Citation Impact
Citing Papers
The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans
2012 StandoutNobel
Circulating microRNA profiles in human patients with acetaminophen hepatotoxicity or ischemic hepatitis
2014 StandoutNobel
Characterization of a canine homolog of hepatitis C virus
2011 StandoutNobel
Evidence for a functional RNA element in the hepatitis C virus core gene
2007 StandoutNobel
Reconstituting Organ-Level Lung Functions on a Chip
2010 StandoutScience
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
2005 StandoutScience
Cytochrome P450 2B6: function, genetics, and clinical relevance
2012
Regulation of Type II Transmembrane Serine Proteinase TMPRSS6 by Hypoxia-inducible Factors
2010 StandoutNobel
Association between TCF7L2gene polymorphisms and susceptibility to Type 2 Diabetes Mellitus: a large Human Genome Epidemiology (HuGE) review and meta-analysis
2009
Productive Hepatitis C Virus Infection of Stem Cell-Derived Hepatocytes Reveals a Critical Transition to Viral Permissiveness during Differentiation
2012
Circulating microRNAs as potential markers of human drug-induced liver injury
2011
Genetic Predictors of Interindividual Variability in Hepatic CYP3A4 Expression
2009
The third dimension bridges the gap between cell culture and live tissue
2007 Standout
MicroRNAs Regulate Human Hepatocyte Nuclear Factor 4α, Modulating the Expression of Metabolic Enzymes and Cell Cycle
2009
Recapitulation of the hepatitis C virus life-cycle in engineered murine cell lines
2013 StandoutNobel
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Vascularized and functional human liver from an iPSC-derived organ bud transplant
2013 StandoutNature
Regulation of CYP3A genes in the human respiratory tract
2005
nhl-2 Modulates MicroRNA Activity in Caenorhabditis elegans
2009 StandoutNobel
Unconventional miR-122 binding stabilizes the HCV genome by forming a trimolecular RNA structure
2013 StandoutNobel
Integration of microRNA miR-122 in hepatic circadian gene expression
2009
Transcriptional Regulation of the Human Hepatic CYP3A4: Identification of a New Distal Enhancer Region Responsive to CCAAT/Enhancer-Binding Protein β Isoforms (Liver Activating Protein and Liver Inhibitory Protein)
2005
Gene-Specific Effects of Inflammatory Cytokines on Cytochrome P450 2C, 2B6 and 3A4 mRNA Levels in Human Hepatocytes
2007
Barriers of hepatitis C virus interspecies transmission
2012
Evolutionarily Conserved Roles of the Dicer Helicase Domain in Regulating RNA Interference Processing
2014 StandoutNobel
VALIDATED ASSAYS FOR HUMAN CYTOCHROME P450 ACTIVITIES
2004
MicroRNA-122 Modulates the Rhythmic Expression Profile of the Circadian Deadenylase Nocturnin in Mouse Liver
2010
Molecular Mechanism of Liver Development and Regeneration
2007
microRNA-122 stimulates translation of hepatitis C virus RNA
2008
Mammalian microRNAs predominantly act to decrease target mRNA levels
2010 StandoutNature
MicroRNAs: Target Recognition and Regulatory Functions
2009 Standout
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
The impact of microRNAs on protein output
2008 StandoutNature
Synergistically Enhanced CYP2B6 Inducibility between a Polymorphic Mutation in CYP2B6 Promoter and Pregnane X Receptor Activation
2010
Embryonic development of the liver†
2005
A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA
2011 Standout
Transcription Factor Binding to a Putative Double E-Box Motif Represses CYP3A4 Expression in Human Lung Cells
2007
Metazoan MicroRNAs
2018 Standout
Chapter 2 Cutting the Gordian Knot-Development and Biological Relevance of Hepatitis C Virus Cell Culture Systems
2008
Epigenetic Modulation of miR-122 Facilitates Human Embryonic Stem Cell Self-Renewal and Hepatocellular Carcinoma Proliferation
2011
Cationic lipid nanoparticles for therapeutic delivery of siRNA and miRNA to murine liver tumor
2013
Wnt/β-Catenin Signaling and Disease
2012 Standout
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
An efficient and sensitive method for preparing cDNA libraries from scarce biological samples
2014 StandoutNobel
An artificial liver sinusoid with a microfluidic endothelial‐like barrier for primary hepatocyte culture
2007
Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation
2008
INVOLVEMENT OF HEPATOCYTE NUCLEAR FACTOR 4α IN THE DIFFERENT EXPRESSION LEVEL BETWEEN CYP2C9 AND CYP2C19 IN THE HUMAN LIVER
2006
Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation
2016
Genetic programming of liver and pancreas progenitors: lessons for stem-cell differentiation
2008
Dual regulation of hepatitis C viral RNA by cellular RNAi requires partitioning of Ago2 to lipid droplets and P-bodies
2011
Diversifying microRNA sequence and function
2013
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Molecular mechanisms of genetic variation and transcriptional regulation of CYP2C19
2012
Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies
2007
Silencing of microRNAs in vivo with ‘antagomirs’
2005 StandoutNature
