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Citing Papers
Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection
2005 StandoutNobel
Control ofLeishmania majorInfection in Mice Lacking TNF Receptors
1998
Functional diversity of helper T lymphocytes
1996 StandoutNature
Altered immune responses in mice lacking inducible nitric oxide synthase
1995 StandoutNature
Evidence for antiviral effect of nitric oxide. Inhibition of herpes simplex virus type 1 replication.
1993
Impaired immune and acute-phase responses in interleukin-6-deficient mice
1994 StandoutNatureNobel
Oxidative damage to DNA: Formation, measurement, and biological significance
1997
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
1998 StandoutNature
ICOS co-stimulatory receptor is essential for T-cell activation and function
2001 StandoutNatureNobel
The Importance of Th2 Cytokines in Protective Immunity to Nematodes
1992
TNF‐α mediates the induction of nitric oxide synthase in macrophages but not in neutrophils in experimental cutaneous leishmaniasis
2003
Hypertension in mice lacking the gene for endothelial nitric oxide synthase
1995 StandoutNature
Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure
1992 Standout
Tumor necrosis factor-α is required in the protective immune response against mycobacterium tuberculosis in mice
1995 Standout
The role of nitrogen oxides as effector molecules of parasite killing
1990
Resistance to Leishmania major infection correlates with the induction of nitric oxide synthase in murine macrophages
1991
Exogenous and Endogenous Type I Interferons Inhibit Interferon-γ-Induced Nitric Oxide Production and Nitric Oxide Synthase Expression in Murine Peritoneal Macrophages
1995
T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions
1998 StandoutNature
Effective clearance of intracellular Leishmania majorin vivo requires Pten in macrophages
2008 StandoutNobel
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
2007 StandoutNature
A role for gamma interferon-induced nitric oxide in pulmonary clearance of Cryptococcus neoformans.
1995
Nitric oxide: Cytokine-regulation of nitric oxide in host resistance to intracellular pathogens
1994
The Molecular Cell Biology of Interferon-gamma and its Receptor
1993
Cross-regulatory roles of interleukin (IL)-12 and IL-10 in atherosclerosis.
1996
Lymphocyte responses and cytokines
1994 Standout
Pre‐exposure of murine macrophages to lipopolysaccharide inhibits the induction of nitric oxide synthase and reduces leishmanicidal activity
1993
The Regulation of Immunity to Leishmania Major
1995 Standout
IFN-γ-induced TNF-α is a prerequisite forin vitro production of nitric oxide generated in murine peritoneal macrophages by IFN-γ
1998
Inhibition of NADPH supply by 6‐aminonicotinamide: effect on glutathione, nitric oxide and superoxide in J774 cells
1998
Role of T‐Cell Derived Cytokines in the Downregulation of Immune Responses in Parasitic and Retroviral Infection
1992
l-N6-(1-Iminoethyl)-lysine potently inhibits inducible nitric oxide synthase and is superior to NG-monomethyl-arginine in vitro and in vivo
1995
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
1998 StandoutNature
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Regulation of the immune response by nitric oxide differentially produced by T helper type 1 and T helper type 2 cells
1994
Cell-mediated cytotoxicity
1993 StandoutNobel
Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major
2007 Standout
Mammalian Nitric Oxide Synthases
1992
Disruption of CD40–CD40 Ligand Interactions Results in an Enhanced Susceptibility to Leishmania amazonensis Infection
1996
Transgenic mice expressing high levels of soluble TNF‐R1 fusion protein are protected from lethal septic shock and cerebral malaria, and are highly sensitive to Listeria monocytogenes and Leishmania major infections
1995
Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease
2002 StandoutNature
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
Transforming growth factor β2 inhibits interleukin 1β- and tumour necrosis factor α-induction of nitric oxide synthase in rat renal mesangial cells
1991
Inflammation, Atherosclerosis, and Coronary Artery Disease
2005 Standout
Role of nitric oxide synthesis in macrophage antimicrobial activity
1991 Standout
Nitric oxide, a biological effector
1991
Exacerbation of experimental murine cutaneous leishmaniasis with CD4+Leishmania major‐specific T cell lines or clones which secrete interferon‐γ and mediate parasite‐specific delayed‐type hypersensitivity
1991 StandoutNobel
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
1996 StandoutNatureNobel
Regulation of Immunity to Parasites by T Cells and T Cell-Derived Cytokines
1992 Standout
Nonspecific defence mechanism: the role of nitric oxide
1991
Interleukin-13 Effectively Down-regulates the Monocyte Inflammatory Potential During Traumatic Stress
1995
Protection against Leishmania major infection in genetically susceptible BALB/c mice by gp63 delivered orally in attenuated Salmonella typhimurium (AroA- AroD-).
1995
Leishmania species: models of intracellular parasitism
1999
Differential induction of nitric oxide synthase in various organs of the mouse during endotoxaemia: role of TNF-alpha and IL-1-beta.
1994
Biochemistry of Nitric Oxide and Its Redox-Activated Forms
1992 StandoutScience
Generation of EPR-detectable nitrosyl-iron complexes in tumor target cells cocultured with activated macrophages
1991
An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection.
1993 Standout
The Immunological Synapse: A Molecular Machine Controlling T Cell Activation
1999 StandoutScience
Immunology of Tuberculosis
2001 Standout
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates
2011 StandoutNobel
The Central Role of CD4+ T Cells in the Antitumor Immune Response
1998
Recombinant interleukin 12 cures mice infected with Leishmania major.
