Standout Papers
Citation Impact
Citing Papers
Sleep Drives Metabolite Clearance from the Adult Brain
2013 StandoutScience
Monoclonal antibodies inhibit in vitro fibrillar aggregation of the Alzheimer beta-amyloid peptide.
1996
Nicastrin Functions as a γ-Secretase-Substrate Receptor
2005 StandoutNobel
Amyloid β Protein (Aβ) in Alzheimeri's Disease Brain
1995
Amyloid β protein (Aβ) deposition: Aβ42(43) precedes Aβ40 in down Syndrome
1995
Presenilins are essential for regulating neurotransmitter release
2009 StandoutNatureNobel
NMR structure of the mouse prion protein domain PrP(121–231)
1996 StandoutNatureNobel
Cerebrovascular transport of Alzheimer's amyloidβ and apolipoproteins J and E: Possible anti-amyloidogenic role of the blood-brain barrier
1996
X11 Interaction with β-Amyloid Precursor Protein Modulates Its Cellular Stabilization and Reduces Amyloid β-Protein Secretion
1998
Is systemically administered oxytocin an analgesic in rats?
1994
Amyloid β-Protein Inhibits Ubiquitin-dependent Protein Degradation in Vitro
1995
Detecting prion protein gene mutations by denaturing gradient gel electrophoresis
1994 StandoutNobel
Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ42(43)
1994 Standout
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
2000 StandoutNature
The role of central oxytocin in obsessive compulsive disorder and related normal behavior
1994
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
1998 StandoutNature
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide
2007 Standout
Plasma Levels of amyloid β proteins Aβ1–40 and Aβ1–42(43) are elevated in Down's syndrome
1997
Rapid induction of Alzheimer A beta amyloid formation by zinc
1994 Science
Secretion of β-amyloid precursor protein cleaved at the amino terminus of the β-amyloid peptide
1993 Nature
Parkinson's disease: clinical features and diagnosis
2008 Standout
Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions
1993
Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid β protein precursor
1993
BIOLOGY AND GENETICS OF PRION DISEASES
1994
Ectodomain Phosphorylation of β-Amyloid Precursor Protein at Two Distinct Cellular Locations
1997
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
2002 StandoutNature
Genetics and molecular advances in Alzheimer's disease
1993
Aggregation of Secreted Amyloid β-Protein into Sodium Dodecyl Sulfate-stable Oligomers in Cell Culture
1995
Oxytocin acts as an antidepressant in two animal models of depression
1987
Botulinum toxin in the treatment of tremors, dystonias, sialorrhea and other symptoms associated with Parkinson’s disease
2007
Structural model for the β-amyloid fibril based on interstrand alignment of an antiparallel-sheet comprising a C-terminal peptide
1995
The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease
1998
Genetic and Infectious Prion Diseases
1993
Protein folding and misfolding
2003 StandoutNature
Joint and skeletal deformities in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy
2006
Gonadal Steroids have Paradoxical Effects on Brain Oxytocin Receptors
1993
Presenilin-1 differentially facilitates endoproteolysis of the β-amyloid precursor protein and Notch
2000
Ubiquitin C-Terminal Hydrolase Is an Immediate-Early Gene Essential for Long-Term Facilitation in Aplysia
1997 StandoutNobel
Water-soluble Aβ(N-40, N-42) Oligomers in Normal and Alzheimer Disease Brains
1996
Dominant and differential deposition of distinct β-amyloid peptide species, AβN3(pE), in senile plaques
1995
Non-A.beta. Component of Alzheimer's Disease Amyloid (NAC) is Amyloidogenic
1995
The carboxy terminus of the .beta. amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
1993 Standout
"Friendly fire" in medicine: hormones, homografts, and Creutzfeldt-Jakob disease
1992
Influence of oxytocin on feeding behavior in the rat
1989
Oxytocin inhibits food and fluid intake in rats
1990
Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments
1994 Nature
Neurohypophyseal hormones and excessive grooming behaviour
1990
Receptor-Mediated Transport of Human Amyloid β-Protein 1–40 and 1–42 at the Blood–Brain Barrier
