Standout Papers
- International Union of Pharmacology Nomenclature in Nitric Oxide Research. (1997)
Citation Impact
Citing Papers
TRP channel activation by reversible covalent modification
2006 StandoutNobel
Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney
2006 StandoutNobel
Estrogen Protects Against Cellular Infiltration by Reducing the Expressions of E-Selectin and IL-6 in Endotoxin-Induced Uveitis
1999
Enhanced colonic nitric oxide generation and nitric oxide synthase activity in ulcerative colitis and Crohn's disease.
1995
Reduced oxidative and nitrosative damage in murine experimental colitis in the absence of inducible nitric oxide synthase
1999
Experimental colitis is ameliorated by inhibition of nitric oxide synthase activity.
1995
Greatly increased luminal nitric oxide in ulcerative colitis
1994
Antioxidant Therapy: A New Pharmacological Approach in Shock, Inflammation, and Ischemia/Reperfusion Injury
2001
Aminoguanidine Has Both an Anti-Inflammatory Effect on Experimental Colitis and a Proliferative Effect on Colonic Mucosal Cells
1999
The cryb Mutation Identifies Cryptochrome as a Circadian Photoreceptor in Drosophila
1998 StandoutNobel
Kinetics and Mechanism of Tetrahydrobiopterin-induced Oxidation of Nitric Oxide
1995
Altered immune responses in mice lacking inducible nitric oxide synthase
1995 StandoutNature
Loss of K+ ATP-Channel-Mediated Vasodilation After Induction of Tachyphylaxis to Peroxynitrite
2005
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Generation of peroxynitrite contributes to ischemia-reperfusion injury in isolated rat hearts
1997
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
1995 StandoutNobel
The physiology and pathophysiology of nitric oxide in the brain
2005
Role of inducible nitric oxide synthase expression and peroxynitrite formation in guinea pig ileitis
1995
Long-Term Estrogen Therapy Improves Vascular Function in Male to Female Transsexuals
1997
The inhibitory effect of sodium nitroprusside on HIF-1 activation is not dependent on nitric oxide-soluble guanylyl cyclase pathway
2004 StandoutNobel
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Nitric oxide activates TRP channels by cysteine S-nitrosylation
2006
Effect of 17β‐oestradiol on cytokine‐induced nitric oxide production in rat isolated aorta
1998
Oxidation and Nitrosation of Thiols at Low Micromolar Exposure to Nitric Oxide
2003
Hypertension in mice lacking the gene for endothelial nitric oxide synthase
1995 StandoutNature
Expression and Regulation of Endothelial Nitric Oxide Synthase
1997
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
1999 StandoutNature
Pharmacological modulation of nitric oxide synthesis by mechanism-based inactivators and related inhibitors
1999
Cell signaling by reactive nitrogen and oxygen species in atherosclerosis
2000
Poly(ADP-ribose) synthetase activation mediates increased permeability induced by peroxynitrite in Caco-2BBe cells
1998
Poly(ADP-ribose) polymerase activation by reactive nitrogen species—Relevance for the pathogenesis of inflammation
2005
Peroxynitrite Induces Covalent Dimerization of Epidermal Growth Factor Receptors in A431 Epidermoid Carcinoma Cells
1998
The 1991 Ulf von Euler Lecture:Thel ‐arginine: nitric oxide pathway
1992
The Mitogenic Effect of 17β-Estradiol on in vitro Endothelial Cell Proliferation and on in vivo Reendothelialization Are Both Dependent on Vascular Endothelial Growth Factor
2000
Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia‐reperfusion injury and preconditioning
2003
The Protective Effects of Estrogen on the Cardiovascular System
1999 Standout
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
1999 StandoutNatureNobel
Antifungal Imidazoles Block Assembly of Inducible NO Synthase into an Active Dimer
1999
2006
Nitric oxide synthases: Roles, tolls, and controls
1994 Standout
Pattern Recognition Receptors and Inflammation
2010 Standout
Effect of age on kinetics of nitric oxide release in rat aorta and pulmonary artery.
