Citation Impact
Citing Papers
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
MutL traps MutS at a DNA mismatch
2015 StandoutNobel
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
Protein roadblocks and helix discontinuities are barriers to the initiation of mismatch repair
2007 StandoutNobel
Evolution of the Immunoglobulin Heavy Chain Class Switch Recombination Mechanism
2007
Saccharomyces cerevisiae MutLα Is a Mismatch Repair Endonuclease
2007 StandoutNobel
Mismatch Repair-dependent Iterative Excision at Irreparable O6-Methylguanine Lesions in Human Nuclear Extracts
2006 StandoutNobel
Mechanisms in Eukaryotic Mismatch Repair
2006 StandoutNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
X4 and R5 HIV-1 Have Distinct Post-entry Requirements for Uracil DNA Glycosylase during Infection of Primary Cells
2010 StandoutNobel
The biochemistry of activation-induced deaminase and its physiological functions
2012
Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA
2007
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Mechanism of somatic hypermutation: Critical analysis of strand biased mutation signatures at A:T and G:C base pairs
2008
Continuous evolution of base editors with expanded target compatibility and improved activity
2019
Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway
2009 StandoutNobel
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
The MutSα-Proliferating Cell Nuclear Antigen Interaction in Human DNA Mismatch Repair
2008 StandoutNobel
Evolution of the AID/APOBEC Family of Polynucleotide (Deoxy)cytidine Deaminases
2004
Endonucleolytic Function of MutLα in Human Mismatch Repair
2006 StandoutNobel
DNA Deamination in Immunity: AID in the Context of Its APOBEC Relatives
2007
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
MDM2 can interact with the C-terminus of AID but it is inessential for antibody diversification in DT40 B cells
2005
Interferon‐inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replication†
2006
DNA deamination in immunity
2005
Massive APOBEC3 Editing of Hepatitis B Viral DNA in Cirrhosis
2010
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Activation-induced Cytosine Deaminase (AID) Is Actively Exported out of the Nucleus but Retained by the Induction of DNA Breaks
2004
Evolving proteins in mammalian cells using somatic hypermutation
2006 StandoutNobel
Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25
1993 StandoutNatureNobel
AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation
2012
Molecular Mass, Stoichiometry, and Assembly of 20 S Particles
2001 StandoutNobel
Novel Roles for MLH3 Deficiency and TLE6-Like Amplification in DNA Mismatch Repair-Deficient Gastrointestinal Tumorigenesis and Progression
2008 StandoutNobel
The mutation spectrum of purified AID is similar to the mutability index in Ramos cells and in ung?/?msh2?/? mice
2005
Activation-induced cytidine deaminase structure and functions: A species comparative view
2011
The AID/APOBEC family of nucleic acid mutators
2008
Physical and functional interaction of human nuclear uracil-DNA glycosylase with proliferating cell nuclear antigen
2005
Retroviral restriction by APOBEC proteins
2004
TET enzymes, TDG and the dynamics of DNA demethylation
2013 StandoutNature
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Requirement of Non-canonical Activity of Uracil DNA Glycosylase for Class Switch Recombination
2006 StandoutNobel
Transcriptome-wide sequencing reveals numerous APOBEC1 mRNA-editing targets in transcript 3′ UTRs
2011
Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
2015 Standout
MutLα and Proliferating Cell Nuclear Antigen Share Binding Sites on MutSβ
2010 StandoutNobel
Characterization of the Interactome of the Human MutL Homologues MLH1, PMS1, and PMS2
2006
Determinants of sequence-specificity within human AID and APOBEC3G
2010
Activation-induced Cytidine Deaminase Deaminates 5-Methylcytosine in DNA and Is Expressed in Pluripotent Tissues
2004
Functions of MutLα, Replication Protein A (RPA), and HMGB1 in 5′-Directed Mismatch Repair
2009 StandoutNobel
DNA-Dependent Protein Kinase Inhibits AID-Induced Antibody Gene Conversion
2007
Expression of human AID in yeast induces mutations in context similar to the context of somatic hypermutation at G-C pairs in immunoglobulin genes
2005
Biochemical Analysis of Hypermutational Targeting by Wild Type and Mutant Activation-induced Cytidine Deaminase
2004
Mismatch Recognition and Uracil Excision Provide Complementary Paths to Both Ig Switching and the A/T-Focused Phase of Somatic Mutation
2004
Involvement of the β Clamp in Methyl-directed Mismatch Repair in Vitro
2009 StandoutNobel
Immunological, morphological, and electrophysiological variation among retinal ganglion cells purified by panning
1988
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
2010 StandoutNobel
Carboxy-terminal domain of AID required for its mRNA complex formation in vivo
2009 StandoutNobel
Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation
2013 StandoutNobel
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
2016 Standout
Dependence of antibody gene diversification on uracil excision
2007
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
2015 StandoutNobel
Cleavage of members of the synaptobrevin/VAMP family by types D and F botulinal neurotoxins and tetanus toxin.
1994 StandoutNobel
Beyond self-eating: The control of nonautophagic functions and signaling pathways by autophagy-related proteins
2017
Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
2016 StandoutScience
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
The multifaceted roles of RNA binding in APOBEC cytidine deaminase functions
2014
PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance
2010 StandoutNobel
Reward versus Risk: DNA Cytidine Deaminases Triggering Immunity and Disease
2005
A marker of early amacrine cell development in rat retina
1985
Further evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination
2009 StandoutNobel
Immunoglobulin Gene Diversification
2005
APOBEC-Mediated Editing of Viral RNA
2004 Science
Molecular Mechanisms of Antibody Somatic Hypermutation
2007
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
DNA cleavage in immunoglobulin somatic hypermutation depends onde novoprotein synthesis but not on uracil DNA glycosylase
2005 StandoutNobel
RNA editing of hepatitis B virus transcripts by activation-induced cytidine deaminase
2013 StandoutNobel
Dissociation of in vitro DNA deamination activity and physiological functions of AID mutants
2008 StandoutNobel
Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases in vitro and in vivo
2005
Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation
2011 StandoutNobel
Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
2013 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Developing a New Definition and Assessing New Clinical Criteria for Septic Shock
2016 Standout
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
2016 StandoutNobel
Antiviral Protein APOBEC3G Localizes to Ribonucleoprotein Complexes Found in P Bodies and Stress Granules
2006
DNA polymerases and somatic hypermutation of immunoglobulin genes
2005
DNA Polymerase η Contributes to Strand Bias of Mutations of A versus T in Immunoglobulin Genes
2005
AID to overcome the limitations of genomic information
2005 StandoutNobel
Works of Rupert Beale being referenced
The WD 40 domain of ATG 16L1 is required for its non‐canonical role in lipidation of LC 3 at single membranes
2018
A LC3-Interacting Motif in the Influenza A Virus M2 Protein Is Required to Subvert Autophagy and Maintain Virion Stability
2014
Promoting Global Research Excellence in Severe Sepsis (PROGRESS): Lessons from an International Sepsis Registry
2009
Somatic hypermutation at A·T pairs: polymerase error versus dUTP incorporation
2005
Comparison of the Differential Context-dependence of DNA Deamination by APOBEC Enzymes: Correlation with Mutation Spectra in Vivo
2004
Localization of the Thy-1 antigen to the surfaces of rat retinal ganglion cells
1982