Citation Impact
Citing Papers
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
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TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
2008 StandoutScience
Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease
2010 StandoutScience
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
Sleep Drives Metabolite Clearance from the Adult Brain
2013 StandoutScience
Structure-based inhibitors of amyloid beta core suggest a common interface with tau
2019
Apolipoprotein E and Alzheimer's disease: the influence of apolipoprotein E on amyloid-β and other amyloidogenic proteins
2017
Olig2-Regulated Lineage-Restricted Pathway Controls Replication Competence in Neural Stem Cells and Malignant Glioma
2007
Elucidating Tau function and dysfunction in the era of cryo-EM
2019
Pathogenic implications of iron accumulation in multiple sclerosis
2011
Advances in the Cellular and Molecular Biology of the Beta-Amyloid Protein in Alzheimer 's Disease
2002
Pathological Changes in Dopaminergic Nerve Cells of the Substantia Nigra and Olfactory Bulb in Mice Transgenic for Truncated Human α-Synuclein(1–120): Implications for Lewy Body Disorders
2006
IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
2004 Standout
Human apolipoprotein E4 accelerates β‐amyloid deposition in APPsw transgenic mouse brain
2001
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
pH-Dependent Amyloid and Protofibril Formation by the ABri Peptide of Familial British Dementia
2003
ApoE Promotes the Proteolytic Degradation of Aβ
2008
Substitutions at codon 22 of Alzheimer's A beta peptide induce conformational changes and diverse apoptotic effects in human cerebral endothelial cells
2000
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
2002 StandoutNature
Iron metabolism in the CNS: implications for neurodegenerative diseases
2013
mRNA Is an Endogenous Ligand for Toll-like Receptor 3
2004 StandoutNobel
Variant Alzheimer Disease With Spastic paraparesis: Neuropathological phenotype
2001
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies
2009
Neurodegeneration with brain iron accumulation — Clinical syndromes and neuroimaging
2011
Low-density Lipoprotein Receptor Represents an Apolipoprotein E-independent Pathway of Aβ Uptake and Degradation by Astrocytes
2012
Classification and basic pathology of Alzheimer disease
2009
Atomic structures of amyloid cross-β spines reveal varied steric zippers
2007 StandoutNature
Amyloid structure determination in RELION -3.1
2020
apoE isoform–specific disruption of amyloid β peptide clearance from mouse brain
2008
Neuroferritinopathy: a new inborn error of iron metabolism
2012
βAPP and Furin mRNA Concentrates in Immature Senile Plaques in the Brain of Alzheimer Patients
2002
Variable phenotype of Alzheimer's disease with spastic paraparesis
2001
TAR-DNA Binding Protein 43 in Pick Disease
2008
Clinical, Pathological, and Biochemical Spectrum of Alzheimer Disease Associated With PS-1 Mutations
2004
Oxidative stress and cell death in cells expressing L-ferritin variants causing neuroferritinopathy
2009
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
2002 StandoutNature
Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage
2010
Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus
2018
A New Human Hereditary Amyloidosis: The Result of a Stop-Codon Mutation in the Apolipoprotein AII Gene
2001
Chemical Typing of Amyloid Protein Contained in Formalin-Fixed Paraffin-Embedded Biopsy Specimens
2001
Animal models of human amyloidoses: Are transgenic mice worth the time and trouble?
2009
ApoE and Clusterin Cooperatively Suppress Aβ Levels and Deposition
2004
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
2015 Standout
Amyloid fibrillogenesis: themes and variations
2000
In vivo reprogramming of adult pancreatic exocrine cells to β-cells
2008 StandoutNature
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
2010
Two to Tango: Regulation of Mammalian Iron Metabolism
2010 Standout
Anti-fibrogenic function of angiotensin II type 2 receptor in CCl4-induced liver fibrosis
2006
Metallobiology of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity
2013
Protein folding and misfolding
2003 StandoutNature
Genetics and Pathophysiology of Neurodegeneration with Brain Iron Accumulation (NBIA)
2013
Progressive Brain Iron Accumulation in Neuroferritinopathy Measured by the Thalamic T2* Relaxation Rate
2012
Four structural risk factors identify most fibril-forming kappa light chains
2000
The Structure of Amyloid Fibrils by Electron Microscopy and X-Ray Diffraction
1997
Malignant Gliomas in Adults
2008 Standout
Inhibition of NF-κB Activation by Arsenite through Reaction with a Critical Cysteine in the Activation Loop of IκB Kinase
2000 StandoutNobel
Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis
2004 Standout
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
2013 StandoutNobel
The Role of Apolipoprotein E in Alzheimer's Disease
2009
Mechanism of Cerebral β-Amyloid Angiopathy: Murine and Cellular Models
2006
Current Concepts and Controversies in Neurodegeneration with Brain Iron Accumulation
2012
Review: Amyloidogenesis—Unquestioned Answers and Unanswered Questions
2000
The role of iron in brain ageing and neurodegenerative disorders
2014 Standout
The Amyloid State of Proteins in Human Diseases
2012 Standout
Developmental iron uptake and axonal transport in the retina of the rat