1996
Peroxynitrite-induced myocardial injury is mediated through matrix metalloproteinase-2
2002
Hydrogen Peroxide Activates Endothelial Nitric-oxide Synthase through Coordinated Phosphorylation and Dephosphorylation via a Phosphoinositide 3-Kinase-dependent Signaling Pathway
2002
Expression of nitric oxide synthases and formation of nitrotyrosine and reactive oxygen species in inflammatory bowel disease
1998
Estrogen Replacement Modulates Resistance Artery Smooth Muscle and Endothelial α2-Adrenoceptor Reactivity
1998
Dietary arginine alters time of symptom onset in Huntington’s disease transgenic mice
2000
Oxidative stress in septic shock and disseminated intravascular coagulation
2002
Widespread tissue distribution, species distribution and changes in activity of Ca2+‐dependent and Ca2+‐independent nitric oxide synthases
1991
Paracrine and autocrine effects of nitric oxide on myocardial function
2000
Cardiac myocytes and fibroblasts contain functional estrogen receptors1
1997
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Direct measurement of nitric oxide in headspace gas produced by a chicken macrophage cell line in a closed culture system
1992
The role of protein nitration in the inhibition of platelet activation by peroxynitrite
2001
Measurement of Nitric Oxide and Peroxynitrite Generation in the Postischemic Heart
1996
Biological aspects of reactive nitrogen species
1999
Nitric oxide synthases: structure, function and inhibition
2001 Standout
Nitric oxide synthases: which, where, how, and why?
1997
The nitration of proteins in platelets: significance in platelet function
2002
Nitric Oxide: Physiological Roles, Biosynthesis and Medical Uses
1999
Peroxynitrite-induced Accumulation of Cyclic GMP in Endothelial Cells and Stimulation of Purified Soluble Guanylyl Cyclase
1995
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
2001 StandoutNature
Regulation of β-Adrenergic Receptor Signaling by S-Nitrosylation of G-Protein-Coupled Receptor Kinase 2
2007 StandoutNobel
DNA Damage Induced by Peroxynitrite: Subsequent Biological Effects
1997
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
Expression of proinflammatory genes during estrogen-induced inflammation of the rat prostate
2000
The discovery of nitric oxide and its role in vascular biology
2006
17-Epiestriol, an Estrogen Metabolite, Is More Potent Than Estradiol in Inhibiting Vascular Cell Adhesion Molecule 1 (VCAM-1) mRNA Expression
2003
Time-dependent actions of nitric oxide synthase inhibition on colonic inflammation induced by trinitrobenzene sulphonic acid in rats
1997
Selective inhibition of constitutive nitric oxide synthase by L-NG-nitroarginine
1993
The effect of 17β-estradiol on MCP-1 serum levels in postmenopausal women
2002
Significant reduction of the antiatherogenic effect of estrogen by long-term inhibition of nitric oxide synthesis in cholesterol-clamped rabbits.
1997
Peroxynitrite-Induced Tyrosine Nitration and Phosphorylation in Human Platelets
1997
The L-Arginine-Nitric Oxide Pathway
1993 Standout
The formation of nitric oxide donors from peroxynitrite
1995
Subunit Interactions of Endothelial Nitric-oxide Synthase
1997
Growth factor activation of the estrogen receptor in vascular cells occurs via a mitogen-activated protein kinase-independent pathway.
1998
L-2-Oxothiazolidine-4-carboxylic acid reverses endothelial dysfunction in patients with coronary artery disease.
1998
Estrogen inhibits the response-to-injury in a mouse carotid artery model.
