Citation Impact
Citing Papers
Metformin decreases hepatocellular carcinoma risk in a dose-dependent manner: population-based and in vitro studies
2012
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
2002 Standout
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
Transcriptional regulation of the interleukin 2 gene by glucocorticoid hormones. Role of steroid receptor and antigen-responsive 5'-flanking sequences.
1990
A Family of Drug Transporters: the Multidrug Resistance-Associated Proteins
2000
Multidrug resistance in cancer: role of ATP–dependent transporters
2002 Standout
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis
1996 Standout
EGFR Antagonists in Cancer Treatment
2008 Standout
Role of yeast in cancer research
1992 StandoutNobel
The Intracisternal A-Particle Gene Family: Structure and Functional Aspects
1988
A High-Resolution STS, EST, and Gene-Based Physical Map of the Hereditary Paraganglioma Region on Chromosome 11q23
1997
Retinoic acid receptors: From molecular mechanisms to cancer therapy
2014
Use of arsenic trioxide (As2O3) in the treatment of patients with acute promyelocytic leukemia
2003 Standout
Hepatocellular carcinoma
2018 Standout
Arsenic inhibition of telomerase transcription leads to genetic instability
2001
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases
1997 Standout
Chromatin structural elements and chromosomal translocations in leukemia
2006
Hallmarks of aging: An expanding universe
2023 Standout
A genetic model for colorectal tumorigenesis
1990 Standout
Angiogenesis and antiangiogenic therapy in hematologic malignancies
2006
High-Resolution Profiling of Histone Methylations in the Human Genome
2007 Standout
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
1996 StandoutNature
Malignancies, Prothrombotic Mutations, and the Risk of Venous Thrombosis
2005 Standout
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
2006 StandoutNobel
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Identification of genes involved in growth autonomy of hematopoietic cells by analysis of factor-independent mutants
1988
Role of the histone deacetylase complex in acute promyelocytic leukaemia
1998 Nature
Hypoxia-HIF-1α-C/EBPα/Runx1 signaling in leukemic cell differentiation
2009
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Cobalt chloride and low oxygen tension trigger differentiation of acute myeloid leukemic cells: possible mediation of hypoxia-inducible factor-1α
2003
Molecular themes in oncogenesis
1991 StandoutNobel
Control of Male Sexual Behavior and Sexual Orientation in Drosophila by the fruitless Gene
1996 StandoutNobel
Benefits of Metformin in Attenuating the Hallmarks of Aging
2020
Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer
1998 StandoutNature
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
2000 StandoutNature
Metal-induced oxidative stress and signal transduction
2004
Update on Tumor Cell Procoagulant Factors
2001
Tumor Angiogenesis
2008 Standout
Hepatocellular carcinoma
2022 Standout
The paradox of arsenic: molecular mechanisms of cell transformation and chemotherapeutic effects
2002
Sustained expression of the human protooncogene MYCN rescues rat embryo cells from senescence.
1988 StandoutNobel
Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
2003 Standout
Checkpoints: Controls That Ensure the Order of Cell Cycle Events
1989 StandoutScienceNobel
Cloning and characterization of CLLD6, CLLD7, and CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphocytic leukemia.
2001
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Transcription Factors, Normal Myeloid Development, and Leukemia
1997
Human Retinoblastoma Susceptibility Gene: Cloning, Identification, and Sequence
1987 StandoutScience
Cell Apoptosis Induced by Carcinogenic Metals
2001
Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9
2002 StandoutNobel
Identification of a new common provirus integration site in gross passage A murine leukemia virus-induced mouse thymoma DNA.
1987
Establishment of an interleukin-5-dependent subclone from an interleukin-3-dependent murine hemopoietic progenitor cell line, LyD9, and its malignant transformation by autocrine secretion of interleukin-5.
