Citation Impact
Citing Papers
Free Fatty Acid Impairment of Nitric Oxide Production in Endothelial Cells Is Mediated by IKKβ
2005
The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans
2012 StandoutNobel
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
2009 StandoutScience
Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids
2005
FoxOs Enforce a Progression Checkpoint to Constrain mTORC1-Activated Renal Tumorigenesis
2010 StandoutNobel
Theaflavins attenuate hepatic lipid accumulation through activating AMPK in human HepG2 cells
2007
Hypoinsulinaemia, glucose intolerance and diminished β-cell size in S6K1-deficient mice
2000 Nature
Use and Abuse of HOMA Modeling
2004 Standout
siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle
2006
β-Arrestin Is Crucial for Ubiquitination and Down-regulation of the Insulin-like Growth Factor-1 Receptor by Acting as Adaptor for the MDM2 E3 Ligase
2005 StandoutNobel
mTOR Signaling in Growth Control and Disease
2012 Standout
Inflammation and metabolic disorders
2006 StandoutNature
Biology of insulin‐like growth factors in development
2003
Defective insulin secretion in pancreatic β cells lacking type 1 IGF receptor
2002
Central nervous system control of food intake and body weight
2006 StandoutNature
mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery
2002 Standout
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Islet β cell expression of constitutively active Akt1/PKBα induces striking hypertrophy, hyperplasia, and hyperinsulinemia
2001
Defining high-fat-diet rat models: metabolic and molecular effects of different fat types
2006
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
2008 Standout
TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation
2009 Standout
The phosphatidylinositol 3-Kinase–AKT pathway in human cancer
2002 Standout
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
2003 Standout
Hepatocyte growth factor exerts a proliferative effect on oval cells through the PI3K/AKT signaling pathway
2003
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
2010 Standout
Reduced Expression of the Insulin Receptor in Mouse Insulinoma (MIN6) Cells Reveals Multiple Roles of Insulin Signaling in Gene Expression, Proliferation, Insulin Content, and Secretion
2004
Relationship of the Trp64Arg polymorphism of the beta3-adrenoceptor gene to central adiposity and high blood pressure: interaction with age. Cross-sectional and longitudinal findings of the Olivetti Prospective Heart Study
2001
Leptin action in the forebrain regulates the hindbrain response to satiety signals
2005
Mechanisms of mitogenic and anti-apoptotic signaling by glucose-dependent insulinotropic polypeptide in beta(INS-1)-cells
2002
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
2002 StandoutNature
Inflammation, stress, and diabetes
2005 Standout
Inflammation and insulin resistance
2006 Standout
Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K
2002
Molecular insights into insulin action and secretion
2002
Insulin and insulin-like growth factor signalling in neoplasia
2008 Standout
Upstream and downstream of mTOR
2004 Standout
Enhanced Leptin-Stimulated Pi3k Activation in the CNS Promotes White Adipose Tissue Transdifferentiation
2007 StandoutNobel
Biology of Incretins: GLP-1 and GIP
2007 Standout
Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
2009 Standout
Candidate Genes for Type 2 Diabetes
2004
The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
2006 Standout
β-Arrestin1 Mediates Insulin-like Growth Factor 1 (IGF-1) Activation of Phosphatidylinositol 3-Kinase (PI3K) and Anti-apoptosis
2003 StandoutNobel
Mechanisms linking obesity to insulin resistance and type 2 diabetes
2006 StandoutNature
Altered function of insulin receptor substrate-1–deficient mouse islets and cultured β-cell lines
1999
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
Hedgehog signaling in animal development: paradigms and principles
2001 Standout
Glucagon-Like Peptide 1 Inhibits Cell Apoptosis and Improves Glucose Responsiveness of Freshly Isolated Human Islets
2003
Wnt signaling: relevance to β-cell biology and diabetes
2008
Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice
2002
The Physiology of Glucagon-like Peptide 1
2007 Standout
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1
2006
Irs-2 coordinates Igf-1 receptor-mediated β-cell development and peripheral insulin signalling
1999
β-Arrestin and Mdm2 Mediate IGF-1 Receptor-stimulated ERK Activation and Cell Cycle Progression
2007 StandoutNobel
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells
1999
Increased ocular levels of IGF-1 in transgenic mice lead to diabetes-like eye disease
2004
The Hyperglycemia-induced Inflammatory Response in Adipocytes
2004
Molecular mechanisms of mTOR-mediated translational control
