Citation Impact
Citing Papers
Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites
2009 StandoutScience
Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney
2006 StandoutNobel
Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys
2009 StandoutScience
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
2011 StandoutNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Glitazones and the management of insulin resistance: what they do and how might they be used
2004
Pathogenesis of type 2 diabetes mellitus
2004
Ets-1 is a critical regulator of Ang II-mediated vascular inflammation and remodeling
2005
Pharmacophore modeling and parallel screening for PPAR ligands
2007
Abdominal obesity and metabolic syndrome
2006 StandoutNature
Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase
1998 Standout
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Muscle-specific Pparg deletion causes insulin resistance
2003
Inflammation and metabolic disorders
2006 StandoutNature
Enhanced angiogenesis in obesity and in response to PPARγ activators through adipocyte VEGF and ANGPTL4 production
2008
Drug therapy of the metabolic syndrome: minimizing the emerging crisis in polypharmacy
2006
HDL-cholesterol and cardiovascular disease
2015
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Mechanisms linking obesity with cardiovascular disease
2006 StandoutNature
Inhibition of Phosphatidylinositol 3-Kinase Enhances Mitogenic Actions of Insulin in Endothelial Cells
2002
Structural determinants for the activation mechanism of the angiotensin II type 1 receptor differ for phosphoinositide hydrolysis and mitogen-activated protein kinase pathways
2003
Calmodulin-mediated Activation of Akt Regulates Survival of c-Myc-overexpressing Mouse Mammary Carcinoma Cells
2004
Induction of Cardiac Fibrosis by Transforming Growth Factor-β1
2000
Molecular and physiologic actions of insulin related to production of nitric oxide in vascular endothelium
2003
Peroxisome Proliferator-Activated Receptor Gamma Agonist Ligands Stimulate a Th2 Cytokine Response and Prevent Acute Colitis
2002
Effect of Pioglitazone Compared With Glimepiride on Carotid Intima-Media Thickness in Type 2 Diabetes
2006
Cytokines in Atherosclerosis: Pathogenic and Regulatory Pathways
2006
Liver X receptors as integrators of metabolic and inflammatory signaling
2006
Peroxisome proliferator-activated receptor γ in diabetes and metabolism
2004
Mobilization of pro-inflammatory lipids in obese Plscr3-deficient mice
2007
Adipokines: molecular links between obesity and atheroslcerosis
2005
Comparison of the Release of Adipokines by Adipose Tissue, Adipose Tissue Matrix, and Adipocytes from Visceral and Subcutaneous Abdominal Adipose Tissues of Obese Humans
2004
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Minireview: Lipid Metabolism, Metabolic Diseases, and Peroxisome Proliferator-Activated Receptors
2003
The changing landscape of atherosclerosis
2021 StandoutNature
Magnesium Replacement Improves the Metabolic Profile in Obese and Pre-Diabetic Patients with Mild-to-Moderate Chronic Kidney Disease: A 3-Month, Randomised, Double-Blind, Placebo-Controlled Study
2017 Standout
Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARα, β/δ, and γ
2004
Macrophage death and defective inflammation resolution in atherosclerosis
2009
Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats
1999
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
2007 StandoutNature
Peroxisome proliferator–activated receptor γ ligands inhibit development of atherosclerosis in LDL receptor–deficient mice
2000
Peroxisome proliferator-activated receptor-γ ligands reduce inflammation and infarction size in transient focal ischemia
2004
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Regulation of blood pressure, natriuresis and renal thiazide/amiloride sensitivity in PPARα null mice
2008
Use of the Peroxisome Proliferator-Activated Receptor (PPAR) γ Ligand Troglitazone as Treatment for Refractory Breast Cancer: A Phase II Study
2003
Protein folding in the cell
1992 StandoutNature
Increased vascular contractility in isolated vessels from cigarette smoking rats is mediated by basal endothelin release