1995
Evidence for the involvement of peroxynitrite in ischaemic preconditioning in rat isolated hearts
2000
A comparison of the effects of L ‐NAME, 7‐NI and L ‐NIL on carrageenan‐induced hindpaw oedema and NOS activity
1998
Signaling Pathways of Mechanotransduction in Arteriolar Endothelium and Smooth Muscle Cells in Hypertension
2002
Time‐dependent enhancement or inhibition of endotoxin‐induced vascular injury in rat intestine by nitric oxide synthase inhibitors
1994
Inhibition of inducible nitric oxide synthase attenuates platelet adhesion in subpleural arterioles caused by lung ischemia-reperfusion in rabbits
2005
The role of free radicals in cerebral hypoxia and ischemia
2005
Origin and physiological roles of inflammation
2008 StandoutNature
The potential role of peroxynitrite in the vascular contractile and cellular energetic failure in endotoxic shock
1997
Anti-inflammatory drugs and their mechanism of action
1998 Nobel
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
Effect of estrogen on endothelial function and angiogenesis
2002
The Michael Mason Prize Essay 1997. Nitric oxide and bone: what a gas!
1997
Arrhythmogenic Peroxynitrite-Induced Alterations in Mammalian Heart Contractility and Its Prevention with Quercetin-Filled Liposomes
2002
Role of nitric oxide in lipopolysaccharide-induced oxidant stress in the rat kidney
2000
Autoinhibition of Endothelial Nitric-oxide Synthase
1999
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
2004 StandoutNatureNobel
Long-Term Potentiation Is Reduced in Mice That Are Doubly Mutant in Endothelial and Neuronal Nitric Oxide Synthase
1996 StandoutNobel
Nitric oxide and the haemodynamic profile of endotoxin shock in the conscious mouse
1998
Atherosclerosis
2000 StandoutNature
Potential role of nitric oxide in a model of chronic colitis in rhesus macaques
1995
Inflammatory bowel disease: Etiology and pathogenesis
1998 Standout
Differential-display polymerase chain reaction identifies nucleophosmin as an estrogen-regulated gene in human vascular smooth muscle cells
1996
Is nitric oxide overproduction the target of choice for the management of septic shock?
2001
Elevation in arterial blood pressure following the development of tachyphylaxis to peroxynitrite
1996
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
Interactions between endothelial nitric oxide synthase and sex hormones in vascular protection in mice
2002 StandoutNobel
Thiols Protect the Inhibition of Myocardial Aconitase by Peroxynitrite
1998
Glutathione Protects Against Myocardial Ischemia–reperfusion Injury by Detoxifying Peroxynitrite
2000
Estradiol protects mesencephalic dopaminergic neurons from oxidative stress-induced neuronal death
1998
Peroxynitrite inhibits leukocyte-endothelial cell interactions and protects against ischemia-reperfusion injury in rats.
1997
Inhibitors of poly (ADP-ribose) polymerase modulate signal transduction pathways in colitis
2003
Why the Rat-1 Fibroblast Should Replace the SCN as the In Vitro Model of Choice
1998 StandoutNobel
Estrogen inhibits the vascular injury response in estrogen receptor α-deficient mice
1997
Inflammasomes in health and disease
2012 StandoutNature
Does nitric oxide modulate mitochondrial energy generation and apoptosis?
2002
Suppression of Acute Experimental Colitis by a Highly Selective Inducible Nitric-Oxide Synthase Inhibitor,N-[3-(Aminomethyl)benzyl]acetamidine
2001
Nitric Oxide and Peroxynitrite in Postischemic Myocardium
2001
Nitric oxide neurotoxicity in neurodegenerative diseases
2004
Isolation of Putative Progenitor Endothelial Cells for Angiogenesis
1997 StandoutScience
Differential induction of nitric oxide synthase in various organs of the mouse during endotoxaemia: role of TNF-alpha and IL-1-beta.
1994
The Complex Role of Estrogens in Inflammation
2007 Standout
17β-Estradiol reduces vasoconstriction in endothelium-denuded rat aortas through inducible NOS
1998
Heme Oxygenase-1 Is a cGMP-Inducible Endothelial Protein and Mediates the Cytoprotective Action of Nitric Oxide
2000
Ethinylestradiol does not enhance the expression of nitric oxide synthase in bovine endothelial cells but increases the release of bioactive nitric oxide by inhibiting superoxide anion production.
