Citation Impact
Citing Papers
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Refinement of Structural Leads for Centrally Acting Oxime Reactivators of Phosphylated Cholinesterases
2012 StandoutNobel
In situ click chemistry generation of cyclooxygenase-2 inhibitors
2017 Standout
Carbonic anhydrase inhibitors: synthesis of sulfonamides incorporating dtpa tails and of their zinc complexes with powerful topical antiglaucoma properties
2001
Carbonic anhydrase inhibitors: sulfonamides incorporating furan-, thiophene- and pyrrole-carboxamido groups possess strong topical intraocular pressure lowering properties as aqueous suspensions
2000
Reactions in Droplets in Microfluidic Channels
2006 Standout
Chemical Technologies for Probing Glycans
2006 StandoutNobel
One pot ‘click’ reactions: tandem enantioselective biocatalytic epoxide ring opening and [3+2] azide alkyne cycloaddition
2010 StandoutNobel
Dynamic Covalent Chemistry
2002 StandoutNobel
Phosphoramidite accelerated copper(i)-catalyzed [3 + 2] cycloadditions of azides and alkynes
2009 StandoutNobel
Carbonic anhydrase inhibitors: 4-sulfamoyl-benzenecarboxamides and 4-chloro-3-sulfamoyl-benzenecarboxamides with strong topical antiglaucoma properties
2001
The growing applications of click chemistry
2007 Standout
Cancer nanotechnology: opportunities and challenges
2005 Standout
Recent advancements in surface-enhanced laser desorption/ionization-time of flight-mass spectrometry
2000
Iterative In Situ Click Chemistry Creates Antibody‐like Protein‐Capture Agents
2009 StandoutNobel
Electrospray ionization mass spectrometry in the study of biomolecular non-covalent interactions
1999
Carbonic anhydrase inhibitors. Part 79
1999
Carbonic anhydrase inhibitors – Part 78. Synthesis of water-soluble sulfonamides incorporating β-alanyl moieties, possessing long lasting-intraocular pressure lowering properties via the topical route
2000
The growing impact of click chemistry on drug discovery
2003 StandoutNobel
A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes
2002 StandoutNobel
Amplification of Dynamic Chiral Crown Ether Complexes During Cyclic Acetal Formation
2003 StandoutNobel
Carbonic anhydrase inhibitors
2002 Standout
A Simple Enantioconvergent and Chemoenzymatic Synthesis of Optically Active α‐Substituted Amides
2011 StandoutNobel
Carbonic anhydrase inhibitors: Sulfonamides as antitumor agents?
2001
Interactions with Aromatic Rings in Chemical and Biological Recognition
2003 Standout
Carbonic Anhydrase Inhibitors: Synthesis of Schiff Bases of Hydroxybenzaldehydes with Aromatic Sulfonamides and Their Reactions with Arylsulfonyl Isocyanates
2000
Dynamic Combinatorial Chemistry Employing Boronic Acids/Boronate Esters Leads to Potent Oxygenase Inhibitors
2012 StandoutNobel
Comprehensive survey of chemical libraries yielding enzyme inhibitors, receptor agonists and antagonists, and other biologically active agents: 1992 through 1997
1997
Inhibitors of HIV‐1 Protease by Using In Situ Click Chemistry
2006 StandoutNobel
Click Chemistry In Situ: Acetylcholinesterase as a Reaction Vessel for the Selective Assembly of a Femtomolar Inhibitor from an Array of Building Blocks
2002 StandoutNobel
Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry
2014 StandoutNobel
Application of Fourier transform ion cyclotron resonance mass spectrometry to oligosaccharides
2004
Organic Azides: An Exploding Diversity of a Unique Class of Compounds
2005 Standout
In Situ Click Chemistry: Enzyme‐Generated Inhibitors of Carbonic Anhydrase II
2004 StandoutNobel
Carbonic Anhydrase Inhibitors: Synthesis of Sulfonamides Incorporating 2, 4, 6–Trisubstituted-Pyridinium-Ethylcarboxamido Moieties Possessing Membrane-Impermeability and in Vivo Selectivity for the Membrane-Bound (CA IV) Versus the Cytosolic (CA I and CA II) Isozymes
2000
Determination of binding selectivities in host-guest complexation by electrospray/quadrupole ion trap mass spectrometry
1998
Identification and Isolation of a Receptor forN-Methyl Alkylammonium Salts: Molecular Amplification in a Pseudo-peptide Dynamic Combinatorial Library
2001
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
2018 StandoutNobel
Steric and Dynamic Parameters Influencing In Situ Cycloadditions to Form Triazole Inhibitors with Crystalline Acetylcholinesterase
2016 StandoutNobel
A Cyclic Hexapeptide Containing L ‐Proline and 6‐Aminopicolinic Acid Subunits Binds Anions in Water
2001
Conformational Preferences of Linear β-Defensins Are Revealed by Ion Mobility-Mass Spectrometry
2010 StandoutNobel
Water as an Active Constituent in Cell Biology
2007 Standout
Oligosaccharide Mimetics Obtained by Novel, Rapid Screening of Carboxylic Acid Encoded Glycopeptide Libraries
1998 StandoutNobel
Direct screening of a dynamic combinatorial library using mass spectrometry
2006
Identification and Isolation of a Receptor for N-Methyl Alkylammonium Salts: Molecular Amplification in a Pseudo-peptide Dynamic Combinatorial Library This work was supported by the Biotechnology and Biological Sciences Research Council (UK), Engineering and Physical Sciences Research Council (UK), Ethyl Corporation (UK), and Fundacion Antorchas and Consejo Nacional de Investigaciones Cientficas y Tecnicas (Argentina).