1990 StandoutNobel
Binding of a Cellular Protein to the Gibbon Ape Leukemia Virus Enhancer
1987
Insertion of an intracisternal A particle within the 5'-regulatory region of a gene encoding folate-binding protein in L1210 leukemia cells in response to low folate selection. Association with increased protein expression.
1992 StandoutNobel
G Protein Signaling and Vein Graft Intimal Hyperplasia
1998 StandoutNobel
The BTB/POZ domain: a new protein-protein interaction motif common to DNA- and actin-binding proteins.
1995
Regulatory elements that modulate expression of human c-myc.
1987 StandoutNobel
The Chemistry and Biochemistry of Vanadium and the Biological Activities Exerted by Vanadium Compounds
2004 Standout
How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions*
2000 Standout
The Ecology of Arsenic
2003 StandoutScience
A larger number of L chains (Tac) enhance the association rate of interleukin 2 to the high affinity site of the interleukin 2 receptor.
1988 StandoutNobel
Aortocoronary Saphenous Vein Graft Disease
1998 Standout
Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family
1991 StandoutNobel
Induction of tumor arrest and differentiation with prolonged survival by intermittent hypoxia in a mouse model of acute myeloid leukemia
2005
Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo
2001
Growth Factors and Cancer
1991 StandoutScience
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Biochemical evidence for a third chain of the interleukin-2 receptor.
1991 StandoutNobel
MLL leukemia induction by genome editing of human CD34+ hematopoietic cells
2015
Arsenic inhibition of telomerase transcription leads to genetic instability
2001
Molecular pathogenesis of the chromosome 16 inversion in the M4Eo subtype of acute myeloid leukemia [see comments]
1995
mTOR: a pharmacologic target for autophagy regulation
2015 Standout
Oncogene v-src transforms and establishes embryonic rodent fibroblasts but not diploid human fibroblasts.
1988 StandoutNobel
Inhibition of endothelial cell activation by adenovirus-mediated expression of I kappa B alpha, an inhibitor of the transcription factor NF-kappa B.
1996
Role of NADPH oxidase in arsenic-induced reactive oxygen species formation and cytotoxicity in myeloid leukemia cells
2004
Mutations in SDHD , a Mitochondrial Complex II Gene, in Hereditary Paraganglioma
2000 StandoutScience
Fusion proteins of the retinoic acid receptor-α recruit histone deacetylase in promyelocytic leukaemia
1998 Nature
Cell apoptosis induced by carcinogenic metals
2001
Transcription Factors, Normal Myeloid Development, and Leukemia
1997
DPC4 , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1
1996 StandoutScience
Demonstration of a non-Tac peptide that binds interleukin 2: a potential participant in a multichain interleukin 2 receptor complex.
1986
Interleukin-2: Inception, Impact, and Implications
1988 StandoutScience
Works of S J Chen being referenced
Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy
2012
The Mll-Een knockin fusion gene enhances proliferation of myeloid progenitors derived from mouse embryonic stem cells and causes myeloid leukaemia in chimeric mice
2006
Tissue factors on acute promyelocytic leukemia and endothelial cells are differently regulated by retinoic acid, arsenic trioxide and chemotherapeutic agents
1999
Treatment of acute promyelocytic leukemia with arsenic compounds: In vitro and in vivo studies
2001
Apoptosis and Growth Inhibition in Malignant Lymphocytes After Treatment With Arsenic Trioxide at Clinically Achievable Concentrations
1999
Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia
2000
Molecular cytogenetic characterization and clinical relevance of additional, complex and/or variant chromosome abnormalities in acute promyelocytic leukemia
2001
Enhanced growth suppression of Philadephia1 leukemia cells by targeting bcr3/abl2 and VEGF through antisense strategy
2005
PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors.
1994
Adenovirus-mediated gene transfer of soluble vascular cell adhesion molecule to porcine interposition vein grafts.
1994
A viral long terminal repeat in the interleukin 2 gene of a cell line that constitutively produces interleukin 2.
1985
Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia.
1993