2011
Familial Danish Dementia
2005
Environmental Enrichment Reduces Aβ Levels and Amyloid Deposition in Transgenic Mice
2005 Standout
Non-fibrillar oligomeric species of the amyloid ABri peptide, implicated in familial British dementia, are more potent at inducing apoptotic cell death than protofibrils or mature fibrils11Edited by J. Karn
2001
Aged vervet monkeys developing transthyretin amyloidosis with the human disease-causing Ile122 allele: a valid pathological model of the human disease
2011
Glutaminyl cyclase inhibition attenuates pyroglutamate Aβ and Alzheimer's disease–like pathology
2008
Systematic Mutagenesis of α-Synuclein Reveals Distinct Sequence Requirements for Physiological and Pathological Activities
2012 StandoutNobel
Clearance of Alzheimer’s amyloid-β1-40 peptide from brain by LDL receptor–related protein-1 at the blood-brain barrier
2000
Benzoxazoles as Transthyretin Amyloid Fibril Inhibitors: Synthesis, Evaluation, and Mechanism of Action
2003
Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
2012 Standout
Iron, brain ageing and neurodegenerative disorders
2004
Alzheimer's Disease
2004 Standout
TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth
2006 Standout
Differential Diagnosis of Glomerular Disease: A Systematic and Inclusive Approach
2013 Standout
Domain Stability in Immunoglobulin Light Chain Deposition Disorders
1997
The role of microglia in amyloid clearance from the AD brain
2010
The Evolution of Gene Expression, Structure and Function of Transthyretin
1997
Clinical features and natural history of neuroferritinopathy caused by the FTL1 460InsA mutation
2006
Hydroxylated Polychlorinated Biphenyls Selectively Bind Transthyretin in Blood and Inhibit Amyloidogenesis: Rationalizing Rodent PCB Toxicity
2004
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
Light chain deposition disease: novel biological insights and treatment advances
2012
Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia
1999
Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
2015 Standout
Molecular Mechanisms of Amyloidosis
2003 Standout
Tau pathology and neurodegeneration
2013
Cerebral amyloid angiopathy plays a direct role in the pathogenesis of Alzheimer’s disease
2004
Brain iron metabolism: Neurobiology and neurochemistry
2007
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Substitutions at Codon 22 of Alzheimer's Aβ Peptide Induce Diverse Conformational Changes and Apoptotic Effects in Human Cerebral Endothelial Cells
2000
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
2015 StandoutNobel
Diagnosis and Management of the Cardiac Amyloidoses
2005
Transthyretin-derived senile systemic amyloidosis: clinicopathologic and structural considerations
2003
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
Regulation of glycogen synthase kinase 3 in human platelets: a possible role in platelet function?1
2003
Transmissibility of systemic amyloidosis by a prion-like mechanism
2002
Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance
2011
A Century of Alzheimer's Disease
2006 StandoutScience
Common Pathological Processes and Transcriptional Pathways in Alzheimer's Disease and Type 2 Diabetes
2009
Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Aβ toxicity
2008
Structure-Based Design of Functional Amyloid Materials
2014 StandoutNobel
ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions
2013
Copper and Iron Disorders of the Brain
2007
Prion infection impairs the cellular response to oxidative stress
2000
The tropism of organ involvement in primary systemic amyloidosis: contributions of Ig VL germ line gene use and clonal plasma cell burden
2001
Spontaneous Hemorrhagic Stroke in a Mouse Model of Cerebral Amyloid Angiopathy
2001
Fluorescent Sensors for Measuring Metal Ions in Living Systems
2014 Standout
The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
2011 Standout
Amyloid β40/42 clearance across the blood-brain barrier following intra-ventricular injections in wild-type, apoE knock-out and human apoE3 or E4 expressing transgenic mice
2001
Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease
2010
Iron Toxicity in Diseases of Aging: Alzheimer's Disease, Parkinson's Disease and Atherosclerosis
2009
Nocardia species: host-parasite relationships
1994 Standout
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Casting Metal Nanowires Within Discrete Self-Assembled Peptide Nanotubes
2003 StandoutScience
Designed amyloid fibers as materials for selective carbon dioxide capture
2013 StandoutNobel
Proteases and Proteolysis in Alzheimer Disease: A Multifactorial View on the Disease Process
2010
Epithelial-to-Mesenchymal Transition Generates Proliferative Human Islet Precursor Cells
2004 Science
Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis
2003 StandoutScience
Alterations in NF-κB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-κB
1998
The Development of Amyloid β Protein Deposits in the Aged Brain
2006
A possible role for π‐stacking in the self‐assembly of amyloid fibrils
2002
Immunoglobulin light chains, glycosaminoglycans, and amyloid
2000
Free Radicals in the Physiological Control of Cell Function
2002 Standout
MRI Findings in Neuroferritinopathy
2011
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease
2001
Works of Rubén Vidal being referenced
Familial cerebral amyloid angiopathy related to stroke and dementia.
