Citation Impact
Citing Papers
HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing
2001 StandoutScienceNobel
Principles for designing proteins with cavities formed by curved β sheets
2017 StandoutScienceNobel
SNARE Proteins: One to Fuse and Three to Keep the Nascent Fusion Pore Open
2012 StandoutScienceNobel
Protein structure determination using metagenome sequence data
2017 StandoutScienceNobel
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
Signal Recognition Particle (SRP)-mediated Targeting and Sec-dependent Translocation of an Extracellular Escherichia coli Protein
2003
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
Structure of the signal recognition particle interacting with the elongation-arrested ribosome
2004 StandoutNatureNobel
SecB functions as a cytosolic signal recognition factor for protein export in E. coli
1989 StandoutNobel
Unity in Function in the Absence of Consensus in Sequence: Role of Leader Peptides in Export
1989 Science
Membrane protein structure prediction
1992
Nicastrin Functions as a γ-Secretase-Substrate Receptor
2005 StandoutNobel
Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin
1993 StandoutNatureNobel
SRP-mediated protein targeting: structure and function revisited
2004
The Escherichia coli SRP and SecB targeting pathways converge at the translocon
1998
The Tat protein export pathway
2000
Drosophila Rhomboid-1 Defines a Family of Putative Intramembrane Serine Proteases
2001
De novo design of integral membrane proteins
1994
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
Structure of the Type VI Secretion System Contractile Sheath
2015 StandoutNobel
A protein-conducting channel in the endoplasmic reticulum
1991 StandoutNobel
Basic Amino Acids in a Distinct Subset of Signal Peptides Promote Interaction with the Signal Recognition Particle
2003
Transcending the impenetrable: How proteins come to terms with membranes
1988
The ubiquitin-proteasome proteolytic pathway
1994 StandoutNobel
A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles
1994 StandoutNobel
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Regulated Intramembrane Proteolysis
2000
Cloning and expression of an inwardly rectifying ATP-regulated potassium channel
1993 Nature
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
2017 StandoutNatureNobel
Structural Basis of Inward Rectification
2002 StandoutNobel
New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor
1994 StandoutNatureNobel
Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization
2018 StandoutNatureNobel
The Protein Import Machinery of Mitochondria
2004
The karyogamy gene KAR2 and novel proteins are required for ER-membrane fusion
1994 StandoutNobel
Cryo-EM structure of the ribosome–SecYE complex in the membrane environment
2011
Electrostatic tuning of Mg2+ affinity in an inward-rectifier K+channel
1994 StandoutNatureNobel
Function of a chloroplast SRP in thylakoid protein export
2001
The structural basis of protein targeting and translocation in bacteria.
2001
Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex
1991 StandoutNatureNobel
Structure of the E. coli protein-conducting channel bound to a translating ribosome
2005 StandoutNatureNobel
Compartmental specificity of cellular membrane fusion encoded in SNARE proteins
2000 StandoutNatureNobel
Fluorescence Techniques for Studying Protein Structure
1991
Site-Specific Fluorescence Labeling of the β2Adrenergic Receptor Amino Terminus
1997 StandoutNobel
Crystal structure of a rhomboid family intramembrane protease
2006 Nature
Improved Prediction of Signal Peptides: SignalP 3.0
2004 Standout
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40
1993 StandoutNatureNobel
Peripheral deletion of self-reactive B cells
1991 Nature
A Chemosensory Gene Family Encoding Candidate Gustatory and Olfactory Receptors in Drosophila
2001 StandoutNobel
Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice
1992 StandoutNatureNobel
Design of activated serine–containing catalytic triads with atomic-level accuracy
2014 StandoutNobel
SEC21 is a gene required for ER to Golgi protein transport that encodes a subunit of a yeast coatomer
1992 StandoutNatureNobel
Structural basis of Sec-independent membrane protein insertion by YidC
2014 Nature
Binding of Secretory Precursor Polypeptides to a Translocon Subcomplex Is Regulated by BiP
1997 StandoutNobel
Requirements for Signal Peptide Peptidase-Catalyzed Intramembrane Proteolysis
2002
Membrane-protein integration and the role of the translocation channel
2004
The Structure and Insertion of Integral Proteins in Membranes
1990
The signal peptide
1990
Mechanisms of Sec61/SecY-Mediated Protein Translocation Across Membranes
2012
Signal recognition particle-depencent protein targeting, universal to all kingdoms of life
2002
Sec61p and BiP directly facilitate polypeptide translocation into the ER
1992 StandoutNobel
SRP-dependent co-translational targeting and SecA-dependent translocation analyzed as individual steps in the export of a bacterial protein
2000
The presence of a helix breaker in the hydrophobic core of signal sequences of secretory proteins prevents recognition by the signal‐recognition particle in Escherichia coli
2002
Functional Characterization of Recombinant Chloroplast Signal Recognition Particle
2001
Processing of Escherichia coli alkaline phosphatase: role of the primary structure of the signal peptide cleavage region 1 1Edited by A. R. Fersht
1998
Mechanisms of Protein Import and Routing in Chloroplasts
2004
The multicatalytic and 26 S proteases.