1993 Standout
Mechanism of suppression of nitric oxide synthase expression by interleukin-4 in primary mouse macrophages
1994
Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes
2002 StandoutScience
Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice.
1993
Cytokine-mediated regulation of chronic intestinal helminth infection.
1994
Cloning, characterization, and expression of a cDNA encoding an inducible nitric oxide synthase from the human chondrocyte.
1993
Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells.
1990
Rapidly Fatal Leishmaniasis in Resistant C57BL/6 Mice Lacking TNF
2001
Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages.
1992 Standout
Cutting Edge: Inducible Costimulator Protein Regulates Both Th1 and Th2 Responses to Cutaneous Leishmaniasis
2002
Killing of Plasmodium falciparum in vitro by nitric oxide derivatives
1991
Low Dose TGF-β Attenuates IL-12 Responsiveness in Murine Th Cells
1998
Cloning and Characterization of Inducible Nitric Oxide Synthase from Mouse Macrophages
1992 StandoutScience
Lack of a role for transforming growth factor-β in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation
2001 StandoutNobel
Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide.
1993
Macrophage-stimulating protein inhibits induction of nitric oxide production by endotoxin- or cytokine-stimulated mouse macrophages.
1994
Infection of C57BL/10ScCr and C57BL/10ScNCr mice withLeishmania majorreveals a role for Toll-like receptor 4 in the control of parasite replication
2004
Nitric oxide derived from L-arginine impairs cytoplasmic pH regulation by vacuolar-type H+ ATPases in peritoneal macrophages.
1991
T cell genetic background determines default T helper phenotype development in vitro.
1995
Development of T H 1 CD4 + T Cells Through IL-12 Produced by Listeria -Induced Macrophages
1993 StandoutScience
Low dose TGF-beta attenuates IL-12 responsiveness in murine Th cells.
1998
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
2003 StandoutNobel
Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils
1997 StandoutNobel
NITRIC OXIDE AND MACROPHAGE FUNCTION
1997 Standout
Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide.
1993
Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis
1995
Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line.
1992
Antileishmanial defense in macrophages triggered by tumor necrosis factor expressed on CD4+ T lymphocyte plasma membrane.
1991
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
Toll-Like Receptor 4 Contributes to Efficient Control of Infection with the Protozoan ParasiteLeishmania major
2004
CELLULAR RESPONSES TO INTERFERON-γ
1997 Standout
Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death.
1995 StandoutNobel
Resistance to nitric oxide in Mycobacterium avium complex and its implication in pathogenesis
1993
Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide.
1993 Standout
Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major.
1994
Carbon Monoxide: a Putative Neural Messenger
1993 StandoutScience
Role of nitric oxide in parasitic infections
1995
Tumor necrosis factor alpha (TNF-alpha) and TNF-beta and their receptors in experimental cutaneous leishmaniasis
1994
Isolation of a nitric oxide inhibitor from mammary tumor cells and its characterization as phosphatidyl serine.
1994
Inhibitory effect of nitric oxide on the replication of a murine retrovirus in vitro and in vivo
1995
CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit
2008 StandoutNobel
Cytokine-Induced Synthesis of Nitrogen Oxides in Macrophages: A Protective Host Response to Leishmania and Other Intracellular Pathogens
1991
T-cell quality in memory and protection: implications for vaccine design
2008
Modulation of Baroreceptor Activity by Nitric Oxide andS-Nitrosocysteine
1995
Nitric oxide produced during murine listeriosis is protective
1994
Multiple Defects of Immune Cell Function in Mice with Disrupted Interferon-γ Genes
1993 StandoutScience
Nitric oxide is an important mediator for tumoricidal activity in vivo.
1994
Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase.
1996
Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-kappa B.
1996 StandoutNobel
Mechanisms involved in mycobacterial growth inhibition by gamma interferon-activated bone marrow macrophages: role of reactive nitrogen intermediates
1991
The Role of T H 1 and T H 2 Cells in a Rodent Malaria Infection
1993 Science
Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro
1994
Elevated blood pressures in mice lacking endothelial nitric oxide synthase
1996 StandoutNobel
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
Impairment of Alternative Macrophage Activation Delays Cutaneous Leishmaniasis in Nonhealing BALB/c Mice
2006
Reciprocal Control of T Helper Cell and Dendritic Cell Differentiation
1999 StandoutScience
Works of S Millott being referenced
A possible novel pathway of regulation by murine T helper type‐2 (Th2) cells of a Th1 cell activity via the modulation of the induction of nitric oxide synthase on macrophages
1991
Macrophage activation by interferon‐γ from host‐protective T cells is inhibited by interleukin (IL) 3 and IL 4 produced by disease‐promoting T cells in leishmaniasis
1989
Tumor necrosis factor-alpha synergizes with IFN-gamma in mediating killing of Leishmania major through the induction of nitric oxide.
1990
Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine.
1990
Tumour necrosis factor (TNF-alpha) in leishmaniasis. II. TNF-alpha-induced macrophage leishmanicidal activity is mediated by nitric oxide from L-arginine.
1990
A repetitive peptide of Leishmania can activate T helper type 2 cells and enhance disease progression.
1990
Tumour necrosis factor (TNF alpha) in leishmaniasis. I. TNF alpha mediates host protection against cutaneous leishmaniasis.
1990