1996
Neuronal Nitric Oxide Synthase Activation and Peroxynitrite Formation in Ischemic Stroke Linked to Neural Damage
1999
Vasomotor hyporeactivity in the anterior cerebral artery during motor activation in Huntington’s disease patients
2000
The Role of Nitric Oxide in Coronary Vascular Effects of Estrogen in Postmenopausal Women
1997
Peroxynitrite induces integrin‐dependent adhesion of human neutrophils to endothelial cells via activation of the Raf‐1/MEK/Erk pathway
2000
Targeting and translocation of endothelial nitric oxide synthase
1999
Prevention of Fatty Streak Formation of 17β-Estradiol Is Not Mediated by the Production of Nitric Oxide in Apolipoprotein E– Deficient Mice
1997
DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite.
1996
No ·NO from NO synthase
1996
Interactions between endothelial nitric oxide synthase and sex hormones in vascular protection in mice
2002 StandoutNobel
Molecular mechanisms and therapeutic strategies related to nitric oxide
1995
Endothelial Dysfunction Coincides With an Enhanced Nitric Oxide Synthase Expression and Superoxide Anion Production
1997
Abnormal Vascular Function and Hypertension in Mice Deficient in Estrogen Receptor β
2002 StandoutScienceNobel
Role of nitric oxide in inflammation and tissue injury during endotoxemia and hemorrhagic shock.
1998
Regulation of Nitric Oxide-Sensitive Guanylyl Cyclase
2003
Peroxynitrite-mediated vasorelaxation: evidence against the formation of circulatingS-nitrosothiols
1998
Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation.
1994 Nobel
Generation and reproductive phenotypes of mice lacking estrogen receptor β
1998 StandoutNobel
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
XIV. International Union of Pharmacology Nomenclature in Nitric Oxide Research
1997 StandoutNobel
Cytokine-Mediated Apoptosis in Cardiac Myocytes
1999
Estradiol-stimulated nitric oxide release in human granulocytes is dependent on intracellular calcium transients: evidence of a cell surface estrogen receptor
2000
Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor
2000 StandoutScienceNobel
1 Arachidonate Metabolism in Blood Cells and the Vessel Wall
1986
Vanilloid (Capsaicin) Receptors and Mechanisms
1999 Standout
Estrogen Modulation of Endothelial Nitric Oxide Synthase
2002
Expression of inducible nitric oxide synthase is increased in patients with heart failure due to ischemic disease
2004
Isoforms of nitric oxide synthase
1995
Extraocular Circadian Phototransduction in Humans
1998 Science
Mechanism of platelet inhibition by nitric oxide: In vivo phosphorylation of thromboxane receptor by cyclic GMP-dependent protein kinase
1998
Blood Flow Regulation by S -Nitrosohemoglobin in the Physiological Oxygen Gradient
1997 Science
The vascular protective effects of estrogen
1996
Chemical nature of nitric oxide storage forms in rat vascular tissue
2002
Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death.
1995 StandoutNobel
Responses of carotid artery in mice deficient in expression of the gene for endothelial NO synthase
1998
Gender Differences in Coronary Artery Diameter Involve Estrogen, Nitric Oxide, and Ca2+-Dependent K+Channels
1996
Endothelial NOS and the Blockade of LTP by NOS Inhibitors in Mice Lacking Neuronal NOS
1994 StandoutScienceNobel
Estradiol Suppresses MCP-1 Expression In Vivo
1998
Formation of free nitric oxide from l-arginine by nitric oxide synthase: direct enhancement of generation by superoxide dismutase.
