Citation Impact
Citing Papers
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
2005 Standout
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry
1997
RAP46 Is a Negative Regulator of Glucocorticoid Receptor Action and Hormone-induced Apoptosis
1998
Oncogenic kinase signalling
2001 StandoutNature
A novel protein modification pathway related to the ubiquitin system
1998
Bcl-2 Targets the Protein Kinase Raf-1 to Mitochondria
1996
harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-XL
1997 Standout
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
1998 StandoutNatureNobel
Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis
1998 Standout
The activity of the murine Bax promoter is regulated by Sp1/3 and E-box binding proteins but not by p53
1999
Bcl-2 Family Proteins: Strategies for Overcoming Chemoresistance in Cancer
1997
Bcl-2 family proteins
1998
The biochemistry of apoptosis
2000 StandoutNature
A protein conjugation system essential for autophagy
1998 StandoutNatureNobel
A family of ubiquitin‐like proteins binds the ATPase domain of Hsp70‐like Stch
2000
Apoptosis and Its Role in Human Disease
1994
Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN
1998 StandoutNobel
The C. elegans Protein EGL-1 Is Required for Programmed Cell Death and Interacts with the Bcl-2–like Protein CED-9
1998 StandoutNobel
Cellular processing of platinum anticancer drugs
2005 Standout
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling
2001
Immunity, Inflammation, and Cancer
2010 Standout
Plasma cell differentiation requires the transcription factor XBP-1
2001 Nature
The pathobiology of mucositis
2004 Standout
Inhibition of p53 Transcriptional Activity by Bcl-2 Requires Its Membrane-anchoring Domain
1999
bcl-2 protects against Fas-based but not perforin-based T cell-mediated cytolysis
1996
Molecular genetics of prostate cancer
2000
Apaf1 Is Required for Mitochondrial Pathways of Apoptosis and Brain Development
1998
Two CD95 (APO-1/Fas) signaling pathways
1998 Standout
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
1995 StandoutNature
The Fas Death Factor
1995 StandoutScience
Neural apoptosis
1995
Molecular characterization of mitochondrial apoptosis-inducing factor
1999 StandoutNature
Mechanism of folding chamber closure in a group II chaperonin
2010 StandoutNatureNobel
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
1998 StandoutNature
Caspase inhibitors block the retinal ganglion cell death following optic nerve transection
1999
BI-1 Regulates an Apoptosis Pathway Linked to Endoplasmic Reticulum Stress
2004 StandoutNobel
Proapoptotic Protein Bax Heterodimerizes with Bcl-2 and Homodimerizes with Bax via a Novel Domain (BH3) Distinct from BH1 and BH2
1996
The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy
1997
Processing of β-Amyloid Precursor-like Protein-1 and -2 by γ-Secretase Regulates Transcription
2002
Regulating protein degradation by ubiquitination
1997
The TRA-1A Sex Determination Protein of C. elegans Regulates Sexually Dimorphic Cell Deaths by Repressing the egl-1 Cell Death Activator Gene
1999 StandoutNobel
Lyn and Fgr Protein-tyrosine Kinases Prevent Apoptosis during Retinoic Acid-induced Granulocytic Differentiation of HL-60 Cells
1996 StandoutNobel
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways
2004
The Ubiquitin-related BAG-1 Provides a Link between the Molecular Chaperones Hsc70/Hsp70 and the Proteasome
2000
Toso, a Cell Surface, Specific Regulator of Fas-Induced Apoptosis in T Cells
1998
Mechanisms of resistance to cisplatin
2001
Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ
1996 StandoutNobel
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death
2001 StandoutScience
Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice
2002 StandoutNobel
Dysregulation of Apoptosis in Cancer
1999
Life, death, and the pursuit of apoptosis.
1996
Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
2003 Standout
The Bcl-2 Protein Family: Arbiters of Cell Survival
1998 StandoutScience
Inhibition of CPP32-Like Proteases Rescues Axotomized Retinal Ganglion Cells from Secondary Cell DeathIn Vivo
1998
Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked
1997 StandoutScience
Cancer Cell Cycles
1996 StandoutScience
FAP-1: A Protein Tyrosine Phosphatase That Associates with Fas
1995 Science
Sensing cooperativity in ATP hydrolysis for single multisubunit enzymes in solution
2011 StandoutNobel
Death Receptors: Signaling and Modulation
1998 StandoutScience
Bcl-2-mediated alterations in endoplasmic reticulum Ca 2+ analyzed with an improved genetically encoded fluorescent sensor
2004 StandoutNobel
The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
2011 StandoutScience
Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct.
1996 StandoutNobel
Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1.
1996
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage
2004 StandoutNobel
Microsatellite instability, apoptosis, and loss of p53 function in drug-resistant tumor cells.
1996
Integrin Signaling
1999 StandoutScience
cis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects
2008 StandoutNobel
Molecular thanatopsis: a discourse on the BCL2 family and cell death
1996
The Yin and Yang of T Cell Costimulation
1995 StandoutScienceNobel
Protection of CLL B cells by a follicular dendritic cell line is dependent on induction of Mcl-1
2002
IEX -1L, an Apoptosis Inhibitor Involved in NF-κB-Mediated Cell Survival
1998 Science
The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis
1997 StandoutScience
Surfing the p53 network
2000 StandoutNature
Ultrafast Dynamics of Flavins in Five Redox States
2008 StandoutNobel
Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays
1998 Standout
The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein.
1996
Mitochondria and Apoptosis
1998 StandoutScience
A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation
2001 StandoutNobel
Folding of Newly Translated Proteins In Vivo: The Role of Molecular Chaperones
2001
Apoptotic Death of β Cells after Optic Nerve Transection in Adult Cats
2003 StandoutNobel
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
BAG1 Over‐expression in Brain Protects Against Stroke
2003
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
Induction of apoptosis by mifepristone and tamoxifen in human LNCaP prostate cancer cells in culture
2000
Structure of trigger factor binding domain in biologically homologous complex with eubacterial ribosome reveals its chaperone action
2005 StandoutNobel
Bax alpha perturbs T cell development and affects cell cycle entry of T cells.
1996
Apoptosis by a cytosolic extract from Fas-activated cells.
1995
Disruption of epithelial cell-matrix interactions induces apoptosis
1994 Standout
Works of S Krajewski being referenced
Reversal of EBV Immortalization Precedes Apoptosis in IL-6–Induced Human B Cell Terminal Differentiation
1997
Up‐regulation of Bax Protein in Degenerating Retinal Ganglion Cells Precedes Apoptotic Cell Death after Optic Nerve Lesion in the Rat
1997
Bag1 is a regulator and marker of neuronal differentiation
2002
Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity
1995
Regulation of Bcl-2 oncoprotein levels with differentiation of human neuroblastoma cells.
1993
The control of apoptosis and drug resistance in ovarian cancer: influence of p53 and Bcl-2.
1995
Gamma-radiation induces upregulation of Bax protein and apoptosis in radiosensitive cells in vivo.
1996
Intracellular metabolism of Ara-C and resulting DNA fragmentation and apoptosis of human AML HL-60 cells possessing disparate levels of Bcl-2 protein.
1996
Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers.
1996
Caspases 3 and 9 Send a Pro-Apoptotic Signal from Synapse to Cell Body in Olfactory Receptor Neurons
2001
Analysis of Bax and Bcl-2 expression in p53-immunopositive breast cancers.
1997