Citation Impact
Citing Papers
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Nucleic acid detection with CRISPR-Cas13a/C2c2
2017 StandoutScience
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
De novo design and directed folding of disulfide-bridged peptide heterodimers
2022 StandoutNobel
Improved gRNA secondary structures allow editing of target sites resistant to CRISPR-Cas9 cleavage
2022 StandoutNobel
The CRISPR tool kit for genome editing and beyond
2018
Stabilization of Foxp3 expression by CRISPR-dCas9-based epigenome editing in mouse primary T cells
2017
Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee
2020 Standout
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Switchable Cas9
2017 StandoutNobel
Orthogonal Genetic Regulation in Human Cells Using Chemically Induced CRISPR/Cas9 Activators
2017
Guide-bound structures of an RNA-targeting A-cleaving CRISPR–Cas13a enzyme
2017 StandoutNobel
dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
2022 StandoutNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
2019 StandoutNobel
Perturbing proteomes at single residue resolution using base editing
2020
Genome-wide CRISPR-Cas9 screening in mammalian cells
2019
Functional Genetic Variants Revealed by Massively Parallel Precise Genome Editing
2018
A tunable orthogonal coiled-coil interaction toolbox for engineering mammalian cells
2020
In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation
2017
Complex transcriptional modulation with orthogonal and inducible dCas9 regulators
2016
Hydrophobic mismatch drives self-organization of designer proteins into synthetic membranes
2024 StandoutNobel
Multi-input chemical control of protein dimerization for programming graded cellular responses
2019 StandoutNobel
Am I ready for CRISPR? A user's guide to genetic screens
2017
A CRISPR–dCas Toolbox for Genetic Engineering and Synthetic Biology
2018
Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs
2017
Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects
2020 Standout
Genetic engineering of T cells for immunotherapy
2021
Inducible and multiplex gene regulation using CRISPR–Cpf1-based transcription factors
2017
Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection
2018 StandoutNobel
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions
2018 StandoutNobel
An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance
2018
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
RNA Targeting by Functionally Orthogonal Type VI-A CRISPR-Cas Enzymes
2017 StandoutNobel
Controlling and enhancing CRISPR systems
2020 StandoutNobel
Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system
2017
Crossing enhanced and high fidelity SpCas9 nucleases to optimize specificity and cleavage
2017
Engineering Synthetic Signaling Pathways with Programmable dCas9-Based Chimeric Receptors
2017
Diversity and evolution of class 2 CRISPR–Cas systems
2017
High-Throughput Approaches to Pinpoint Function within the Noncoding Genome
2017
A Broad-Spectrum Inhibitor of CRISPR-Cas9
2017 StandoutNobel
Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
2020 StandoutNobel
CRISPR/Cas9-Based Engineering of the Epigenome
2017
Mechanism-Based Precision Therapy for the Treatment of Primary Immunodeficiency and Primary Immunodysregulatory Diseases
2019
Transcriptional regulation with CRISPR-Cas9: principles, advances, and applications
2016
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
<p>Drug-free mannosylated liposomes inhibit tumor growth by promoting the polarization of tumor-associated macrophages</p>
2019
Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches
2020 StandoutNobel
Accessing the Phenotype Gap: Enabling Systematic Investigation of Paralog Functional Complexity with CRISPR
2017
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
A thermostable Cas9 with increased lifetime in human plasma
2017 StandoutNobel
The next generation of CRISPR–Cas technologies and applications
2019
Broad-spectrum enzymatic inhibition of CRISPR-Cas12a
2019 StandoutNobel
Macrophage M1/M2 polarization
2020 Standout
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
De novo design of tyrosine and serine kinase-driven protein switches
2021 StandoutNobel
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Deacetylated sialic acids modulates immune mediated cytotoxicity via the sialic acid-Siglec pathway
2021 StandoutNobel
A Toolkit for Rapid Modular Construction of Biological Circuits in Mammalian Cells
2019
CRISPR/Cas9 for cancer research and therapy
2018
Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6
2018 StandoutScience
CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine
2017
Systematic discovery of natural CRISPR-Cas12a inhibitors
2018 StandoutScienceNobel
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
Baicalein suppress EMT of breast cancer by mediating tumor-associated macrophages polarization.
2018
The chemistry of Cas9 and its CRISPR colleagues
2017 StandoutNobel
CRISPR-CasΦ from huge phages is a hypercompact genome editor
2020 StandoutScienceNobel
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
Traditional Chinese medicine as a cancer treatment: Modern perspectives of ancient but advanced science
2019 Standout
Loss of TET proteins in regulatory T cells promotes abnormal proliferation, Foxp3 destabilization and IL-17 expression
2019 StandoutNobel
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
CRISPOR: intuitive guide selection for CRISPR/Cas9 genome editing experiments and screens
2018 Standout
CRISPR-Cas in Streptococcus pyogenes
2019 StandoutNobel
CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks
2020 StandoutNobel
Cas9 versus Cas12a/Cpf1: Structure–function comparisons and implications for genome editing
2018
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation
2016
Works of Ryan J. Cecchi being referenced
Mimicking the tumor microenvironment to regulate macrophage phenotype and assessing chemotherapeutic efficacy in embedded cancer cell/macrophage spheroid models
2016
Comparison of Cas9 activators in multiple species
2016
An enhanced CRISPR repressor for targeted mammalian gene regulation
2018
High-throughput creation and functional profiling of DNA sequence variant libraries using CRISPR–Cas9 in yeast
2018