Citation Impact
Citing Papers
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor
1991 Standout
A Novel Subtype of the Prostacyclin Receptor Expressed in the Central Nervous System
1996 StandoutNobel
Initial interaction of herpes simplex virus with cells is binding to heparan sulfate
1989 Standout
Cyclooxygenase Isozymes: The Biology of Prostaglandin Synthesis and Inhibition
2004 Standout
15-Deoxy-Δ12,14-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
1995 Standout
Bowel Disorders
2016 Standout
Hypothalamic regulation of sleep and circadian rhythms
2005 StandoutNature
A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP
1991 Standout
Effects of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation or Chronic Constipation: A Meta-analysis
2013
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Prostaglandin D2 formation and characterization of its synthetases in various tissues of adult rats
1988
The second PGD2 receptor CRTH2: structure, properties, and functions in leukocytes
2003
High density of prostaglandin E2 binding sites in the anterior wall of the 3rd ventricle: a possible site of its hyperthermic action
1990
Nociceptive Signals Induce Trafficking of TRPA1 to the Plasma Membrane
2009 StandoutNobel
Glycosylation in Cellular Mechanisms of Health and Disease
2006 Standout
Expression of COX-2 by Normal and Reactive Astrocytes in the Adult Rat Central Nervous System
1999
Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides
1996 StandoutNature
Piezo proteins are pore-forming subunits of mechanically activated channels
2012 StandoutNatureNobel
Extracellular Proteins Organize the Mechanosensory Channel Complex in C. elegans Touch Receptor Neurons
2004 StandoutNobel
Characterization of glycoproteins and their associated oligosaccharides through the use of endoglycosidases
1989
Translocation of phospholipase A2 from cytosol to membranes in rat brain induced by calcium ions
1990
Interleukin-6 expression and regulation in astrocytes
1999
The biology and pharmacology of PGD2
1988
Mechanically Activated Ion Channels
2015 StandoutNobel
Antibody neutralization and escape by HIV-1
2003 StandoutNature
Arachidonic Acid Cascade and Signal Transduction
1990
Distinct localization of prostaglandin D2, E2, and F2α binding sites in monkey brain
1989
Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives
1990 Nature
Lubiprostone
2006
Glial and neuronal control of brain blood flow
2010 StandoutNature
Pentosan polysulfate‐induced thrombocytopenia and thrombosis
1994
Narcolepsy in orexin Knockout Mice
1999 Standout
Adhesion receptors of the immune system
1990 StandoutNature
How were new medicines discovered?
2011 Standout
Crystal structure of an HIV-binding recombinant fragment of human CD4
1990 StandoutNatureNobel
Lubiprostone: chronic constipation and irritable bowel syndrome with constipation
2008
Major Depressive Disorder
2008 Standout
The cyclooxygenase-2 inhibitor celecoxib has therapeutic effects in major depression: results of a double-blind, randomized, placebo controlled, add-on pilot study to reboxetine
2006
Biochemistry and molecular cell biology of diabetic complications
2001 StandoutNature
Golgi Localization of Carbohydrate Sulfotransferases Is a Determinant of L-selectin Ligand Biosynthesis
2003 StandoutNobel
Chloride channels as drug targets
2008
Effects of caffeine and paracetamol alone or in combination with acetylsalicylic acid on prostaglandin E2 synthesis in rat microglial cells
2000
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation
1995 Standout
Characterization of inducible cyclooxygenase in rat brain
1995
Mapping of prostaglandin E2 binding sites in rat brain using quantitative autoradiography
1992
Expression of inducible cyclooxygenase mRNA in the mouse brain after systemic administration of bacterial lipopolysaccharide
1996
Lubiprostone
2009
American College of Gastroenterology Monograph on the Management of Irritable Bowel Syndrome and Chronic Idiopathic Constipation
2014
Sleep–waking discharge patterns of ventrolateral preoptic/anterior hypothalamic neurons in rats
1998
Cell surface modification by endo-beta-galactosidase. Change of blood group activities and release of oligosaccharides from glycoproteins and glycosphingolipids of human erythrocytes.
