Citation Impact
Citing Papers
GPCR Engineering Yields High-Resolution Structural Insights into β 2 -Adrenergic Receptor Function
2007 StandoutScienceNobel
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
2003 StandoutScienceNobel
A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling
2007 StandoutNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
β-Arrestin-dependent Constitutive Internalization of the Human Chemokine Decoy Receptor D6
2004 StandoutNobel
The human olfactory receptor gene family
2004 StandoutNobel
Receptor-specific Ubiquitination of β-Arrestin Directs Assembly and Targeting of Seven-transmembrane Receptor Signalosomes
2005 StandoutNobel
Association of β-Arrestin with G Protein-coupled Receptors during Clathrin-mediated Endocytosis Dictates the Profile of Receptor Resensitization
1999
Protein Kinase A and G Protein-coupled Receptor Kinase Phosphorylation Mediates β-1 Adrenergic Receptor Endocytosis through Different Pathways
2003 StandoutNobel
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
Two aromatic residues regulate the response of the human oxytocin receptor to the partial agonist arginine vasopressin
1996
Molecular cloning and functional characterization of V2 [8‐lysine] vasopressin and oxytocin receptors from a pig kidney cell line
1993
Molecular neurobiology and pharmacology of the Vasopressin/Oxytocin receptor family
1995
Oxytocin receptors expressed and coupled to Ca2+signalling in a human vascular smooth muscle cell line
1996
The Highly Conserved DRY Motif of Class A G Protein-Coupled Receptors: Beyond the Ground State
2006
Transient Phosphorylation of the V1a Vasopressin Receptor
1998
Structural bases of vasopressin/oxytocin receptor function
1998
O-Glycosylation of the V2 vasopressin receptor
1999
Regulation of V2 Vasopressin Receptor Degradation by Agonist-promoted Ubiquitination
2003 StandoutNobel
Palmitoylation of the V2 Vasopressin Receptor
1997
An extracellular residue determines the agonist specificity of V2 vasopressin receptors
1995
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
2007 StandoutNatureNobel
Involvement of Gs and Gi Proteins in Dual Coupling of the Luteinizing Hormone Receptor to Adenylyl Cyclase and Phospholipase C
1996
Functional Selectivity and Classical Concepts of Quantitative Pharmacology
2006 StandoutNobel
Distribution of olfactory receptor genes in the human genome
1998
The Binding Site of Neuropeptide Vasopressin V1a Receptor
1995
A Novel Interaction between Adrenergic Receptors and the α-Subunit of Eukaryotic Initiation Factor 2B
1997 StandoutNobel
Ubiquitination of β-Arrestin Links Seven-transmembrane Receptor Endocytosis and ERK Activation
2007 StandoutNobel
Protein Kinase A Anchoring Proteins Are Required for Vasopressin-mediated Translocation of Aquaporin-2 into Cell Membranes of Renal Principal Cells
1999
Phosphorylation and Recycling Kinetics of g Protein-Coupled Receptors
1999
Vasopressin and oxytocin receptors
1996
The Luteinizing Hormone/Chorionic Gonadotropin Receptor Has Distinct Transmembrane Conductors for cAMP and Inositol Phosphate Signals
1996
Activation of the β2-Adrenergic Receptor Involves Disruption of an Ionic Lock between the Cytoplasmic Ends of Transmembrane Segments 3 and 6
2001
Phosphorylation and Desensitization of the Human β1-Adrenergic Receptor
1995 StandoutNobel
Activation Mechanism of Human Oxytocin Receptor: A Combined Study of Experimental and Computer-Simulated Mutagenesis
1999
G Protein-coupled Receptors
1998 StandoutNobel
The Effect of pH on β2 Adrenoceptor Function
2000 StandoutNobel
Teleost isotocin receptor: structure, functional expression, mRNA distribution and phylogeny
1995
Phosphorylation of the Type 1A Angiotensin II Receptor by G Protein-coupled Receptor Kinases and Protein Kinase C
1996 StandoutNobel
Gα15 and Gα16 Couple a Wide Variety of Receptors to Phospholipase C
1995
Trafficking Patterns of β-Arrestin and G Protein-coupled Receptors Determined by the Kinetics of β-Arrestin Deubiquitination
2003 StandoutNobel
