Citation Impact
Citing Papers
Key role of the p110δ isoform of PI3K in B-cell antigen and IL-4 receptor signaling: comparative analysis of genetic and pharmacologic interference with p110δ function in B cells
2005
The p110β isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110γ
2008
Phosphoinositide 3-kinase γ/δ inhibition limits infarct size after myocardial ischemia/reperfusion injury
2006
A Diarylquinoline Drug Active on the ATP Synthase of Mycobacterium tuberculosis
2004 StandoutScience
iPLA2β: front and center in human monocyte chemotaxis to MCP-1
2008
The Gi-coupled P2Y12 Receptor Regulates Diacylglycerol-mediated Signaling in Human Platelets
2008
ERBB receptors and cancer: the complexity of targeted inhibitors
2005 Standout
The Regulation of Class IA PI 3-Kinases by Inter-Subunit Interactions
2010
Mechanisms of type-I- and type-II-interferon-mediated signalling
2005 Standout
Molecular regulation of mast cell activation
2006
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
2006 Standout
Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo
2005 Standout
PI3K signalling in inflammation
2014
Electronic monitoring of patient adherence to oral antihypertensive medical treatment: a systematic review
2009
Allergic airway hyperresponsiveness, inflammation, and remodeling do not develop in phosphoinositide 3-kinase γ–deficient mice
2009
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Isoform-specific phosphoinositide 3-kinase inhibitors as therapeutic agents
2003
Nucleotide signalling during inflammation
2014 StandoutNature
The role of PI3K in immune cells
2003
Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis
2005
Mammalian phosphoinositide kinases and phosphatases
2009 StandoutNobel
Class I PI3K in oncogenic cellular transformation
2008
Compliance with aspirin or placebo in the hypertension optimal treatment (HOT) study
1999
Chemoattractants and their receptors in homeostasis and inflammation
2004
Malignant astrocytic glioma: genetics, biology, and paths to treatment
2007 Standout
Akt Activation in Platelets Depends on Gi Signaling Pathways
2004
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
2005 Standout
PI3K in lymphocyte development, differentiation and activation
2003
IgE and mast cells in allergic disease
2012 Standout
Myocardial ischemia-reperfusion injury: a neglected therapeutic target
2013 Standout
Oxidative Stress in Pathogenesis of Chronic Obstructive Pulmonary Disease: Cellular and Molecular Mechanisms
2005
Over‐expression of the p110β but not p110α isoform of PI 3‐kinase inhibits motility in breast cancer cells
2004
Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils
2005
A systematic review of the associations between dose regimens and medication compliance
2001 Standout
The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder
2007 Standout
Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2
2004
Targeting phosphoinositide 3-kinase—Moving towards therapy
2007
Fcγ receptors as regulators of immune responses
2007 Standout
Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery
2005 Standout
Targeting the phosphoinositide 3-kinase pathway in cancer
2009 Standout
Phosphoinositide 3‐kinases in cell migration
2008
Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications
2006 Standout
Platelet Activation and Atherothrombosis
2007 Standout
PI3Kγ inhibition: towards an 'aspirin of the 21st century'?
2006
Toll-like receptor signalling
2004 Standout
The ATP-gated P2X1 Receptor Plays a Pivotal Role in Activation of Aspirin-treated Platelets by Thrombin and Epinephrine
2008 StandoutNobel
The development of allergic inflammation
2008 StandoutNature
Lipid signalling in disease
2008
Essential role for the p110δ phosphoinositide 3-kinase in the allergic response
2004 Nature
Mast Cell Biology: Introduction and Overview
2011
Structure of the Novel C-terminal Domain of Vacuolar Protein Sorting 30/Autophagy-related Protein 6 and Its Specific Role in Autophagy
2012 StandoutNobel
Characterization of p87PIKAP, a Novel Regulatory Subunit of Phosphoinositide 3-Kinase γ That Is Highly Expressed in Heart and Interacts with PDE3B
2006
PI3Kγ Modulates the Cardiac Response to Chronic Pressure Overload by Distinct Kinase-Dependent and -Independent Effects
2004
Signalling by PI3K isoforms: insights from gene-targeted mice
2005
The skin and hair as surrogate tissues for measuring the target effect of inhibitors of phosphoinositide-3-kinase signaling
2006
The emerging mechanisms of isoform-specific PI3K signalling
2010
Physical and mechanical regulation of macrophage phenotype and function
2014
Macrophage inflammatory protein–1α as a costimulatory signal for mast cell–mediated immediate hypersensitivity reactions
2005
Deconvolution of Buparlisib’s mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention
2017
Monomeric IgE and Mast Cell Development, Survival and Function
2011
Coordinated Signaling through Both G12/13 and Gi Pathways Is Sufficient to Activate GPIIb/IIIa in Human Platelets
2002
Macrophages as regulators of tumour immunity and immunotherapy
2019 Standout
Myocardial Reperfusion Injury
2007 Standout
PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting
2014
Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1
2006 StandoutNobel
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Dysregulated pH: a perfect storm for cancer progression
2011 Standout
Phosphatidylinositide 3-kinase γ regulates key pathologic responses to cholecystokinin in pancreatic acinar cells
2004
Assigning Functional Domains within the p101 Regulatory Subunit of Phosphoinositide 3-Kinase γ
2004
New developments in FcεRI regulation, function and inhibition
2007
AKT/PKB Signaling: Navigating the Network
2017 Standout
Platelets in atherothrombosis: lessons from mouse models
2005
The functions and regulation of the PTEN tumour suppressor
2012 Standout
Getting to the site of inflammation: the leukocyte adhesion cascade updated
2007 Standout
The PI3K Pathway in Human Disease
2017 Standout
Regulation of cardiac hypertrophy by intracellular signalling pathways
2006 Standout
Targeting PI3K signalling in cancer: opportunities, challenges and limitations
2009 Standout
Gi‐dependent and ‐independent mechanisms downstream of the P2Y12 ADP‐receptor
2004
Phosphoinositide 3-kinase signalling – which way to target?