1994 StandoutNobel
Nitroarginine and tetrahydrobiopterin binding to the haem domain of neuronal nitric oxide synthase using a scintillation proximity assay
1998
Soluble Guanylate Cyclase α 1 and β 1 Gene Transfer Increases NO Responsiveness and Reduces Neointima Formation After Balloon Injury in Rats via Antiproliferative and Antimigratory Effects
2001
Formation of the NO donors glyceryl mononitrate and glyceryl mononitrite from the reaction of peroxynitrite with glycerol
1997
Opposite effects of nitric oxide and nitroxyl on postischemic myocardial injury
1999
Peroxynitrite Reduces Myocardial Infarct Size and Preserves Coronary Endothelium After Ischemia and Reperfusion in Cats
1997
Identification of the domains of neuronal nitric oxide synthase by limited proteolysis
1996
Identification of Authentic Estrogen Receptor in Cultured Endothelial Cells
1996
The Pharmacology of the Ductus Arteriosus
1998
Mercaptoethylguanidine, a Combined Inhibitor of Nitric Oxide Synthase and Peroxynitrite Scavenger, Reduces Trinitrobenzene Sulfonic Acid-Induced Colonic Damage in Rats
1998
Role of calcium and superoxide dismutase in sensitizing mitochondria to peroxynitrite-induced permeability transition
2004
17β-Estradiol Regulation of Human Endothelial Cell Basal Nitric Oxide Release, Independent of Cytosolic Ca 2+ Mobilization
1997
Humoral Phototransduction: Blood Is a Messenger
1996
Vitamin B 2 -based blue-light photoreceptors in the retinohypothalamic tract as the photoactive pigments for setting the circadian clock in mammals
1998 StandoutNobel
Attenuation of vascular relaxation after development of tachyphylaxis to peroxynitrite in vivo
1998
Peroxynitrite induces both vasodilatation and impaired vascular relaxation in the isolated perfused rat heart.
1994
Gender Differences in the Regulation of Blood Pressure
2001
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
2001 StandoutNobel
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
The F2-Isoprostane 8-Epiprostaglandin F2αIncreases Platelet Adhesion and Reduces the Antiadhesive and Antiaggregatory Effects of NO
1998
Medroxyprogesterone Attenuates Estrogen-Mediated Inhibition of Neointima Formation After Balloon Injury of the Rat Carotid Artery
1996
Mechanism of Vascular Smooth Muscle Relaxation by Estrogen in Depolarized Rat and Mouse Aorta
1997
High Glucose Increases Nitric Oxide Synthase Expression and Superoxide Anion Generation in Human Aortic Endothelial Cells
1997
ESTROGENS AND ATHEROSCLEROSIS
1997
Role of Mouse Cryptochrome Blue-Light Photoreceptor in Circadian Photoresponses
1998 StandoutScienceNobel
Peroxynitrite aggravates myocardial reperfusion injury in the isolated perfused rat heart
1997
The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide
1995
Gender Difference in Cytoprotection Induced by Estrogen on Female and Male Bovine Aortic Endothelial Cells
2001
Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-kappa B.
1996 StandoutNobel
Expressional control of the ‘constitutive’ isoforms of nitric oxide synthase (NOS I and NOS III)
1998
Interferon-gamma (IFN-γ)- and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice
1999
Formation of F2-Isoprostanes During Oxidation of Human Low-Density Lipoprotein and Plasma by Peroxynitrite
1995
17β-Estradiol Attenuates Acetylcholine-Induced Coronary Arterial Constriction in Women but Not Men With Coronary Heart Disease
1995
Elevated blood pressures in mice lacking endothelial nitric oxide synthase
1996 StandoutNobel
Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1
2005
Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas.
1994
Estrogen inhibits the vascular injury response in estrogen receptor β-deficient female mice
1999 StandoutNobel
Works of S. Moncada being referenced
Purification to Homogeneity and Characterisation of Rat Brain Recombinant Nitric Oxide Synthase
1995
Nitric oxide synthase activity in ulcerative colitis and Crohn's disease
1993
Endogenous nitric oxide as a modulator of rabbit skeletal muscle microcirculation in vivo
1990
Protective and pathological roles of nitric oxide in endotoxin shock
1992
Vascular smooth muscle contains a depletable store of a vasodilator which is light-activated and restored by donors of nitric oxide.
1993
cGMP mediates the vascular and platelet actions of nitric oxide: confirmation using an inhibitor of the soluble guanylyl cyclase.
1996
Paradoxical fate and biological action of peroxynitrite on human platelets.
1994
Eicosanoids in inflammation.
1984 Nobel
International Union of Pharmacology Nomenclature in Nitric Oxide Research.
1997 StandoutNobel
Induction of calcium-dependent nitric oxide synthases by sex hormones.
1994