog, DAF-18, Acts in the Insulin Receptor-like Metabolic Signaling Pathway
1998 StandoutNobel
Loss of a small region around the PTEN locus is a major chromosome 10 alteration in prostate cancer xenografts and cell lines
2003
Microtubules as a target for anticancer drugs
2004 Standout
IgG4-related disease
2014 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
1997 Standout
Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor Is a Death Receptor for Granzyme B during Cytotoxic T Cell–Induced Apoptosis
2000
High-throughput DNA typing of HLA-A, -B, -C, and -DRB1 loci by a PCR–SSOP–Luminex method in the Japanese population
2005
Muscle-Specific Pten Deletion Protects against Insulin Resistance and Diabetes
2005 StandoutNobel
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
1999 Standout
Parkin , a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25–q27
2003
PROLINE HYDROXYLATION AND GENE EXPRESSION
2005 StandoutNobel
SIFT: predicting amino acid changes that affect protein function
2003 Standout
Loss of heterozygosity involving the APC and MCC genetic loci occurs in the majority of human esophageal cancers.
1992
Natural variation in human membrane transporter genes reveals evolutionary and functional constraints
2003
Tumor Suppressor Gene Allelic Loss in Human Renal Cancers
1993
Tuberous sclerosis-associated renal cell carcinoma. Clinical, pathological, and genetic features.
1996
GLUTATHIONE TRANSFERASES
2004 Standout
Epitope Landscape in Breast and Colorectal Cancer
2008 StandoutNobel
A clathrin/dynamin- and mannose-6-phosphate receptor–independent pathway for granzyme B–induced cell death
2003
Essential Role of Pten in Body Size Determination and Pancreatic β-Cell Homeostasis In Vivo
2006 StandoutNobel
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
Effector Memory T Cells, Early Metastasis, and Survival in Colorectal Cancer
2005 Standout
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
2004 Standout
Analysis of genetic alterations in renal cell carcinoma using the polymerase chain reaction
1994
Works of S. Saito being referenced
Long‐term follow‐up of hepatitis C virus infection: HLA class II loci influences the natural history of the disease
2003
Catalog of 46 single-nucleotide polymorphisms (SNPs) in the microsomal glutathione S-transferase 1 (MGST1) gene
2001
Allele frequencies and haplotypic associations defined by allelic DNA typing at HLA class I and class II loci in the Japanese population
2000
Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population
2002
Common regions of deletion on chromosomes 5q, 6q, and 10q in renal cell carcinoma.
1991