Citation Impact
Citing Papers
CTLA-4 Control over Foxp3 + Regulatory T Cell Function
2008 StandoutScienceNobel
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 StandoutScienceNobel
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
2003 StandoutNobel
Effective expansion of alloantigen-specific Foxp3 + CD25 + CD4 + regulatory T cells by dendritic cells during the mixed leukocyte reaction
2006 StandoutNobel
The Role of CD80, CD86, and CTLA4 in Alloimmune Responses and the Induction of Long-Term Allograft Survival
1999
CTLA4Ig: Bridging the Basic Immunology with Clinical Application
2006
Generation of mature dendritic cells from human blood An improved method with special regard to clinical applicability
1996
Virus replication begins in dendritic cells during the transmission of HIV-1 from mature dendritic cells to T cells
1999 StandoutNobel
Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade
2003
Regulatory T cells in transplantation
2002
Mechanisms of transplant tolerance induction using costimulatory blockade
2002
The role of B7 co‐stimulation in activation and differentiation ofCD4+and CD8+T cells
1998
TREATMENT WITH THE HUMANIZED CD154-SPECIFIC MONOCLONAL ANTIBODY, hu5C8, PREVENTS ACUTE REJECTION OF PRIMARY SKIN ALLOGRAFTS IN NONHUMAN PRIMATES1
2001
The role of the graft in establishing tolerance
2002
Human Cutaneous Dendritic Cells Migrate Through Dermal Lymphatic Vessels in a Skin Organ Culture Model
1996
The balance of deletion and regulation in allograft tolerance
2003
Reduction of atherosclerosis in mice by inhibition of CD40 signalling
1998 Nature
Regulatory T Cells
2000 StandoutNobel
CD154 on the surface of CD4+CD25+ regulatory t cells contributes to skin transplant tolerance
2003
DC-SIGN
2000 StandoutNobel
CD40 Ligation Releases Immature Dendritic Cells from the Control of Regulatory CD4+CD25+ T Cells
2003
CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells
2000
Stress Proteins and Immunology
1990
Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4.
1998
Developmental regulation of MHC class II transport in mouse dendritic cells
1997 StandoutNatureNobel
Impact of both donor and recipient strains on cardiac allograft survival after blockade of the CD40-CD154 costimulatory pathway1
2002
Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance
1999
Blockade of CD40L/CD40 costimulatory pathway in a DST presensitization model of islet allograft leads to a state of Allo-Ag specific tolerance and permits subsequent engraftment of donor strain islet or heart allografts
1999
Some interfaces of dendritic cell biology
2003 StandoutNobel
Dendritic cells in the T‐cell areas of lymphoid organs
1997 StandoutNobel
PROLONGED SURVIVAL OF MOUSE SKIN ALLOGRAFTS IN RECIPIENTS TREATED WITH DONOR SPLENOCYTES AND ANTIBODY TO CD40 LIGAND1
1997
Induction of transplantation tolerance—the potential of regulatory T cells
2005
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Regulatory T cells in transplantation tolerance
2003 StandoutNobel
Emergence of vancomycin tolerance in Streptococcus pneumoniae
1999 StandoutNatureNobel
The immunologic basis for the treatment of psoriasis with new biologic agents
2002
Atherosclerosis — An Inflammatory Disease
1999 Standout
Control of peripheral T‐cell tolerance and autoimmunity via the CTLA‐4 and PD‐1 pathways
2008
Regulatory T cells under scrutiny
2003
New use of BCG for recombinant vaccines
1991 StandoutNature
CD8+ T CELLS CONTRIBUTE TO THE DEVELOPMENT OF TRANSPLANT ARTERIOSCLEROSIS DESPITE CD154 BLOCKADE1
2000
COMMUNICATION MODULES IN BACTERIAL SIGNALING PROTEINS
1992
Asialo GM1+ CD8+ T cells play a critical role in costimulation blockade–resistant allograft rejection
1999
Vaccination of patients with B–cell lymphoma using autologous antigen–pulsed dendritic cells
1996 Standout
CD28-B7 T CELL COSTIMULATORY BLOCKADE BY CTLA4Ig IN THE RAT RENAL ALLOGRAFT MODEL1,2
1996
Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance
1999
Removing the Vertebrate-Specific TBP N Terminus Disrupts Placental β2m-Dependent Interactions with the Maternal Immune System
2002 StandoutNobel
Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors
1994
Protective Role of CD40 in Leishmania major Infection at Two Distinct Phases of Cell-Mediated Immunity
1996
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
The Immunobiology of Inductive Anti-CD40L Therapy in Transplantation: Allograft Acceptance is Not Dependent Upon the Deletion of Graft-Reactive T Cells
2002
A novel mechanism of glucocorticoid-induced immune suppression: the inhibiton of T cell-mediated terminal maturation of a murine dendritic cell line.