1999
Morphology and Toxicity of Aβ-(1-42) Dimer Derived from Neuritic and Vascular Amyloid Deposits of Alzheimer's Disease
1996
Medical Management of Levodopa-Associated Motor Complications in Patients with Parkinson???s Disease
2007
Rapid Communication: Characterization of β‐Amyloid Peptide from Human Cerebrospinal Fluid
1993
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
Amyloid-β forms fibrils by nucleated conformational conversion of oligomers
2011
Injection of Oxytocin into the Medial Preoptic–Anterior Hypothalamus Increases Ultrasound Production by Female Hamsters
1998
Age-related cognitive deficits, impaired long-term potentiation and reduction in synaptic marker density in mice lacking the β-amyloid precursor protein
1999
The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways
1998
Mutagenesis Identifies New Signals for β-Amyloid Precursor Protein Endocytosis, Turnover, and the Generation of Secreted Fragments, Including Aβ42
1999
Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein
1993
Sorting through the Cell Biology of Alzheimer's Disease: Intracellular Pathways to Pathogenesis
2006
Formation of stable complexes between two Alzheimer's disease gene products: Presenilin-2 and β-amyloid precursor protein
1997
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
1995 StandoutNobel
Effects of nonapeptide antagonists on oxytocin- and arginine-vasopressin-induced analgesia in mice
1987
The Swedish mutation causes early-onset Alzheimer's disease by β-secretase cleavage within the secretory pathway
1995
Seeding “one-dimensional crystallization” of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?
1993 Standout
Elevated Cerebrospinal Fluid Levels of Oxytocin in Obsessive-compulsive Disorder
1994
Polyclonals to β-amyloid(1–42) identify most plaque and vascular deposits in Alzheimer cortex, but not striatum
1994
Translating cell biology into therapeutic advances in Alzheimer's disease
1999 Nature
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
High tissue content of soluble beta 1-40 is linked to cerebral amyloid angiopathy.
1994
Circumventing tolerance to generate autologous monoclonal antibodies to the prion protein.
1996 StandoutNobel
Release of Excess Amyloid β Protein from a Mutant Amyloid β Protein Precursor
1993 Science
Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice
1997 StandoutNobel
Notch receptor cleavage depends on but is not directly executed by presenilins
2002 StandoutNobel
Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production
1992 StandoutNature
Prion-inducing domain 2–114 of yeast Sup35 protein transforms in vitro into amyloid-like filaments
1997 StandoutNobel
Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP).
1994
Vasopressin Injected into the Hypothalamus Triggers a Stereotypic Behavior in Golden Hamsters
1984 Science
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation
1997 StandoutNobel
Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice
1996 StandoutScience
Polarized secretion of beta-amyloid precursor proteinand amyloid beta-peptide in MDCK cells.
1994
An Increased Percentage of Long Amyloid β Protein Secreted by Familial Amyloid β Protein Precursor (βApp 717 ) Mutants
1994 StandoutScience
MUTANT GENES IN FAMILIAL ALZHEIMER'S DISEASE AND TRANSGENIC MODELS
1998
A Century of Alzheimer's Disease
2006 StandoutScience
Accelerated A Deposition in APPswe/PS1 E9 Mice with Hemizygous Deletions of TTR (Transthyretin)
2007
Camptocormia
2005
Secreted Forms of the Amyloid-β Precursor Protein Are Ligands for the Class A Scavenger Receptor
2001
Oxytocin improves male copulatory performance in rats
1985
Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative.
1994
Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease
1997 StandoutScience
Creutzfeldt-Jakob disease in England and Wales, 1980-1984: a case-control study of potential risk factors.
1988
Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus.
1996 StandoutNobel
Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells.
1993
Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform.