2001
Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations
2008
Endogenous Proteolytic Cleavage of Normal and Disease-Associated Isoforms of the Human Prion Protein in Neural and Non-Neural Tissues
1998
Intracellular Ferritin Accumulation in Neural and Extraneural Tissue Characterizes a Neurodegenerative Disease Associated with a Mutation in theFerritin Light PolypeptideGene
2004
Apolipoprotein E and Amyloidogenesis
2007
Immunochemical Microanalysis of Amyloid Proteins in Fine-Needle Aspirates of Abdominal Fat
1999
Somatic Mutations of the L12a Gene in V-κ1 Light Chain Deposition Disease
1999
Expression of a Mutant Form of the Ferritin Light Chain Gene Induces Neurodegeneration and Iron Overload in Transgenic Mice
2008
A Newly Formed Amyloidogenic Fragment due to a Stop Codon Mutation Causes Familial British Dementia
2000
Abnormal iron metabolism and oxidative stress in mice expressing a mutant form of the ferritin light polypeptide gene
2009
Clinical phenotype and neuroimaging findings in a French family with hereditary ferritinopathy (FTL498‐499InsTC)
2009
Senile dementia associated with amyloid β protein angiopathy and tau perivascular pathology but not neuritic plaques in patients homozygous for the APOE-ε4 allele
2000
Kappa light chain-associated Fanconi's syndrome: molecular analysis of monoclonal immunoglobulin light chains from patients with and without intracellular crystals
1999
A stop-codon mutation in the BRI gene associated with familial British dementia
1999 Nature
A mutant light-chain ferritin that causes neurodegeneration has enhanced propensity toward oxidative damage
2012
Early‐onset Dementia with Lewy Bodies
2004
Chromosome 13 dementia syndromes as models of neurodegeneration
2001
Sequence, genomic structure and tissue expression of Human BRI 3 , a member of the BRI gene family
2001
Familial Danish Dementia: A Novel Form of Cerebral Amyloidosis Associated with Deposition of Both Amyloid-Dan and Amyloid-Beta
2002
Immunolocalization of the Oligodendrocyte Transcription Factor 1 (Olig1) in Brain Tumors
2004
Cerebral Amyloid Angiopathy and Parenchymal Amyloid Deposition in Transgenic Mice Expressing the Danish Mutant Form of Human BRI2
2008
Amyloid and Nonfibrillar Deposits in Mice Transgenic for Wild-Type Human Transthyretin: A Possible Model for Senile Systemic Amyloidosis
2001
Iron-mediated Aggregation and a Localized Structural Change Characterize Ferritin from a Mutant Light Chain Polypeptide That Causes Neurodegeneration
2008
Abnormal iron metabolism in fibroblasts from a patient with the neurodegenerative disease hereditary ferritinopathy
2010
Structures of filaments from Pick’s disease reveal a novel tau protein fold
2018 Nature
Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold
2018
pH‐dependent fibrillogenesis of a VκIII Bence Jones protein
1999
Alzheimer's presenilin 1 gene expression in platelets and megakaryocytes
1996
Unraveling of the E-helices and Disruption of 4-Fold Pores Are Associated with Iron Mishandling in a Mutant Ferritin Causing Neurodegeneration
2009
Systemic Amyloid Deposits in Familial British Dementia
2001
Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules
2019 Nature
Regional Distribution of Amyloid-Bri Deposition and Its Association with Neurofibrillary Degeneration in Familial British Dementia
2001
Accumulation of oxidative DNA damage in brain mitochondria in mouse model of hereditary ferritinopathy
2010
Hereditary ferritinopathy
2003
Meningocerebrovascular amyloidosis associated with a novel transthyretin mis-sense mutation at codon 18 (TTRD 18G)
1996
A decamer duplication in the 3′ region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred
2000
On the role of AP2 in epithelial-specific gene expression.
1993
Renal and cardiac manifestations of B-cell dyscrasias with nonamyloidotic monoclonal light chain and light and heavy chain deposition diseases.
1998
Clinicopathologic features of frontotemporal dementia with Progranulin sequence variation
2007
Light chain cardiomyopathy. Structural analysis of the light chain tissue deposits.
1996
Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid β peptides
2000
Alveolar proteinosis and nocardiosis: a patient treated by bronchopulmonary lavage
1989
Amino-Terminally Truncated Aβ Peptide Species Are the Main Component of Cotton Wool Plaques
2005