2006
Stabilization of atherosclerotic plaques: New mechanisms and clinical targets
2002
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
2005 StandoutNature
Dysfunctional fat cells, lipotoxicity and type 2 diabetes
2004
Metabolic Reprogramming in Dietary Restriction
2006
Mechanisms linking obesity to insulin resistance and type 2 diabetes
2006 StandoutNature
β-Arrestin 2-Dependent Angiotensin II Type 1A Receptor-Mediated Pathway of Chemotaxis
2005 StandoutNobel
Combinatorial roles of nuclear receptors in inflammation and immunity
2005
Origin and physiological roles of inflammation
2008 StandoutNature
The hormone resistin links obesity to diabetes
2001 StandoutNature
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
Biochemistry and molecular cell biology of diabetic complications
2001 StandoutNature
Molecular pathways regulating EGF-induced epithelio-mesenchymal transition in human ovarian surface epithelium
2006
Progress and challenges in translating the biology of atherosclerosis
2011 StandoutNature
Treatment of active psoriatic arthritis with the PPAR ligand pioglitazone: an open-label pilot study
2004
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
2003
Neovascularization of ischemic myocardium by human bone-marrow–derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function
2001 Standout
The Hallmarks of Aging
2013 Standout
Inflammation, Atherosclerosis, and Coronary Artery Disease
2005 Standout
Hypochlorite-oxidized low-density lipoprotein upregulates CD36 and PPARγ mRNA expression and modulates SR-BI gene expression in murine macrophages
2005
Endothelin‐1 impairs glucose transporter trafficking via a membrane‐based mechanism
2005
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
2011 StandoutNature
The role of PPAR-γ in macrophage differentiation and cholesterol uptake
2001
Crosstalk between LXR and Toll-like Receptor Signaling Mediates Bacterial and Viral Antagonism of Cholesterol Metabolism
2003
Retinoid X Receptor Heterodimers in the Metabolic Syndrome
2005
Bifidobacteria can protect from enteropathogenic infection through production of acetate
2011 StandoutNature
Insulin Resistance Is Associated with Impaired Nitric Oxide Synthase Activity in Skeletal Muscle of Type 2 Diabetic Subjects
2005
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
2011 StandoutNature
Endothelial Progenitor Cells and Vascular Biology in Diabetes Mellitus: Current Knowledge and Future Perspectives
2005
Metabolic syndrome: Definition, pathophysiology, and mechanisms
2005
Modulation of C-Reactive Protein–Mediated Monocyte Chemoattractant Protein-1 Induction in Human Endothelial Cells by Anti-Atherosclerosis Drugs
2001
Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARα, β/δ, and γ
2004
Peroxisome Proliferator–Activated Receptor γ and Metabolic Disease
2001
From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus
2009 Standout
Development of Monocytes, Macrophages, and Dendritic Cells
2010 StandoutScience
Expression of CD68 and Macrophage Chemoattractant Protein-1 Genes in Human Adipose and Muscle Tissues
2005
Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction
2006 Standout
Diabetes and Endothelial Dysfunction: A Clinical Perspective
2001
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
2003 StandoutNobel
Analysis of rna initiated in isolated mouse myeloma nuclei using purine nucleoside 5′[γ-S]triphosphates as affinity probes
1978
Fat and Beyond: The Diverse Biology of PPARγ
2008 Standout
Role of the Adipocyte, Free Fatty Acids, and Ectopic Fat in Pathogenesis of Type 2 Diabetes Mellitus: Peroxisomal Proliferator-Activated Receptor Agonists Provide a Rational Therapeutic Approach
2004
Conditional Disruption of the Peroxisome Proliferator-Activated Receptor γ Gene in Mice Results in Lowered Expression of ABCA1, ABCG1, and apoE in Macrophages and Reduced Cholesterol Efflux
2002
Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene
2004 StandoutNobel
Angiotensin Type 1 Receptor Blockers Induce Peroxisome Proliferator–Activated Receptor-γ Activity
2004
Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.