1996
Maturation and Migration of Cutaneous Dendritic Cells.
1995 StandoutNobel
The plant immune system
2006 StandoutNature
Involvement of CD40 Ligand-CD40 and CTLA4-B7 Pathways in Murine Acute Graft-Versus-Host Disease Induced by Allogeneic T Cells Lacking CD28
1998
IFN-γ Is Critical for Long-Term Allograft Survival Induced by Blocking the CD28 and CD40 Ligand T Cell Costimulation Pathways
1998
CD40 Ligand Blockade Induces CD4+ T Cell Tolerance and Linked Suppression
1999
Differences in dendritic cells stimulated in vivo by tumors engineered to secrete granulocyte-macrophage colony-stimulating factor or Flt3-ligand.
2000
Establishment of NOD-Pdcd1-/-mice as an efficient animal model of type I diabetes
2005 StandoutNobel
Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer
1997 StandoutNobel
Cytotoxic T Lymphocyte Antigen 4 (CTLA4) Blockade Accelerates the Acute Rejection of Cardiac Allografts in CD28-deficient Mice: CTLA4 Can Function Independently of CD28
1998
Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4+T cell responses
1999 StandoutNobel
CD40-CD40 Ligand-Independent Activation of CD8+ T Cells Can Trigger Allograft Rejection
2000
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Critical Role of OX40 in CD28 and CD154-Independent Rejection
2004
Early protection against pathogenic virus infection at a mucosal challenge site after vaccination with attenuated simian immunodeficiency virus
2004 StandoutNobel
Regulatory T Cells Overexpress a Subset of Th2 Gene Transcripts
2002
Cutting Edge: Anti-CD154 Therapeutic Antibodies Induce Infectious Transplantation Tolerance
2000
Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking
1998 StandoutScienceNobel
Dendritic cells with TGF-β1 differentiate naïve CD4+CD25−T cells into islet-protective Foxp3+regulatory T cells
2007 StandoutNobel
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Induction of cellular immunity by immunization with novel hybrid peptides complexed to heat shock protein 70
2000 StandoutNobel
Effector and Memory CTL Differentiation
2006
Type I IFNs Enhance the Terminal Differentiation of Dendritic Cells
1998
The complement dependent cytotoxicity (CDC) immune effector mechanism contributes to anti-CD154 induced immunosuppression.
2002
Efficient Presentation of Phagocytosed Cellular Fragments on the Major Histocompatibility Complex Class II Products of Dendritic Cells
1998 StandoutNobel
HOW DO MONOCLONAL ANTIBODIES INDUCE TOLERANCE? A Role for Infectious Tolerance?
1998
B7x: A widely expressed B7 family member that inhibits T cell activation
2003 StandoutNobel
Cutting Edge: CD4+CD25+ Alloantigen-Specific Immunoregulatory Cells That Can Prevent CD8+ T Cell-Mediated Graft Rejection: Implications for Anti-CD154 Immunotherapy
2002
The role of the graft in establishing tolerance
2002
Homeostasis and Self-Tolerance in the Immune System: Turning Lymphocytes off
1998 Science
Interaction of CTLA-4 with AP50, a clathrin-coated pit adaptor protein
1997 StandoutNobel
Maturation and Migration of Cutaneous Dendritic Cells
1995 StandoutNobel
TRANCE, a Tumor Necrosis Factor Family Member Critical for CD40 Ligand–independent T Helper Cell Activation
1999 StandoutNobel
Network of dendritic cells within the muscular layer of the mouse intestine
2005 StandoutNobel
Heat shock protein 70-associated peptides elicit specific cancer immunity.