2009 Standout
Replication of hepatitis C virus
2007 StandoutNobel
Glucagon-Like Peptide 1 Induces Pancreatic β-Cell Proliferation Via Transactivation of the Epidermal Growth Factor Receptor
2003
Protein Kinase Cζ Activation Mediates Glucagon-Like Peptide-1–Induced Pancreatic β-Cell Proliferation
2001
Disruption of Tsc2 in pancreatic β cells induces β cell mass expansion and improved glucose tolerance in a TORC1-dependent manner
2008
mTOR Is Essential for Growth and Proliferation in Early Mouse Embryos and Embryonic Stem Cells
2004 StandoutNobel
Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction
2006 Standout
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Type 2 diabetes: principles of pathogenesis and therapy
2005 Standout
Defective insulin secretion in pancreatic β cells lacking type 1 IGF receptor
2002
Pancreas development is promoted by cyclopamine, a Hedgehog signaling inhibitor
1998
Intracellular ceramide synthesis and protein kinase Cζ activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells
2004
Immunological and Inflammatory Functions of the Interleukin-1 Family
2009 Standout
Glucose-Dependent Insulinotropic Polypeptide Promotes β-(INS-1) Cell Survival via Cyclic Adenosine Monophosphate-Mediated Caspase-3 Inhibition and Regulation of p38 Mitogen-Activated Protein Kinase
2003
Immunocytochemical Detection of Phosphatidylinositol 3-kinase Activation by Insulin and Leptin
2003
Leptin action in the forebrain regulates the hindbrain response to satiety signals
2005
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Studying Hepatitis C Virus: Making the Best of a Bad Virus
2007 StandoutNobel
Domain-specific Mutations of a Transforming Growth Factor (TGF)-β1 Latency-associated Peptide Cause Camurati-Engelmann Disease Because of the Formation of a Constitutively Active Form of TGF-β1
2001
Domains of the Insulin-Like Growth Factor I Receptor Required for the Activation of Extracellular Signal-Regulated Kinases*
2000
Islet β cell expression of constitutively active Akt1/PKBα induces striking hypertrophy, hyperplasia, and hyperinsulinemia
2001
Mitochondrial Dysfunction and Type 2 Diabetes
2005 StandoutScience
Defects of the insulin receptor substrate (IRS) system in human metabolic disorders
2001
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
Glucose- and Interleukin-1β-Induced β-Cell Apoptosis Requires Ca2+ Influx and Extracellular Signal-Regulated Kinase (ERK) 1/2 Activation and Is Prevented by a Sulfonylurea Receptor 1/Inwardly Rectifying K+ Channel 6.2 (SUR/Kir6.2) Selective Potassium Channel Opener in Human Islets
2004
Critical nodes in signalling pathways: insights into insulin action
2006 Standout
Glucose-Dependent Insulinotropic Polypeptide Is a Growth Factor for β (INS-1) Cells by Pleiotropic Signaling
2001
Mechanisms of Diabetic Complications
2013 Standout
mTOR Inhibition by Rapamycin Prevents β-Cell Adaptation to Hyperglycemia and Exacerbates the Metabolic State in Type 2 Diabetes
2008
Essential Role of Pten in Body Size Determination and Pancreatic β-Cell Homeostasis In Vivo
2006 StandoutNobel
Pancreatic β-cell growth and survival in the onset of type 2 diabetes: a role for protein kinase B in the Akt?
2004
FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction
2002
Deletion of Pten in Pancreatic β-Cells Protects Against Deficient β-Cell Mass and Function in Mouse Models of Type 2 Diabetes
2010 StandoutNobel
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
Works of S Hügl being referenced
Synergistic effects of troglitazone and oleate on the translatability of preproinsulin mRNA from INS-1 cells
2002
Insulin-like Growth Factor I (IGF-I)-stimulated Pancreatic β-Cell Growth Is Glucose-dependent
1998
Differential Activation of Protein Kinase B and p70S6K by Glucose and Insulin-like Growth Factor 1 in Pancreatic β-Cells (INS-1)
2001
Hepatocyte growth factor stimulates proliferation of pancreatic beta-cells particularly in the presence of subphysiological glucose concentrations
2002
Free Fatty Acid-Induced Inhibition of Glucose and Insulin-Like Growth Factor I-Induced Deoxyribonucleic Acid Synthesis in the Pancreatic β-Cell Line INS-11
2001
Stimulation of pancreatic β-cell proliferation by growth hormone is glucose-dependent: signal transduction via Janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling
1999
Activation of IRS-2—Mediated Signal Transduction by IGF-1, but not TGF-α or EGF, Augments Pancreatic β-Cell Proliferation
2002
A specific increased expression of insulin receptor substrate 2 in pancreatic beta-cell lines is involved in mediating serum-stimulated beta-cell growth.
1998
The Trp64Arg Polymorphism of the β 3-Adrenergic Receptor Gene Is Not Associated with Obesity or Type 2 Diabetes Mellitus in a Large Population-Based Caucasian Cohort
1998