1995 StandoutNobel
Marked decrease of neuropeptide Y Y2 receptor binding sites in the hippocampus in murine prion disease
1997 StandoutNobel
Mechanism of the cleavage specificity of Alzheimer’s disease γ-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein
1999
Calcium and neuronal injury in Alzheimer's disease. Contributions of beta-amyloid precursor protein mismetabolism, free radicals, and metabolic compromise.
1994
Oxytocin stimulates lordosis behavior in female rats
1985
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage
2004 StandoutNobel
Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members
2001 StandoutNobel
Double-knockout mice for α- and β-synucleins: Effect on synaptic functions
2004 StandoutNobel
Alzheimer's Disease: Genes, Proteins, and Therapy
2001 Standout
Creutzfeldt-Jakob Disease in Pituitary Growth Hormone Recipients in the United States
1991
A comparison of grooming behavior potencies of neurohypophyseal nonapeptides
1986
Prion Diseases and the BSE Crisis
1997 StandoutScienceNobel
Calcium and Neuronal Injury in Alzheimer's Disease
1994
Alzheimer's Disease Is a Synaptic Failure
2002 StandoutScience
Transthyretin sequesters amyloid beta protein and prevents amyloid formation.
1994
Selective ectodomain phosphorylation and regulated cleavage of beta-amyloid precursor protein.
1994
Alzheimer's Disease: Molecular Understanding Predicts Amyloid-Based Therapeutics
2003
Central nervous system actions of oxytocin and modulation of behavior in humans
1997
Generation of Alzheimer β-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation
1997
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease.
1993
Behavioral effects of intracerebroventricularly administered neurohypophyseal hormone analogs in mice
1982
Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains
1996 StandoutNobel
Induction of maternal behavior in virgin rats after intracerebroventricular administration of oxytocin
1979
beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.
1993
Chemical characterization of A beta 17-42 peptide, a component of diffuse amyloid deposits of Alzheimer disease
1994
Polarized sorting of beta-amyloid precursor protein and its proteolytic products in MDCK cells is regulated by two independent signals.
1995
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Interactive effects of intracisternal oxytocin and other centrally active substances on colonic temperatures of mice
1986
The 3D profile method for identifying fibril-forming segments of proteins
2006 StandoutNobel
The Oxytocin Receptor System: Structure, Function, and Regulation
2001 Standout
Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein.
1994 StandoutNobel
beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease.
1993
Evidence that production and release of amyloid beta-protein involves the endocytic pathway
1994
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
2004 StandoutNobel
Mutations associated with a locus for familial Alzheimer's disease result in alternative processing of amyloid beta-protein precursor
1994
On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants.
1996
Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis
2003 StandoutScience
Etiology and pathogenesis of prion diseases.
1995 StandoutNobel
Essential tremor: A heterogenous disorder
2002
Molecular Biology of Prion Diseases
1991 StandoutScienceNobel
COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform
1997 StandoutNobel
A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission
2003 StandoutNobel
Inherited prion diseases.
1994 StandoutNobel
Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neurons.
1995
Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): cleavage of APP occurs in a late compartment of the default secretion pathway.
1993
Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.
1994
Expression of vasopressin receptors in hamster hypothalamus is sexually dimorphic and dependent upon photoperiod.
1991 StandoutNobel
Works of Ron Tintner being referenced
Dystonia and parkinsonism
2001
Pleuropulmonary Fibrosis After Long-term Treatment With the Dopamine Agonist Pergolide for Parkinson Disease
2005
Striatal deformities of the hand and foot in Parkinson's disease
2005
Intrafamilial phenotypic variability of the DYT1 dystonia: From asymptomatic TOR1A gene carrier status to dystonic storm
2002
Behavioral responses to intracerebroventricularly administered neurohypophyseal peptides in mice
1978
Neuropathologic verification of Creutzfeldt‐Jakob disease in the exhumed American recipient of human pituitary growth hormone
1986 Nobel
Production of the Alzheimer Amyloid β Protein by Normal Proteolytic Processing
1992 StandoutScience