Different Single Receptor Domains Determine the Distinct G Protein Coupling Profiles of Members of the Vasopressin Receptor Family
1996
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
A Membrane-proximal Basic Domain and Cysteine Cluster in the C-terminal Tail of CCR5 Constitute a Bipartite Motif Critical for Cell Surface Expression
2001 StandoutNobel
An amino-acid taste receptor
2002 StandoutNature
The Aquaporins, Blueprints for Cellular Plumbing Systems
1998 StandoutNobel
The receptors and cells for mammalian taste
2006 StandoutNature
Molecular mechanisms of membrane receptor desensitization
1993
Phosphorylation and Desensitization of Human Endothelin A and B Receptors
1997 StandoutNobel
The molecular basis of nephrogenic diabetes insipidus
1998
Activation of the Luteinizing Hormone Receptor Following Substitution of Ser-277 with Selective Hydrophobic Residues in the Ectodomain Hinge Region
2000 StandoutNobel
Binding of the β2 Adrenergic Receptor toN-Ethylmaleimide-sensitive Factor Regulates Receptor Recycling
2001 StandoutNobel
Structure of a β1-adrenergic G-protein-coupled receptor
2008 StandoutNatureNobel
Reduced Cell Surface Expression of CCR5 in CCR5Δ32 Heterozygotes Is Mediated by Gene Dosage, Rather Than by Receptor Sequestration
2002 StandoutNobel
Seven-transmembrane receptors
2002 StandoutNobel
Cloning and Functional Characterization of the Amphibian Mesotocin Receptor, a Member of the Oxytocin/Vasopressin Receptor Superfamily
1996
Sequential Binding of Agonists to the β2 Adrenoceptor
2003 StandoutNobel
Evidence for the Involvement of Several Intracellular Domains in the Coupling of Oxytocin Receptor to Gαq/11
1998
Co-expression of Defective Luteinizing Hormone Receptor Fragments Partially Reconstitutes Ligand-induced Signal Generation
1997 StandoutNobel
Regulation of aquaporin-2 water channel trafficking by vasopressin
1997
Molecular Cloning and Pharmacological Characterization of a Molluscan Octopamine Receptor
1997
Protein Kinase A-mediated Phosphorylation of the β2-Adrenergic Receptor Regulates Its Coupling to Gs and Gi
2002 StandoutNobel
Mutation of a Highly Conserved Aspartic Acid in the β2Adrenergic Receptor: Constitutive Activation, Structural Instability, and Conformational Rearrangement of Transmembrane Segment 6
1999
Co-evolution of Ligand-Receptor Pairs in the Vasopressin/Oxytocin Superfamily of Bioactive Peptides
1996
Agonist and Antagonist-Dependent Internalization of the Human Vasopressin V2Receptor
1998
Transmembrane Regions V and VI of the Human Luteinizing Hormone Receptor Are Required for Constitutive Activation by a Mutation in the Third Intracellular Loop
1996 StandoutNobel
The Stability of the G Protein-coupled Receptor-β-Arrestin Interaction Determines the Mechanism and Functional Consequence of ERK Activation
2003 StandoutNobel
β-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking
2001 StandoutNobel
Nephrogenic Diabetes Insipidus
2001
Molecular Endocrinology of the Oxytocin Receptor.
1995
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering
2001 StandoutNobel
Naturally Occurring Mutations of the Luteinizing-Hormone Receptor: Lessons Learned about Reproductive Physiology and G Protein–Coupled Receptors
1999
Regulation of Receptor Fate by Ubiquitination of Activated β 2 -Adrenergic Receptor and β-Arrestin
2001 StandoutScienceNobel
Structure and chromosomal localization of the human antidiuretic hormone receptor gene.
1992
Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
2003 StandoutNobel
The Effect of Mutations in the DRY Motif on the Constitutive Activity and Structural Instability of the Histamine H2 Receptor
2000
Functional rescue of mutant V2 vasopressin receptors causing nephrogenic diabetes insipidus by a co-expressed receptor polypeptide.
1996
Identification of a Motif in the Carboxyl Terminus of β-Arrestin2 Responsible for Activation of JNK3
2001 StandoutNobel
The Oxytocin Receptor
1999
Structure, characterization, and expression of the rat oxytocin receptor gene.