1979
HIV-1 Integrase: High-Level Production and Screening Assay for the Endonucleolytic Activity
1992
Irritable Bowel Syndrome
2015 Standout
Activation of Ventrolateral Preoptic Neurons During Sleep
1996 Science
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Identification, purification, and partial characterization of a novel Mr 28,000 integral membrane protein from erythrocytes and renal tubules.
1988 StandoutNobel
Molecular Targets for AIDS Therapy
1990 Science
Use of endo- and exoglycosidases for structural studies of glycoconjugates
1979
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.
1994 StandoutNobel
Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor
1992 StandoutScience
Structure Determination of an Endogenous Sleep-Inducing Lipid, cis-9-Octadecenamide (Oleamide): A Synthetic Approach to the Chemical Analysis of Trace Quantities of a Natural Product
1996
Sulphated Sugar Alpha-Cyclodextrin Sulphate, a Uniquely Potent Anti-HIV Agent, Also Exhibits Marked Synergism with AZT, and Lymphoproliferative Activity
1990
Mammalian beta-adrenergic receptors. Structural differences in beta 1 and beta 2 subtypes revealed by peptide maps.
1983 StandoutNobel
Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C
1992 StandoutScience
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Targeted metabolic labeling of yeast N-glycans with unnatural sugars
2010 StandoutNobel
Structure of a Covalently Trapped Catalytic Complex of HIV-1 Reverse Transcriptase: Implications for Drug Resistance
1998 StandoutScience
Cyclodextrin Drug Carrier Systems
1998 Standout
Prostaglandin E2 exerts an awaking effect in the posterior hypothalamus at a site distinct from that mediating its febrile action in the anterior hypothalamus
1992
Cell surface receptors, virus entry and tropism of primate lentiviruses
2002
Mammalian beta-adrenergic receptors. Distinct glycoprotein populations containing high mannose or complex type carbohydrate chains.
1984 StandoutNobel
The role of cytosolic and membrane factors in processing of the human beta-2 adrenergic receptor following translocation and glycosylation in a cell-free system.
1990 StandoutNobel
Inflammatory Blockade Restores Adult Hippocampal Neurogenesis
2003 StandoutScience
9-Deoxy-delta 9, delta 12-13,14-dihydroprostaglandin D2, a metabolite of prostaglandin D2 formed in human plasma.
1984
Oligomeric Modeling and Electrostatic Analysis of the gp120 Envelope Glycoprotein of Human Immunodeficiency Virus
2000
Modulation by prostaglandin D2 of mitral cell responses to odor stimulation in rabbit olfactory bulb
1986
Effect of endo-beta-galactosidase on intact human erythrocytes.
1979
Genetic contributions to generalized arousal of brain and behavior
2003 StandoutNobel
Molecular Basis of Mechanotransduction in Living Cells
2001
Modified Cyclodextrin Sulphates(mCDS11) have Potent Inhibitory Activity against HIV and High Oral Bioavailability
1994
Involvement of a Leukocyte Adhesion Receptor (LFA-1) in HIV-Induced Syncytium Formation
1989 Science
A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells.
1993 StandoutNobel
Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination
2021 Standout
Sleep-wake regulation by prostaglandins D2 and E2.
1988
Autoradiographic localization of a binding protein(s) specific for prostaglandin D2 in rat brain.
1983
Role of N-linked glycans in the interaction between the envelope glycoprotein of human immunodeficiency virus and its CD4 cellular receptor. Structural enzymatic analysis.
1989 StandoutNobel
Mechanism by which the lectin actinohivin blocks HIV infection of target cells
2009 StandoutNobel
Inhibitors of human immunodeficiency virus integrase.
1993 StandoutNobel
Inflammatory factors stimulate expression of group II phospholipase A2 in rat cultured astrocytes. Two distinct pathways of the gene expression
1991
Chemical Characterization of a Family of Brain Lipids That Induce Sleep
1995 Science
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Postnatal changes in the localization of prostaglandin D synthetase from neurons to oligodendrocytes in the rat brain.
