Citation Impact
Citing Papers
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
Human α- l -iduronidase uses its own N -glycan as a substrate-binding and catalytic module
2013
Production of butyrate from lysine and the Amadori product fructoselysine by a human gut commensal
2015
Formation of propionate and butyrate by the human colonic microbiota
2016 Standout
The Ternary Structure of the Double-headed Arrowhead Protease Inhibitor API-A Complexed with Two Trypsins Reveals a Novel Reactive Site Conformation
2009
Classification of fungal and bacterial lytic polysaccharide monooxygenases
2015
Csy4 relies on an unusual catalytic dyad to position and cleave CRISPR RNA
2012 StandoutNobel
Scoring functions for protein–protein interactions
2013 StandoutNobel
High throughput screening identifies disulfide isomerase DsbC as a very efficient partner for recombinant expression of small disulfide-rich proteins in E. coli
2013
Increased Flexibility as a Strategy for Cold Adaptation
2005
Absolute binding free energy calculations: On the accuracy of computational scoring of protein–ligand interactions
2010 StandoutNobel
Structural comparison of psychrophilic and mesophilic trypsins
2000
Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs)
2010
Cellular function and molecular structure of ecto-nucleotidases
2012
Selection and evolution of enzymes from a partially randomized non-catalytic scaffold
2007 StandoutNatureNobel
Modeling electrostatic effects in proteins
2006 StandoutNobel
Genetic associations with human longevity at the APOE and ACE loci
1994 Standout
Nucleotide signalling during inflammation
2014 StandoutNature
Reactive oxygen and oxidative stress: N-formyl kynurenine in photosystem II and non-photosynthetic proteins
2012
Molecular Evolution of a Small Gene Family of Wound Inducible Kunitz Trypsin Inhibitors in Populus
2006
Plant–microbiome interactions: from community assembly to plant health
2020 Standout
Flexibility and enzymatic cold-adaptation: A comparative molecular dynamics investigation of the elastase family
2006
Cloning and Characterization of Two Potent Kunitz Type Protease Inhibitors from Echinococcus granulosus
2015
Trypsin‐ligand binding free energies from explicit and implicit solvent simulations with polarizable potential
2009
The ClusPro web server for protein–protein docking
2017 Standout
Electrostatic effects play a central role in cold adaptation of trypsin
2001
Additivity-based prediction of equilibrium constants for some protein–protein associations
2003
Structural basis of bacterial defense against g-type lysozyme-based innate immunity
2012
Atomic resolution structures of trypsin provide insight into structural radiation damage
2001
Computational Design of Novel Protein Binders and Experimental Affinity Maturation
2013 StandoutNobel
Rosetta in CAPRI rounds 13–19
2010 StandoutNobel
Gut microbiome and health: mechanistic insights
2022 Standout
Probing the Effect of Point Mutations at Protein-Protein Interfaces with Free Energy Calculations
2005
Tissue Kallikrein Inhibitors Based on the Sunflower Trypsin Inhibitor Scaffold – A Potential Therapeutic Intervention for Skin Diseases
2016 StandoutNobel
Some like it cold: biocatalysis at low temperatures
2003
Psychrophilic enzymes: hot topics in cold adaptation
2003 Standout
Structural basis for thermostability revealed through the identification and characterization of a highly thermostable phosphotriesterase-like lactonase from Geobacillus stearothermophilus
2009
The catalytic pathway of horseradish peroxidase at high resolution
2002 StandoutNature
Residue determinants and sequence analysis of cold-adapted trypsins
1999
Hotspot-Centric De Novo Design of Protein Binders
2011 StandoutNobel
The expanding diversity of serine hydrolases
2007
Identification of epitope‐like consensus motifs using mRNA display
2002 StandoutNobel
The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities
2015 Standout
Design of activated serine–containing catalytic triads with atomic-level accuracy
2014 StandoutNobel
Computational Mapping of Anchoring Spots on Protein Surfaces
2010
A comprehensive examination of the contributions to the binding entropy of protein–ligand complexes
2010 StandoutNobel
Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation
2020 StandoutNobel
Calculations of solute and solvent entropies from molecular dynamics simulations
2006
Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability
2016 StandoutNobel
Experimental and Computational Analyses of the Energetic Basis for Dual Recognition of Immunity Proteins by Colicin Endonucleases
2008 StandoutNobel
Nucleases: diversity of structure, function and mechanism
2010
Free energy calculations show that acidic P1 variants undergo large pKa shifts upon binding to trypsin
2006
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Virtual screening using molecular simulations
2011
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
2010 StandoutNobel
Ligand Binding Affinities from MD Simulations
2002
Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems
2016
On the Relationship between Thermal Stability and Catalytic Power of Enzymes
2007 StandoutNobel