1993
Structural and functional dissection of Sec62p, a membrane-bound component of the yeast endoplasmic reticulum protein import machinery.
1990 StandoutNobel
Yeast syntaxins Sso1p and Sso2p belong to a family of related membrane proteins that function in vesicular transport.
1993
Fundamental Challenges in Mechanistic Enzymology: Progress toward Understanding the Rate Enhancements of Enzymes
2013
Regulation of Receptor Fate by Ubiquitination of Activated β 2 -Adrenergic Receptor and β-Arrestin
2001 StandoutScienceNobel
Prolyl 4-hydroxylase is required for viability and morphogenesis in Caenorhabditis elegans
2000
Topology and functional domains of Sec63p, an endoplasmic reticulum membrane protein required for secretory protein translocation.
1992 StandoutNobel
A structural model of the active ribosome-bound membrane protein insertase YidC
2014
Signal peptide cleavage regions. Functional limits on length and topological implications.
1994
Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter
1995 Standout
SecA protein, a peripheral protein of the Escherichia coli plasma membrane, is essential for the functional binding and translocation of proOmpA.
1989
Early events in preprotein recognition in E. coli: interaction of SRP and trigger factor with nascent polypeptides.
1995
Update 1 of: Proteases Universally Recognize Beta Strands In Their Active Sites
2010
Expression of a rat neurotensin receptor in Escherichia coli
1993 StandoutNobel
Topology and Functional Domains of Sec63p, an Endoplasmic Reticulum Membrane Protein Required for Secretory Protein Translocation
1992 StandoutNobel
Membrane insertion of the Escherichia coli MalF protein in cells with impaired secretion machinery.
1991
SEC11 is required for signal peptide processing and yeast cell growth.
1988 StandoutNobel
Structural and Functional Dissection of Sec62p, a Membrane-Bound Component of the Yeast Endoplasmic Reticulum Protein Import Machinery
1990 StandoutNobel
Clathrin: A Role in the Intracellular Retention of a Golgi Membrane Protein
1989 StandoutScienceNobel
A major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis
2005
Evidence that flavivirus NS1-NS2A cleavage is mediated by a membrane-bound host protease in the endoplasmic reticulum
1995
The Crystal Structure of the Signal Recognition Particle in Complex with Its Receptor
2011 StandoutScienceNobel
Interplay of signal recognition particle and trigger factor at L23 near the nascent chain exit site on theEscherichia coliribosome
2003
Solubilization and characterization of yeast signal peptidase
1989 StandoutNobel
Mutagenesis of the Signal Sequence of Yellow Fever Virus prM Protein: Enhancement of Signalase Cleavage In Vitro Is Lethal for Virus Production
2000 StandoutNobel
Structural Insights Into the Signal Recognition Particle
2004 StandoutNobel
Ligand crowding at a nascent signal sequence
2003
Flavivirus premembrane protein cleavage and spike heterodimer secretion require the function of the viral proteinase NS3.
1993
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
FtsY, the bacterial signal‐recognition particle receptor, interacts functionally and physically with the SecYEG translocon
2005
Insertion into the mitochondrial inner membrane of a polytopic protein, the nuclear-encoded Oxa1p
1997
On the transfer of integral proteins into membranes.