1993
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
Blockade of T Lymphocyte Costimulation with Cytotoxic T Lymphocyte–Associated Antigen 4–Immunoglobulin (Ctla4ig) Reverses the Cellular Pathology of Psoriatic Plaques, Including the Activation of Keratinocytes, Dendritic Cells, and Endothelial Cells
2000
Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
2005 StandoutNobel
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
2003 StandoutNobel
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
The Yin and Yang of T Cell Costimulation
1995 StandoutScienceNobel
Replication of HIV-1 in Dendritic Cell-Derived Syncytia at the Mucosal Surface of the Adenoid
1996 StandoutScienceNobel
Transport of Peptide-MHC Class II Complexes in Developing Dendritic Cells
2000 StandoutScienceNobel
The Danger Model: A Renewed Sense of Self
2002 StandoutScience
Complexities of CD28/B7: CTLA-4 Costimulatory Pathways in Autoimmunity and Transplantation
2001
Alloantigen–induced specific immunological unresponsiveness
2001
The role of peripheral T–cell deletion in transplantation tolerance
2001
Treatment of Allograft Recipients with Donor-Specific Transfusion and Anti-CD154 Antibody Leads to Deletion of Alloreactive CD8+ T Cells and Prolonged Graft Survival in a CTLA4-Dependent Manner
2000
Rapid Infection of Oral Mucosal-Associated Lymphoid Tissue with Simian Immunodeficiency Virus
1999 StandoutScienceNobel
CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates
1997
Pinpointing when T cell costimulatory receptor CTLA-4 must be engaged to dampen diabetogenic T cells
2000 StandoutNobel
A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels
1998 StandoutNobel
Molecular cloning and sequence analysis of the Sta58 major antigen gene of Rickettsia tsutsugamushi: sequence homology and antigenic comparison of Sta58 to the 60-kilodalton family of stress proteins
1990
Induction of Salmonella Stress Proteins Upon Infection of Macrophages
1990 Science
CD40 AND CD154 IN CELL-MEDIATED IMMUNITY
1998
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
2010 StandoutNobel
Requirement for natural killer T (NKT) cells in the induction of allograft tolerance
2001
Dendritic Cells: Unique Leukocyte Populations Which Control the Primary Immune Response
1997
The Role of the IL-2 Pathway in Costimulation Blockade-Resistant Rejection of Allografts
2002
The B7 Family of Ligands and Its Receptors: New Pathways for Costimulation and Inhibition of Immune Responses
2002
IFN-gamma is critical for long-term allograft survival induced by blocking the CD28 and CD40 ligand T cell costimulation pathways.
1998
Enhancement of Antitumor Immunity by CTLA-4 Blockade
1996 StandoutScienceNobel
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Antibody to Langerin/CD207 localizes large numbers of CD8α + dendritic cells to the marginal zone of mouse spleen
2009 StandoutNobel
Analysis of the Underlying Cellular Mechanisms of Anti-CD154-Induced Graft Tolerance: The Interplay of Clonal Anergy and Immune Regulation
2005 StandoutNobel
Specific Suppression of Human CD4+ Th Cell Responses to Pig MHC Antigens by CD8+CD28− Regulatory T Cells
1998
Regulatory T Cells Induced by 1α,25-Dihydroxyvitamin D3 and Mycophenolate Mofetil Treatment Mediate Transplantation Tolerance
2001
Low levels of HIV-1 infection in cutaneous dendritic cells promote extensive viral replication upon binding to memory CD4+ T cells.
1995 StandoutNobel
Works of Rose Hendrix being referenced
ANALYSIS OF THE B7 COSTIMULATORY PATHWAY IN ALLOGRAFT REJECTION1
1997
CTLA4-Ig PLUS BONE MARROW INDUCES LONG-TERM ALLOGRAFT SURVIVAL AND DONOR-SPECIFIC UNRESPONSIVENESS IN THE MURINE MODEL
1996
Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways
1996 Nature
CD40-gp39 INTERACTIONS PLAY A CRITICAL ROLE DURING ALLOGRAFT REJECTION
1996
GENE EXPRESSION ANALYSIS IN HUMAN RENAL ALLOGRAFT BIOPSY SAMPLES USING HIGH-DENSITY OLIGOARRAY TECHNOLOGY1
2001
Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells.
1994
Development of a Chimeric Anti-CD40 Monoclonal Antibody That Synergizes with LEA29Y to Prolong Islet Allograft Survival
2005
Stress proteins are immune targets in leprosy and tuberculosis.
1988