1994
Peroxisome Proliferator-Activated Receptor γ and Adipose Tissue—Understanding Obesity-Related Changes in Regulation of Lipid and Glucose Metabolism
2006
International Union of Pharmacology. XXIII. The Angiotensin II Receptors
2000 Standout
Hyperresistinemia Is Associated With Coexistence of Hypertension and Type 2 Diabetes
2008
Palmitate-Induced Interleukin-6 Expression in Human Coronary Artery Endothelial Cells
2004
Protein Sorting to Mitochondria: Evolutionary Conservations of Folding and Assembly
1990 Science
Mouse models of PPAR-γ deficiency: dissecting PPAR-γ's role in metabolic homoeostasis
2005
Transcriptional Suppression of Type 1 Angiotensin II Receptor Gene Expression by Peroxisome Proliferator-Activated Receptor-γ in Vascular Smooth Muscle Cells*
2001
The Effect of Thiazolidinediones on Plasma Adiponectin Levels in Normal, Obese, and Type 2 Diabetic Subjects
2002
G972R IRS-1 Variant Impairs Insulin Regulation of Endothelial Nitric Oxide Synthase in Cultured Human Endothelial Cells
2004
The PPARs: From Orphan Receptors to Drug Discovery
2000 Standout
Inflamed Adipose Tissue
2007
Nitrolinoleic acid: An endogenous peroxisome proliferator-activated receptor γ ligand
2005
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
2005 StandoutNobel
Transcriptional Suppression of Type 1 Angiotensin II Receptor Gene Expression by Peroxisome Proliferator-Activated Receptor- in Vascular Smooth Muscle Cells
2001
Molecular Mechanisms of Insulin Resistance That Impact Cardiovascular Biology
2004
Oxidized omega-3 fatty acids in fish oil inhibit leukocyte-endothelial interactions through activation of PPARα
2002
The Metabolic Syndrome
2008 Standout
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
Oxysterol and 9-cis-retinoic acid stimulate the group IIA secretory phospholipase A2 gene in rat smooth-muscle cells
2003
NUCLEAR RECEPTORS IN MACROPHAGE BIOLOGY: At the Crossroads of Lipid Metabolism and Inflammation
2004
Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice
2009 StandoutNobel
Quantum dot/antibody conjugates for in vivo cytometric imaging in mice
2015 StandoutNobel
A Macrophage Factor Inhibits Adipocyte Gene Expression: An in Vitro Model of Cachexia
1985 StandoutScienceNobel
Homeostasis Model Assessment of Insulin Resistance in Relation to the Incidence of Cardiovascular Disease
2002
IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation
1997 StandoutScience
New Insights Into the Regulation of HDL Metabolism and Reverse Cholesterol Transport
2005
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Insulin Resistance and Atherosclerosis
2006
Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults--The Evidence Report. National Institutes of Health.
1998 Standout
Osteopontin at the Crossroads of Inflammation and Tumor Progression
2017
Role of the Vascular Endothelial Growth Factor Pathway in Tumor Growth and Angiogenesis
2004 Standout
The insulin resistance syndrome: physiological considerations
2007
Weight Loss–Associated Induction of Peroxisome Proliferator–Activated Receptor-α and Peroxisome Proliferator–Activated Receptor-γ Correlate With Reduced Atherosclerosis and Improved Cardiovascular Function in Obese Insulin-Resistant Mice
2004
Works of Ronald E. Law being referenced
Inhibitory Activity of Clinical Thiazolidinedione Peroxisome Proliferator Activating Receptor-γ Ligands Toward Internal Mammary Artery, Radial Artery, and Saphenous Vein Smooth Muscle Cell Proliferation
2003
The central role of fat and effect of peroxisome proliferator-activated receptor–γ on progression of insulin resistance and cardiovascular disease
2003
Troglitazone inhibits angiotensin II‐induced extracellular signal‐regulated kinase 1/2 nuclear translocation and activation in vascular smooth muscle cells