1987
Protein Translocation Across Biological Membranes
2005 StandoutScienceNobel
Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by Site-2 protease
2000 Nobel
Works of Ross Dalbey being referenced
Protein translocation into and across the bacterial plasma membrane and the plant thylakoid membrane
1999
Unconventional serine proteases: Variations on the catalytic Ser/His/Asp triad configuration
2008
Escherichia coli YidC is a membrane insertase for Sec‐independent proteins
2004
Positively charged residues are important determinants of membrane protein topology
1990
Defining the Regions of Escherichia coli YidC That Contribute to Activity
2003
Catalytic hydroxyl/amine dyads within serine proteases
1997
The structure and mechanism of bacterial type I signal peptidases
2000
The chemistry and enzymology of the type I signal peptidases
1997
Use of site-directed mutagenesis to define the limits of sequence variation tolerated for processing of the M13 procoat protein by the Escherichia coli leader peptidase
1991
Evidence for a Loop‐Like Insertion Mechanism of Pro‐Omp A into the Inner Membrane of Escherichia Coli
1994
Leader peptidase
1991
Charge Composition Features of Model Single-span Membrane Proteins That Determine Selection of YidC and SecYEG Translocase Pathways in Escherichia coli
2013
Determination ofKm andkcat for Signal Peptidase I Using a Full Length Secretory Precursor, pro-OmpA-nuclease A<//INF><//INF>
1995
Signal peptidases in prokaryotes and eukaryotes - a new protease family
1992
Direct Interaction of YidC with the Sec-independent Pf3 Coat Protein during Its Membrane Protein Insertion
2002
The Pf3 coat protein contacts TM1 and TM3 of YidC during membrane biogenesis
2008
Crystal structure of a bacterial signal peptidase in complex with a β-lactam inhibitor
1998 Nature
YidC mediates membrane protein insertion in bacteria
2000 Nature
YidC, an assembly site for polytopic Escherichia coli membrane proteins located in immediate proximity to the SecYE translocon and lipids
2001
Sec‐dependent membrane protein insertion: sequential interaction of nascent FtsQ with SecY and YidC
2001
Functional Analysis of the Signal Recognition Particle inEscherichia coliby Characterization of a Temperature-SensitiveffhMutant
2002
Signal Peptidases
2002
Versatility of inner membrane protein biogenesis in Escherichia coli
2003
YidC Is Strictly Required for Membrane Insertion of Subunits a and c of the F1F0ATP Synthase and SecE of the SecYEG Translocase
2003
Evolutionarily Related Insertion Pathways of Bacterial, Mitochondrial, and Thylakoid Membrane Proteins
2000
Foerster energy transfer measurements of thiol 1 to thiol 2 distances in myosin subfragment 1
1983
Erratum: Inserting proteins into the bacterial cytoplasmic membrane using the Sec and YidC translocases
2017
Use of phoA fusions to study the topology of the Escherichia coli inner membrane protein leader peptidase
1989
The translocation of negatively charged residues across the membrane is driven by the electrochemical potential: evidence for an electrophoresis-like membrane transfer mechanism.
1995
Mapping of catalytically important domains in Escherichia coli leader peptidase.
1990
Distinct domains of an oligotopic membrane protein are Sec-dependent and Sec-independent for membrane insertion.
1992
Mutational Evidence of Transition State Stabilization by Serine 88 in Escherichia coli Type I Signal Peptidase,
2000
Positive charges in the cytoplasmic domain of Escherichia coli leader peptidase prevent an apolar domain from functioning as a signal.
1989
Leader Peptidase of Escherichia coli : Critical Role of a Small Domain in Membrane Assembly
1987 Science
The internal signal sequence of Escherichia coli leader peptidase is necessary, but not sufficient, for its rapid membrane assembly.
1987
Charged residues render pro-OmpA potential dependent for initiation of membrane translocation
1993
The cytoplasmic domain of Escherichia coli leader peptidase is a "translocation poison" sequence.
1988
Leader peptidase catalyzes the release of exported proteins from the outer surface of the Escherichia coli plasma membrane.
1985
Identification of potential active-site residues in the Escherichia coli leader peptidase.
1992
Assembly of Bacterial Inner Membrane Proteins
2011
Translocation of N-terminal tails across the plasma membrane.
1994
The role of the polar, carboxyl-terminal domain of Escherichia coli leader peptidase in its translocation across the plasma membrane.
1986
Synergistic insertion of two hydrophobic regions drives Sec-independent membrane protein assembly.
1994