Citation Impact
Citing Papers
Characterizing and explaining the impact of disease-associated mutations in proteins without known structures or structural homologs
2022 StandoutNobel
Trans-splicing of the C. elegans let-7 primary transcript developmentally regulates let-7 microRNA biogenesis and let-7 family microRNA activity
2019 StandoutNobel
CRISPR–Cas9 Structures and Mechanisms
2017 StandoutNobel
A genome-wide CRISPR-based screen identifies KAT7 as a driver of cellular senescence
2021
Systematic mapping of functional enhancer–promoter connections with CRISPR interference
2016 Science
Transcriptional Regulation by Nrf2
2017 Standout
Critical contribution of 3′ non-seed base pairing to the in vivo function of the evolutionarily conserved let-7a microRNA
2022 StandoutNobel
CRISPR library designer (CLD): software for multispecies design of single guide RNA libraries
2016
Gastric cancer
2016 Standout
Guide-bound structures of an RNA-targeting A-cleaving CRISPR–Cas13a enzyme
2017 StandoutNobel
dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
2022 StandoutNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Genome-scale high-resolution mapping of activating and repressive nucleotides in regulatory regions
2016
Neat1 is a p53-inducible lincRNA essential for transformation suppression
2017
A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic Screens
2019
Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation
2017
The evolving landscape of biomarkers for checkpoint inhibitor immunotherapy
2019 Standout
Ribosome Footprint Profiling of Translation throughout the Genome
2016
Genome-Editing Technologies: Principles and Applications
2016
Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes
2017
The multidimensional mechanisms of long noncoding RNA function
2017 Standout
The emerging role of lncRNAs in cancer
2015 Standout
Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects
2020 Standout
Hallmarks of aging: An expanding universe
2023 Standout
Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection
2018 StandoutNobel
Immunosuppressants in cancer prevention and therapy
2013
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
Effective gene expression prediction from sequence by integrating long-range interactions
2021 StandoutNobel
Long Noncoding RNAs in Cancer Pathways
2016 Standout
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
The Human Transcription Factors
2018 Standout
Deciphering regulatory DNA sequences and noncoding genetic variants using neural network models of massively parallel reporter assays
2019
Application of CRISPR-mediated genome engineering in cancer research
2016
Non-coding driver mutations in human cancer
2021
Long Noncoding RNAs in Cancer: From Function to Translation
2015
Dynamic RNA Modifications in Gene Expression Regulation
2017 Standout
Familial gastric cancer: genetic susceptibility, pathology, and implications for management
2015
A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells
2021
High-Throughput Approaches to Pinpoint Function within the Noncoding Genome
2017
Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation
2018 Standout
CRISPR/Cas9-Based Engineering of the Epigenome
2017
The Role of Tumor Suppressor p53 in the Antioxidant Defense and Metabolism
2014
Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening
2017
GWIPS-viz: development of a ribo-seq genome browser
2013
GUARDIN is a p53-responsive long non-coding RNA that is essential for genomic stability
2018
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
2023 Standout
Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR–Cas9 library
2016
Oxidative Stress in Cancer
2020 Standout
An inducible long noncoding RNA amplifies DNA damage signaling
2016
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
Towards a comprehensive catalogue of validated and target-linked human enhancers
2020
Gastric cancer
2020 Standout
The next generation of CRISPR–Cas technologies and applications
2019
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Interpreting neural networks for biological sequences by learning stochastic masks
2022 StandoutNobel
Reading, writing and erasing mRNA methylation
2019 Standout
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome
2017
CRISPR–Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome
2017
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events
2016
GuideScan software for improved single and paired CRISPR guide RNA design
2017
A Specialized Mechanism of Translation Mediated by FXR1a-Associated MicroRNP in Cellular Quiescence
2016
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma
2018
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
CRISPR/Cas9 for cancer research and therapy
2018
Long Noncoding RNA and Cancer: A New Paradigm
2017 Standout
Systematic discovery of natural CRISPR-Cas12a inhibitors
2018 StandoutScienceNobel
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
The chemistry of Cas9 and its CRISPR colleagues
2017 StandoutNobel
Conditional Recruitment to a DNA-Bound CRISPR–Cas Complex Using a Colocalization-Dependent Protein Switch
2020 StandoutNobel
Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development
2022 StandoutNobel
Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3
2017
Combination therapy in combating cancer
2017 Standout
Revealing a human p53 universe
2018
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
CRISPOR: intuitive guide selection for CRISPR/Cas9 genome editing experiments and screens
2018 Standout
CRISPR-Cas in Streptococcus pyogenes
2019 StandoutNobel
CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks
2020 StandoutNobel
2016
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of Rui Lopes being referenced
p53 induces transcriptional and translational programs to suppress cell proliferation and growth
2013
Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA
2015
E-Cadherin Destabilization Accounts for the Pathogenicity of Missense Mutations in Hereditary Diffuse Gastric Cancer
2012
Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9
2016
Tumour-specific proline vulnerability uncovered by differential ribosome codon reading
2016 Nature