Standout Papers

Modulation of NF‐κB‐dependent transcription and cell survi... 1991 2026 2002 2014 2.2k
  1. Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase (2004)
    Fan Yeung, Michael D. Keller et al. The EMBO Journal
  2. hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase (2001)
    Homayoun Vaziri, Scott Dessain et al. Cell
  3. Phylogenetic Classification of Prokaryotic and Eukaryotic Sir2-like Proteins (2000)
    Roy A. Frye Biochemical and Biophysical Research Communications
  4. Characterization of Five Human cDNAs with Homology to the Yeast SIR2 Gene: Sir2-like Proteins (Sirtuins) Metabolize NAD and May Have Protein ADP-Ribosyltransferase Activity (1999)
    Roy A. Frye Biochemical and Biophysical Research Communications
  5. axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase. (1991)
    John P. O’Bryan, Roy A. Frye et al. Molecular and Cellular Biology

Immediate Impact

3 by Nobel laureates 52 from Science/Nature 181 standout
Sub-graph 1 of 7

Citing Papers

Control of eukaryotic phosphate homeostasis by inositol polyphosphate sensor domains
2016 StandoutScience
NAD + in aging, metabolism, and neurodegeneration
2015 StandoutScience
87 intermediate papers

Works of Roy A. Frye being referenced

The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide–dependent deacetylase
2002
hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase
2001 Standout
and 9 more

Author Peers

Author Last Decade Papers Cites
Roy A. Frye 4709 4937 1753 2496 27 10.3k
Katrin F. Chua 6683 4725 1660 2683 41 11.5k
David B. Lombard 6502 4671 1556 3615 80 12.4k
Haim Cohen 5533 6322 1241 4150 73 12.2k
Jill C. Milne 4632 4464 546 4382 29 10.1k
Bjoern Schwer 3315 3051 775 2162 33 6.4k
Joseph T. Rodgers 5215 3369 625 4451 29 9.6k
Brian J. North 3072 2610 887 1384 53 6.2k
Hwei-Ling Cheng 2924 2390 740 1364 22 5.4k
Delin Chen 5269 1896 2285 951 36 7.5k
Jay H. Chung 4967 1273 1061 1492 71 7.5k

All Works

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Rankless by CCL
2026