Standout Papers
Citation Impact
Citing Papers
Effective expansion of alloantigen-specific Foxp3 + CD25 + CD4 + regulatory T cells by dendritic cells during the mixed leukocyte reaction
2006 StandoutNobel
CD4+ Tregs and immune control
2004 StandoutNobel
PDL1 Is Required for Peripheral Transplantation Tolerance and Protection from Chronic Allograft Rejection
2007
A Combination of Chemoimmunotherapies Can Efficiently Break Self-Tolerance and Induce Antitumor Immunity in a Tolerogenic Murine Tumor Model
2007 StandoutNobel
Enhanced efficacy of DNA vaccination against Her‐2/neu tumor antigen by genetic adjuvants
2004
CTLA4Ig: Bridging the Basic Immunology with Clinical Application
2006
Granulocyte‐macrophage–colony‐stimulating factor added to a multipeptide vaccine for resected Stage II melanoma
2002
New insights into T cell biology and T cell‐directed therapy for autoimmunity, inflammation, and immunosuppression
2010
Mechanisms of Thrombus Formation
2008 Standout
Toxoplasmosis
2004 Standout
Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade
2003
The role of the graft in establishing tolerance
2002
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Recruitment and expansion of dendritic cells in vivo potentiate the immunogenicity of plasmid DNA vaccines
2004
Regulatory T Cells
2000 StandoutNobel
Co-delivery of plasmid-encoded cytokines modulates the immune response to a DNA vaccine delivered by in vivo electroporation
2006
CD40 Ligation Releases Immature Dendritic Cells from the Control of Regulatory CD4+CD25+ T Cells
2003
Inflammation and insulin resistance
2006 Standout
Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
2005 StandoutNobel
SIX-YEAR CLINICAL EFFECT OF DONOR BONE MARROW INFUSIONS IN RENAL TRANSPLANT PATIENTS1
2001
Foxp3+CD25+CD4+ natural regulatory T cells in dominant self‐tolerance and autoimmune disease
2006 StandoutNobel
T cell–directed therapies: lessons learned and future prospects
2006
The KRN mouse model of inflammatory arthritis
2003
CD154 Blockade for Induction of Mixed Chimerism and Prolonged Renal Allograft Survival in Nonhuman Primates
2004
CD40L stabilizes arterial thrombi by a β3 integrin–dependent mechanism
2002
Induction of transplantation tolerance—the potential of regulatory T cells
2005
The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
2006 Standout
Prospects for CD40-directed experimental therapy of human cancer
2002
Type 1 diabetes
2013 Standout
Regulatory T cells in transplantation tolerance
2003 StandoutNobel
LONG-TERM OUTCOME AND ALLOANTIBODY PRODUCTION IN A NON-MYELOABLATIVE REGIMEN FOR INDUCTION OF RENAL ALLOGRAFT TOLERANCE1
1999
Strategies to Improve Long-Term Outcomes after Renal Transplantation
2002 Standout
Clinical Trials of Transplant Tolerance: Slow But Steady Progress
2003
The role of regulatory T cells in controlling immunologic self-tolerance
2003 StandoutNobel
Regulatory T cells under scrutiny
2003
CD8+ T CELLS CONTRIBUTE TO THE DEVELOPMENT OF TRANSPLANT ARTERIOSCLEROSIS DESPITE CD154 BLOCKADE1
2000
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Targeting Immunosupportive Cancer Therapies: Accentuate the Positive, Eliminate the Negative
2007 StandoutNobel
The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells
2008 StandoutNobel
Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance
1999
The Immunobiology of Inductive Anti-CD40L Therapy in Transplantation: Allograft Acceptance is Not Dependent Upon the Deletion of Graft-Reactive T Cells
2002
Immunosuppressive Drugs for Kidney Transplantation
2004 Standout
What's in the Pipeline? New Immunosuppressive Drugs in Transplantation
