Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Anti-Markovnikov alkene oxidation by metal-oxo–mediated enzyme catalysis
2017 StandoutScienceNobel
Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59
2012 StandoutNobel
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin
2012 Standout
EglN2 associates with the NRF 1‐ PGC 1α complex and controls mitochondrial function in breast cancer
2015 StandoutNobel
Unified Synthesis of Polycyclic Alkaloids by Complementary Carbonyl Activation**
2021 StandoutNobel
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
2014 Standout
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
2017 StandoutNobel
ZMYND8 acetylation mediates HIF-dependent breast cancer progression and metastasis
2018
Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer
2014 Nature
Chromatin Reader Brd4 Functions in Ig Class Switching as a Repair Complex Adaptor of Nonhomologous End-Joining
2014 StandoutNobel
Carbonic Anhydrase Related Protein VIII and its Role in Neurodegeneration and Cancer
2010
A Critical Reappraisal of Neutrophil Extracellular Traps and NETosis Mimics Based on Differential Requirements for Protein Citrullination
2016
Privileged Diazepine Compounds and Their Emergence as Bromodomain Inhibitors
2014
High‐level production of amorpha‐4,11‐diene in a two‐phase partitioning bioreactor of metabolically engineered Escherichia coli
2006
Increased Diels-Alderase activity through backbone remodeling guided by Foldit players
2012 StandoutNobel
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Sesquiterpene synthases: Passive catalysts or active players?
2011
Regulatory R-loops as facilitators of gene expression and genome stability
2020
High‐Throughput Screening for Terpene‐Synthase‐Cyclization Activity and Directed Evolution of a Terpene Synthase
2013 StandoutNobel
An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis
2019
Structural Analyses of Covalent Enzyme–Substrate Analog Complexes Reveal Strengths and Limitations of De Novo Enzyme Design
2011 StandoutNobel
Efficacy and Mechanism of Action of Volasertib, a Potent and Selective Inhibitor of Polo-Like Kinases, in Preclinical Models of Acute Myeloid Leukemia
2015
Understanding the tumor immune microenvironment (TIME) for effective therapy
2018 Standout
NF-κB Directs Dynamic Super Enhancer Formation in Inflammation and Atherogenesis
2014
Cholesterol, inflammation and innate immunity
2015
Biosynthesis via carbocations: Theoretical studies on terpene formation
2011
Identification of Druggable Cancer Driver Genes Amplified across TCGA Datasets
2014
mTOR at the nexus of nutrition, growth, ageing and disease
2020 Standout
LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation
2021 StandoutNobel
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Cellular senescence in ageing: from mechanisms to therapeutic opportunities
2020 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Choose and Use Your Chemical Probe Wisely to Explore Cancer Biology
2017
Neutrophil extracellular traps in immunity and disease
2017 Standout
Drug repurposing: progress, challenges and recommendations
2018 Standout
Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition
2013
Optimization of the In-Silico-Designed Kemp Eliminase KE70 by Computational Design and Directed Evolution
2011 StandoutNobel
Intrinsically disordered proteins in cellular signalling and regulation
2014 Standout
Targeted protein degradation: expanding the toolbox
2019
Non-kinase targets of protein kinase inhibitors
2017
BET domain co-regulators in obesity, inflammation and cancer
2012
Modification of Enhancer Chromatin: What, How, and Why?