2001
Cucurbituril-Based Molecular Recognition
2015 Standout
Determination of alkali metal cation selectivities of dibenzo-16-crown-5 lariat ethers with ether pendant groups by using electrospray ionization quadrupole ion trap mass spectrometry
2001
In Situ Click Chemistry: Enzyme‐Generated Inhibitors of Carbonic Anhydrase II
2004 StandoutNobel
Mass Spectrometry
1996
Combinatorial Synthesis of Small Organic Molecules
1996
Correlating Solution Binding and ESI-MS Stabilities by Incorporating Solvation Effects in a Confined Cucurbit[8]uril System
2010
Detection of high molecular weight starburst dendrimers by electrospray ionization mass spectometry
1995
Dynamic Combinatorial Chemistry
2006 Standout
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
Non-Zinc Mediated Inhibition of Carbonic Anhydrases: Coumarins Are a New Class of Suicide Inhibitors
2009
Generation of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein Template
2012 StandoutNobel
Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
2013 StandoutNobel
Investigating Molecular Recognition by Mass Spectrometry: Characterization of Calixarene-Based Self-Assembling Capsule Hosts with Charged Guests
1999
Quantitative determination of noncovalent binding interactions using soft ionization mass spectrometry
2002
Dendrimers—Branching out from curiosities into new technologies
1998 StandoutNobel
Click Chemistry In Situ: Acetylcholinesterase as a Reaction Vessel for the Selective Assembly of a Femtomolar Inhibitor from an Array of Building Blocks
2002 StandoutNobel
About Dendrimers: Structure, Physical Properties, and Applications
1999 Standout
Atmospheric pressure ionization permanent magnet fourier transform ion cyclotron resonance mass spectrometry
2007 StandoutNobel
Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation
2004 StandoutNobel
Identification and Isolation of a Receptor forN-Methyl Alkylammonium Salts: Molecular Amplification in a Pseudo-peptide Dynamic Combinatorial Library
2001
Gas-Phase Conformation of Biological Molecules: Bradykinin
1996
In situclick chemistry: a powerful means for lead discovery
2006 StandoutNobel
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Mass Spectrometry Sampling Under Ambient Conditions with Desorption Electrospray Ionization
2004 StandoutScience
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
2020 StandoutNobel
Analysis of Noncovalent Complexes of DNA and RNA by Mass Spectrometry
2001
In Situ Selection of Lead Compounds by Click Chemistry: Target-Guided Optimization of Acetylcholinesterase Inhibitors
2005 StandoutNobel
Carbonic Anhydrase as a Model for Biophysical and Physical-Organic Studies of Proteins and Protein−Ligand Binding
2008
Ruthenium-Catalyzed Cycloaddition of Alkynes and Organic Azides
2005 StandoutNobel
The “One-Bead-One-Compound” Combinatorial Library Method
1997
External accumulation of ions for enhanced electrospray ionization fourier transform ion cyclotron resonance mass spectrometry
1997
SPOCC: A Resin for Solid-Phase Organic Chemistry and Enzymatic Reactions on Solid Phase
1999 StandoutNobel
Crown Ethers: Sensors for Ions and Molecular Scaffolds for Materials and Biological Models
2004 Standout
Helicates as Versatile Supramolecular Complexes
1997 Standout
Disruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activity
2004 StandoutNobel
Dynamic Combinatorial Mass Spectrometry Leads to Metallo-β-lactamase Inhibitors
2008
Carbonic Anhydrase Activity Modulators: Synthesis of Inhibitors and Activators Incorporating 2-substituted-thiazol-4-yl-methyl Scaffolds
2001
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout
Mass Spectrometry and Protein Analysis
2006 StandoutScience
Works of Ruidan Chen being referenced
Bio‐affinity characterization mass spectrometry
1995
Screening Derivatized Peptide Libraries for Tight Binding Inhibitors to Carbonic Anhydrase II by Electrospray Ionization-Mass Spectrometry
1996
A high performance low magnetic field internal electrospray ionization-fourier transform ion cyclotron resonance mass spectrometer
1996
Using Electrospray Ionization FTICR Mass Spectrometry To Study Competitive Binding of Inhibitors to Carbonic Anhydrase
1995
Direct Charge Number and Molecular Weight Determination of Large Individual Ions by Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
1994
Linear excitation and detection in Fourier transform ion cyclotron resonance mass spectrometry
1994