Steric and Dynamic Parameters Influencing In Situ Cycloadditions to Form Triazole Inhibitors with Crystalline Acetylcholinesterase
2016 StandoutNobel
Echinococcosis: Advances in the 21st Century
2019 Standout
Plant Immunity to Insect Herbivores
2007 Standout
Catalytic Effects of Mutations of Distant Protein Residues in Human DNA Polymerase β: Theory and Experiment
2012 StandoutNobel
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
2006
Linkage relationships of the gene for apolipoprotein CII with loci on chromosome 19
1985
Structural basis for the enhancement of virulence by viral spindles and their in vivo crystallization
2015
Redox Proteomics: Chemical Principles, Methodological Approaches and Biological/Biomedical Promises
2012
Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective
2010 Standout
Crystal Engineering of Self-Assembled Porous Protein Materials in Living Cells
2017 StandoutNobel
Reactive species in non-equilibrium atmospheric-pressure plasmas: Generation, transport, and biological effects
2016 Standout
Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide‐rich de novo designed peptides
2018 StandoutNobel
DNA origami protection and molecular interfacing through engineered sequence-defined peptoids
2020 StandoutNobel
Versatile Peptide C-Terminal Functionalization via a Computationally Engineered Peptide Amidase
2016 StandoutNobel
Progress in Ab Initio QM/MM Free-Energy Simulations of Electrostatic Energies in Proteins: Accelerated QM/MM Studies of pKa, Redox Reactions and Solvation Free Energies
2008 StandoutNobel
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
SKEMPI: a Structural Kinetic and Energetic database of Mutant Protein Interactions and its use in empirical models
2012
Operator-assisted harvesting of protein crystals using a universal micromanipulation robot
2007
Toward Accurate Microscopic Calculation of Solvation Entropies: Extending the Restraint Release Approach to Studies of Solvation Effects
2009 StandoutNobel
Efficient and Accurate Free Energy Calculations on Trypsin Inhibitors
2012
Nature Versus Nurture: Developing Enzymes That Function Under Extreme Conditions
2012
Cellular uptake of nanoparticles: journey inside the cell
2017 Standout
Bacterial Quorum-Sensing Network Architectures
2009 Standout
g_mmpbsa—A GROMACS Tool for High-Throughput MM-PBSA Calculations
2014 Standout
Simulating the electrostatic guidance of the vectorial translocations in hexameric helicases and translocases
2009 StandoutNobel
Reactive oxygen species, abiotic stress and stress combination
2016 Standout
System of sequences in multivariate reticular structures
2022 StandoutNobel
The Extracellular Nuclease Dns and Its Role in Natural Transformation of Vibrio cholerae
2008
Simulating the Effect of DNA Polymerase Mutations on Transition-State Energetics and Fidelity: Evaluating Amino Acid Group Contribution and Allosteric Coupling for Ionized Residues in Human Pol β
2006 StandoutNobel
Works of Ronny Helland being referenced
High-resolution structures of three new trypsin–squash-inhibitor complexes: a detailed comparison with other trypsins and their complexes
1999
The crystal structure of anionic salmon trypsin in complex with bovine pancreatic trypsin inhibitor
1998
The Structure of Bovine Lysosomal α-Mannosidase Suggests a Novel Mechanism for Low-pH Activation
2003
Substitutions at the P 1 ′ position in BPTI strongly affect the association energy with serine proteinases 1 1Edited by R. Huber
2000
The crystal structures of the complexes between bovine β-trypsin and ten P1 variants of BPTI
1999
Effects of salt on the kinetics and thermodynamic stability of endonuclease I from Vibrio salmonicida and Vibrio cholerae
2008
Crystallization and preliminary X-ray diffraction analysis of a cold-adapted uracil-DNA glycosylase from Atlantic cod (Gadus morhua)
2001
The 1.4 Å crystal structure of the large and cold-active Vibrio sp. alkaline phosphatase
2008
The 1.8 Å crystal structure of a proteinase K‐like enzyme from a psychrotroph Serratia species
2005
Crystal structures of g-type lysozyme from Atlantic cod shed new light on substrate binding and the catalytic mechanism
2009
An Oxidized Tryptophan Facilitates Copper Binding in Methylococcus capsulatus-secreted Protein MopE
2008
The structure ofVibrio choleraeextracellular endonuclease I reveals the presence of a buried chloride ion
2006
Thermodynamics and structure of a salmon cold active goose-type lysozyme
2010
Structural adaptation of endonuclease I from the cold-adapted and halophilic bacteriumVibrio salmonicida
2008
Trypsin specificity as elucidated by LIE calculations, X‐ray structures, and association constant measurements
2004
The locus for apolipoprotein E (apoE) is close to the Lutheran (Lu) blood group locus on chromosome 19
1984
Structural and functional characterization of a conserved pair of bacterial cellulose-oxidizing lytic polysaccharide monooxygenases
2014
Structure-dependent relationships between growth temperature of prokaryotes and the amino acid frequency in their proteins
2007
Electrostatics of mesophilic and psychrophilic trypsin isoenzymes: Qualitative evaluation of electrostatic differences at the substrate binding site
2000