2002
A large focus of naturally acquired Plasmodium knowlesi infections in human beings
2004 Standout
Depletion of CD8 Memory T Cells for Induction of Tolerance of a Previously Transplanted Kidney Allograft
2007
HLA-Mismatched Renal Transplantation without Maintenance Immunosuppression
2008 Standout
CD40L Blockade Prevents Autoimmune Diabetes by Induction of Bitypic NK/DC Regulatory Cells
2002
Dominant tolerance: activation thresholds for peripheral generation of regulatory T cells
2005
Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance
2002 StandoutNobel
Tolerance to vascularized organ allografts in large-animal models
1999
CD70 Signaling Is Critical for CD28-Independent CD8+ T Cell-Mediated Alloimmune Responses In Vivo
2005
Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway
2008 StandoutNobel
CD40 Signaling and Plaque Instability
2001
Naturally Arising CD4+Regulatory T Cells for Immunologic Self -Tolerance and Negative Control of Immune Responses
2003 StandoutNobel
DNA-Encoded Fetal Liver Tyrosine Kinase 3 Ligand and Granulocyte Macrophage-Colony-Stimulating Factor Increase Dendritic Cell Recruitment to the Inoculation Site and Enhance Antigen-Specific CD4+ T Cell Responses Induced by DNA Vaccination of Outbred Animals
2002
CD40-CD40 Ligand-Independent Activation of CD8+ T Cells Can Trigger Allograft Rejection
2000
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Critical Role of OX40 in CD28 and CD154-Independent Rejection
2004
Targeting Signal 1 Through CD45RB Synergizes with CD40 Ligand Blockade and Promotes Long Term Engraftment and Tolerance in Stringent Transplant Models
2001
CD40-CD40 ligand
2000
Cutting Edge: Anti-CD154 Therapeutic Antibodies Induce Infectious Transplantation Tolerance
2000
Cd4+Cd25+ Immune Regulatory Cells Are Required for Induction of Tolerance to Alloantigen via Costimulatory Blockade
2001
Dendritic cells with TGF-β1 differentiate naïve CD4+CD25−T cells into islet-protective Foxp3+regulatory T cells
2007 StandoutNobel
Advancements in DNA vaccine vectors, non-mechanical delivery methods, and molecular adjuvants to increase immunogenicity
2017
Vaccination with mRNAs encoding tumor-associated antigens and granulocyte-macrophage colony-stimulating factor efficiently primes CTL responses, but is insufficient to overcome tolerance to a model tumor/self antigen
2005
PD-L1/B7H-1 Inhibits the Effector Phase of Tumor Rejection by T Cell Receptor (TCR) Transgenic CD8+ T Cells
2004 StandoutNobel
The role of the graft in establishing tolerance
2002
A Simple Detection Method for Low-Affinity Membrane Protein Interactions by Baculoviral Display
2008 StandoutNobel
Recruitment and expansion of dendritic cells in vivo potentiate the immunogenicity of plasmid DNA vaccines
2004
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
A subset of dendritic cells induces CD4+ T cells to produce IFN-γ by an IL-12–independent but CD70-dependent mechanism in vivo
2007 StandoutNobel
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
The Linkage of Innate to Adaptive Immunity via Maturing Dendritic Cells In Vivo Requires CD40 Ligation in Addition to Antigen Presentation and CD80/86 Costimulation
2004 StandoutNobel
Direct Expansion of Functional CD25+ CD4+ Regulatory T Cells by Antigen-processing Dendritic Cells
2003 StandoutNobel
CD4+ Tregs and immune control
2004 StandoutNobel
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
CD28 disruption exacerbates inflammation in Tgf-β1-/- mice: in vivo suppression by CD4+CD25+ regulatory T cells independent of autocrine TGF-β1
2004 StandoutNobel