Lack of differences in diclofenac (a substrate for CYP2C9) pharmacokinetics in healthy volunteers with respect to the single CYP2C9 * 3 allele
2000
MicroRNAs in Human Cancer
2012
The Ligands of Estrogen Receptor α Regulate Cytochrome P4502C9 (CYP2C9) Expression
2011
The Transcriptional Regulation of the Human CYP2C Genes
2009
Highly Complementary Target RNAs Promote Release of Guide RNAs from Human Argonaute2
2013
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
A genetically humanized mouse model for hepatitis C virus infection
2011 StandoutNatureNobel
miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting
2006 Standout
Position-Dependent Function for a Tandem MicroRNA miR-122-Binding Site Located in the Hepatitis C Virus RNA Genome
2008
Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver
2012
Foxa2 integrates the transcriptional response of the hepatocyte to fasting
2005
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
2013 Standout
Reassessment of Exosome Composition
2019 Standout
Complexity of the microRNA repertoire revealed by next-generation sequencing
2010
Organogenesis and Development of the Liver
2010
New Insights into the Regulation of CYP2C9 Gene Expression: The Role of the Transcription Factor GATA-4
2009
MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis
2012
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma
2011 Standout
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
2023 StandoutNobel
MicroRNA signatures in liver diseases
2009
Regulation of Hepatitis C Virus Translation and Infectious Virus Production by the MicroRNA miR-122
2010
Modulation of Hepatitis C Virus RNA Abundance and the Isoprenoid Biosynthesis Pathway by MicroRNA miR-122 Involves Distinct Mechanisms
2009
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Characterization of nonprimate hepacivirus and construction of a functional molecular clone
2015 StandoutNobel
A role for Dicer in immune regulation
2006 StandoutNobel
Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBPα
2008
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
Relief of microRNA-Mediated Translational Repression in Human Cells Subjected to Stress
2006
MicroRNA-206 Is Highly Expressed in Newly Formed Muscle Fibers: Implications Regarding Potential for Muscle Regeneration and Maturation in Muscular Dystrophy
2008
The MicroRNA Spectrum in 12 Body Fluids
2010 Standout
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells
2012 StandoutNobel
Repression of Wnt/β-catenin signaling in the anterior endoderm is essential for liver and pancreas development
2007
Modulation of Hepatitis C Virus RNA Abundance by a Liver-Specific MicroRNA
2005 StandoutScience
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells
2011
Replication of Subgenomic Hepatitis C Virus Replicons in Mouse Fibroblasts Is Facilitated by Deletion of Interferon Regulatory Factor 3 and Expression of Liver-Specific MicroRNA 122
2010
Competing and noncompeting activities of miR-122 and the 5′ exonuclease Xrn1 in regulation of hepatitis C virus replication
2012
Base Pairing between Hepatitis C Virus RNA and MicroRNA 122 3′ of Its Seed Sequence Is Essential for Genome Stabilization and Production of Infectious Virus
2012
Circulating microRNAs, potential biomarkers for drug-induced liver injury
2009
REGULATION OF DRUG-METABOLIZING ENZYMES AND TRANSPORTERS IN INFLAMMATION
2005
Nascent-Seq analysis of Drosophila cycling gene expression
2013 StandoutNobel
Towards a small animal model for hepatitis C
2009 StandoutNobel
Stabilization of hepatitis C virus RNA by an Ago2–miR-122 complex
2012
CLINICAL AND TOXICOLOGICAL RELEVANCE OF CYP2C9: Drug-Drug Interactions and Pharmacogenetics
2005
Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides
2020 StandoutNobel
Works of Roque Bort being referenced
Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas
2004
Metabolism of aceclofenac in humans.
1996
Role of hepatocyte nuclear factor 3γ in the expression of human CYP2C genes
2004
Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin 6 dependent
2000
miR-122, a Mammalian Liver-Specific microRNA, is Processed from hcr mRNA and MayDownregulate the High Affinity Cationic Amino Acid Transporter CAT-1
2004
In vitro Investigation of the Molecular Mechanisms of Hepatotoxicity
1997
Re‐expression of C/EBPα induces CYP2B6, CYP2C9 and CYP2D6 genes in HepG2 cells
1998
Transcriptional Regulation of Human CYP3A4 Basal Expression by CCAAT Enhancer-Binding Protein α and Hepatocyte Nuclear Factor-3γ
2003
Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development
2005
Down‐regulation of human CYP3A4 by the inflammatory signal interleukin 6: molecular mechanism and transcription factors involved
2002
Comparative metabolism of the nonsteroidal antiinflammatory drug, aceclofenac, in the rat, monkey, and human.
1996
Diclofenac Toxicity to Hepatocytes: A Role for Drug Metabolism in Cell Toxicity
1999
Hepatic metabolism of diclofenac: role of human CYP in the minor oxidative pathways
1999
Long-term expression of differentiated functions in hepatocytes cultured in three-dimensional collagen matrix
1998