1987
Synthesis and Anti-HIV Activities of Glutamate and Peptide Conjugates of Nucleoside Reverse Transcriptase Inhibitors
2012
Prevention of HIV-1 Infection and Preservation of CD4 Function by the Binding of CPFs to gp120
1990 Science
Complex-type N-linked oligosaccharides of gp120 from human immunodeficiency virus type 1 contain sulfated N-acetylglucosamine
1993
DYNAMIC O-LINKED GLYCOSYLATION OF NUCLEAR AND CYTOSKELETAL PROTEINS
1997
Chemical Implications for Antitumor and Antiviral Prostaglandins: Reaction of Δ7-Prostaglandin A1 and Prostaglandin A1 Methyl Esters with Thiols
1997 StandoutNobel
Aquaporin-6: An intracellular vesicle water channel protein in renal epithelia
1999 StandoutNobel
Works of Ryuji Ueno being referenced
Safety and patient outcomes with lubiprostone for up to 52 weeks in patients with irritable bowel syndrome with constipation
2012
Little sleep-promoting effect of three sleep substances diurnally infused in unrestrained rats
1984
A synthetic prostone activates apical chloride channels in A6 epithelial cells
2008
Clinical trial: lubiprostone in patients with constipation‐associated irritable bowel syndrome – results of two randomized, placebo‐controlled studies
2008
Awaking effect of PGE2 microinjected into the preoptic area of rats
1988
Increased level of salivary prostaglandins in patients with major depression
1988
Suppression of sleep by prostaglandin synthesis inhibitors in unrestrained rats
1988
Effect of a selective chloride channel activator, lubiprostone, on gastrointestinal transit, gastric sensory, and motor functions in healthy volunteers
2006
Purification and properties of neutral β-N-acetylglycosaminidase from carp blood
1991
Muramyl dipeptide-elicited production of PGD2 from astrocytes in culture
1988
Awaking effect of prostaglandin E2 in freely moving rats
1989
Clinical trial: phase 2 study of lubiprostone for irritable bowel syndrome with constipation
2008
SPI-0211 activates T84 cell chloride transport and recombinant human ClC-2 chloride currents
2004
Efficacy and Safety of Lubiprostone in Patients with Chronic Constipation
2009
Effects of lubiprostone on human uterine smooth muscle cells
2008
Recovery of mucosal barrier function in ischemic porcine ileum and colon is stimulated by a novel agonist of the ClC-2 chloride channel, lubiprostone
2006
Multicenter, 4-Week, Double-Blind, Randomized, Placebo-Controlled Trial of Lubiprostone, a Locally-Acting Type-2 Chloride Channel Activator, in Patients With Chronic Constipation
2007
Lubiprostone, a locally acting chloride channel activator, in adult patients with chronic constipation: a double‐blind, placebo‐controlled, dose‐ranging study to evaluate efficacy and safety
2007
S1272 Lubiprostone Is Effective and Well Tolerated Through 48 Weeks of Treatment in Adults with Irritable Bowel Syndrome and Constipation
2008
Phase III Study of Lubiprostone, a Chloride Channel-2 (ClC-2) Activator for the Treatment of Constipation
2005
Changes of Enzymes Involved in Prostaglandin Metabolism and Prostaglandin Binding Proteins in Rat Brain During Development and Aging
1985
Effects of Lubiprostone, a Novel GI Chloride Channel Activator, on Isolated Smooth Muscle
2005
Lubiprostone Significantly Improves Symptom Relief Rates in Adults With Irritable Bowel Syndrome and Constipation (IBS-C): Data from Two Twelve-Week, Randomized, Placebo-Controlled, Double-Blind Trials
2007
Prostaglandin D2 induces sleep when microinjected into the preoptic area of conscious rats
1982
Effects of Lubiprostone, a Novel GI Chloride Channel Activator, on Reproductive and Developmental Toxicity Endpoints in Rats
2005
Dextran Sulfate Suppression of Viruses in the HIV Family: Inhibition of Virion Binding to CD4 + Cells
1988 Science
Enzymatic Degradation of Whale Cartilage Keratosulfate-III
1970
Enzymatic Degradation of Whale Cartilage Keratosulfate-I
1970
Alterations in nociception after intracisternal administration of prostaglandin D2, E2 or F2α to conscious mice
1986
Initial and Sustained Effects of Lubiprostone, a Chloride Channel-2 (ClC-2) Activator for the Treatment of Constipation
2005
Phase III efficacy and safety of RU-0211, a novel chloride channel activator, for the treatment of constipation
2003