Glycolipid α-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice
2006 StandoutNobel
Interleukin-10 and the Interleukin-10 Receptor
2001 Standout
Local Transgenic Expression of Granulocyte Macrophage-Colony Stimulating Factor Initiates Autoimmunity
2001
Alloantigen–induced specific immunological unresponsiveness
2001
The role of peripheral T–cell deletion in transplantation tolerance
2001
Costimulation Blockade of Both Inducible Costimulator and CD40 Ligand Induces Dominant Tolerance to Islet Allografts and Prevents Spontaneous Autoimmune Diabetes in the NOD Mouse
2006
The CD40/CD154 receptor/ligand dyadRID="†"ID="†" Review
2001
Ionizing Radiation Selectively Reduces Skin Regulatory T Cells and Alters Immune Function
2014 StandoutNobel
Functional deficiencies of granulocyte-macrophage colony stimulating factor and interleukin-3 contribute to insulitis and destruction of β cells
2007 StandoutNobel
Protection of Rhesus Macaques against LethalPlasmodium knowlesiMalaria by a Heterologous DNA Priming and Poxvirus Boosting Immunization Regimen
2002
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
CD4+CD25+Foxp3+ T Cells and CD4+CD25−Foxp3+ T Cells in Aged Mice
2006 StandoutNobel
CD4 T Cell-Mediated Alloresistance to Fully MHC-Mismatched Allogeneic Bone Marrow Engraftment Is Dependent on CD40-CD40 Ligand Interactions, and Lasting T Cell Tolerance Is Induced by Bone Marrow Transplantation with Initial Blockade of this Pathway
2001
Antigen-bearing immature dendritic cells induce peptide-specific CD8+ regulatory T cells in vivo in humans
2002 StandoutNobel
Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8 + T cells
2010 StandoutNobel
TheMIC3Gene ofToxoplasma gondiiIs a Novel Potent Vaccine Candidate against Toxoplasmosis
2003
The role of cytokine DNAs as vaccine adjuvants for optimizing cellular immune responses
2004
1α,25-Dihydroxyvitamin D3 Inhibits Differentiation, Maturation, Activation, and Survival of Dendritic Cells Leading to Impaired Alloreactive T Cell Activation
2000
CD40/CD154 Interactions at the Interface of Tolerance and Immunity
2004
Contrasting Roles of IL-2 and IL-15 in the Life and Death of Lymphocytes
2001
Analysis of the Underlying Cellular Mechanisms of Anti-CD154-Induced Graft Tolerance: The Interplay of Clonal Anergy and Immune Regulation
2005 StandoutNobel
Regulatory T Cells Induced by 1α,25-Dihydroxyvitamin D3 and Mycophenolate Mofetil Treatment Mediate Transplantation Tolerance
2001
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Mamu-I: A Novel Primate MHC Class IB-Related Locus with Unusually Low Variability
2000
Potent CD4+ T Cell Responses Elicited by a Bicistronic HIV-1 DNA Vaccine Expressing gp120 and GM-CSF
2002
B7 Expression on T Cells Down-Regulates Immune Responses through CTLA-4 Ligation via R-T Interactions
2004 StandoutNobel
Characterization of Hepatitis C Virus Core-Specific Immune Responses Primed in Rhesus Macaques by a Nonclassical ISCOM Vaccine
2001 StandoutNobel
Works of Roxanne E. Baumgartner being referenced
TREATMENT WITH THE HUMANIZED CD154-SPECIFIC MONOCLONAL ANTIBODY, hu5C8, PREVENTS ACUTE REJECTION OF PRIMARY SKIN ALLOGRAFTS IN NONHUMAN PRIMATES1
2001
Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates
1999 Standout
COADMINISTRATION OF EITHER CYCLOSPORINE OR STEROIDS WITH HUMANIZED MONOCLONAL ANTIBODIES AGAINST CD80 AND CD86 SUCCESSFULLY PROLONG ALLOGRAFT SURVIVAL AFTER LIFE SUPPORTING RENAL TRANSPLANTATION IN CYNOMOLGUS MONKEYS1
2001
Plasmid Vaccine Expressing Granulocyte-Macrophage Colony-Stimulating Factor Attracts Infiltrates Including Immature Dendritic Cells into Injected Muscles
2000