1999
Vascular effects of TZDs: New implications
2006
PGE2 is generated by specific COX-2 activity and increases VEGF production in COX-2-expressing human pancreatic cancer cells
2003
Inhibition of MAP kinase blocks insulin‐mediated DNA synthesis and transcriptional activation of c‐fos by Elk‐1 in vascular smooth muscle cells
1997
Cardiovascular risk continuum: implications of insulin resistance and diabetes
1998
Troglitazone inhibits angiotensin II‐induced DNA synthesis and migration in vascular smooth muscle cells
1997
PPARγ-mediated insulin sensitization: the importance of fat versus muscle
2005
Protein kinase C inhibitors induce apoptosis in human malignant glioma cell lines
1994
Angiotensin II–accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice
2003
Mitogen-Activated Protein Kinase Activation Mediates PDGF- Directed Migration of RPE Cells
1998
TNFα induces expression of transcription factors c-fos, Egr-1, and Ets-1 in vascular lesions through extracellular signal-regulated kinases 1/2
2001
Insulin signaling in the arterial wall
1999
Peroxisome proliferator-activated receptor and retinoid X receptor ligands inhibit monocyte chemotactic protein-1-directed migration of monocytes
2000
Troglitazone Inhibits Growth of MCF-7 Breast Carcinoma Cells by Targeting G1 Cell Cycle Regulators
2001
Insulin and angiotensin II are additive in stimulating TGF-β1 and matrix mRNAs in mesangial cells
1996
PPARγ-Ligands Inhibit Migration Mediated by Multiple Chemoattractants in Vascular Smooth Muscle Cells
1999
Angiotensin II Has Multiple Profibrotic Effects in Human Cardiac Fibroblasts
2000
PPARγ and Atherosclerosis
2001
Expression and Function of PPARγ in Rat and Human Vascular Smooth Muscle Cells
2000
Angiotensin II–accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice
2003
Lipopolysaccharide-Induced NF-κB Activation in Mouse 70Z/3 Pre-B Lymphocytes Is Inhibited by Mevinolin and 5′-Methylthioadenosine: Roles of Protein Isoprenylation and Carboxyl Methylation Reactions
1992
Peroxisome Proliferator–Activated Receptor Activators Target Human Endothelial Cells to Inhibit Leukocyte–Endothelial Cell Interaction
1999
Effect of 5′‐methylthioadenosine on gene action during heat shock in Drosophila melanogaster
1979
Obesity, Peroxisome Proliferator-Activated Receptor, and Atherosclerosis in Type 2 Diabetes
2005
Liver X Receptor Agonists Inhibit Cytokine-Induced Osteopontin Expression in Macrophages Through Interference With Activator Protein-1 Signaling Pathways
2005
Central Role of the MAPK Pathway in Ang II–Mediated DNA Synthesis and Migration in Rat Vascular Smooth Muscle Cells
1999
Transcriptional Repression of ATP-Binding Cassette Transporter A1 Gene in Macrophages
2005
Control of Vascular Cell Proliferation and Migration by PPAR-γ
2001
Leptin Induces Endothelial Cell Migration Through Akt, Which Is Inhibited by PPARγ-Ligands
2002
Troglitazone Inhibits Formation of Early Atherosclerotic Lesions in Diabetic and Nondiabetic Low Density Lipoprotein Receptor–Deficient Mice
2001
PPARα Inhibits TGF-β–Induced β 5 Integrin Transcription in Vascular Smooth Muscle Cells by Interacting With Smad4
2002
Synthetic LXR ligand inhibits the development of atherosclerosis in mice
2002
Angiotensin II and α v β 3 Integrin Expression in Rat Neonatal Cardiac Fibroblasts
2000
Minireview: Adiposity, Inflammation, and Atherogenesis
2003
Inhibition of RNA synthesis in salivary glands of by 5′-methylthioadenosine
1976
Mitogen-Activated Protein Kinase Activation Is Involved in Platelet-Derived Growth Factor-Directed Migration by Vascular Smooth Muscle Cells
1997
Angiotensin II Induces Migration and Pyk2/Paxillin Phosphorylation of Human Monocytes
2001