Citation Impact
Citing Papers
Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
2011 Standout
Orphan Nuclear Receptor ERRα Controls Macrophage Metabolic Signaling and A20 Expression to Negatively Regulate TLR-Induced Inflammation
2015
Immune Complex/Ig Negatively Regulate TLR4-Triggered Inflammatory Response in Macrophages through FcγRIIb-Dependent PGE2 Production
2009
The Tpl2 Mutation Sluggish Impairs Type I IFN Production and Increases Susceptibility to Group B Streptococcal Disease
2009 StandoutNobel
Group A Streptococcus Activates Type I Interferon Production and MyD88-dependent Signaling without Involvement of TLR2, TLR4, and TLR9
2008 StandoutNobel
MyD88 Adapter-like (Mal)/TIRAP Interaction with TRAF6 Is Critical for TLR2- and TLR4-mediated NF-κB Proinflammatory Responses
2009
IRAK1 and IRAK4 Promote Phosphorylation, Ubiquitination, and Degradation of MyD88 Adaptor-like (Mal)
2010
Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns
2010 Standout
Persistent kallikrein 5 activation induces atopic dermatitis-like skin architecture independent of PAR2 activity
2017 StandoutNobel
NF-κB signaling in inflammation
2017 Standout
Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists
2009
Interactions between the microbiota, immune and nervous systems in health and disease
2017 Standout
Inflammatory links between obesity and metabolic disease
2011 Standout
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
2010 Standout
Toll-like receptors as targets in chronic liver diseases
2009
SOCS proteins, cytokine signalling and immune regulation
2007 Standout
When Signaling Pathways Collide: Positive and Negative Regulation of Toll-like Receptor Signal Transduction
2008
What the Myddosome structure tells us about the initiation of innate immunity
2011
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
Shared Principles in NF-κB Signaling
2008 Standout
The interleukin‐1 receptor/Toll‐like receptor superfamily: 10 years of progress
2008
Cancer immunotherapy via dendritic cells
2012 Standout
TAM Receptors Are Pleiotropic Inhibitors of the Innate Immune Response
2007
Plant immunity: towards an integrated view of plant–pathogen interactions
2010 Standout
Complement: a key system for immune surveillance and homeostasis
2010 Standout
ROS Function in Redox Signaling and Oxidative Stress
2014 Standout
Intracellular Toll-like Receptors
2010 StandoutNobel
EMERGING PARADIGM
2006
The molecular basis of the host response to lipopolysaccharide
2009
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
NF-κB and the immune response
2006
Macrophages in Tissue Repair, Regeneration, and Fibrosis
2016 Standout
Modulation of adaptive immunity with Toll-like receptors
2009
Immunity, Inflammation, and Cancer
2010 Standout
Identification of a unique TGF-β–dependent molecular and functional signature in microglia
2013 Standout
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
2010 Standout
Regulation and Function of the PD-L1 Checkpoint
2018 Standout
IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage
2013 StandoutNobel
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
2010 Standout
TLR signaling
2007
SOCS regulation of the JAK/STAT signalling pathway
2008 Standout
Pyroptosis: host cell death and inflammation
2009 Standout
The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections
2007 StandoutNobel
Origin and physiological roles of inflammation
2008 StandoutNature
Phosphatase PTP1B negatively regulates MyD88- and TRIF-dependent proinflammatory cytokine and type I interferon production in TLR-triggered macrophages
2008
LPS/TLR4 signal transduction pathway
2008 Standout
Regulation of type I interferon responses
2013 Standout
Kallikrein-related Peptidase 4 (KLK4) Initiates Intracellular Signaling via Protease-activated Receptors (PARs)
2008
Post-Translational Modification Control of Innate Immunity
2016
Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets
2011 Standout
The PI3K Pathway in Human Disease
2017 Standout
A Dimer of the Toll-Like Receptor 4 Cytoplasmic Domain Provides a Specific Scaffold for the Recruitment of Signalling Adaptor Proteins
2007
TIR-containing adaptors in Toll-like receptor signalling
2009
Kupffer cells in non-alcoholic fatty liver disease: The emerging view
2009
Phosphoinositide-Mediated Adaptor Recruitment Controls Toll-like Receptor Signaling
2006
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
2007 Standout
NF- B in the Immune Response of Drosophila
2009 StandoutNobel
Exploring the full spectrum of macrophage activation
2008 Standout
Bruton's tyrosine kinase together with PI 3-kinase are part of Toll-like receptor 2 multiprotein complex and mediate LTA induced Toll-like receptor 2 responses in macrophages
2006
The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock
2012
Cytokine Signaling Modules in Inflammatory Responses
2008
Recognition and Signaling by Toll-Like Receptors
2006
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
2010 StandoutNobel
Immunometabolism governs dendritic cell and macrophage function
2015 Standout
Structure and Function of Toll Receptors and Their Ligands
2007
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
2008 StandoutNature
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
2011 StandoutNobel
MicroRNA-98 and let-7 Confer Cholangiocyte Expression of Cytokine-Inducible Src Homology 2-Containing Protein in Response to Microbial Challenge
2009
IFNγ-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice
2006
Intracellular Delivery of a Cell-Penetrating SOCS1 that Targets IFN-γ Signaling
2009
Toll‐like receptors in the brain and their potential roles in neuropathology
2007
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
NF-κB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1
2007
The Inflammasomes: Guardians of the Body
2009 Standout
TLRs and innate immunity
2008 StandoutNobel
Inflammatory Mechanisms in Obesity
2011 Standout
SOCS1, a Negative Regulator of Cytokine Signals and TLR Responses, in Human Liver Diseases
2010
Plant and Animal Sensors of Conserved Microbial Signatures
2010 StandoutScienceNobel
Lysosome-associated small Rab GTPase Rab7b negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4
2007
Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress
2015 StandoutNobel
Therapeutic Targeting of Toll-Like Receptors for Infectious and Inflammatory Diseases and Cancer
2009
Proteinase-Activated Receptors: Transducers of Proteinase-Mediated Signaling in Inflammation and Immune Response
2004
Physiology of Microglia
2011 Standout
Signaling Pathways Downstream of Pattern-Recognition Receptors and Their Cross Talk
2007
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of Rosealee Smith being referenced
Evidence for the activation of PAR‐2 by the sperm protease, acrosin: expression of the receptor on oocytes
2000
Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation
2006
Activation of Protease-Activated Receptor-2 Leads to Inhibition of Osteoclast Differentiation
2004