2013
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Seeding Collaborations to Advance Kinase Science with the GSK Published Kinase Inhibitor Set (PKIS)
2014
Homing in: Mechanisms of Substrate Targeting by Protein Kinases
2018
Structural Prediction of Peptide–MHC Binding Modes
2022
The PI3K Pathway in Human Disease
2017 Standout
Cellular mechanisms and physiological consequences of redox-dependent signalling
2014 Standout
Defining trained immunity and its role in health and disease
2020 Standout
Mitochondria and cancer
2012 Standout
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
CLOCK:BMAL1 is a pioneer-like transcription factor
2014 StandoutNobel
Phospho Switch Triggers Brd4 Chromatin Binding and Activator Recruitment for Gene-Specific Targeting
2013
Furo[3,2‐b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway
2018
Diverse stimuli engage different neutrophil extracellular trap pathways
2017
Organic Photoredox Catalysis
2016 Standout
Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals
2014 Standout
A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes
2014 Science
Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma
2014
Dual Protonophore–Chitinase Inhibitors Dramatically Affect O. volvulus Molting
2014
Physicochemical Properties of Cells and Their Effects on Intrinsically Disordered Proteins (IDPs)
2014
Furo[3,2‐b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway
2018
Identification of Sesquiterpene Synthases fromNostoc punctiformePCC 73102 andNostocsp. Strain PCC 7120
2008
Sesquiterpenoids Lactones: Benefits to Plants and People
2013 Standout
BET Proteins as Targets for Anticancer Treatment
2017
Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism
2010 StandoutNobel
Peptide-binding specificity prediction using fine-tuned protein structure prediction networks
2023 StandoutNobel
The Moderately Efficient Enzyme: Evolutionary and Physicochemical Trends Shaping Enzyme Parameters
2011
Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance
2017 Standout
The Essential Roles of Chemistry in High-Throughput Screening Triage
2014
Oxidants, antioxidants and the current incurability of metastatic cancers
2013
Creation of Customized Bioactivity within a 14-Membered Macrolide Scaffold: Design, Synthesis, and Biological Evaluation Using a Family-18 Chitinase
2015 StandoutNobel
Fluorosulfuryl Isocyanate Enabled SuFEx Ligation of Alcohols and Amines
2021 StandoutNobel
Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
2018 StandoutNobel
Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis
2016 Standout
Plant Aquaporins: Membrane Channels with Multiple Integrated Functions
2008 Standout
Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia
2021 StandoutNobel
Targeting Protein–Protein Interactions in the HIF System
2016
Bromodomain and Extra-Terminal Motif Inhibitors: a Review of Preclinical and Clinical Advances in Cancer Therapy
2019
Chemistry: Chemical con artists foil drug discovery
2014 StandoutNature
Terpene synthases are widely distributed in bacteria
2014 StandoutNobel
New Approach to 1,4‐Benzoxazin‐3‐ones by Electrochemical C−H Amination
2017
Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase
2014 StandoutNobel
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout
Chromatin Contributions to the Regulation of Innate Immunity
2014
Works of S. Picaud being referenced
The C-terminal extension landscape of naturally presented HLA-I ligands
2018
Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery
2011
Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin
2016
A TFEB nuclear export signal integrates amino acid supply and glucose availability
2018
Small-Molecule Inhibition of BRDT for Male Contraception
2012
Amorpha-4,11-diene synthase: Mechanism and stereochemistry of the enzymatic cyclization of farnesyl diphosphate
2005
Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family
2011
Crystal structure of human carbonic anhydrase‐related protein VIII reveals the basis for catalytic silencing
2009
Cloning and expression of two plasma membrane aquaporins expressed during the ripening of grape berry
2003
MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway
2017
Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase
2019
Dual kinase-bromodomain inhibitors for rationally designed polypharmacology
2014
Expression, purification, and characterization of recombinant amorpha-4,11-diene synthase from Artemisia annua L.
2005
Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family
2012
Expression, purification and characterization of recombinant (E)-β-farnesene synthase from Artemisia annua
2005
Cloning, expression, purification and characterization of recombinant (+)-germacrene D synthase from Zingiber officinale
2006
Improved conditions for production of recombinant plant sesquiterpene synthases in Escherichia coli
2006
3,5-Dimethylisoxazoles Act As Acetyl-lysine-mimetic Bromodomain Ligands
2011
A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced‐Fit Pocket Stabilized by a Cation–π Interaction
2014
Structural basis of fumarate hydratase deficiency
2011
PFI-1, a Highly Selective Protein Interaction Inhibitor, Targeting BET Bromodomains
2013
Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains
2014
Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening
2013
Stimulation of Hepatic Apolipoprotein A-I Production by Novel Thieno-Triazolodiazepines: Roles of the Classical Benzodiazepine Receptor, PAF Receptor, and Bromodomain Binding
2013
RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain
2013
A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced‐Fit Pocket Stabilized by a Cation–π Interaction
2014
Citrullination-acetylation interplay guides E2F-1 activity during the inflammatory response
2016
Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit
2012