Citation Impact
Citing Papers
Proton Binding to Proteins: p K a Calculations with Explicit and Implicit Solvent Models
2004
Confirmation of intersubunit connectivity and topology of designed protein complexes by native MS
2018 StandoutNobel
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59
2012 StandoutNobel
MutL traps MutS at a DNA mismatch
2015 StandoutNobel
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors
2022 StandoutNobel
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
Protein stability promotes evolvability
2006 StandoutNobel
Mechanisms in Eukaryotic Mismatch Repair
2006 StandoutNobel
Sequence complexity of disordered protein
2000
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
Unravelling biological macromolecules with cryo-electron microscopy
2016 Nature
Dynamic personalities of proteins
2007 StandoutNature
Constant pH molecular dynamics in generalized Born implicit solvent
2004
The β Sliding Clamp Binds to Multiple Sites within MutL and MutS
2006 StandoutNobel
Protonate3D: Assignment of ionization states and hydrogen coordinates to macromolecular structures
2008
Modeling electrostatic effects in proteins
2006 StandoutNobel
Biomolecular simulations at constant pH
2005
Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations
2006
A buried lysine that titrates with a normal pKa: Role of conformational flexibility at the protein–water interface as a determinant of pKavalues
2008
Theoretical investigation of the behavior of titratable groups in proteins
2006
Natural Selection for Kinetic Stability Is a Likely Origin of Correlations between Mutational Effects on Protein Energetics and Frequencies of Amino Acid Occurrences in Sequence Alignments
2006
Target preference of Type III-A CRISPR-Cas complexes at the transcription bubble
2019 StandoutNobel
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
Factors influencing the energetics of electron and proton transfers in proteins. What can be learned from calculations
2006
The MutSα-Proliferating Cell Nuclear Antigen Interaction in Human DNA Mismatch Repair
2008 StandoutNobel
Hydrolytic function of Exo1 in mammalian mismatch repair
2014 StandoutNobel
pK values of the ionizable groups of proteins
2006
Evidence that processing of ribonucleotides in DNA by topoisomerase 1 is leading-strand specific
2015
Simulating electrostatic energies in proteins: Perspectives and some recent studies of pKas, redox, and other crucial functional properties
2011 StandoutNobel
Competitive processivity-clamp usage by DNA polymerases during DNA replication and repair
2003
Folding funnels, binding funnels, and protein function
1999
The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases
2006 StandoutNobel
Very fast empirical prediction and rationalization of protein pKa values
2005 Standout
H++ 3.0: automating pK prediction and the preparation of biomolecular structures for atomistic molecular modeling and simulations
2012
Polypeptide chain collapse and protein folding
2012
Molecular Basis of the Light-driven Switching of the Photochromic Fluorescent Protein Padron
2010 StandoutNobel
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
MCCE2: Improving protein pKa calculations with extensive side chain rotamer sampling
2009
Proton Binding to Proteins: A Free-Energy Component Analysis Using a Dielectric Continuum Model
2005
Survey of the year 2003 commercial optical biosensor literature
2004
Principles and Concepts of DNA Replication in Bacteria, Archaea, and Eukarya
2013
A computational approach for predicting off-target toxicity of antiviral ribonucleoside analogues to mitochondrial RNA polymerase
2018 StandoutNobel
X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution
2007
Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation
2020 StandoutNobel
Relation Between Protein Stability, Evolution and Structure, as Probed by Carboxylic Acid Mutations
2004
Chemically accurate protein structures: Validation of protein NMR structures by comparison of measured and predicted pK a values
2006
AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility
2009 Standout
High Apparent Dielectric Constant Inside a Protein Reflects Structural Reorganization Coupled to the Ionization of an Internal Asp
2006
Are Acidic and Basic Groups in Buried Proteins Predicted to be Ionized?
