Citation Impact
Citing Papers
Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application
2006
Human induced pluripotent stem cells and their use in drug discovery for toxicity testing
2013
Thermodynamics of Heat Activation of Single Capsaicin Ion Channels VR1
2003
The Role of Neural Inflammation in Asthma and Chronic Obstructive Pulmonary Disease
2003
Molecular Basis for Tissue Expansion: Clinical Implications for the Surgeon
1998
A multi-substrate screening approach for the identification of a broadly applicable Diels–Alder catalyst
2019 StandoutNobel
Ginseng pharmacology
1999 Standout
G protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation
2004 StandoutNobel
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
Mechanotransduction and extracellular matrix homeostasis
2014 Standout
Naphtho[2,1-b][1,5] and [1,2-f][1,4]oxazocines as selective NK1 antagonists
2004
Abnormal Cell Calcium Homeostasis in Type 2 Diabetes Mellitus: A New Look on Old Disease
1999
Network pharmacology: the next paradigm in drug discovery
2008 Standout
Cellular and molecular pathobiology of pulmonary arterial hypertension
2004 Standout
The effect of membrane cholesterol content on ion transport processes in plasma membranes
1997
Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy
2009 Standout
Cellular Cholesterol Efflux Mediated by Cyclodextrins
1995 Standout
Molecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin
2016 Standout
A tense situation: forcing tumour progression
2009 Standout
The development of allergic inflammation
2008 StandoutNature
Glial and neuronal control of brain blood flow
2010 StandoutNature
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
T-Type Ca2+ Channels and Pharmacological Blockade: Potential Pathophysiological Relevance
1997
Mechanosensitive TRP channels in cardiovascular pathophysiology
2009
Hypoxia inducible factor-1-dependent up-regulation of BMP4 mediates hypoxia-induced increase of TRPC expression in PASMCs
2015 StandoutNobel
Endothelin type A receptor antagonist normalizes blood pressure in rats exposed to eucapnic intermittent hypoxia
2008
Industrial Applications of the Diels–Alder Reaction
2013
Vanilloid Receptor–Related Osmotically Activated Channel (VR-OAC), a Candidate Vertebrate Osmoreceptor
2000 Standout
The Gap Junction Communication Channel
1996 Standout
Static Pressure Regulates Connective Tissue Growth Factor Expression in Human Mesangial Cells
2001
Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain
2010 StandoutNobel
Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six
2014 StandoutNobel
Endothelin-1 mediates hypoxia-induced inhibition of voltage-gated K+ channel expression in pulmonary arterial myocytes
2007 StandoutNobel
Connections with Connexins: the Molecular Basis of Direct Intercellular Signaling
1996 Standout
International Union of Pharmacology. XLVII. Nomenclature and Structure-Function Relationships of Voltage-Gated Sodium Channels
2005 Standout
Mechanisms and function of intercellular calcium signaling
1994
An analysis of the attrition of drug candidates from four major pharmaceutical companies
2015 Standout
Heterogeneity of Vascular Endothelial Cells in Normal and Disease States
1998
Direct Activation of K Ca Channel in Airway Smooth Muscle by Nitric Oxide: Involvement of a Nitrothiosylation Mechanism?
1998
Relaxing Effects of NO Donors on Guinea Pig Trachea In Vitro are Mediated by Calcium-Sensitive Potassium Channels
1998
Inhibition of voltage-gated K+currents by endothelin-1 in human pulmonary arterial myocytes
2001
Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis.
1992 StandoutNobel
Activation of H2O2 by Chiral Confined Brønsted Acids: A Highly Enantioselective Catalytic Sulfoxidation
2012 StandoutNobel
pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures
2015 Standout
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
2001 Standout
Scalable and Highly Diastereo- and Enantioselective Catalytic Diels–Alder Reaction of α,β-Unsaturated Methyl Esters
2018 StandoutNobel
The Role of Vitamin D and Calcium in Type 2 Diabetes. A Systematic Review and Meta-Analysis
2007 Standout
Global gene expression of cells attached to a tissue engineering scaffold
2004 StandoutNobel
Endocrine and Paracrine Regulation of Birth at Term and Preterm*
2000 Standout
A critical assessment of modeling safety-related drug attrition
2013
Differential Activation of Cardiac c-Jun Amino-Terminal Kinase and Extracellular Signal-Regulated Kinase in Angiotensin II–Mediated Hypertension
1998 StandoutNobel
Lowering the cholesterol content of MA104 cells inhibits receptor-mediated transport of folate.
1992
Catalytic Asymmetric [4+2]-Cycloaddition of Dienes with Aldehydes
2017 StandoutNobel
Hypoxic Pulmonary Vasoconstriction
2012
A role for phospholipase C activity but not ryanodine receptors in the initiation and propagation of intercellular calcium waves
1995
Natriuretic Peptides, Their Receptors, and Cyclic Guanosine Monophosphate-Dependent Signaling Functions
2005 Standout
CELLULAR AND MOLECULAR MECHANISMS OF PULMONARY VASCULAR REMODELING
1997
Partial HIF-1α deficiency impairs pulmonary arterial myocyte electrophysiological responses to hypoxia
2001 StandoutNobel
Mechanobiology of force transduction in dermal tissue
2003
Chronic hypoxia alters effects of endothelin and angiotensin on K+currents in pulmonary arterial myocytes
1999
Hypercholesterolemia and atherosclerosis change vascular reactivity in rabbits by different mechanisms.