2003
Mast cells in the development of adaptive immune responses
2005 Standout
Signaling through Gi Family Members in Platelets
2002
Integrated signalling pathways for mast-cell activation
2006 Standout
Central role of the P2Y12 receptor in platelet activation
2004
Adherence to Medication
2005 Standout
Antiplatelet therapy: in search of the 'magic bullet'
2003
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Protease-activated receptor 1 (PAR1) signalling desensitization is counteracted via PAR4 signalling in human platelets
2011 StandoutNobel
Inactivation of PI3Kγ and PI3Kδ distorts T-cell development and causes multiple organ inflammation
2007
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis
2009
Signalling through Class I PI3Ks in mammalian cells
2006
PI3K signalling in B- and T-lymphocytes: new developments and therapeutic advances
2012
Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2
2004
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
DAMP-sensing receptors in sterile inflammation and inflammatory diseases
2019 Standout
Therapeutic potential of phosphoinositide 3-kinase inhibitors
2004
The platelet P2Y12 receptor for adenosine diphosphate: congenital and drug-induced defects
2010
MAST CELLS AS “TUNABLE” EFFECTOR AND IMMUNOREGULATORY CELLS: Recent Advances
2005
Interventions for enhancing medication adherence
2014 Standout
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Modulation of epithelial neoplasia and lymphoid hyperplasia in PTEN +/- mice by the p85 regulatory subunits of phosphoinositide 3-kinase
2005
Vav Activation and Function as a Rac Guanine Nucleotide Exchange Factor in Macrophage Colony-Stimulating Factor-Induced Macrophage Chemotaxis
2005
The relative role of PLCβ and PI3Kγ in platelet activation
2005
Loss of PIP5KIβ demonstrates that PIP5KI isoform-specific PIP 2 synthesis is required for IP 3 formation
2008
Class IA Phosphoinositide 3-Kinase Regulates Heart Size and Physiological Cardiac Hypertrophy
2005
Phosphoinositide 3-Kinase : Diverse Roles in Immune Cell Activation
2004
Activation of Platelet Function Through G Protein–Coupled Receptors
2006
Leukocyte phosphoinositide-3 kinase γ is required for chemokine-induced, sustained adhesion under flow in vivo
2006
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Molecular pharmacology and antitumor activity of PX-866, a novel inhibitor of phosphoinositide-3-kinase signaling
2004
Biochemistry and Physiology of Cyclic Nucleotide Phosphodiesterases: Essential Components in Cyclic Nucleotide Signaling
2007 Standout
Coincident signals from GPCRs and receptor tyrosine kinases are uniquely transduced by PI3Kβ in myeloid cells
2016
The Pten/PI3K pathway governs the homeostasis of Vα14iNKT cells
2006 StandoutNobel
Impaired platelet responses to thrombin and collagen in AKT-1–deficient mice
2004
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Phosphoinositide 3-kinase γ plays a critical role in bleomycin-induced pulmonary inflammation and fibrosis in mice
2010
Works of Ronan Calvez being referenced
Use of a Microprocessor-Equipped Tablet Box in Monitoring Compliance with Antihypertensive Treatment
1992
Phosphoinositide 3-Kinase γ Is an Essential Amplifier of Mast Cell Function
2002
Requirement for PI 3-kinase γ in macrophage migration to MCP-1 and CSF-1
2003
Cigarette smoke triggers macrophage adhesion and activation: role of lipid peroxidation products and scavenger receptor
2003
PI3Kγ Adaptor Subunits Define Coupling to Degranulation and Cell Motility by Distinct PtdIns(3,4,5)P 3 Pools in Mast Cells
2009
Phosphoinositide 3-kinase γ: a key modulator in inflammation and allergy
2003
Resistance to thromboembolism in PI3Kγ‐deficient mice
2001