Citation Impact
Citing Papers
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
2008 Standout
Silencing of Epidermal Growth Factor Receptor Suppresses Hypoxia-Inducible Factor-2–Driven VHL −/− Renal Cancer
2005
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
2009 StandoutScience
Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells
2009 Science
Differentiation Stage-Specific Requirement in Hypoxia-Inducible Factor-1α–Regulated Glycolytic Pathway during Murine B Cell Development in Bone Marrow
2009 StandoutNobel
Treatment of kidney cancer
2009 StandoutNobel
A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions
2020
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
Hypoxia-Inducible Factor Linked to Differential Kidney Cancer Risk Seen with Type 2A and Type 2B VHL Mutations
2007 StandoutNobel
Imaging beyond the proteome
2012 StandoutNobel
Targeting hypoxia in cancer therapy
2011 Standout
IDH1andIDH2Mutations in Gliomas
2009 Standout
The transcription factor HIF-1α plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis
2007
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
2008 StandoutNature
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
AKT/PKB Signaling: Navigating Downstream
2007 Standout
HIF-Dependent Antitumorigenic Effect of Antioxidants In Vivo
2007 StandoutNobel
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
2007 Standout
Evaluation of a cell penetrating prenylated peptide lacking an intrinsic fluorophore via in situ click reaction
2011
RAS oncogenes: weaving a tumorigenic web
2011
Cancer Cell Metabolism: Warburg and Beyond
2008 Standout
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Pyruvate Dehydrogenase Complex Activity Controls Metabolic and Malignant Phenotype in Cancer Cells
2008
Malignant astrocytic glioma: genetics, biology, and paths to treatment
2007 Standout
Otto Warburg's contributions to current concepts of cancer metabolism
2011 Standout
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
Causes and Consequences of Increased Glucose Metabolism of Cancers
2008
Wasting in Cancer
1999
Ras history
2010
Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?
2010
Hypoxia signalling controls metabolic demand
2007
Orally administered FTS (salirasib) inhibits human pancreatic tumor growth in nude mice
2007
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
Secreted Glioblastoma Nanovesicles Contain Intracellular Signaling Proteins and Active Ras Incorporated in a Farnesylation-dependent Manner
2016
Shedding light on the cell biology of extracellular vesicles
2018 Standout
Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells
2006
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Regulation of cancer cell metabolism
2011 Standout
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs
2014
Self-consumption: the interplay of autophagy and apoptosis
2014 Standout
Malignant Gliomas in Adults
2008 Standout
Ras transformation requires metabolic control by 6-phosphofructo-2-kinase
2006
Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment
2016 StandoutNobel
Inflammation and cancer: back to Virchow?
2001 Standout
Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer
2010
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Pancreatic Cancer
2010 Standout
The von Hippel–Lindau protein, HIF hydroxylation, and oxygen sensing
2005 StandoutNobel
ATP citrate lyase inhibition can suppress tumor cell growth
2005
Mitochondrial TCA cycle metabolites control physiology and disease
2020 Standout
eRNAs Promote Transcription by Establishing Chromatin Accessibility at Defined Genomic Loci
2013
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
2008 Standout
Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6
2008 Standout
Enhancers as non-coding RNA transcription units: recent insights and future perspectives
2016
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Ras-dependent carbon metabolism and transformation in mouse fibroblasts
2006
Oxidative Dimerization of PHD2 is Responsible for its Inactivation and Contributes to Metabolic Reprogramming via HIF-1α Activation
2016
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
2007 Standout
Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements
2005
Exploring Protein Lipidation with Chemical Biology
2011
Metabolic reprogramming by HIF-1 promotes the survival of bone marrow–derived angiogenic cells in ischemic tissue
2011 StandoutNobel
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Kinase requirements in human cells: III. Altered kinase requirements inVHL−/− cancer cells detected in a pilot synthetic lethal screen
2008 StandoutNobel
Hypoxia-Inducible Factor 1 and Dysregulated c-Myc Cooperatively Induce Vascular Endothelial Growth Factor and Metabolic Switches Hexokinase 2 and Pyruvate Dehydrogenase Kinase 1
2007 StandoutNobel
Click-Chemistry Based High Throughput Screening Platform for Modulators of Ras Palmitoylation
2017 StandoutNobel
Ras inhibition enhances autophagy, which partially protects cells from death
2013
Metabolic reprogramming and cancer progression
2020 StandoutScience
An Adenosine-Mediated Signaling Pathway Suppresses Prenylation of the GTPase Rap1B and Promotes Cell Scattering
2013
Cancer Genome Landscapes
2013 StandoutScience
The von Hippel-Lindau Tumor Suppressor Protein and Clear Cell Renal Carcinoma
2007 StandoutNobel
KRAS Mutant Pancreatic Cancer: No Lone Path to an Effective Treatment
2016
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Biology of Cachexia
1997
Works of Roy Blum being referenced
Ras Inhibition in Glioblastoma Down-regulates Hypoxia-Inducible Factor-1α, Causing Glycolysis Shutdown and Cell Death
2005
Xist RNA antagonizes the SWI/SNF chromatin remodeler BRG1 on the inactive X chromosome
2019
E2F1 identified by promoter and biochemical analysis as a central target of glioblastoma cell‐cycle arrest in response to ras inhibition
2006
Ras inhibition results in growth arrest and death of androgen-dependent and androgen-independent prostate cancer cells
2006
Genome-wide identification of enhancers in skeletal muscle: the role of MyoD1
2012
Tailoring Ras-pathway—Inhibitor combinations for cancer therapy
2005
A Role for H3K4 Monomethylation in Gene Repression and Partitioning of Chromatin Readers
2014
Inhibitors of Chronically Active Ras: Potential for Treatment of Human Malignancies
2008
Genome-wide remodeling of the epigenetic landscape during myogenic differentiation
2011
Limited impact of total parenteral nutrition on nutritional status during treatment for small cell lung cancer
1986
Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death.
2005