1991
Obstruction of the fetal urinary tract.
1997
Role of cGMP versus 20-HETE in the vasodilator response to nitric oxide in rat cerebral arteries
2000
Mechanical force-induced signal transduction in lung cells
1999
Effect of chronic hypoxia on agonist-induced tone and calcium signaling in rat pulmonary artery
2001
Asymmetric Counteranion‐Directed Iron Catalysis: A Highly Enantioselective Sulfoxidation
2012 StandoutNobel
Pathophysiology of Sleep Apnea
2010 Standout
Applications of Catalytic Asymmetric Sulfide Oxidations to the Syntheses of Biologically Active Sulfoxides
2005
Natriuretic Peptide Receptor-C Regulates Coronary Blood Flow and Prevents Myocardial Ischemia/Reperfusion Injury
2004
Molecular and cellular basis of pulmonary vascular remodeling in pulmonary hypertension
2002
Ca2+Sensitivity of Smooth Muscle and Nonmuscle Myosin II: Modulated by G Proteins, Kinases, and Myosin Phosphatase
2003 Standout
Assessing Atropisomer Axial Chirality in Drug Discovery and Development
2011 Standout
DESENSITIZATION OF G PROTEIN–COUPLED RECEPTORS AND NEURONAL FUNCTIONS
2004 StandoutNobel
Microglial M1/M2 polarization and metabolic states
2015 Standout
Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine/paracrine mechanism.
1993
Purification and characterization of smooth muscle cell caveolae.
1994 StandoutNobel
The Concise Guide to PHARMACOLOGY 2013/14: Catalytic Receptors
2013
Visible‐Light Photocatalysis: Does It Make a Difference in Organic Synthesis?
2018 Standout
Cardiac Mitogen-Activated Protein Kinase Activities Are Chronically Increased in Stroke-Prone Hypertensive Rats
1998 StandoutNobel
Calcium sparks in smooth muscle
2000
Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to Mechanical Loading
2004 Standout
THE CAVEOLAE MEMBRANE SYSTEM
1998 Standout
Ambient Temperature Does not Affect the Tactile Sensitivity of Mystacial Vibrissae in Harbour Seals
1998
Hypoxia Inducible Factor 1 Mediates Hypoxia-Induced TRPC Expression and Elevated Intracellular Ca 2+ in Pulmonary Arterial Smooth Muscle Cells
2006 StandoutNobel
Design and optimization of cyclized NK1 antagonists with controlled atropisomeric properties
2004
Invited Review: Arteriolar smooth muscle mechanotransduction: Ca2+signaling pathways underlying myogenic reactivity
2001
Temporal, spatial, and oxygen-regulated expression of hypoxia-inducible factor-1 in the lung
1998 StandoutNobel
Stretch Induces Mitogen-Activated Protein Kinase Activation and Myogenic Tone Through 2 Distinct Pathways
1999
Works of Russell Bialecki being referenced
Pharmacological Characterization of ZD6021: A Novel, Orally Active Antagonist of the Tachykinin Receptors
2001
Discovery of novel, orally active dual NK1/NK2 antagonists
2001
A framework to assess the translation of safety pharmacology data to humans
2009
Cholesterol enrichment increases basal and agonist-stimulated calcium influx in rat vascular smooth muscle cells.
1991
Stretch increases inositol trisphosphate and inositol tetrakisphosphate in cultured pulmonary vascular smooth muscle cells
1991
ZD1611, an Orally Active Endothelin-A Receptor Antagonist, Prevents Chronic Hypoxia-induced Pulmonary Hypertension in the Rat
1999
Approaches to seizure risk assessment in preclinical drug discovery
2009
A Novel Orally Active Endothelin-A Receptor Antagonist, ZD1611, Prevents Chronic Hypoxia-Induced Pulmonary Hypertension in the Rat
1998
The discovery of non-basic atrial natriuretic peptide clearance receptor antagonists. part 1
2000
Stretching increases calcium influx and efflux in cultured pulmonary arterial smooth muscle cells
1992
Functional comparison of endothelin receptors in human and rat pulmonary artery smooth muscle
1997
Cholesterol-induced changes in rabbit arterial smooth muscle sensitivity to adrenergic stimulation
1989
Cholesterol increases the L-type voltage-sensitive calcium channel current in arterial smooth muscle cells.
1992
KCa channel antagonists reduce NO donor-mediated relaxation of vascular and tracheal smooth muscle
1995
Hypoxic exposure time dependently modulates endothelininduced contraction of pulmonary artery smooth muscle
1998
Ion channels, membrane lipids and cholesterol: a role for membrane lipid domains in arterial function.
1990
Excess membrane cholesterol alters calcium channels in arterial smooth muscle
1989