2005
Insights into the Replisome from the Structure of a Ternary Complex of the DNA Polymerase III α-Subunit
2008 StandoutNobel
Acidic range titration of HEWL using a constant‐pH molecular dynamics method
2008
Analysis of Ribonucleotide Removal from DNA by Human Nucleotide Excision Repair
2015 StandoutNobel
Quantitative fluorescence labeling of aldehyde-tagged proteins for single-molecule imaging
2012
Benchmarking pKa prediction
2006
On the importance of being zwitterionic: enzymatic catalysis of decarboxylation and deprotonation of cationic carbon
2004
Involvement of the β Clamp in Methyl-directed Mismatch Repair in Vitro
2009 StandoutNobel
Toward high-resolution prediction and design of transmembrane helical protein structures
2007 StandoutNobel
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
2015 StandoutNobel
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
2010 StandoutNobel
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
Quantitative exploration of the molecular origin of the activation of GTPase
2013 StandoutNobel
AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements
2007 StandoutNobel
Supramolecular Coordination: Self-Assembly of Finite Two- and Three-Dimensional Ensembles
2011 Standout
Electrostatics and dynamics of proteins
2003
Predicting pKa
2009
CELLULAR DNA REPLICASES: Components and Dynamics at the Replication Fork
2005
PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKaPredictions
2011 Standout
Eukaryotic DNA Replication Fork
2017
A Bipartite Polymerase–Processivity Factor Interaction: Only the Internal β Binding Site of the α Subunit is Required for Processive Replication by the DNA Polymerase III Holoenzyme
2005
Electrostatic basis for the unidirectionality of the primary proton transfer in cytochrome c oxidase
2008 StandoutNobel
Electric Fields at the Active Site of an Enzyme: Direct Comparison of Experiment with Theory
2006 Science
Realistic simulation of the activation of voltage-gated ion channels
2012 StandoutNobel
A Pictet-Spengler ligation for protein chemical modification
2012 StandoutNobel
Prediction and Rationalization of Protein pKa Values Using QM and QM/MM Methods
2005
Progress in Ab Initio QM/MM Free-Energy Simulations of Electrostatic Energies in Proteins: Accelerated QM/MM Studies of pKa, Redox Reactions and Solvation Free Energies
2008 StandoutNobel
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Electrostatic Environment of Hemes in Proteins: pKas of Hydroxyl Ligands
2006
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Realistic simulations of the coupling between the protomotive force and the mechanical rotation of the F 0 -ATPase
2012 StandoutNobel
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
On the Use of Different Dielectric Constants for Computing Individual and Pairwise Terms in Poisson−Boltzmann Studies of Protein Ionization Equilibrium
2005
Molecular Recognition and Docking Algorithms
2003
Accurate, conformation-dependent predictions of solvent effects on protein ionization constants
2007
Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
2013 StandoutNobel
Quantum Mechanical Continuum Solvation Models
2005 Standout
Benchmarking pKa Prediction Methods for Residues in Proteins
2008
Simulating the electrostatic guidance of the vectorial translocations in hexameric helicases and translocases
2009 StandoutNobel
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
On the energetics of translocon-assisted insertion of charged transmembrane helices into membranes
2010 StandoutNobel
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Works of Roxana E. Georgescu being referenced
A peptide switch regulates DNA polymerase processivity
2003
CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication
2014
Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation
2016
A Sliding-Clamp Toolbelt Binds High- and Low-Fidelity DNA Polymerases Simultaneously
2005
Combining Conformational Flexibility and Continuum Electrostatics for Calculating pKas in Proteins
2002
Structure of a Sliding Clamp on DNA
2008
Heat capacity analysis of oxidized Escherichia coli thioredoxin fragments (1–73, 74–108) and their noncovalent complex
2001
Mechanism of the E. coli τ Processivity Switch during Lagging-Strand Synthesis
2003
Single‐molecule analysis of the Escherichia coli replisome and use of clamps to bypass replication barriers
2010
Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork
2014
The architecture of a eukaryotic replisome
2015
Crystal Structure of the Catalytic α Subunit of E. coli Replicative DNA Polymerase III
2006
Proline Isomerization-Independent Accumulation of an Early Intermediate and Heterogeneity of the Folding Pathways of a Mixed α/β Protein, Escherichia coli Thioredoxin
1998
Recognition between Disordered States: Kinetics of the Self-Assembly of Thioredoxin Fragments
1997
Replication Factor C Clamp Loader Subunit Arrangement within the Circular Pentamer and Its Attachment Points to Proliferating Cell Nuclear Antigen
2003
RECOGNITION BETWEEN DISORDERED POLYPEPTIDE CHAINS FROM CLEAVAGE OF AN α/β DOMAIN: SELF-VERSUS NON-SELF-ASSOCIATION
1998