Citation Impact
Citing Papers
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
Generic membrane-spanning features endow IRE1α with responsiveness to membrane aberrancy
2017
CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells
2016 Science
2019
Improved gRNA secondary structures allow editing of target sites resistant to CRISPR-Cas9 cleavage
2022 StandoutNobel
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Single-cell analysis of a mutant library generated using CRISPR-guided deaminase in human melanoma cells
2020
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Inference and analysis of cell-cell communication using CellChat
2021 Standout
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
2019 StandoutNobel
Challenges and emerging directions in single-cell analysis
2017
Mechanisms, regulation and functions of the unfolded protein response
2020 Standout
The Biogenesis, Functions, and Challenges of Circular RNAs
2018 Standout
A view on drug resistance in cancer
2019 StandoutNature
Molecular Architecture of the Mouse Nervous System
2018 Standout
Single-cell-resolution transcriptome map of human, chimpanzee, bonobo, and macaque brains
2020 StandoutNobel
Fast, sensitive and accurate integration of single-cell data with Harmony
2019 Standout
A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic Screens
2019
The Hyaluronidase, TMEM2, Promotes ER Homeostasis and Longevity Independent of the UPRER
2019
Scrublet: Computational Identification of Cell Doublets in Single-Cell Transcriptomic Data
2019
Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element
2018
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response
2017
Genetic interaction networks in cancer cells
2019
A CRISPR–dCas Toolbox for Genetic Engineering and Synthetic Biology
2018
FUS(1-359) transgenic mice as a model of ALS: pathophysiological and molecular aspects of the proteinopathy
2018
Hallmarks of aging: An expanding universe
2023 Standout
Multiplexed droplet single-cell RNA-sequencing using natural genetic variation
2017
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
2022 Standout
Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain
2018
Effective gene expression prediction from sequence by integrating long-range interactions
2021 StandoutNobel
CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions
2018 StandoutNobel
A CRISPR toolbox to study virus–host interactions
2017
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
Controlling and enhancing CRISPR systems
2020 StandoutNobel
Hacking the Cancer Genome: Profiling Therapeutically Actionable Long Non-coding RNAs Using CRISPR-Cas9 Screening
2019
New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer
2018 Standout
Cancer stem cells revisited
2017 Standout
Integrating single-cell transcriptomic data across different conditions, technologies, and species
2018 Standout
The Histone Chaperone FACT Induces Cas9 Multi-turnover Behavior and Modifies Genome Manipulation in Human Cells
2020
LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation
2021 StandoutNobel
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
The single-cell transcriptional landscape of mammalian organogenesis
2019 StandoutNature
CRISPR interference-based specific and efficient gene inactivation in the brain
2018
Synthetic lethality as an engine for cancer drug target discovery
2019
High-Throughput Approaches to Pinpoint Function within the Noncoding Genome
2017
Multimodal biomedical AI
2022 Standout
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes
2020 Standout
The Unfolded Protein Response: Detecting and Responding to Fluctuations in the Protein-Folding Capacity of the Endoplasmic Reticulum
2019
Revealing the human mucinome
2022 StandoutNobel
CRISPR/Cas9-Based Engineering of the Epigenome
2017
CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis
2017
Deconstructing cerebellar development cell by cell
2020
Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage
2019 Standout
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches
2020 StandoutNobel
Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis
2021
Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies
2020
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Pooled CRISPR screening with single-cell transcriptome readout
2017
A new era in functional genomics screens
2021
Synthetic lethality and cancer
2017
Optical Pooled Screens in Human Cells
2019
The Current State and Future of CRISPR-Cas9 gRNA Design Tools
2018
Massively parallel single-nucleus RNA-seq with DroNc-seq
2017
De novo design of tyrosine and serine kinase-driven protein switches
2021 StandoutNobel
Integrative single-cell analysis
2019
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Comprehensive Integration of Single-Cell Data
2019 Standout
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Massively parallel kinetic profiling of natural and engineered CRISPR nucleases
2020 StandoutNobel
Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens
2016
The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1
2018
Deacetylated sialic acids modulates immune mediated cytotoxicity via the sialic acid-Siglec pathway
2021 StandoutNobel
A Toolkit for Rapid Modular Construction of Biological Circuits in Mammalian Cells
2019
3D Brain Organoids: Studying Brain Development and Disease Outside the Embryo
2020
Dynamic changes in complexes of IRE1α, PERK, and ATF6α during endoplasmic reticulum stress
2018
CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine
2017
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
The Human Cell Atlas
2017
Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development
2022 StandoutNobel
A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma
2017 Nature
Genome-wide association studies
2021
The STRING database in 2023: protein–protein association networks and functional enrichment analyses for any sequenced genome of interest
2022 Standout
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
CRISPOR: intuitive guide selection for CRISPR/Cas9 genome editing experiments and screens
2018 Standout
CRISPRi is not strand-specific at all loci and redefines the transcriptional landscape
2017
Works of Ryan A. Pak being referenced
Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis
2016
A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response
2016
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation
2016