1995
Role of the Third Intracellular Loop for the Activation of Gonadotropin Receptors
1999
Sequence-specific "gene signatures" can beobtained by PCR with single specific primers at low stringency.
1994
Properties of the human arginine vasopressin V2 receptor after site-directed mutagenesis of its putative palmitoylation site
1996
FUNCTIONAL AND STRUCTURAL COMPLEXITY OF SIGNAL TRANSDUCTION VIA G-PROTEIN-COUPLED RECEPTORS
1997
Agonist-induced conformational changes in the G-protein-coupling domain of the β 2 adrenergic receptor
2001 StandoutNobel
Minireview: Mutations and Diseases of G Protein Coupled Receptors
1995
Rat testicular myoid cells express vasopressin receptors: receptor structure, signal transduction, and developmental regulation.
1995
The mouse olfactory receptor gene family
2004 StandoutNobel
Expression of the Oxytocin and Vasopressin Genes
1992
Mutational Analysis of the Highly Conserved Arginine within the Glu/Asp-Arg-Tyr Motif of the α1b-Adrenergic Receptor: Effects on Receptor Isomerization and Activation
2000
Mutational analysis of the highly conserved arginine within the Glu/Asp-Arg-Tyr motif of the alpha(1b)-adrenergic receptor: effects on receptor isomerization and activation.
2000
A serine cluster prevents recycling of the V2 vasopressin receptor
1998
Constitutively active mutants of the alpha 1B-adrenergic receptor: role of highly conserved polar amino acids in receptor activation.
1996
Molecular Properties and Regulation of G-Protein-Coupled Receptors
1994
Tyr115 is the key residue for determining agonist selectivity in the V1a vasopressin receptor.
1995
Structural organization of the human oxytocin receptor gene.
1994
The Oxytocin Receptor System: Structure, Function, and Regulation
2001 Standout
The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex
2009 StandoutNobel
A nuclear 'fossil' of the mitochondrial D-loop and the origin of modern humans
1995 StandoutNatureNobel
Constitutive arrestin-mediated desensitization of a human vasopressin receptor mutant associated with nephrogenic diabetes insipidus
2000
Changes in IP3 and cytosolic Ca2+ in response to sugars and non‐sugar sweeteners in transduction of sweet taste in the rat.
1996
V2R Structure and Diabetes Insipidus
2002
The effect of eight V2 vasopressin receptor mutations on stimulation of adenylyl cyclase and binding to vasopressin.
1994
G-protein-coupled Receptor (GPCR) Kinase Phosphorylation and β-Arrestin Recruitment Regulate the Constitutive Signaling Activity of the Human Cytomegalovirus US28 GPCR
2003 StandoutNobel
Conservation of sequence and structure flanking the mouse and human β-globin loci: The β-globin genes are embedded within an array of odorant receptor genes
1999 StandoutNobel
Mutational analysis and molecular modeling of the nonapeptide hormone binding domains of the [Arg8]vasotocin receptor.
1996
ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling
2003 StandoutScienceNobel
Transgenic rats reveal functional conservation of regulatory controls between the Fugu isotocin and rat oxytocin genes
1997 StandoutNobel
Activation of a heterologously expressed octopamine receptor coupled only to adenylyl cyclase produces all the features of presynaptic facilitation inAplysiasensory neurons
2000 StandoutNobel
Works of S Gilbert being referenced
Molecular cloning of the receptor for human antidiuretic hormone
1992 Nature
Nephrogenic diabetes insipidus. A V2 vasopressin receptor unable to stimulate adenylyl cyclase
1993
Dual signaling potential is common among Gs-coupled receptors and dependent on receptor density.
1994
An extracellular congenital nephrogenic diabetes insipidus mutation of the vasopressin receptor reduces cell surface expression, affinity for ligand, and coupling to the Gs/adenylyl cyclase system.
1994
Desensitization of the human V2 vasopressin receptor. Homologous effects in the absence of heterologous desensitization.
1992
Mutations in the vasopressin V2 receptor gene in families with nephrogenic diabetes insipidus and functional expression of the Q-2 mutant.
1994